Publications

2017

Habeck, M; Kapri-Pardes, E; Sharon, M; Karlish, Sjd (2017). Specific Phospholipid Binding to na,k-Atpase at Two Distinct Sites.  Proceedings of the National Academy of Sciences of the United States of America. 114:2904-2909.  Abstract
Gan, Jr; Ben-Nissan, G; Arkind, G; Tarnavsky, M; Trudeau, D; Garcia, Ln; Tawfik, Ds; Sharon, M (2017). Native Mass Spectrometry of Recombinant Proteins from Crude Cell Lysates.  Analytical Chemistry. 89:4398-4404.  Abstract
Ben-Nissan, G; Belov, Me; Morgenstern, D; Levin, Y; Dyrn, O; Arkind, G; Lipson, G; Makarov, Aa; Sharon, M (2017). Triple-Stage Mass Spectrometry Unravels the Heterogeneity of an Endogenous Protein Complex.  Analytical Chemistry. 89:4708-4715.  Abstract
Fradkin, Z; Strasser, D; Heber, O; Rappaport, Ml; Sharon, M; Thomson, Ba; Rahinov, I; Toker, Y; Zajfman, D (2017). Protein and Peptide Cross Sections and Mass Spectra in an Electrostatic Ion Beam Trap.  Journal of Instrumentation. 12.  Abstract
Sokolovski, M; Cveticanin, J; Hayoun, D; Korobko, I; Sharon, M; Horovitz, A (2017). Measuring Inter-Protein Pairwise Interaction Energies from a Single Native Mass Spectrum by Double-Mutant Cycle Analysis.  Nature Communications. 8.  Abstract
Eisenberg, I; Harris, D; Levi-Kalisman, Y; Yochelis, S; Shemesh, A; Ben-Nissan, G; Sharon, M; Raviv, U; Adir, N; Keren, N; Paltiel, Y (2017). Concentration-Based Self-Assembly of Phycocyanin.  Photosynthesis Research. 134:39-49.  Abstract

2016

Ben-Nissan, G; Chotiner, A; Tarnavsky, M; Sharon, M (2016). Structural Characterization of Missense Mutations Using High Resolution Mass Spectrometry: a Case Study of the Parkinson's-Related Protein, DJ-1.  Journal of the American Society For Mass Spectrometry. 27:1062-1070.  Abstract
Marzahn, Mr; Marada, S; Lee, J; Nourse, A; Kenrick, S; Zhao, Hy; Ben-Nissan, G; Kolaitis, Rm; Peters, Jl; Pounds, S; Errington, Wj; Prive, Gg; Taylor, Jp; Sharon, M; Schuck, P; Ogden, Sk; Mittag, T (2016). Higher-Order Oligomerization Promotes Localization of Spop to Liquid Nuclear Speckles.  EMBO Journal. 35:1254-1275.  Abstract
Mayor, T; Sharon, M; Glickman, Mh (2016). Tuning the Proteasome to Brighten the End of the Journey.  American Journal of Physiology-Cell Physiology. 311:C793-C804.
Olshina, Ma; Sharon, M (2016). Mass Spectrometry: a Technique of Many Faces.  Quarterly Reviews of Biophysics. 49.  Abstract

2015

Sharon, M; Horovitz, A (2015). Probing Allosteric Mechanisms Using Native Mass Spectrometry.  Current Opinion in Structural Biology. 34:7-16.  Abstract
Rozen, S; FüZesi-Levi, Mg; Ben-Nissan, G; Mizrachi, L; Gabashvili, A; Levin, Y; Ben-Dor, S; Eisenstein, M; Sharon, M (2015). Csnap is a Stoichiometric Subunit of the Cop9 Signalosome.  Cell Reports. 13:585-598.  Abstract
Moscovitz, O ; Ben-Nissan, G ; Fainer, I ; Pollack, D ; Mizrachi,L ; Sharon, M (2015). The Parkinson's-Associated Protein DJ-1 Regulates the 20s Proteasome.  Nature Communications. 6.
Yanagida, H; Gispan, A; Kadouri, N; Rozen, S; Sharon, M; Barkai, N; Tawfik, Ds (2015). The Evolutionary Potential of Phenotypic Mutations.  Plos Genetics. 11:e1005445.  Abstract
Chorev, D; Ben-Nissan, G; Sharon, M (2015). Exposing the Subunit Diversity and Modularity of Protein Complexes by Structural Mass Spectrometry Approaches.  Proteomics.
Sinz, A; Arlt, C; Chorev, D; Sharon, M (2015). Chemical Cross-Linking and Native Mass Spectrometry: a Fruitful Combination For Structural Biology.  Protein Science. 24:1193-1209.

