Publications

Ziv O, Diamant N, Shachar S, Hendel A, Livneh Z (2012).
Quantitative Measurement of Translesion Dna Synthesis in Mammalian Cells.
Methods in Molecular Biology ,920,529-542.
Diamant N, Hendel A, Vered I, Carell T, Reissner T, de Wind N, Geacinov N, Livneh Z. (2012).
Dna Damage Bypass Operates in the s and g2 Phases of the Cell Cycle and Exhibits Differential Mutagenicity.
Nucleic Acids Research ,40(1),170-180.
Leitner-Dagan Y, Sevilya Z, Pinchev M, Kramer R, Elinger D, Roisman LC, Rennert HS, Schechtman E, Freedman L, Rennert G, Livneh Z, Paz-Elizur T. (2012).
N-Methylpurine Dna Glycosylase and Ogg1 Dna Repair Activities: Opposite Associations With Lung Cancer Risk.
Journal of the National Cancer Institute ,104(22),1765-1769.
Hendel A, Krijger PHL, Diamant N, Goren Z, Langerak P, Kim J, Reissner T, Lee KY, Geacintov NE, Carell T, Myung K, Tateishi S, D'Andrea A, Jacobs H, Livneh Z. (2011).
Pcna Ubiquitination is Important, But Not Essential For Translesion Dna Synthesis in Mammalian Cells.
Plos Genetics ,7(9),e1002262.
Livneh Z, Ziv O, Shachar S. (2010).
Multiple Two-Polymerase Mechanisms in Mammalian Translesion Dna Synthesis.
Cell Cycle ,9(4),729-735
Schneider S, Reissner T, Ziv O, Livneh Z, Carell T. (2010).
Translesion Synthesis of 1,3-Gtg Cisplatin Dna Lesions.
Chembiochem ,11(11),1521-1524.
Jansen JG, Tsaalbi-Shtylik A, Hendriks G, Gali H, Hendel A, Johansson F, Erixon K, Livneh Z, Mullenders LHF, Haracska L, de Wind N. (2009).
Separate Domains of Rev1 Mediate Two Modes of Dna Damage Bypass in Mammalian Cells.
Molecular and Cellular Biology ,29(11),3113-3123.
Ziv O, Geacintov N, Nakajima S, Yasui A, Livneh Z. (2009).
Dna Polymerase Zeta Cooperates With Polymerases Kappa and Iota in Translesion Dna Synthesis Across Pyrimidine Photodimers in Cells From Xpv Patients.
Proceedings of the National Academy of Sciences of the United States of America ,106(28),11552-11557.
Covo S, de Villartay JP, Jeggo PA, Livneh Z. (2009).
Translesion Dna Synthesis-Assisted Non-Homologous End-Joining of Complex Double-Strand Breaks Prevents Loss of Dna Sequences in Mammalian Cells.
Nucleic Acids Research ,37(20),6737-6745.
Adar S, Izhar L, Hendel A, Geacintov N, Livneh Z. (2009).
Repair of Gaps Opposite Lesions by Homologous Recombination in Mammalian Cells.
Nucleic Acids Research ,37(17),5737-5748.
Shachar S, Ziv O, Avkin S, Adar S, Wittschieben J, Reissner T, Chaney S, Friedberg EC, Wang ZG, Carell T, Geacintov N, Livneh Z. (2009).
Two-Polymerase Mechanisms Dictate Error-Free and Error-Prone Translesion Dna Synthesis in Mammals.
EMBO Journal ,28(4),383-393.
Izhar L, Goldsmith M, Dahan R, Geacintov N, Lloyd RG, Livneh Z. (2008).
Analysis of Strand Transfer and Template Switching Mechanisms of Dna Gap Repair by Homologous Recombination in Escherichia Coli: Predominance of Strand Transfer.
Journal of Molecular Biology ,381(4),803-809.
Hendel A, Ziv O, Gueranger Q, Geacintov N, Livneh Z. (2008).
Reduced Efficiency and Increased Mutagenicity of Translesion Dna Synthesis Across a tt Cyclobutane Pyrimidine Dimer, But Not a tt 6-4 Photoproduct, in Human Cells Lacking Dna Polymerase Eta.
Dna RepaIR ,7(10),1636-1646.
Paz-Elizur T, Sevilya Z, Leitner-Dagan Y, Schechtman E, Barnett-Griness O, Almog R, Rennert G, Livneh Z. (2008).
Harnessing Dna Repair Enzyme Activity For Use as Biomarkers For Risk Assessment and Early Detection of Lung Cancer.
