MASSPEC publications

List of publications of acknowledging Biological Mass Spectrometry Unit & co-authership

  1. Kuster B, Shainskaya A, Pu HX, Goldshleger R, Blostein R, Mann M, Karlish S.J. A new variant of the gamma subunit of renal Na,K-ATPase. Identification by mass spectrometry, antibody binding, and exp ression in cultured cells. J Biol Chem. 2000 Jun 16;275(24):18441-6
     
  2. Burgess HA, Reiner O. Alternative splice variants of doublecortin-like kinase are differentiall y expressed and have different kinase activities. J Biol Chem. 2002 May 17;277(20):17696-705
     
  3. Patchornik G, Munson K, Goldshleger R, Shainskaya A, Sachs G, Karlish S.J. The ATP-Mg2+ binding site and cytoplasmic domain interactions of Na+,K+-ATPase investigated with Fe2+-catalyzed oxidative c leavage and molecular modeling. Biochemistry. 2002 Oct 1;41(39):11740-9
     
  4. Shechter Y, Tsubery H, Fridkin M. N-[(2-Sulfo)-9-fluorenylmethoxycarbonyl](3)-gentamicin C(1) i s a long-acting prodrug derivative. J Med Chem. 2002 Sep 12;45(19):4264-70
     
  5. Amitai G, Belenkiy O, Dassa B, Shainskaya A, Pietrokovski S. Distribution and function of new b acterial intein-like protein domains.Mol Microbiol. 2003 Jan;47(1):61-73
     
  6. Zchut S, Weiss M, Pick U. Temperature-regulated expression of a glycine-rich RNA-binding protei n in the halotolerant alga Dunaliella salina. J Plant Physiol. 2003 Nov;160(11):1375-84
     
  7. Scherz-Shouval R, Sagiv Y, Shorer H, Elazar Z. The COOH terminus of GATE-16, an intra-Golgi tra nsport modulator, is cleaved by the human cysteine protease HsApg4A. J Biol Chem. 2003 Apr 18;278(16):1 4053-8
     
  8. Shechter Y, Tsubery H, Fridkin M. Suspensions of pro-drug insulin greatly prolong normoglycemic patterns in diabetic rats. Biochem Biophys Res Commun. 2003 Jul 25;307(2):315
     
  9. Shechter Y, Tsubery H, Fridkin M. 2-Sulfo-9-fluorenylmethoxycarbonyl]3-exendin-4-a long-acting glucose-lowering prodrug. Biochem Biophys Res Commun. 2003 May 30;305(2):386-91
     
  10. Nery JG, Bolbach G, Weissbuch I, Lahav M. Generation of oligopeptides with homochiral sequences by topochemical reactions within racemic crystals of phenylalanine-N-carboxyanhydride. Angew Chem Int Ed Engl. 2003 May 16;42(19):2157-61
     
  11. Szyper-Kravitz M, Uziel O, Shapiro H, Radnay J, Katz T, Rowe JM, Lishner M, Lahav M. Granulocyt e colony-stimulating factor administration upregulates telomerase activity in CD34+ haematopoietic cell s and may prevent telomere attrition after chemotherapy. Br J Haematol. 2003 Jan;120(2):329-36
     
  12. Szyper-Kravitz M, Uziel O, Shapiro H, Radnay J, Katz T, Rowe JM, Lishner M, Lahav M. Granulocyt e colony-stimulating factor administration upregulates telomerase activity in CD34+ haematopoietic cell s and may prevent telomere attrition after chemotherapy. Br J Haematol. 2003 Jan;120(2):329-36
     
  13. Litvak V, Argov R, Dahan N, Ramachandran S, Amarilio R, Shainskaya A, Lev S. Mitotic phosphoryl ation of the peripheral Golgi protein Nir2 by Cdk1 provides a docking mechanism for Plk1 and affects cy tokinesis completion. Mol Cell. 2004 May 7;14(3):319-30
     