2014

Ben-Nissan, G; Sharon, M (2014). Regulating the 20s Proteasome Ubiquitin-Independent Degradation Pathway.  Biomolecules. 4:862-884.
Lu, Q; Yao, Q; Xu, Y; Li, L; Li, S; Liu, Y; Gao, W; Niu, M; Sharon, M; Ben-Nissan, G; Zamyatina, A; Liu, Xy; Chen, S; Shao, F (2014). An Iron-Containing Dodecameric Heptosyltransferase Family Modifies Bacterial Autotransporters in Pathogenesis.  Cell Host & Microbe. 16:351-363.  Abstract
Zinck, N; Stark, Ak; Wilson, Dj; Sharon, M (2014). An Improved Rapid Mixing Device For Time-Resolved Electrospray Mass Spectrometry Measurements.  ChemistryOpen. 3:109-114.  Abstract
Fuzesi-Levi, Mg; Ben-Nissan, G; Bianchi, E; Zhou, Hj; Deery, Mj; Lilley, Ks; Levin, Y; Sharon, M (2014). Dynamic Regulation of the Cop9 Signalosome in Response to DNA Damage.  Molecular and Cellular Biology. 34:1066-1076.  Abstract
Solomon, H; Sharon, M; Rotter, V (2014). Modulation of Alternative Splicing Contributes to Cancer Development: Focusing on P53 Isoforms, P53β and P53γ.  Cell Death and Differentiation. 21:1347-1349.
Chorev, Ds; Moscovitz, O; Geiger, B; Sharon, M (2014). Regulation of Focal Adhesion Formation by a Vinculin-Arp2/3 Hybrid Complex.  Nature Communications. 5.  Abstract

2013

Sharon, M (2013). Structural ms Pulls Its Weight.  Science. 340:1059-1060.
Freeman, S; Sharon, M; Maymon, M; Mendel, Z; Protasov, A; Aoki, T; Eskalen, A; O'Donnell, K (2013). Fusarium Euwallaceae sp. Nov.--a Symbiotic Fungus of Euwallacea sp., an Invasive Ambrosia Beetle in Israel and California.  Mycologia. 105.  Abstract
Shtenberg, G; Massad-Ivanir, N; Moscovitz, O; Engin, S; Sharon, M; Fruk, L; Segal, E (2013). Picking up the Pieces: a Generic Porous si Biosensor For Probing the Proteolytic Products of Enzymes.  Analytical Chemistry. 85:1951-1956.  Abstract
Rozen, S; Tieri, A; Ridner, G; Stark, Ak; Schmaler, T; Ben-Nissan, G; Dubiel, W; Sharon, M (2013). Exposing the Subunit Diversity Within Protein Complexes: a Mass Spectrometry Approach.  Methods. 59:270-277.  Abstract
Dyachenko, A; Gruber, R; Shimon, L; Horovitz, A; Sharon, M (2013). Allosteric Mechanisms Can be Distinguished Using Structural Mass Spectrometry.  Proceedings of the National Academy of Sciences of the United States of America. 110:7235-7239.  Abstract

2012

Eshed, I; Trattnig, S; Sharon, M; Arbel, R; Nierenberg, G; Konen, E; Yayon, A (2012). Assessment of Cartilage Repair After Chondrocyte Transplantation With a Fibrin-Hyaluronan Matrix--Correlation of Morphological MRI, Biochemical t2 Mapping and Clinical Outcome.  European Journal of Radiology. 81.
Shtenberg, G; Massad-Ivanir, N; Engin, S; Sharon, M; Fruk, L; Segal, E (2012). DNA-Directed Immobilization of Horseradish Peroxidase Onto Porous Sio2 Optical Transducers.  Nanoscale Research Letters. 7.  Abstract
Moscovitz, O; Tsvetkov, P; Hazan, N; Michaelevski, I; Keisar, H; Ben-Nissan, G; Shaul, Y; Sharon, M (2012). A Mutually Inhibitory Feedback Loop Between the 20s Proteasome and Its Regulator, Nqo1.  Molecular Cell. 47:76-86.  Abstract
Tsvetkov, P; Myers, N; Moscovitz, O; Sharon, M; Prilusky, J; Shaul, Y (2012). Thermo-Resistant Intrinsically Disordered Proteins Are Efficient 20s Proteasome Substrates.  Molecular Biosystems. 8:368-373.  Abstract

