Genomics, Sandbox Publications

  1. Rosenzweig N., Dvir-Szternfeld R., Tsitsou-Kampeli A., Keren-Shaul H., Ben-Yehuda H., Weill-Raynal P., Cahalon L., Kertser A., Baruch K., Amit I., Weiner A. & Schwartz M. (2019). PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model.  Nature Communications. 2019 Jan , 10 .
  2. Keren-Shaul H., Kenigsberg E., Jaitin D. A., David E., Paul F., Tanay A. & Amit I. (2019). MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing.  NATURE PROTOCOLS. 2019 May , 14 (6):1841-1862.
  3. Jaitin D. A., Adlung L., Thaiss C. A., Weiner A., Li B., Descamps H., Lundgren P., Bleriot C., Liu Z., Deczkowska A., Keren-Shaul H., David E., Zmora N., Eldar S. M., Lubezky N., Shibolet O., Hill D. A., Lazar M. A., Colonna M., Ginhoux F., Shapiro H., Elinav E. & Amit I. (2019). Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.  Cell. 2019 Jun , 178 (3):686-698.e14.
  4. Deczkowska A., Keren-Shaul H., Weiner A., Colonna M., Schwartz M. & Amit I. (2018). Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.  Cell. 2018 May , 173 (5):1073-1081.
  5. Tzfadia O., Bocobza S., Defoort J., Almekias-Siegl E., Panda S., Levy M., Storme V., Rombauts S., Jaitin D. A., Keren-Shaul H., Van de Peer Y. & Aharoni A. (2018). The 'TranSeq' 3 '-end sequencing method for high-throughput transcriptomics and gene space refinement in plant genomes.  Plant Journal. 2018 Oct , 96 (1):223-232.
  6. Alyagor I., Berkun V., Keren-Shaul H., Marmor-Kollet N., David E., Mayseless O., Issman-Zecharya N., Amit I. & Schuldiner O. (2018). Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling.  Developmental Cell. 2018 Oct , 47 (1):38-+.
  7. Ledergor G., Weiner A., Zada M., Wang S., Cohen Y. C., Gatt M. E., Snir N., Magen H., Koren-Michowitz M., Herzog-Tzarfati K., Keren-Shaul H., Bornstein C., Rotkopf R., Yofe I., David E., Yellapantula V., Kay S., Salai M., Ben Yehuda D., Nagler A., Shvidel L., Orr-Urtreger A., Halpern K. B., Itzkovitz S., Landgren O., San-Miguel J., Paiva B., Keats J. J., Papaemmanuil E., Avivi I., Barbash G. I., Tanay A. & Amit I. (2018). Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma.  Nature Medicine. 2018 Dec , 24 (12):1867-+.
  8. Keren-Shaul H., Spinrad A., Weiner A., Matcovitch-Natan O., Dvir-Szternfeld R., Ulland T. K., David E., Baruch K., Lara-Astaiso D., Toth B., Itzkovitz S., Colonna M., Schwartz M. & Amit I. (2017). A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.  Cell. 2017 Jun , 169 (7):1276-+.
  9. Varol D., Mildner A., Blank T., Shemer A., Barashi N., Yona S., David E., Boura-Halfon S., Segal-Hayoun Y., Chappell-Maor L., Keren-Shaul H., Leshkowitz D., Hornstein E., Fuhrmann M., Amit I., Maggio N., Prinz M. & Jung S. (2017). Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain.  Immunity. 2017 Jun , 46 (6):1030-+.
  10. Guillaumet-Adkins A., Rodriguez-Esteban G., Mereu E., Mendez-Lago M., Jaitin D. A., Villanueva A., Vidal A., Martinez-Marti A., Felip E., Vivancos A., Keren-Shaul H., Heath S., Gut M., Amit I., Gut I. & Heyn H. (2017). Single-cell transcriptome conservation in cryopreserved cells and tissues.  GENOME BIOLOGY. 2017 Mar , 18 .
  11. Jaitin D. A., Weiner A., Yofe I., Lara Astiaso D., Keren-Shaul H., David E., Salame T. M., Tanay A., van Oudenaarden A. & Amit I. (2016). Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.  Cell. 2016 Dec , 167 (7):1883-+.
