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chemistry colloquia

Monday 21 January
Dolfi and Lola Ebner Auditorium 11:00
"Molecular electronics as a playground for nanoscale thermal transport" Prof. Juan Carlos Cuevas [Info]

"Molecular electronics as a playground for nanoscale thermal transport"

Abstract With the advent of novel fabrication techniques in the 1980s and 1990s, it became possible to explore many physical phenomena at the nanoscale. Since then, a lot of progress has been done in the understanding of the electronic transport, mechanical, and optical properties of nanoscale devices. However, thermal transport in these systems has remained relatively unexplored because of the experimental difficulty to measure the flow of heat and energy at this small scale. In this talk, I will review our theoretical and experimental efforts to establish the fundamental laws that govern nanoscale thermal transport by using atomic and molecular junctions as a playground. In particular, I will discuss basic phenomena such as Joule heating and Peltier cooling in molecular junctions [1,2] and quantized thermal transport in atomic-size contacts [3]. References [1] W. Lee, K. Kim, W. Jeong, L.A. Zotti, F. Pauly, J.C. Cuevas, P. Reddy, Nature 498, 209 (2013). [2] L. Cui, R. Miao, K. Wang, D. Thompson, L.A. Zotti, J.C. Cuevas, E. Meyhofer, P. Reddy, Nature Nanotechnology 13, 122 (2018). [3] L. Cui, W. Jeong, S. Hur, M. Matt, J.C Klöckner, F. Pauly, J.C. Cuevas, E. Meyhofer, P. Reddy, Science 355, 1192 (2017). Theoretical Condensed Matter Physics Department, Universidad Autónoma de Madrid, Spain
Monday 04 February
Dolfi and Lola Ebner Auditorium 11:00
"Palladium-Catalyzed Carbon-Heteroatom Bond-Forming Reactions for the Functionalization of Molecules Big and Small" Prof. Stephen L. Buchwald [Info]

"Palladium-Catalyzed Carbon-Heteroatom Bond-Forming Reactions for the Functionalization of Molecules Big and Small"

Department of Chemistry, MIT
Monday 11 February
Camelia Botnar Building 11:00
"Bio-organic systems for Electrocatalytic CO2 recycling" Prof. Serdar Sariciftci [Info]

"Bio-organic systems for Electrocatalytic CO2 recycling"

Linz-Organic Photovoltaic Cells institute in thy Johannes Kepler University of Linz
Monday 25 February
Dolfi and Lola Ebner Auditorium 11:00
"Augmenting biology through de novo protein design" Prof. Dek Woolfson [Info]

"Augmenting biology through de novo protein design"

Protein design—i.e., the construction of entirely new protein sequences that fold into prescribed structures—has come of age: it is possible now to generate a wide variety stable protein folds from scratch using rational and/or computational approaches. A challenge for the field is to move from what have been largely in vitro exercises to protein design in living cells and, in so doing, to augment biology. This talk will illustrate what is currently possible in this nascent field using de novo -helical coiled-coil peptides as building blocks.1 Coiled coils are bundles of 2 or more  helices that wrap around each other to form rope-like structures. They are one of the dominant structures that direct natural protein-protein interactions. Our understanding of coiled coils provides a strong basis for building new proteins from the bottom up. The first part of this talk will survey this understanding,1 our design methods,2,3 and our current “toolkit” of de novo coiled coils.4-6 Next, I will describe how the toolkit can be used to direct protein-protein interactions and build complex protein assemblies in bacterial cells. First, in collaboration with the Savery lab (Bristol), we have used homo- and hetero-oligomeric coiled coils as modules in engineered and de novo transcriptional activators and repressors.7 Secondly, with the Warren (Kent) and the Verkade (Bristol) labs, we have engineered hybrids of a de novo heterodimer and a natural component of bacterial microcompartments to form a “cytoscaffold” that permeates E. coli cells.8 This can be used to support the co-localisation of functional enzymes. University of Bristol
Monday 11 March
Camelia Botnar Building 11:00
Chemistry colloquium Prof. Myongsoo Lee [Info]

Chemistry colloquium

Jilin University
Monday 18 March
Camelia Botnar Building 11:00
Chemistry colloquium Prof. Lei Jiang [Info]

Chemistry colloquium

Beihang University
Monday 15 April
Camelia Botnar Building 11:00
Chemistry Colloquium Prof. Jan Schroers [Info]

Chemistry Colloquium

Yale University