  14. arak R, Prasad K, Shainskaya A, Wolfe AJ, Eisenbach M. Acetylation of the chemotaxis response regulator CheY by acetyl-CoA synthetase purified from Escherichia coli. J Mol Biol. 2004 Sep 10;342(2): 383-401
     
  15. Dassa B, Haviv H, Amitai G, Pietrokovski S. Protein splicing and auto-cleavage of bacterial int ein-like domains lacking a C'-flanking nucleophilic residue. J Biol Chem. 2004 Jul 30;279(31):32001-7
     
  16. Mukamel Z, Kimchi A. Death-associated protein 3 localizes to the mitochondria and is involved i n the process of mitochondrial fragmentation during cell death. J Biol Chem. 2004 Aug 27;279(35):36732- 8
     
  17. Montigny C, Jaxel C, Shainskaya A, Vinh J, Labas V, Moller JV, Karlish SJ, le Maire M. Fe2+ -ca talyzed oxidative cleavages of Ca2+ -ATPase reveal novel features of its pumping mechanism. J Biol Chem . 2004 Oct 15;279(42):43971-81
     
  18. Tsubery H, Mironchik M, Fridkin M, Shechter Y. Prolonging the action of protein and peptide dru gs by a novel approach of reversible polyethylene glycol modification. J Biol Chem. 2004 Sep 10;279(37) :38118-24
     
  19. Mazooz G, Mehlman T, Lai TS, Greenberg CS, Dewhirst MW, Neeman M. Development of magnetic reson ance imaging contrast material for in vivo mapping of tissue transglutaminase activity. Cancer Res. 200 5 Feb 15;65(4):1369-75
     
  20. Libros-Ziv P, Villalobo E, Mirelman D. Entamoeba histolytica: identification and characterizati on of an N-ethylmaleimide sensitive fusion protein homologue. Exp Parasitol. 2005 Jul;110(3):276-9
     
  21. Cohen E, Goldshleger R, Shainskaya A, Tal DM, Ebel C, le Maire M, Karlish SJ.D., Purification o f Na+,K+-ATPase expressed in Pichia pastoris reveals an essential role of phospholipid-protein interact ions. J Biol Chem. 2005 Apr 29;280(17):16610-8
     
  22. Lahiri S, Futerman AH. LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor. J Biol Chem. 2005 Oct 7;280(40):33735-8
     
  23. Fuzesi M, Gottschalk KE, Lindzen M, Shainskaya A, Kuster B, Garty H, Karlish SJ. Covalent cross -links between the gamma subunit (FXYD2) and alpha and beta subunits of Na,K-ATPase: modeling the alpha -gamma interaction. J Biol Chem. 2005 May 6;280(18):18291-301
     
  24. Barak R, Yan J, Shainskaya A, Eisenbach M. (2006 ) The chemotaxis response regulator CheY can c atalyze its own acetylation. J Mol Biol. Jun 2;359(2):251-65
     
  25. Nery JG, Eliash R, Bolbach G, Weissbuch I, Lahav M. Homochiral oligopeptides via surface recogn ition and enantiomeric cross impediment in the polymerization of racemic phenylalanine N-carboxyanhydri de crystals suspended in water. Chirality. 2007 Aug;19(8):612-24
     
  26. Eliash R, Nery JG, Rubinstein I, Clodic G, Bolbach G, Weissbuch I, Lahav M. Homochiral oligopep tides via a lattice-controlled polymerisation in racemic crystals of valine N-carboxyanhydride suspende d in aqueous solutions. Chemistry. 2007;13(36):10140-51
     
  27. Tsruya R, Wojtalla A, Carmon S, Yogev S, Reich A, Bibi E, Merdes G, Schejter E, Shilo BZ. Rhomb oid cleaves Star to regulate the levels of secreted Spitz. EMBO J. 2007 Mar 7;26(5):1211-20.
     
  28. Patchornik G. Double-modified albumins as a tool for antibody purification. J Biochem Biophys M ethods. 2007 Jun 10;70(4):671-3
     
  29. Sevier CS, Qu H, Heldman N, Gross E, Fass D, Kaiser CA. (2007) Modulation of cellular disulfide -bond formation and the ER redox environment by feedback regulation of Ero1. Cell. Apr 20;129(2):333-44 .
     
