A plausible structure of the TAR-RNA complex with NeoR6
Specifically, the arginine on ring I, conjugated via the aliphatic amine of neomicyn B, is positioned in the cavity form by the bulge of TAR-RNA. The interaction of the a-amino group of the arginine with the phosphates is indicated.The structure of the TAR-RNA is based on the structure of the TAR-RNA-arginineamide complex (PDB entry 1arj).