Cancer Biomarkers ,4(3),150-151
Arad G, Hendel A, Urbanke C, Curth U, Livneh Z. (2008).
Single-Stranded Dna-Binding Protein Recruits Dna Polymerase v to Primer Termini on Reca-Coated DNA.
Journal of Biological Chemistry ,283(13),8274-8282.
Paz-Elizur T, Sevilya Z, Leitner-Dagan Y, Elinger D, Roisman LC, Livneh Z. (2008).
Dna Repair of Oxidative Dna Damage in Human Carcinogenesis: Potential Application For Cancer Risk Assessment and Prevention.
Cancer Letters ,266(1),60-72.
Paz-Elizur T, Elinger D, Leitner-Dagan Y, Blumenstein S, Krupsky M, Berrebi A, Schechtman E, Livneh Z. (2007).
Development of an Enzymatic Dna Repair Assay For Molecular Epidemiology Studies: Distribution of Ogg Activity in Healthy Individuals.
Dna RepaIR ,6(1),45-60.
Paz-Elizur T, Elinger D, Ben-Yosef R, Krupsky M, Leitner-Dagan Y, Vexler A, Svilya Z, Schechtman E, Freedman L, Livneh Z (2007).
Repair of Oxidative-Dna Damage and the Risk of Smoking-Related Cancers..
Environmental and Molecular Mutagenesis ,48(7),553.
Livneh Z (2006).
Keeping Mammalian Mutation Load in Check - Regulation of the Activity of Error-Prone Dna Polymerases by P53 and P21.
Cell Cycle ,5(17),1918-1922.
Paz-Elizur T, Ben-Yosef R, Elinger D, Vexler A, Krupsky M, Berrebi A, Shani A, Schechtman E, Freedman L, Livneh Z. (2006).
Reduced Repair of the Oxidative 8-Oxoguanine Dna Damage and Risk of Head and Neck Cancer.
Cancer Research ,66(24),11683-11689.
Adar S, Livneh Z (2006).
Translesion Dna Synthesis Across Non-Dna Segments in Cultured Human Cells.
Dna RepaIR ,5(4),479-490.
Avkin S, Sevilya Z, Toube L, Geacintov N, Chaney SG, Oren M, Livneh Z. (2006).
P53 and P21 Regulate Error-Prone Dna Repair to Yield a Lower Mutation Load.
Molecular Cell ,22(3),407-413.
Leloup C, Garty G, Assaf G, Cristovao A, Breskin A, Chechik R, Shchemelinin S, Paz-Elizur T, Livneh Z, Schulte RW, Bashkirov V, Milligan JR, Grosswendt B (2005).
Evaluation of Lesion Clustering in Irradiated Plasmid DNA.
International Journal of Radiation Biology ,81(1),41-54.
Paz-Elizur T, Brenner DE, Livneh Z (2005).
Interrogating Dna Repair in Cancer Risk Assessment.
Cancer Epidemiology Biomarkers & Prevention ,14(7),1585-1587.
Covo S, Blanco L, Livneh Z (2004).
Lesion Bypass by Human Dna Polymerase mu Reveals a Template-Dependent, Sequence-Independent Nucleotidyl Transferase Activity.
Journal of Biological Chemistry ,279(2),859-865.
Avkin S, Goldsmith M, Velasco-Miguel S, Geacintov N, Friedberg EC, Livneh Z (2004).
Quantitative Analysis of Translesion Dna Synthesis Across a Benzo[a] Pyrene-Guanine Adduct in Mammalian Cells - the Role of Dna Polymerase Kappa.
Journal of Biological Chemistry ,279(51),53298-53305.
Benenson Y, Adar R, Paz-Elizur T, Livneh Z, Shapiro E (2003).
Dna Molecule Provides a Computing Machine With Both Data and Fuel.
Proceedings of the National Academy of Sciences of the United States of America ,100(5),2191-2196.
Paz-Elizur T, Krupsky M, Blumenstein S, Elinger D, Schechtman E, Livneh Z (2003).
Dna Repair Activity For Oxidative Damage and Risk of Lung Cancer.
Journal of the National Cancer Institute ,95(17),1312-1319
Maor-Shoshani A, Hayashi K, Ohmori H, Livneh Z (2003).
Analysis of Translesion Replication Across an Abasic Site by Dna Polymerase iv of Escherichia Coli.
Dna RepaIR ,2(11),1227-1238.
Maor-Shoshani A, Ben-Ari V, Livneh Z (2003).
Lesion Bypass Dna Polymerases Replicate Across Non-Dna Segments.
Proceedings of the National Academy of Sciences of the United States of America ,100(25),14760-14765.
