JOB DESCRIPTION
The Research associate /Associate Scientist will report to the Associate Director in the Research and Drug Discovery group. The candidate will be responsible for designing and executing experimental systems for functional validation of novel immunomodulatory molecules discovered by Compugen, including target validation activities, research tools generation and QC, expression studies, Abs characterization, cell-based assays, and reporter assay. The candidate will be responsible for planning and conducting experiments, recording and analyzing data, presenting results to management, and writing research reports. The candidate is expected to demonstrate creative/out of the box thinking, propose original solutions to complex problems, perform hands-on experimental work and be an excellent team player.
- Generate over expression systems and knock-down/knockout cells
- Perform different biochemical assays for antibody characterization (Western blot, ELISA)
- Perform cell based functional assays
- Perform antibody based in vitro assays
- Record results in laboratory notebook, prepare written reports and oral presentations in a timely manner
- Collaborate with team members to ensure timely progress of research projects according to the pipeline prioritization
- Temporary position for maternity leave (Dec. 2020-Sep. 2021)
JOB REQUIREMENTS
- PhD in Life Sciences and 1 year of experience in the biotech industry or MSc in Life Sciences and 2 years of experience in the biotech industry
- Highly experienced in cell culture technologies – must
- Over expression systems (lentivirus, retrovirus, transfections etc.) including single clone generation and characterization, cell soring
- knock-down/knock out technologies (si/shRNA, CRISPR)
- Extensive experience in cell based in vitro assays – must
- Experience in FACS staining
- Antibody based in vitro assays
- Cell based functional assays
- Experience in molecular biology methods –an advantage
- Experience biochemical technologies – Western blot, ELISA – an advantage
- knowledgeable in monoclonal Ab Discovery – advantage
- Experience and knowledge in protein purification, QC and analytics – an advantage
- Excellent written and verbal communication skills (English)
- Ability to prioritize and manage multiple projects and activities
- Ability to work independently; proactively addresses issues and troubleshoot problems
- Excellent written and oral communication and presentation skills in English
Please submit your resume to: jobs@cgen.com