  30. Bialik S, Berissi H, Kimchi A. (2008) A high throughput proteomics screen identifies novel subs trates of death-associated protein kinase. Mol Cell Proteomics. Jun;7(6):1089-98
     
  31. Illos RA, Bisogno FR, Clodic G, Bolbach G, Weissbuch I, Lahav M. (2008) Oligopeptides and copep tides of homochiral sequence, via beta-sheets, from mixtures of racemic alpha-amino acids, in a one-pot reaction in water; relevance to biochirogenesis. J Am Chem Soc. Jul 9;130(27):8651-9
     
  32. Chuderland D, Marmor G, Shainskaya A, Seger R. (2008) Calcium-mediated interactions regulate th e subcellular localization of extracellular signal-regulated kinases. J Biol Chem. Apr 25; 283(17):1117 6-88
     
  33. Yan J, Barak R, Liarzi O, Shainskaya A, Eisenbach M. (2008) In vivo acetylation of CheY, a resp onse regulator in chemotaxis of Escherichia coli. J Mol Biol. Mar 7; 376(5):1260-71
     
  34. Rott R, Szargel R, Haskin J, Shani V, Shainskaya A, Manov I, Liani E, Avraham E, Engelender S. (2008 ) Monoubiquitylation of alpha-synuclein by seven in absentia homolog (SIAH) promotes its aggregat ion in dopaminergic cells. J Biol Chem. Feb 8; 283(6):3316-28
     
  35. Avidan O, Kaltageser E, Pechatnikov I, Wexler HM, Shainskaya A, Nitzan Y. (2008) Isolation and characterization of porins from Desulfovibrio piger and Bilophila wadsworthia: structure and gene seque ncing. Arch Microbiol. Aug 16
     
  36. Kache.Y, Brumshtein B, Boldin-Adamsky S; Toker L, Shainskaya A, Silman, I, Sussman J.L, Futerm an A.H. (2008) Acid- beta-glucosidase: insights from structural analysis and relevance to Gaucher dise ase therapy. Biological Chemistry. Nov;389(11):1361-9
     
  37. Bab-Dinitz, E., Albeck, S., Peleg, Y., Brumfeld, V., Gottschalk, K.E. & Karlish, S.J. (2009) A C-terminal lobe of the beta subunit of Na,K-ATPase and H,K-ATPase resembles cell adhesion molecules. Biochemistry 48(36):8684-91
     
  38. Zeev-Ben-Mordehai, T., Mylonas, E., Paz, A., Peleg, Y., Toker, L., Silman, I., Svergun, D.I., Sussman, J.L. (2009) The Quaternary Structure of Amalgam, a Drosophila Neuronal Adhesion Protein, Explains Its Dual Adhesion Properties. Biophys J 97, 2316-232
     
  39. Sharabi, O., Peleg, Y., Mashiach, E., Vardy, E., Ashani, Y., Silman, I., Sussman, J.L. & Shifman, J.M. (2009) Design, expression, and characterization of fasciculin mutants optimized for interactions with its target, acetyl cholinesterase PEDS. Protein Eng Des Sel. 22(10): 641-648
     
  40. Heldman, N, Vonshak, O, Sevier CS, Vitu, E, Mehlman, T, Fass, D. (2010) Steps in reductive activation of the disulfide-generating enzyme Ero1p. Protein Sci. 19(10):1863-76
     
  41. Liarzi, O, Barak, R, Bronner, V, Dines, M, Sagi, Y, Shainskaya, M, Eisenbach, M. (2010) "Acetylation the binding of CheY to its target protein." J Mol Biol. 76(4), 932-943
     
  42. Boura-Halfon, S, Shuster-Meiseles, T, Beck, A, Petrovich, K, Gurevitch, D, Ronen, D, Zick, Y. (2010) A novel domain mediates insulin-induced proteasomal degradation of insulin receptor substrate 1 (IRS-1). Mol Endocrinol. 24(11):2179-92
     