  12. Matcovitch-Natan O., Winter D. R., Giladi A., Vargas Aguilar A. S., Spinrad A., Sarrazin S., Ben-Yehuda H., David E., Zelada Gonzalez G. F., Perrin P., Keren-Shaul H., Gury M., Lara-Astaiso D., Thaiss C. A., Cohen M., Bahar Halpern H. K., Baruch K., Deczkowska A., Lorenzo Vivas V. E., Itzkovitz S., Elinav E., Sieweke M. H., Schwartz M. & Amit I. (2016). Microglia development follows a stepwise program to regulate brain homeostasis..  Science (New York, N.Y.). 2016 Jun , 353 (6301):aad8670.
  13. Gury-BenAri M., Thaiss C. A., Serafini N., Winter D. R., Giladi A., Lara Astiaso A. D., Levy M., Salame T. M., Weiner A., David E., Shapiro H., Dori-Bachash M., Pevsner-Fischer M., Lorenzo Vivas V. E., Keren-Shaul H., Paul F., Harmelin A., Eberl G., Itzkovitz S., Tanay A., Di Santo S. J. P., Elinav E. & Amit I. (2016). The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome..  Cell. 2016 Aug , 166 (5):1231-1246.e13.
  14. Kedmi M., Ben Chetrit C. N., Koerner C., Mancini M., Ben-Moshe N. B., Lauriola M., Lavi S., Biagioni F., Carvalho S., Cohen-Dvashi H., Schmitt F., Wiemann S., Blandino G. & Yarden Y. (2015). EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer.  Science Signaling. 2015 Mar , 8 (368).
  15. Cohen-Dvashi H., Ben Chetrit C. N., Russell R., Carvalho S., Lauriola M., Nisani S., Mancini M., Nataraj N., Kedmi M., Roth L., Koestler W., Zeisel A., Yitzhaky A., Zylberg J., Tarcic G., Eilam R., Wigelman Y., Will R., Lavi S., Porat Z., Wiemann S., Ricardo S., Schmitt F., Caldas C. & Yarden Y. (2015). Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression.  EMBO Molecular Medicine. 2015 Mar , 7 (3):299-314.
  16. Ben Chetrit C. N., Chetrit D., Russell R., Koerner C., Mancini M., Abdul-Hai A., Itkin T., Carvalho S., Cohen-Dvashi H., Koestler W. J., Shukla K., Lindzen M., Kedmi M., Lauriola M., Shulman Z., Barr H., Seger D., Ferraro D. A., Pareja F., Gil-Henn H., Alon R., Milanezi F., Symons M., Ben Hamo H. R., Efroni S., Schmitt F., Wiemann S., Caldas C., Ehrlich M. & Yarden Y. (2015). Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer.  Science Signaling. 2015 Jan , 8 (360).
  17. Jaitin D. A., Keren-Shaul H., Elefant N. & Amit I. (2015). Each cell counts: Hematopoiesis and immunity research in the era of single cell genomics.  Seminars in Immunology. 2015 Feb , 27 (1):67-71.
  18. Kedmi M. (2015). MicroRNAs and Growth Factors: An Alliance Propelling Tumor Progression..  Journal of Clinical Medicine. 2015, 4 (8):1578-1599.
  19. Paul F., Arkin Y., Giladi A., Jaitin D. A., Kenigsberg E., Keren-Shaul H., Winter D., Lara-Astiaso D., Gury M., Weiner A., David E., Cohen N., Lauridsen F. K. B., Haas S., Schlitzer A., Mildner A., Ginhoux F., Jung S., Trumpp A., Porse B. T., Tanay A. & Amit I. (2015). Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.  Cell. 2015 Dec , 163 (7):1663-1677.
  20. Jaitin D. A., Kenigsberg E., Keren-Shaul H., Elefant N., Paul F., Zaretsky I., Mildner A., Cohen N., Jung S., Tanay A. & Amit I. (2014). Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types.  Science. 2014 Feb , 343 (6172):776-779.