Avkin Sharon, Adar Sheera, Blander Gil, Livneh Zvi (2002).
Quantitative Measurement of Translesion Replication in Human Cells: Evidence For Bypass of Abasic Sites by a Replicative Dna Polymerase..
Proceedings of the National Academy of Sciences of the United States of America ,99(6),3764-9.
Avkin Sharon, Livneh Zvi (2002).
Efficiency, Specificity and Dna Polymerase-Dependence of Translesion Replication Across the Oxidative Dna Lesion 8-Oxoguanine in Human Cells..
Mutation Research ,510(1-2),81-90.
Maor-Shoshani Ayelet, Livneh Zvi, et al (2002).
Analysis of the Stimulation of Dna Polymerase v of Escherichia Coli by Processivity Proteins..
Biochemistry ,41(48),14438-46.
Berdichevsky Ala, Izhar Lior, Livneh Zvi, et al (2002).
Error-Free Recombinational Repair Predominates Over Mutagenic Translesion Replication in e. Coli..
Molecular Cell ,10(4),917-24.
Livneh Z (2001).
Dna Damage Control by Novel Dna Polymerases: Translesion Replication and Mutagenesis.
Journal of Biological Chemistry ,276(28),25639-25642.
Reuven NB, Arad G, Stasiak AZ, Stasiak A, Livneh Z (2001).
Lesion Bypass by the Escherichia Coli Dna Polymerase v Requires Assembly of a Reca Nucleoprotein Filament.
Journal of Biological Chemistry ,276(8),5511-5517.
Benenson Y, Paz-Elizur T, Adar R, Keinan E, Livneh Z, Shapiro E (2001).
Programmable and Autonomous Computing Machine Made of Biomolecules.
Nature ,414(6862),430-434.
Ohmori H, Friedberg EC, Fuchs RPP, Goodman MF, Hanaoka F, Hinkle D, Kunkel TA, Lawrence CW, Livneh Z, Nohmi T, Prakash L, Prakash S, Todo T, Walker GC, Wang ZG, Woodgate R (2001).
the y-Family of Dna Polymerases.
Molecular Cell ,8(1),7-8.
Daube SS, Tomer G, Livneh Z (2000).
Translesion Replication by Dna Polymerase Delta Depends on Processivity Accessory Proteins and Differs in Specificity From Dna Polymerase Beta.
Biochemistry ,39(2),348-355.
Daube SS, Arad G, Livneh Z (2000).
Translesion Replication by Dna Polymerase Beta is Modulated by Sequence Context and Stimulated by Fork-Like Flap Structures in DNA.
Biochemistry ,39(2),397-405.
Maor-Shoshani A, Reuven NB, Tomer G, Livneh Z (2000).
Highly Mutagenic Replication by Dna Polymerase v (Umuc) Provides a Mechanistic Basis For Sos Untargeted Mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America ,97(2),565-570.
Goldsmith M, Sarov-Blat L, Livneh Z (2000).
Plasmid-Encoded Mucb Protein is a Dna Polymerase (Pol ri) Specialized For Lesion Bypass in the Presence of Muca ', Reca, and Ssb.
Proceedings of the National Academy of Sciences of the United States of America ,97(21),11227-11231.
Offer H, Wolkowicz R, Matas D, Blumenstein S, Livneh Z, Rotter V (1999).
Direct Involvement of P53 in the Base Excision Repair Pathway of the Dna Repair Machinery.
Febs Letters ,450(3),197-204.
Reuven NB, Arad G, Maor-Shoshani A, Livneh Z (1999).
The Mutagenesis Protein Umuc is a Dna Polymerase Activated by Umud ', Reca, and Ssb and is Specialized For Translesion Replication.
Journal of Biological Chemistry ,274(45),31763-31766.
Tomer G, Livneh Z. (1999).
Analysis of Unassisted Translesion Replication by the Dna Polymerase Iii Holoenzyme.
Biochemistry ,38(18),5948-5958.
Livneh Z, Paz-Elizur T, Tomer G, Barak Y, Reuven N, Maor A. (1998).
Mechanism and Regulation of Dna Damage-Induced Mutagenesis and Translesion Replication.
Faseb Journal ,12(8),247 -
Dahan-Grobgeld E, Livneh Z, Maretzek AF, Polak-Charcon S, Eichenbaum Z, Degani H. (1998).
Reversible Induction of Atp Synthesis by Dna Damage and Repair in Escherichia Coli - in Vivo Nmr Studies.
Journal of Biological Chemistry ,273(46),30232-30238.
Eichenbaum Z, Livneh Z. (1998).
Uv Light Induces Is10 Transposition in Escherichia Coli.
