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Ronny Neumann
Home Page of Prof. Ronny Neumann

The Israel and Rebecca Sieff Professor of Organic Chemistry

Head of the Department

The Weizmann Institute of Science
76100 Rehovot, Israel
telephone: +972 (8) 934-3354 
e-mail: ronny.neumann@weizmann.ac.il


Members of the group:

Senior Research Associate:  
Alex Khenkin Ph.D. alex.khenkin@weizmann.ac.il
Postdoctoral Researchers: 
Mario De bruyn mario.de-bruyn@weizmann.ac.il
Vladimir Kogan vladimir.kogan@weizmann.ac.il
Sylvain Gatard sylvain.gatard@weizmann.ac.il
Graduate Students:  
Itzik Bar-Nahum itzik.bar-nahum@weizmann.ac.il
Adina Haimov adina.haimov@weizmann.ac.il
Galia Ma`ayan galia.maayan@weizmann.ac.il
Lena Branytska olena.branytska@weizmann.ac.il
Dorit Sloboda-Rozner dorit.sloboda@weizmann.ac.il
Maxym Vasylyev maxym.vasylyev@weizmann.ac.il
Irakliy Ebralidze irakliy.ebralidze@weizmann.ac.il
Aviad Itzcovitc aviad.itckovitc@weizmann.ac.il

 

[Neumann group picture]
Standing (L to R): Galia Ma`ayan, Sylvain Gatard, Ronny Neumann, Adina Haimov, Maxim Vasilyev, and Alex Khenkin.
Seated (L to R): Mario De bruyn, Itzik Bar-Nahum, Lena Branytska, and Dorit Sloboda-Rozner.
(Click on image to enlarge.)


Research in our Group

The "push" of modern society towards environmentally sound "green chemistry" has led to concentrated activity into the development of new catalytic methods to replace effective but ecologically unacceptable stoichiometric procedures. In this context, molecular oxygen, hydrogen peroxide, ozone and nitrous oxide as oxidants and/or oxygen donors in metal-catalyzed oxidations in the liquid phase have the future potential for becoming basic chemical reactions for the derivatization of many classes of organic substrates, especially hydrocarbons. In order to realize the potential of these oxygen donors in such oxidation reactions, there is first still required a continuing intensive effort to identify new catalysts and catalyst precursors.

In general we are investigating the preparation, characterization and use of polyoxometalates and derivatives such as transition metal substituted polyoxometalates and organometallic polyoxometalates as catalysts. These are attractive compounds for oxidation catalysis due to their high stability to strongly oxidizing conditions. Second, a key point in our research efforts is to probe the possible modes of activation of the oxidant, especially in the case of molecular oxygen. Third, we also engage in mechanistic efforts to understand reaction pathways and to identify active intermediates. Finally, the synthetic scope of our new catalytic procedures are evaluated.



Click here for list of all publications since 2000 (including DOIs) [Submit additions and corrections]

Selected publications

2005

Dendritic Phosphonates and the in situ Assembly of Polyperoxophosphotungstates: Synthesis and Catalytic Epoxidation with Hydrogen Peroxide " Maxym V. Vasylyev, Didier Astruc and Ronny Neumann, Advanced Synthesis and Catalysis, in press.

"Highly Efficient Recycling of a Sandwich Type Polyoxometalate Oxidation Catalyst using Solvent Resistent Nanofiltration. " Peter T. Witte, Sankhanilay Roy Chowdury, Johan E. ten Elshof, Dorit Sloboda-Rozner, Ronny Neumann and Paul L. Alsters, Chemical Communications, in press.

"Strategies for Oxidation Catalyzed by Polyoxometalates at the Interface of Homogeneous and Heterogeneous Catalysis." Maxym Vazylyev, Dorit Sloboda-Rozner, Adina Haimov, Galia Maayan and Ronny Neumann, Topic in Catalysis, accepted for publication.

2004

“New Heterogeneous Polyoxometalate Based Mesoporous Catalysts for Hydrogen Peroxide Mediated Oxidation Reactions" Maxym V. Vasylyev and Ronny Neumann, Journal of the American Chemical Society 2004, 126, 884-890. http://dx.doi.org/10.1021/ja036702g

"Aqueous Biphasic Oxidation: A Water Soluble Polyoxometalate Catalyst for Selective Oxidation of Various Functional Groups with Hydrogen Peroxide" Dorit Sloboda-Rozner, Peter Witte, Paul L. Alsters and Ronny Neumann, Advanced Synthesis and Catalysis, 2004, 346, 339-345. http://dx.doi.org/10.1002/adsc.200303156

