Publications (from the last 10 years)


1. E. Furman H, M. Margalit, A.F.Maretzek and H. Degani, "Angiogenic response of MCF7 human breast cancer to hormonal treatment: assessment by dynamic GdDTPA enhanced MRI at high spatial resolution", JMRI 6, 195-202, (1996).
2. R. Kumar, Tyagi A. Azrad1, H. Degani and Y. Salomon, "Simultaneous extraction of cellular lipids and water-soluble metabolites: evaluation by NMR spectroscopy", Magn. Reson. Med. 35, 194-200, (1996).
3. E. Furman-Haran, R. Margalit, D. Grobgeld and H. Degani, "Dynamic Contrast Enhanced Magnetic Resonance Imaging Reveals Stress Induced Angiogenesis in MCF7 Human Breast Tumors" Proc. Natl. Acad. Sci. USA, 93, 6247-6251, (1996).
4. Yen-ling T. Ting, D. Sherr and H. Degani,"Variations in the energy and phospholipid metabolism in normal and cancer human mammary epithelial cells" Anticancer Research , 16, 1381-1388, (1996).
5.

R. Katz-Brull and H. Degani, "Kinetics of choline transport and phosphorylation in human breast cancer cells; NMR application of the zero trans method". Anticancer Research, , 16, 1375-1380, (1996).
6. A. Biegon, M Brewster, H. Degani, E. Pop, D. Somjen and A.M. Kay, A permeability Charged tamoxifen derivative disolays Anti-canceractivity and improved tissue selectivity in rodents, Cancer Res. 56, 4328-4331, (1996).
7. C.F. Maier, Y. Paran, P. Bendel, B>K. Rutt and H. Degani, Quantitative Diffusion in Implanted Human breast Tumors. Magn. Reson. Med. 37, 576-581, (1997).
8. H. Degani, V. Gusis, D. Weinstein, S. Fields and S. Strano, Mapping pathophysiological features of breast tumors by MRI at high spatial resolution, Nature Medicine 3, 780-782, (1997).
9. M.E. Brewster, Y. Paran, E. Rushkin, A. Biegon, E. Pop and H. Degani, Evaluation of the anticancer action of a permanently charged tamoxifen derivative, tamoxifen methiodide: an MRI study. Int. J. Pharm. 153, 147-157, (1997).
10. E. Furman Haran, D. Grobgeld and H. Degani, Dynamic Contrast Enhanced Imaging and Analysis at High Spatial resolution of MCF7 Human breast Tumors J. Magn. Reson. 128, 161-171 (1997).
11. E. Furman-Haran, R. Margalit, D. Grobgeld and H. Degani, "High Resolution MRI of MCF7 Human Breast Tumors: Complemented use of Iron Oxide". J. Magn. Reson. Imag., 8, 634-641, (1998).
12. D. M. Ojcius, H. Degani, J. Mispelter and A. Dautry-Varsat, Enhancement of ATP levels and glucose metabolism during an infection by Chlamydia : NMR studies of living cells. J. Biol. Chem.., 273, 7052-7058, (1998).
13. R. Katz-brull, R. Margalit, P. Bendel and H. Degani, Choline metabolism in breast cancer; 2H, 13C & 31P NMR studies of cells and tumors, MAG*MA, 6, 44-52, (1998).
14. L. Bogin, M. Z. Papa, S. Polak-Charcon, and H. Degani. TNF modulations of membrane associated enzymes in human breast cancer cells: NMR studies. Biochem. Biophys. Acta , 1392, 217-232, (1998).
15. E. Dahan-Grobgeld, Z. Livneh, A. F. Maretzek, S. Polak-Charcon, Z. Eichenbaum, and H.Degani. Reversible Induction of ATP synthesis by DNA Damage and Repair in E. coli; In vivo NMR Studies. J. Biol. Chem., 273, 30232-30238, (1998).
16. E. Furman-Haran, D. Grobgeld and H. Degani, Decreased cellular volume fraction and increased microvascular permeability indicate response of MCF7 xenografts to tamoxifen; application of the 3 time point contrast enhanced MRI method, Clinical Cancer Reseach, 4, 2299-2304, (1998).
