bplist00Ñ_WebMainResourceÕ _WebResourceData_WebResourceMIMEType^WebResourceURL_WebResourceFrameName_WebResourceTextEncodingNameO8Abstract: The combination of ex situ dynamic nuclear polarization (DNP) with nuclear magnetic resonance (NMR) leads to signal-to-noise enhancements of ca. 10,000 compared to conventional NMR. Ex situ DNP, however, is ill-suited for collecting the array of transients needed in 2D NMR spectroscopy. Spatially-encoded single-scan 2D NMR methods can circumvent this drawback, yet these "ultrafast" experiments can cover spectral ranges of only ca. 20 ppm using conventional hardware. To deal with this limitation, we discuss here new spatial/spectral encoding strategies capable of folding 13C resonances into the desired spectral windows. This new approach allows one to obtain -following a single hyperpolarization process- multiple 2D heteronuclear correlations arising from different 13C regions. In combination with ex situ DNP, these principles enable the acquisition of HMBC and HSQC 2D NMR spectra on Ã… 1 mM mixtures of natural products, characterizing with a high resolution sites spread over nearly 100 ppm bandwidths. Ytext/html_Nfile:///Users/lucio/FilesWebPage/Frydman_group(latest)/Publications/abs95.htmlPUUTF-8 (:P_v”ÐÚ+, 2