"Self-Assembled Na12[WZn3(ZnW9O34)2] as an Industrially Attractive Multi-Purpose Catalyst for Oxidations with Aqueous Hydrogen Peroxide" Peter T. Witte, Paul L. Alsters, Walther Jary, Ruth Müllner, Peter Pöchlauer, Dorit Sloboda-Rozner and Ronny Neumann, Organic Process Research and Development, 2004, 8524-531. http://dx.doi.org/10.1021/op034184o

"Synthesis of Aromatic Aldehydes by Oxidative Hydroxymethylation" Olena V. Branytska and Ronny Neumann, Synlett 2004, 1575-1576. http://dx.doi.org/10.1055/s-2004-829535

"Oxidation of Alkylarenes by Nitrate Catalyzed by Polyoxophosphomolybdates: Synthetic Applications and Mechanistic Insights." Alexander M. Khenkin and Ronny Neumann, Journal of the American Chemical Society, 2004, 126, 6356-6362. http://dx.doi.org/10.1021/ja031710i

"Synthesis of Dendritic Polyoxometalate Complexes Assembled by Ionic Bonding and their Function as Recoverable and Re-usable Oxidation Catalysts." Lauriane Plault, Andreas Hauseler, Sylvain Nlate, Didier Astruc, Sylvain Gatard and Ronny Neumann, Angewandte Chemie International Edition, 2004, 43, 2924-2928. http://dx.doi.org/10.1002/anie.200453870

"Computer Generated High Valent Iron-Oxo and Manganese-Oxo Species with Polyoxometalate Ligands - How do they Compare with the Iron-Oxo Active Species of Heme Enzymes?" Samuël P. de Visser, Devesh Kumar, Ronny Neumann and Sason Shaik, Angewandte Chemie International Edition 2004, 43, 5661-5665. http://dx.doi.org/10.1002/anie.200453867

"Mild, Aqueous, Aerobic, Catalytic Oxidation of Methane to Methanol and Acetaldehyde Catalyzed by a Supported Bipyrimidinylplatinum-Polyoxometalate Hybrid Compound." Itsik Bar-Nahum, Alexander M. Khenkin and Ronny Neumann, Journal of the American Chemical Society, 2004, 126, 10236-10237. http://dx.doi.org/10.1021/ja0493547

"Alkylated Polyethyleneimine/Polyoxometalate Synzymes as Catalysts for the Oxidation of Hydrophobic Substrates in Water with Hydrogen Peroxide" Adina Haimov, Hagai Cohen and Ronny Neumann, Journal of the American Chemical Society, 2004, 126, 11762-11763. http://dx.doi.org/10.1021/ja046349u

"Synthesis, Catalytic activity in Oxidation Reactions, and Recyclability of Stable Polyoxometalate-Centered Dendrimers" Sylvain Nlate, Didier Astruc and Ronny Neumann, Advanced Synthesis and Catalysis 2004, 346, 1445-1448. http://dx.doi.org/10.1002/adsc.200404185

"Polyoxometalates as Catalysts for Oxidation with Hydrogen Peroxide and Molecular Oxygen" Ronny Neumann in Transition Metals for Fine Chemicals and Organic Synthesis Vol. 2, 2nd edition C. Bolm and M. Beller, eds. Wiley-VCH, Weinheim, 2004, 415-426.

" Liquid Phase Oxidation Reactions Catalyzed by Polyoxometalates" Ronny Neumann in Modern Oxidation Methods, J. E. Bäckvall, ed. Wiley-VCH, Weinheim, 2004, 223-251.

2003

"Activation of Nitrous Oxide and Selective Oxidation of Alcohols and Alkylarenes Catalyzed by the [PV 2Mo10O40],5- Polyoxometalate". Revital Ben-Daniel and Ronny Neumann, Angewandte Chemie International Edition, 2003, 42, 92-95 and Angewandte Chemie, 2003, 115, 96-99. http://dx.doi.org/10.1002/anie.200390062

"A Highly Chemoselective, Diastereoselective and Regioselective Epoxidation of Chiral Allylic Alcohols with Hydrogen Peroxide, Catalyzed by Sandwich-Type Polyoxometalates:   Enhancement of Reactivity and Control of Reactivity by the Hydroxy Group through Metal-Alcoholate Bonding" Waldemar Adam, Paul L. Alsters, Ronny Neumann, Chantu R. Saha-Möller, Dorit Sloboda-Rozner and Rui Zhang, Journal of Organic Chemistry, 2003, 68, 1721-1728. http://dx.doi.org/10.1021/jo0266386

