Research Associate in NMR Spectroscopy and Protein Chemistry

Applications are invited for a postdoctoral scientist to work on an exciting project focused on understanding the solution behaviour of concentrated monoclonal antibodies. The study will involve use of NMR spectroscopy (1H and 19F) and protein labelling for characterizing protein solutions and mixtures thereof. You will have a PhD (or equivalent) in NMR spectroscopy, biochemistry and/or biophysics, or in a related discipline. Experience is required in protein NMR spectroscopy and basic protein chemistry (protein purification, concentration and labelling, e.g. with paramagnetic or fluorine labels).
The project is funded by MedImmune, the global biologics research and development arm of AstraZeneca, and is part of a collaborative initiative centred on biopharmaceuticals with the Centre of Excellence in Biopharmaceuticals (COEBP, The research project will be largely based in the Manchester Institute of Biotechnology (MIB), with placements (up to 25% FTE) at MedImmune’s R&D site in Cambridge, UK. The NMR Facility in the MIB is equipped with 800, 600 and 500 MHz Bruker spectrometers, with cryoprobes. The Formulation Laboratories at MedImmune, Cambridge, house all instrumentation and facilities necessary for a modern, large biopharmaceutical company.
You will be motivated and able to work independently. You will be responsible for intellectual steer and input to the research, experimental design and organisation, data interpretation and dissemination, meeting project deadlines and co-ordination between industry and academic supervisors.
The full time post is available from 1 October onwards and will be offered on a fixed-term contract for a period of 12 months, with the possibility for renewal for further 12 months after 12-month review.
Closing date : 12/07/2016
Reference : LSX-08394
Duration : from 01/10/2016 until 30/09/2017
Salary : £30,738 per annum
Enquiries about the vacancy, shortlisting and interviews:
Dr Alexander Golovanov
To apply and to get further particulars of the job: