Postdoctoral position in structural biology of membrane remodeling

A NIH-funded postdoctoral position is available immediately in the Ramachandran Lab at Case Western Reserve University (CWRU) to study the structural aspects of protein-mediated membrane remodeling during endocytic and mitochondrial membrane fission. This position involves extensive collaboration with the lab of Patrick van der Wel at the University of Pittsburgh.  The position requires a Ph.D. in biochemistry or biophysics with a focus on structural biology or membrane biophysics (NMR or ssNMR, preferably). This position will provide an excellent opportunity to learn and apply a wide array of structural and biophysical techniques to explore protein function on a model membrane surface. The Ramachandran laboratory also employs a host of cutting-edge spectroscopic approaches including FRET, fluorescence correlation spectroscopy (FCS) and fluorescence lifetime imaging (FLIM) to explore protein-protein and protein-membrane interactions in membrane remodeling and fission, both in vitro and in vivo. The Ramachandran and Van der Wel labs and the facilities at CWRU and University of Pittsburgh are equipped with state-of-the-art instrumentation for both biophysical techniques and structural biology, as well as for protein purification, characterization and membrane reconstitution.

Requirements: Applicants must be highly motivated and must have demonstrated experience (i.e. relevant publications) in protein biochemistry and structural biology. The candidate should have a strong conceptual and experimental background in biochemistry and biophysics, as well as in the mechanistic dissection of structure-function relationships in proteins; he/she should be independent, proactive, hardworking and productive; only candidates that have first-author publications (or articles in press) will be considered. Candidates must have completed their PhD at the time of appointment. Salary will commensurate with experience and will adhere to current NIH guidelines. Interested candidates should submit their CV, reprints of selected publications, three reference letters (directly from referees), and a cover letter summarizing their experience, long-term goals, and estimated start date directly to Rajesh Ramachandran at

Relevant Publications, please visit our webpage:

Ramachandran lab: 

Van der Wel lab: