Postdoctoral position at University of Louisville

The Li lab in the Department of Chemistry at University of Louisville is seeking a highly motivated postdoctoral researcher to join our lab immediately.

Our research interests focus on applying solution NMR techniques to understand the functional roles of protein conformational dynamics in the deubiquitinase family. We’re especially interested in deubiquitinases that are involved in signaling pathways implicated in cancer and autoimmune diseases. To accomplish our research goals, we complement solution NMR spectroscopy with other biophysical and biochemical techniques, such as enzymatic assays, fluorescence spectroscopy, isothermal titration calorimetry, and X-ray crystallography. We have regular access to several NMR spectrometers on campus, ranging from 500 MHz to 800 MHz. The 600 MHz and 700 MHz spectrometers are equipped with cryoprobes. Other instruments for biophysical characterization are available in the biophysics core facility located in the medical school.

Successful candidates should possess a Ph.D. in biochemistry or a related field at the start date.  Prior experience in solution or solid-state NMR spectroscopy and preparation of protein NMR samples is required. Additional experiences in NMR method development, molecular dynamics simulation and X-ray crystallography are highly desirable.

More information about our research can be found in the lab website

Interested candidates should send a letter of interest, CV and contract information for three references to Dr. Ying Li ( )