17. R.K. Tyagi, A. Azrad, H. Degani and Y. salomon, Stimulation of fructose 1,6,-bisphosphate production in melanoma cells by alpha-melanocyte-stimulating hormone;31P/13C-NMR and 32P-labeling studies. Eur. J. Biochem., 258, 68-77, (1998).
18. M. Peled-kamar, H. Degani, P. bendel, R. Margalit and Y. groner, Altered brain glucose metabolism in transgenic-PFKL mice with elevated L-phosphofructokinase: in vivo NMR studies, Brain Res. 810, 138-145, (1998).
19. D. Weinstein, S, Strano, P. Cohen, S. Fields, J. M. Gomori, and H. Degani, Mapping Pathophysiologic Features of Breast Fibroadenoma by the Three Time Point (3TP) Contrast Enhanced MRI Method; Pilot Study, Radiology, 210, 233-40, (1999).
20. N. Maril, H. Degani, E. Rushkin, A. D. Sherry and M. Cohn, The mechanism of Cyclocreatine Activity in Human breast Cancer cells; Kinetics of Cyclocreatine and Sodium Co-Transport, Am J Physiol 277: C708-16, (1999).
21. D. Rivenzon-Segal, E. Rushkin, S. Polak-Charcon and H. Degani, “Glucose transporters and transport kinetics in retinoic acid-differentiated T47D human breast cancer cells”. Am J Physiol (Endocrinol Metab), 279, E508-E519, (2000).
22. E. Furman-Haran, D. Grobgeld, F. Kelez and H. Degani, “The critical role of spatial resolution in dynamic contrast enhanced breast MRI”. J Magn. Res. Imaging, 13, 862-867, (2001).
23. R. Katz-Brull, R. Margalit and H. Degani, “Differential Routing of choline in implanted breast cancer and normal organs” Magn Reson Med, 46, 31-38, (2001).
24. D.M. Ikeda, N.M. Hilton, K. Kinkel, M.G. Hochman, C.K. Kuhl, W.A.Kaiser, J.C. Weinreb, S.F. Smazal, H. Degani, P. Viehweg, J. Barclay, M.D. Schnall. “Development, standardization, and testing of a lexicon for reporting contrast enhanced breast magnetic resonance imaging studies”. J. Magn. Reson. Imaging. 13, 889-895, (2001).
25. R. Katz-Brull, D. Seger, D. Rivenson-Segal, E. Rushkin and H. Degani, Metabolic markers of breast cancer: enhanced choline metabolism and reduced choline-ether- phospholipid synthesis. Cancer Res. 62, 1966-70, (2002).
26. L. Bogin and H. Degani, Hormonal Regulation of VEGF in Orthotopic MCF7 Human Breast Cancer, Cancer Res 62, 1948-51, (2002).
27. E. Furman Haran and H. Degani, Parametric analysis of breast MRI, J Comput Assist Tomogr; Review. 26: 376-386, (2002).
28. L. Bogin , R. Margalit, H. Ristau, J. Mispelter and H. Degani, Parametric imaging of tumor perfusion with deuterium magnetic resonance imaging, Microvasc Res. 64: 104-115, (2002).
29. S. Walenta, B. Feigk, I. Wachsmuth, T. Dunkern, H. Degani, W. Mueller-Klieser., Differential changes in purine nucleotides after Doxorubicin treatment of human cancer cells in vitro, Int J Oncol. 21: 289-296, (2002).
30. D. Rivenzon-Segal, R. Margalit and H. Degani, Glycolysis as a metabolic marker in orthotopic breast cancer, monitored by in vivo 13C MRS, Am. J Physiol. Endocrinology and Metabolism, 283, E623-E630, (2002).
31. L. Bogin, R. Margalit, J. Mispelter, and H. Degani, Parametric Imaging of Tumor Perfusion Using Flow- and Permeability-Limited Tracers J. Magn. Reson. Imaging, 16, 289-299, (2002).