"Highly Efficient Catalytic Asymmetric Epoxidation of Allylic Alcohols by an Oxovanadium-Substituted Polyoxometalate with a Regenerative TADDOL-Derived Hydroperoxide" Waldemar Adam, Paul L. Alsters, Ronny Neumann, Chantu R. Saha-Möller, Dieter Seebach and Rui Zhang, Organic Letters, 2003, 5, 725-728. http://dx.doi.org/10.1021/ol027498p

"Inorganic-Organic Hybrid Materials Based on Polyoxometalates and Organic Polyammonium Cations" Maxym Vasylyev, Ronit Popovitz-Biro, Linda J. W. Shimon and Ronny Neumann, Journal of Molecular Structure, 2003, 656, 27-35. http://dx.doi.org/10.1016/S0022-2860(03)00330-2

"Fluorinated Alcohols Enable Olefin Epoxidation by H2O2: Template Catalysis", Samuël P. de Visser, Jose Kaneti, Ronny Neumann and Sason Shaik, Journal of Organic Chemistry, 2003, 68, 2903-2912. http://dx.doi.org/10.1021/jo034087t

"Preparation and Characterization of New Ruthenium and Osmium Containing Polyoxometalates, [M(DMSO)3Mo7O24]4- (M = Ru(II), Os(II)), as Catalysts for the Aerobic Oxidation of Alcohols" Alexander M. Khenkin, Linda J. W. Shimon and Ronny Neumann, Inorganic Chemistry, 2003, 42, 3331-3339. http://dx.doi.org/10.1021/ic026003p

"Organometallic-Polyoxometalate Hybrid Compounds: MetalloSalen Compounds Modified by Keggin Type Polyoxometalates". Itsik Bar-Nahum, Hagai Cohen and Ronny Neumann, Inorganic Chemistry,, 2003, 42, 3677-3684. http://dx.doi.org/10.1021/ic034095s

"A Water Soluble and 'Self-Assembled' Polyoxometalate as a Recyclable Catalyst for Oxidation of Alcohols in Water with Hydrogen Peroxide" Dorit Sloboda-Rozner, Paul L. Alsters and Ronny Neumann, Journal of the American Chemical Society, 2003, 125, 5280-5281. http://dx.doi.org/10.1021/ja0344821

"Polyfluorinated Quaternary Ammonium Salts of Polyoxometalate Anions:  Fluorous Biphasic Oxidation Catalysis with and without Fluorous Solvents" Galia Maayan, Richard H. Fish and Ronny Neumann, Organic Letters 2003, 5, 3547-3550. http://dx.doi.org/10.1021/ol0348598

"Chiral Hydroperoxides as Oxygen Source in the Catalytic Asymmetric Epoxidation of Allylic Alcohols by Sandwich-Type Polyoxometalates: Control of Enantioselectivity through a Metal-Coordinated Template" Waldemar Adam, Paul L. Alsters, Ronny Neumann, Chantu R. Saha-Möller, Dieter Seebach, Albert K. Beck and Rui Zhang, Journal of Organic Chemistry 2003, 68, 8222-8231. http://dx.doi.org/10.1021/jo034923z

"Electrophilic Aromatic Chlorination and Haloperoxidation of Chloride Catalyzed by Polyfluorinated Alcohols: A New Manifestation of Template Catalysis" Revital Ben-Daniel, Samuël P. de Visser, Sason Shaik and Ronny Neumann, Journal of the American Chemical Society 2003, 125, 12116-12117. http://dx.doi.org/10.1021/ja0364524

"Synthesis, Characterization and Catalytic Activity of a Wilkinson Type Organometallic - Polyoxometalate Hybrid Compound" Itsik Bar-Nahum and Ronny Neumann, Chemical Communications, 2003, 2690-2691. http://dx.doi.org/10.1039/b310236j

"An Efficient, Catalytic, Aerobic, Oxidative Iodination of Arenes Using the H5PV2Mo10O40 Polyoxometalate as Catalyst" Olena V. Branytska and Ronny Neumann, Journal of Organic Chemistry 2003, 68, 9510-9512. http://dx.doi.org/10.1021/jo035271h

"Applications of Polyoxometalates in Homogeneous Catalysis" Ronny Neumann, in Polyoxometalate Molecular Science, J. J. Borras, E. Coronado, A. Müller and M. T. Pope, eds. Kluwer, 2003, 327-350.