  43. Gertler, G, Fleminger, G, Rapaport, H. (2010). Characterizing the adsorption of peptides to TiO2 in aqueous solutions by liquid chromatography. Langmuir. 26(9):6457-63
     
  44. Kaplan A, Reiner O, (2011) Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein. JOURNAL OF CELL SCIENCE 124 : 3989-4000
     
  45. Levy-Barda, A, Lerenthal, Y, Davis AJ, Chung, YM, Essers, J, Shao, Z, van Vliet, N, Chen DJ, Hu, MC, Kanaar, R, Ziv Y, Shiloh, Y. (2011) Involvement of the nuclear proteasome activator PA28? in the cellular response to DNA double-strand breaks. Cell Cycle. 10(24):4300-10
     
  46. Segal-Raz, H, Mass, G, Baranes-Bachar, K, Lerenthal, Y, Wang, SY, Chung, YM, Ziv-Lehrman, S, Str?m, CE, Helleday, T, Hu, MC, Chen, DJ, Shiloh, Y. (2011) ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair. EMBO Rep. 12(7):713-9
     
  47. Levy-Barda, A, Lerenthal, Y, Davis AJ, Chung, YM, Essers, J, Shao, Z, van Vliet, N, Chen DJ, Hu, MC, Kanaar, R, Ziv Y, Shiloh, Y. (2011) Involvement of the nuclear proteasome activator PA28? in the cellular response to DNA double-strand breaks. Cell Cycle. 10(24):4300-10
     
  48. Segal-Raz, H, Mass, G, Baranes-Bachar, K, Lerenthal, Y, Wang, SY, Chung, YM, Ziv-Lehrman, S, Str?m, CE, Helleday, T, Hu, MC, Chen, DJ, Shiloh, Y. (2011) ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair. EMBO Rep. 12(7):713-9
     
  49. Niv-Spector, L, Shpilman, M, Boisclair, Y, Gertler, A.( 2012) Large-scale preparation and characterization of non-pegylated and pegylated superactive ovine leptin antagonist. Protein Expr Purif. 81(2):186-92
     
  50. Shabbeer S, Omer D, Berneman D, Weitzman O, Alpaugh A, Pietraszkiewicz A, Metsuyanim S, Shainskaya A, Papa MZ, Yarden RI. (2012 ) BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradation. Oncogene. Dec 17. doi: 10.1038/onc.2012.522
     
  51. Shirak A, Reicher S, Uliel S, Mehlman T, Shainskaya A, Ron M, Seroussi E. (2012) Gender and sexual behavior modulate the composition of serum lipocalins in Nile tilapia (Oreochromis niloticus). Gene. Aug 1;504(1):22-30
     
  52. Limor-Waisberg K, Alon A, Mehlman T, Fass D. (2012) Phylogenetics and enzymology of plant quiescin sulfhydryl oxidase. FEBS Lett. Nov 30;586(23):4119-25
     
  53. Alon A, Grossman I, Gat Y, Kodali VK, DiMaio F, Mehlman T, Haran G, Baker D, Thorpe C, Fass D. (2012 ) The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature. Aug 16;488(7411):414-8
     
  54. Moscovitz O, Tsvetkov P, Hazan N, Michaelevski I, Keisar H, Ben-Nissan G, Shaul Y, Sharon M. (2012) A mutually inhibitory feedback loop between the 20S proteasome and its regulator, NQO1. Mol Cell. 2012 Jul 13;47(1):76-86
     
  55. Shtenberg G, Massad-Ivanir N, Moscovitz O, Engin S, Sharon M, Fruk L, Segal E. (2013) Picking up the pieces: a generic porous Si biosensor for probing the proteolytic products of enzymes. Anal Chem. Feb 5;85(3):1951-6
     
  56. Isaac R, Boura-Halfon S, Gurevitch D, Shainskaya A, Levkovitz Y, Zick Y. (2013) Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic ? cells. J Biol Chem. Feb 22; 288(8):5682-93