32. R. Katz-Brull, A. R. Kudinov, and H. Degani, Choline in the aging brain, Brain Res., 951:158-65, (2002).
33. F. Kelcz, E. Furman-Haran, D. Grobgeld, H. Degani, Clinical Testing of a High Spatial Resolution, Parametric, Contrast-Enhanced Method, for Breast MRI Diagnosis, Am J Roentgenol. 179: 1485-92, (2002).
34. E. Furman-Haran, F. Kelcz , H. Degani Magnetic resonance imaging of breast cancer angiogenesis: a review. J Exp Clin Cancer Res.
21(3 Suppl):47-54, (2002).
35. H. Degani, M. Chetrit-Dadiani, L. Bogin, and E. Furman-Haran, “Magnetic Resonance Imaging of Tumor Vasculature” Thromb Haemost. 89: 25-33, (2003).
36. Y Paran, S.A. Adamsky Boldin, R. Margalit, H. Degani, “Diffusion-weighted MRI and response to anti-cancer therapies” Israel J Chem 43: 103-114, (2003).
37. D. Rivenzon-Segal, S. Boldin-Adamsky, D. Seger, R. Seger, H. Degani.
“Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer”. Int J Cancer. 107:177-82, (2003).
38. N. Maril, R. Margalit, J. Mispelter, H. Degani. “Functional sodium magnetic resonance imaging of the intact rat kidney”. Kidney Int. 65:927-35, (2004).
39. M. Dadiani, R. Margalit, N. Sela, H. Degani, “High resolution magnetic resonance imaging of disparities in the transcapillary transfer rates in orthotopically inoculated breast tumors”, Cancer Res, 64:3155-61, (2004).
40. Y. Paran, P. Bendel, R. Margalit, and H. Degani. “Water diffusion in the different microenvironments of breast cancer”, NMR in Biomed, 17:170-80, (2004).
41. N. Sela, H. Degani, L. Frydman. « Ultrafast 2D NMR spectroscopy using sinusoidal gradients : principles and ex vivo brain investigations. Magn Reson Med, 52, 893-897, (2004).
42. N. Maril, R Margalit, J Mispelter and H Degani, Sodium MRI of Diuresis: Spatial and Kinetic Response, Magn Reson Med, 53:545-52 (2005).
43. R. Katz-Brull, A.R. Koudinov and H. Degani, Direct detection of brain acetylcholine synthesis by magnetic resonance spectroscopy, Brain Res. , 1048(1-2):202-10, (2005)
44. E.Furman-Haran, E. Schechtman, F. Kelcz; K. Kirshenbaum, and H. Degani. MRI Reveals Functional Diversity of the Vasculature in Benign and Malignant Breast Lesions. Cancer, 15;104(4):708-18 (2005).
45. N. Maril, R. Margalit, S. Rosen, S.N. Heyman , H. Degani, 123Na MRI Study of the Renal Sodium Distribution at an Early Phase of ARF in the Rat Kidney, in press, Kidney Int, 69, 765-768 (2006).
46. Y. Hassid, E. Furman Haran, R. Margalit, R. Eilam, H. Degani, Non invasive magnetic resonance imaging of transport and interstial fluid pressure in ectopic human lung cancer, Cancer Res. 66:4159-66, (2006).
47. Y. Rosen, G. Ramniceanu, R. Margalit, D Grobgeld, R. Eilam R, H. Degani, E. Furman-Haran, Vascular perfusion of human lung cancer in a rat orthotopic model using dynamic contrast-enhanced magnetic resonance imaging. Int J Cancer, 119: 365-72, (2006).
48. N. Papo, D. Seger, A. Makovitski, V. Kalchenko, Z. Eshhar, H. Degani , Y. Shai. Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide. Cancer Res. 15;66:5371-8, (2006).
49. M. Dadiani, V. Kalchenko, Y. Yosephovitvh, R. margalit. Y Hassid, H. Degani, D. Seger. Real-time imaging of lymphogenic metastasis in orthotopic human breast cancer, Cancer Res. 66: 8037-8041, (2006).
50. G. Eliyahu, T. kreizman, H. Degani. Phosphocholine as a biomarker of breast cancer: molecular and biochemical studies, Int. J. Cancer 2006, in press.