Selected Publications

 

Raviv, Z., Kalie, E., and Seger, R. (2004) The subcellular localization of components of the ERK5 cascade. J. Cell Sci. 117, 1773-1784.

 

Yao, Z., and Seger, R. (2004) The molecular mechanism of MAPK/ERK inactivation. Current Genomics 5, 385-393.

 

Kraus, S., Levy, G., Hanoch, T., Naor, Z., and Seger, R. (2004) Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways.  Cancer Res. 64, 5736-5744. Selected for the Cancer Research Highlights in Cancer Res. 64, 5525.

 

Aebersold, D.M., Shaul, Y.D., Yung, Y., Yarom, N., Yao, Z., Hanoch , T., and Seger, R. (2004) ERK1c, a novel 42-kDa ERK demonstrates a unique mode of regulation, localization and function. Mol. Cell Biol.  24, 10000-10015.

 

Chuderland, D., and Seger, R. (2005) Protein-protein interactions in the regulation of the extracellular signal-regulated kinase (ERK).  Mol. Biotechnol.  29, 47-74.

 

Maik-Rachline, G., Shaltiel, S., and Seger, R. (2005) Extracellular phosphorylation converts pigment epithelium-derived factor from a neurotrophic to an antiangiogenic factor. Blood 105, 670-678.

 

Bendetz-Nezer, S., and Seger, R. (2005) Full molecular page of MEK1. AfCS/Nature Signaling Gateway, doi:10.1038/mp.a001505.01.

 

Bendetz-Nezer, S., and Seger, R. (2005) Full molecular page of MEK2. AfCS/Nature Signaling Gateway, doi:10.1038/mp.a001506.01.

 

Maik-Rachline, G., and Seger, R. (2005) The neurotrophic and antiangiogenic functions of PEDF: a reflection of its variable phosphorylation states. Current Genomics 6, 597-607.

 

Yoon, S., and Seger, R. (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24, 21-44.

 

Kraus, S., Naor, Z., and Seger, R. (2006) The GnRH receptor in prostate cancer.  Cancer letters 234, 109-123.

 

Shaul Y.D., and Seger, R. (2006) ERK1c regulates Golgi fragmentation during mitosis. J. Cell Biol. 172, 885-897.

 

Maik-Rachline, G., and Seger, R. (2006) Variable phosphorylation states of pigment epithelium-derived factor differentially regulate its function. Blood 107, 2745-2752.