Abstract: Spatial-encoding is a particular kind of selective spin manipulation that enables the acquisition of multidimensional NMR spectra within a single scan. These experiments have been shown to have general applicability in the encoding of full indirect-domain evolutions for arbitrary sequences in a single transient; the present study explores their potential towards the acquisition of 2D DOSY spectra, where the indirect dimension is meant to encode molecular displacements rather than a coherent spin evolution. We find that in their simplest form this extension shows similarities with methods previously discussed for the single-scan acquisition of this kind of traces; even if a number of advantages are also evident in the new "ultrafast" modalities. The principles underlying the operation of this new single-scan 2D DOSY approach are discussed, and its use is illustrated with some simple examples.