Abstract: A protocol for retrieving multidimensional magnetic resonance spectra and images within a single scan has been recently proposed, based on a spatial encoding of the spin interactions. The spatial selectivity of this encoding process also opens up new possibilities for compensating magnetic field inhomogeneities; not by demanding extreme uniformities from the Bo fields, but rather by compensating for their effects at an excitation and/or refocusing level. This potential is hereby discussed and demonstrated in connection with the single-scan acquisition of high-definition multidimensional images. It is shown that in combination with time-dependent gradient manipulations, the new compensation approach can be used to counteract substantial field inhomogenities at either global or local levels over relatively long periods of time. The new compensation scheme could find uses in areas where heterogeneities in magnetic fields present serious obstacles, including rapid studies in regions near tissue/air interfaces. The principles of the Bo compensation method are reviewed for one- and higher-dimensional cases, and experimentally demonstrated on a series of nD single-scan MRI experiments on simple phantoms.