Postdoc position at the University of East Anglia

We have an exciting postdoctoral position at the research group of Dr Jesus Angulo, at the School of Pharmacy of the University of East Anglia (UEA), in Norwich (UK), funded by the Biotechnology and Biological Sciences Research Council (BBSRC).

 

Senior Research Associate in NMR Spectroscopy (Ref: RA1555)

 

https://myview.uea.ac.uk/webrecruitment/pages/vacancy.jsf?vacancyRef=RA1555

 

The closing date is 5 November 2018.

 

 

Towards understanding the glycan code: next generation structural glycobiology for accurate description of protein-glycan complexes

 

£33,199 per annum

 

We are looking for an experienced and highly motivated Senior Research Associate to join the research team headed by Dr Jesus Angulo in the School of Pharmacy, University of East Anglia.

 

The post holder will contribute to an exciting research project, funded by BBSRC, aimed at development of novel structural glycobiology tools to provide solutions to the problem of making quantitative and accurate the determination of 3D structures of biologically relevant "weak" protein-ligand complexes (e.g. specific protein-glycan interactions) from high-resolution ligand-based NMR and computational techniques. Novel powerful NMR spectroscopy protocols (DEEP-STD NMR) have already been developed in the group and will be extended further to ease the quantitative structural determination of weak biomolecular complexes. The NMR methodological advances developed during the project will be applied to deepen our understanding of the molecular bases of biologically highly relevant protein-glycan recognition processes like, for example, the distinct molecular recognition of carbohydrates and glycomimetics by sialic acid binding receptors, the molecular recognition of carbohydrates in the "glycan shield" of HIV by potent broadly neutralizing antibodies, or the molecular bases of the specific interactions of glycosyltransferases with donor and acceptor substrates.

 

The postholder will work under the supervision of Dr J Angulo and will be expected to interact with NMR community in Norwich Research Park. The successful candidate will be expected to participate in collaborations with academic and industrial partners interested in the project.

 

You will have a minimum of PhD in appropriate field in Chemistry, Physics, Pharmacy or Biological Sciences (hold a PhD or have submitted a PhD thesis prior to appointment), and be able to fulfil all essential elements of the person specification. The full time post is available from 1 December 2018 for a fixed term of 17 months.

 

https://myview.uea.ac.uk/webrecruitment/pages/vacancy.jsf?vacancyRef=RA1555

 

Dr Jesus Angulo | Senior Lecturer in NMR Spectroscopy | School of Pharmacy

1.47 CAP Building, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ

(+44 (0)1603 597155| * j.angulo@uea.ac.uk