Genetics ,149(3),1173-1181
Reuven NB, Tomer G, Livneh Z. (1998).
The Mutagenesis Proteins Umud ' and Umuc Prevent Lethal Frameshifts While Increasing Base Substitution Mutations.
Molecular Cell ,2(2),191-199.
Sarov-Blat L, Livneh Z. (1998).
The Mutagenesis Protein Mucb Interactions With Single Strand Dna Binding Protein and Induces a Major Conformational Change in Its Complex With Single-Stranded DNA.
Journal of Biological Chemistry ,273(10),5520-5527.
Tomer G, Reuven NB, Livneh Z. (1998).
The Beta Subunit Sliding Dna Clamp is Responsible For Unassisted Mutagenic Translesion Replication by Dna Polymerase Iii Holoenzyme.
Proceedings of the National Academy of Sciences of the United States of America ,95(24),14106-14111.

Earlier Publications

PazElizur T, Barak P, Livneh Z. (1997).
Anti-Mutagenic Activity of Dna Damage-Binding Proteins Mediated by Direct Inhibition of Translesion Replication.
Journal of Biological Chemistry ,272(46),28906-28911.
PazElizur T, Takeshita M, Livneh Z. (1997).
Mechanism of Bypass Synthesis Through an Abasic Site Analog by Dna Polymerase i.
Biochemistry ,36(7),1766-1773.
Skaliter R, Bergstein M, Livneh Z. (1996).
Beta*, a uv-Inducible Shorter Form of the Beta Subunit of Dna Polymerase Iii of Escherichia Coli .2. Overproduction, Purification, and Activity as a Polymerase Processivity ClAMP.
Journal of Biological Chemistry ,271(5),2491-2496.
Tomer G, CohenFix O, ODonnell M, Goodman M, Livneh Z. (1996).
Reconstitution of Repair-Gap uv Mutagenesis With Purified Proteins From Escherichia Coli: a Role For Dna Polymerases Iii and II.
Proceedings of the National Academy of Sciences of the United States of America ,93(4),1376-1380.
PazElizur T, Takeshita M, Goodman M, ODonnell M, Livneh Z. (1996).
Mechanism of Translesion Dna Synthesis by Dna Polymerase ii - Comparison to Dna Polymerases i and Iii Core.
Journal of Biological Chemistry ,271(40),24662-24669.
PazElizur T, Skaliter R, Blumenstein S, Livneh Z. (1996).
Beta*, a uv-Inducible Smaller Form of the Beta Subunit Sliding Clamp of Dna Polymerase Iii of Escherichia Coli .1. Gene Expression and Regulation.
Journal of Biological Chemistry ,271(5),2482-2490.
Skaliter R, PazElizur T, Livneh Z. (1996).
A Smaller Form of the Sliding Clamp Subunit of Dna Polymerase Iii is Induced by uv Irradiation in Escherichia Coli.
Journal of Biological Chemistry ,271(5),2478-2481.
BARAK Y, COHENFIX O, LIVNEH Z. (1995).
Deamination of Cytosine-Containing Pyrimidine Photodimers in uv-Irradiated Dna - Significance For uv-Light Mutagenesis.
Journal of Biological Chemistry ,270(41),24174-24179.
EICHENBAUM Z, LIVNEH Z. (1995).
Intermolecular Transposition of Is10 Causes Coupled Homologous Recombination at the Transposition Site.
Genetics ,140(3),861-874
ELIZUR T, TAKESHITA M, LIVNEH Z. (1995).
Bypass of an Abasic Site in a Defined Gapped Duplex Oligonucleotide.
Journal of Cellular Biochemistry ,,302
LIVNEH Z, BARAK Y. (1995).
Deamination of Cytosine - Containing Cyclobutyl Pyrimidine Photodimers - Significance For uv Mutagenesis.
Journal of Cellular Biochemistry ,,344
COHENFIX O, LIVNEH Z. (1994).
In-Vitro uv Mutagenesis Associated With Nucleotide Excision-Repair Gaps in Escherichia-Coli.
Journal of Biological Chemistry ,269(7),4953-4958
TADMOR Y, BERGSTEIN M, SKALITER R, SHWARTZ H, LIVNEH Z. (1994).
Beta-Subunit of Dna-Polymerase-Iii Holoenzyme is Induced Upon Ultraviolet-Irradiation or Nalidixic-Acid Treatment of Escherichia-Coli.
Mutation Research ,308(1),53-64
LIVNEH Z, COHENFIX O, SKALITER R, ELIZUR T. (1993).
Replication of Damaged Dna and the Molecular Mechanism of Ultraviolet-Light Mutagenesis.