2002

"Preferential Catalytic Hydrogenation of Aromatic Compounds versus Ketones with a Palladium Substituted Polyoxometalate as Pre-catalyst." Vladimir Kogan, Zeev Aizenshtat and Ronny Neumann, New Journal of Chemistry, 2002, 26, 272-274. http://dx.doi.org/10.1039/b110937p

"Oxygen Transfer from Sulfoxides: Oxidation of Alkylarenes Catalyzed by a Polyoxomolybdate, [PMo12O40]3-."   Alexander M. Khenkin and Ronny Neumann, Journal of the American Chemical Society, 2002, 124, 4198-4199. http://dx.doi.org/10.1021/ja0178721

"Polyethylene Glycol as a Non-Ionic Liquid Solvent for Polyoxometalate Catalyzed Aerobic Oxidation". Adina Haimov and Ronny Neumann, Chemical Communications, 2002, 876-877. http://dx.doi.org/10.1039/b200559j

"Activation of Nitrous Oxide and Selective Epoxidation of Alkenes Catalyzed by the Manganese Substituted Polyoxometalate, [MnIII2ZnW(Zn2W9O34)2]10-." Revital Ben-Daniel, Lev Weiner and Ronny Neumann, Journal of the American Chemical Society, 2002, 124, 8788-8789. http://dx.doi.org/10.1021/ja0259077

"Oxygen Transfer from Sulfoxides: Selective Oxidation of Alcohols Catalyzed by Polyoxomolybdates" Alexander M. Khenkin and Ronny Neumann, Journal of Organic Chemistry, 2002, 67, 7075-7079. http://dx.doi.org/10.1021/jo0255577

"Aerobic Oxidation of Vicinal Diols Catalyzed by a Anderson Type Polyoxometalate, [IMo6O24]5-." Alexander M. Khenkin and Ronny Neumann, Advanced Synthesis and Catalysis, 2002, 344. http://dx.doi.org/10.1002/1615-4169(200210)344:9%3C1017::AID-ADSC1017%3E3.0.CO;2-X

"Carbon-Carbon and Carbon-Nitrogen Coupling Reactions Catalyzed by Palladium Nano Particles Derived from a Palladium Substituted Keggin Type Polyoxometalate" Vladimir Kogan, Zeev Aizenshtat, Ronit Popovitz-Biro and Ronny Neumann, Organic Letters, 2002, 4, 3529-3532. http://dx.doi.org/10.1021/ol026689p

"Highly Selective Catalytic Epoxidation of Chiral Allylic Alcohols by Sandwich-Type Polyoxometalates with Hydrogen Peroxide as Oxygen Source" Waldemar Adam, Paul L. Alsters, Ronny Neumann, Chantu R. Saha-Möller, Dorit Sloboda-Rozner and Rui Zhang, Synlett, 2002, 2011-2014. http://dx.doi.org/10.1055/s-2002-35570

2001

"Aerobic Oxidations Catalyzed by Polyoxometalates". Alexander M. Khenkin, Revital  Ben-Daniel, Avi Rosenberger, Inga Vigdergauz, and Ronny Neumann in Polyoxometalate Chemistry: From Topology via Self-Assembly to Applications, Achim Müller, Michael T. Pope, eds., Kluwer, 2001, 347-362.

"Antimony-Substituted Keggin Type Polyoxomolybdates: Polar Crystals and Catalytic Oxidative Dehydrogenation of Alcohols".   Alexander M. Khenkin and Ronny Neumann, European Journal of Inorganic Chemistry, 2001, 789-794. http://dx.doi.org/10.1002/1099-0682(200103)2001:3%3C789::AID-EJIC789%3E3.0.CO;2-W

"Dendrimeric Silanes for Formation of Metallosilicates: New Heterogeneous Catalysts for the Epoxidation of Alkenes with t-Butylhydroperoxide". David Juwiler and Ronny Neumann, Catalysis Letters, 2001, 72. http://ipsapp007.lwwonline.com/content/getfile/4573/4/4/abstract.htm

"A New Non-Metal Heterogeneous Catalyst for the Activation of Hydrogen Peroxide: A Perfluorinated Ketone Attached to Silica for Oxidation of Aromatic Amines and Alkenes".  Karine Neimann and Ronny Neumann, Chemical Communications, 2001, 487-488. http://dx.doi.org/10.1039/b100421m

"New Conjugated PPV Based Composites".   Shoshi Shalom, Erez Z. Faraggi, Yair Avny, Ronny Neumann and Dan Davidov, Synthetic Metals, 2001, 119 http://dx.doi.org/10.1016/S0379-6779(00)01520-4