2011

Sharon, M; Robinson, Cv (2011). A Quantitative Perspective on Hydrophobic Interactions in the Gas-Phase.  Current Proteomics. 8:47-58.  Abstract
Sharon, M; Robinson, Cv (2011). Peeling Back the Layers of Complexity.  Current Opinion in Structural Biology. 21:619-621.
Sharon, M; Freeman, S; Sneh, B (2011). Assessment of Resistance Pathways Induced in Arabidopsis Thaliana by Hypovirulent Rhizoctonia Spp. Isolates.  Phytopathology. 101.  Abstract
Ben-Nissan, G; Sharon, M (2011). Capturing Protein Structural Kinetics by Mass Spectrometry.  Chemical Society Reviews. 40:3627-3637.  Abstract

2010

Michaelevski, I; Kirshenbaum, N; Sharon, M (2010). T-Wave Ion Mobility-Mass Spectrometry: Basic Experimental Procedures For Protein Complex Analysis.  Journal of Visualized Experiments : JoVE.  Abstract
Sharon, M (2010). How Far Can we go With Structural Mass Spectrometry of Protein Complexes?.  Journal of the American Society For Mass Spectrometry. 21:487-500.  Abstract
Shimon, L; Sharon, M; Horovitz, A (2010). A Method For Removing Effects of Nonspecific Binding on the Distribution of Binding Stoichiometries: Application to Mass Spectroscopy Data.  Biophysical Journal. 99:1645-1649.  Abstract
Sheard, Lb; Tan, X; Mao, Hb; Withers, J; Ben-Nissan, G; Hinds, Tr; Kobayashi, Y; Hsu, Ff; Sharon, M; Browse, J; He, Sy; Rizo, J; Howe, Ga; Zheng, N (2010). Jasmonate Perception by Inositol-Phosphate-Potentiated Coi1-Jaz co-Receptor.  Nature. 468:400-U301.  Abstract
Michaelevski, I; Eisenstein, M; Sharon, M (2010). Gas-Phase Compaction and Unfolding of Protein Structures.  Analytical Chemistry. 82:9484-9491.  Abstract
Yadid, I; Kirshenbaum, N; Sharon, M; Dym, O; Tawfik, Ds (2010). Metamorphic Proteins Mediate Evolutionary Transitions of Structure.  Proceedings of the National Academy of Sciences of the United States of America. 107:7287-7292.  Abstract
Kirshenbaum, N; Michaelevski, I; Sharon, M (2010). Analyzing Large Protein Complexes by Structural Mass Spectrometry.  Journal of Visualized Experiments : JoVE.  Abstract

2009

Andersson, F; Tryggvesson, A; Sharon, M; Diemand, A V; Classen, M; Best, C; Schmidt, R; Schelin, J; Stanne, T M; Bukau, B; Robinson, C V; Witt, S; Mogk, A; Clarke, A K (2009). Structure and Function of a Novel Type of Atp-Dependent Clp Protease.  The Journal of Biological Chemistry. 284.  Abstract
Sharon, M; Mao, H; Boeri Erba, E; Stephens, E; Zheng, N; Robinson, C V (2009). Symmetrical Modularity of the Cop9 Signalosome Complex Suggests Its Multifunctionality.  Structure (London, England : 1993). 17.  Abstract
Gazit, K; Moshonov, S; Elfakess, R; Sharon, M; Mengus, G; Davidson, I; Dikstein, R (2009). Taf4/4b.Taf12 Displays a Unique Mode of DNA Binding and is Required For Core Promoter Function of a Subset of Genes.  Journal of Biological Chemistry. 284:26286-26296.  Abstract

2008

Taverner, T; Hernandez, H; Sharon, M; Ruotolo, B T; Matak-Vinkovic, D; Devos, D; Russell, R B; Robinson, C V (2008). Subunit Architecture of Intact Protein Complexes from Mass Spectrometry and Homology Modeling.  Accounts of Chemical Research. 41.  Abstract
Esteban, O; Bernal, R A; Donohoe, M; Videler, H; Sharon, M; Robinson, C V; Stock, D (2008). Stoichiometry and Localization of the Stator Subunits e and g in Thermus Thermophilus h+-Atpase/Synthase.  The Journal of Biological Chemistry. 283.  Abstract