Critical Reviews in Biochemistry and Molecular Biology ,28(6),465-513.
COHENFIX O, LIVNEH Z. (1992).
Biochemical-Analysis of uv Mutagenesis in Escherichia-Coli by Using a Cell-Free Reaction Coupled to a Bioassay - Identification of a Dna Repair-Dependent, Replication-Independent Pathway.
Proceedings of the National Academy of Sciences of the United States of America ,89(8),3300-3304.
SKALITER R, EICHENBAUM Z, SHWARTZ H, ASCARELLIGOELL R, LIVNEH Z. (1992).
Spontaneous Transposition in the Bacteriophage-Lambda Cro Gene Residing on a Plasmid.
Mutation Research ,267(1),139-151
TADMOR Y, ASCARELLIGOELI R, SKALITER R, LIVNEH Z. (1992).
Overproduction of the Beta Subunit of Dna Polymerase-Iii Holoenzyme Reduces uv Mutagenesis in Escherichia-Coli.
Journal of Bacteriology ,174(8),2517-2524
SHAVITT O, LIVNEH Z. (1989).
Rolling-Circle Replication of uv-Irradiated Duplex Dna in the Phi-X174 Replicative-Form-]Single-Strand Replication System Invitro.
Journal of Bacteriology ,171(6),3530-3538
SHWARTZ H, LIVNEH Z. (1989).
Reca Protein Inhibits Invitro Replication of Single-Stranded-Dna With Dna Polymerase-Iii Holoenzyme of Escherichia-Coli.
Mutation Research ,213(2),165-173
SHAVITT O, LIVNEH Z. (1989).
The Beta Subunit Modulates Bypass and Termination at uv Lesions During Invitro Replication With Dna Polymerase-Iii Holoenzyme of Escherichia-Coli.
Journal of Biological Chemistry ,264(19),11275-11281
HEVRONI D, LIVNEH Z. (1988).
Bypass and Termination at Apurinic Sites During Replication of Single-Stranded-Dna Invitro - a Model For Apurinic Site Mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America ,85(14),5046-5050.
SHWARTZ H, SHAVITT O, LIVNEH Z. (1988).
The Role of Exonucleolytic Processing and Polymerase-Dna Association in Bypass of Lesions During Replication Invitro - Significance For Sos-Targeted Mutagenesis.
Journal of Biological Chemistry ,263(34),18277-18285
SHWARTZ H, LIVNEH Z. (1987).
Dynamics of Termination During Invitro Replication of Ultraviolet-Irradiated Dna With Dna Polymerase-Iii Holoenzyme of Escherichia-Coli.
Journal of Biological Chemistry ,262(22),10518-10523
LIVNEH Z. (1986).
Mechanism of Replication of Ultraviolet-Irradiated Single-Stranded-Dna by Dna Polymerase-Iii Holoenzyme of Escherichia-Coli - Implications For Sos Mutagenesis.
Journal of Biological Chemistry ,261(20),9526-9533
LIVNEH Z. (1986).
Replication of uv-Irradiated Single-Stranded-Dna With Dna Polymerase-Iii Holoenzyme - Implications For Sos-Mutagenesis.
Journal of Cellular Biochemistry ,,236
SHWARTZ H, LANDMAN O, LIVNEH Z. (1986).
Uv-Induced Mutagenesis in the Cro Gene of Bacteriophage-Lambda Carried on a Multicopy Plasmid.
British Journal of Cancer ,54(2),374
LIVNEH Z. (1986).
Invitro Replication of uv-Irradiated Dna With Dna Polymerase-Iii Holoenzyme of Escherichia-Coli.
British Journal of Cancer ,54(2),360
LIVNEH Z, LIVNEH E, SPERLING J. (1980).
Specific Photoalkylation of Poly-u and of Poly-a With 2-Propanol and their Messenger Properties.
Photochemistry and Photobiology ,32(2),131-135.
LIVNEH Z, ELAD D, SPERLING J. (1979).
Possible Repair of Purine-Modified DNA.
Israel Journal of Medical Sciences ,15(1),98-99
LIVNEH Z, ELAD D, SPERLING J. (1979).
Endonucleolytic Activity Directed Towards 8-(2-Hydroxy-2-Propyl) Purines in Double-Stranded DNA.
Proceedings of the National Academy of Sciences of the United States of America ,76(11),5500-5504.
LIVNEH Z, ELAD D, SPERLING J. (1979).
Enzymatic Insertion of Purine-Bases Into Depurinated Dna Invitro.
Proceedings of the National Academy of Sciences of the United States of America ,76(3),1089-1093.