"Redirection of Oxidation Reactions by a Polyoxomolybdate: Oxidative Dehydrogenation Instead of Oxygenation of Alkanes with Tert-butylhydroperoxide in Acetic Acid".   Alexander M. Khenkin and Ronny Neumann, Journal of the American Chemical Society, 2001, 123, 6437-6438. http://dx.doi.org/10.1021/ja005620e

"Electron and Oxygen Transfer in Polyoxometalate, H5PV2Mo10O40, Catalyzed Oxidation of Aromatic and Alkyl Aromatic Compounds: Evidence for Aerobic Mars-van Krevelen Type Reactions in the Liquid Homogeneous Phase".  Alexander M. Khenkin, Lev Weiner, Yan Wang and Ronny Neumann, Journal of the American Chemical Society,, 2001, 123, 8531-8542. http://dx.doi.org/10.1021/ja004163z

"Selective Aerobic Oxidation of Alcohols with a Combination of a Polyoxometalate and Nitroxyl Radical as Catalysts".   Revital Ben-Daniel, Paul Alsters and Ronny Neumann, Journal of Organic Chemistry, 2001, 66, 8650-8653. http://dx.doi.org/10.1021/jo0105843

"Photo-luminescence in a conjugated polymer/glass composite film". A. Donval, D. Josse, G. Kranzelbinder, R. Hierle, E. Toussaere, J. Zyss, G. Perpelitsa, O. Levi, D. Davidov, I. Bar-Nahum, R. Neumann, Synthetic Metals, 2001, 124, 59-61. http://dx.doi.org/10.1016/S0379-6779(01)00422-2

2000

"Quinones as Co-Catalysts and Models for the Surface of Active Carbon in the Phosphovanadomolybdate Catalyzed Aerobic Oxidation of Benzylic and Allylic Alcohols:  Synthetic, Kinetic and Mechanistic Aspects".  Alexander M. Khenkin, Inga Vigdergauz and Ronny Neumann, Chemistry, A European Journal, 2000, 6, 875-882. http://www3.interscience.wiley.com/cgi-bin/abstract/70003517/ABSTRACT/

"The Nickel Substituted Quasi Wells-Dawson Type Polyfluoroxometalate, [NiII(H2O)H2F6NaW17O55]9-, as a Uniquely Active Nickel Based Catalyst for the Activation of Hydrogen Peroxide and the Epoxidation of Alkenes and Alkenols".   Revital Ben-Daniel, Alexander M. Khenkin and Ronny Neumann, Chemistry, A European Journal, 2000, 6, 3722-3728. http://dx.doi.org/10.1002/10.1002/1521-3765(20001016)6:20%3C3722::AID-CHEM3722%3E3.0.CO;2-

"Mixed Addenda Vanadium Substituted Polyfluoroxometalates:   Synthesis, Characterization and Catalytic Aerobic Oxidation".  Alexander M. Khenkin and Ronny Neumann, Inorganic Chemistry, 2000, 39, 3455-3462. http://dx.doi.org/10.1021/ic990606s

"A Photo-oxidation Mechanism for Patterning and Hologram Formation in Conjugated Polymer/Glass Composites".  Ofer Levi, Galina Perepelitsa, Dan Davidov, Shoshi Shalom, Iris Benjamin, Ronny Neumann, Aharon J. Agranat and Yair Avny, Journal of Applied Physics, 2000, 88. http://dx.doi.org/10.1063/1.373809

"Aerobic Photochemical Oxidation in Mesoporous Ti-MCM-41: Epoxidation of Alkenes and Oxidation of Sulfides ".  Alexander M. Khenkin and Ronny Neumann, Catalysis Letters, 2000, 68, 109-111. http://www.baltzer.nl/catlet/contents/2000/68-1,2.html#ctl2566

"Electrophilic Activation of Hydrogen Peroxide: Selective Oxidation Reactions in Perfluorinated Alcohol Solvents", Karine Neimann and Ronny Neumann, Organic Letters, 2000, 2, 2861-2863. http://dx.doi.org/10.1021/ol006287m

"Low Temperature Activation of Molecular Oxygen and Hydrocarbon Oxidation Catalyzed by a Vanadium Substituted Polyoxomolybdate: Evidence for a Mars-van Krevelen Type Mechanism in a Liquid Phase Homogeneous Reaction Media".  Alexander M. Khenkin and Ronny Neumann, Angewandte Chemie International Edition, 2000, 112, 4088-4090 and Angewandte Chemie, 2000, 112, 4254-4256. http://www.weizmann.ac.il/Organic_Chemistry/10.1002/1521-3773(20001117)39:22%3C4088::AID-ANIE4088%3E3.0.CO;2-#


Publications prior to 2000 [Adobe Acrobat PDF format].


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