2007

Anglister, J; Rosen, O; Sharon, M; Tugarinov, V; Kessler, N; Levy, R (2007). NMR Structures of the Hiv-1 v3 Region Suggest a Mechanism For the Virus Phenotype Conversion.  Journal of Biomolecular Structure & Dynamics. 24:670.
Frenkiel-Krispin, D; Wolf, Sg; Albeck, S; Unger, T; Peleg, Y; Jacobovitch, J; Michael, Y; Daube, S; Sharon, M; Robinson, Cv; Svergun, Di; Fass, D; Tzfira, T; Elbaum, M (2007). Plant Transformation by Agrobacterium Tumefaciens - Modulation of Single-Stranded DNA-Vire2 Complex Assembly by Vire1.  Journal of Biological Chemistry. 282:3458-3464.  Abstract
Sharon, M; Ilag, L L; Robinson, C V (2007). Evidence For Micellar Structure in the Gas Phase.  Journal of the American Chemical Society. 129.  Abstract
Sharon, M; Witt, S; Glasmacher, E; Baumeister, W; Robinson, C V (2007). Mass Spectrometry Reveals the Missing Links in the Assembly Pathway of the Bacterial 20 s Proteasome.  The Journal of Biological Chemistry. 282.  Abstract
Tan, X; Calderon-Villalobos, Luz I A; Sharon, M; Zheng, C; Robinson, C V; Estelle, M; Zheng, N (2007). Mechanism of Auxin Perception by the Tir1 Ubiquitin Ligase.  Nature. 446.  Abstract
Sharon, M; Robinson, C V (2007). The Role of Mass Spectrometry in Structure Elucidation of Dynamic Protein Complexes.  Annual Review of Biochemistry. 76.  Abstract

2006

Sharon, M; Taverner, T; Ambroggio, X I; Deshaies, R J; Robinson, C V (2006). Structural Organization of the 19s Proteasome Lid: Insights from ms of Intact Complexes.  PLoS Biology. 4.  Abstract
Witt, S; Kwon, Y D; Sharon, M; Felderer, K; Beuttler, M; Robinson, C V; Baumeister, W; Jap, B K (2006). Proteasome Assembly Triggers a Switch Required For Active-Site Maturation.  Structure (London, England : 1993). 14.  Abstract
Sharon, M; Witt, S; Felderer, K; Rockel, B; Baumeister, W; Robinson, C V (2006). 20s Proteasomes Have the Potential to Keep Substrates in Store For Continual Degradation.  Journal of Biological Chemistry. 281.  Abstract
Rosen, O; Samson, Ao; Sharon, M; Zolla-Pazner, S; Anglister, J (2006). Hiv-1 Coreceptor Selectivity: Structural Analogy Between Hiv-1v3 Regions and Chemokine Beta-Hairpins is Not the Explanation - Response to Matters Arising.  Structure. 14:649-651.
Rosen, O; Sharon, M; Quadt-Akabayov, Sr; Anglister, J (2006). Molecular Switch For Alternative Conformations of the Hiv-1v3 Region: Implications For Phenotype Conversion.  Proceedings of the National Academy of Sciences of the United States of America. 103:13950-13955.  Abstract
Medalia, N; Sharon, M; Martinez-Arias, R; Mihalache, O; Robinson, C V; Medalia, O; Zwickl, P (2006). Functional and Structural Characterization of the Methanosarcina Mazei Proteasome and Pan Complexes.  Journal of Structural Biology. 156.  Abstract

2005

Rosen, O; Chill, J; Sharon, M; Kessler, N; Mester, B; Zolla-Pazner, S; Anglister, J (2005). Induced Fit in Hiv-Neutralizing Antibody Complexes: Evidence For Alternative Conformations of the Gp120 v3 Loop and the Molecular Basis For Broad Neutralization.  Biochemistry. 44:7250-7258.  Abstract
Sharon, M; Rosen, O; Anglister, J (2005). NMR Studies of v3 Peptide Complexes With Antibodies Suggest a Mechanism For Hiv-1 co-Receptor Selectivity.  Current Opinion in Drug Discovery & Development. 8:601-612.  Abstract

2003

Kessler, N; Zvi, A; Ji, M; Sharon, M; Rosen, O; Levy, R; Gorny, M; Zolla-Pazner, S; Anglister, J (2003). Expression, Purification, and Isotope Labeling of the fv of the Human Hiv-1 Neutralizing Antibody 447-52d For NMR Studies.  Protein Expression and Purification. 29:291-303.  Abstract
Sharon, M; Kessler, N; Levy, R; Zolla-Pazner, S; Gorlach, M; Anglister, J (2003). Alternative Conformations of Hiv-1v3 Loops Mimic Beta Hairpins in Chemokines, Suggesting a Mechanism For Coreceptor Selectivity.  Structure. 11:225-236.  Abstract

2002

Sharon, M; Gorlach, M; Levy, R; Hayek, Y; Anglister, J (2002). Expression, Purification, and Isotope Labeling of a Gp120 v3 Peptide and Production of a Fab from a Hiv-1 Neutralizing Antibody For NMR Studies.  Protein Expression and Purification. 24:374-383.  Abstract

1999

Sharon, M; Oren, Z; Shai, Y; Anglister, J (1999). 2d-NMR and Atr-Ftir Study of the Structure of a Cell-Selective Diastereomer of Melittin and Its Orientation in Phospholipids.  Biochemistry. 38:15305-15316.  Abstract