Abstract: An approach has been recently introduced for acquiring 2D NMR images in a single-scan, based on the spatial encoding of the spin interactions. This paper explores the potential of integrating this spatial encoding together with conventional temporal-encoding principles, to produce 2D single-shot images with moderate field-of-views. The resulting 'hybrid' imaging scheme is shown to be superior to traditional schemes in non-homogeneous magnetic field environments. An enhancement of previously discussed pulse sequences is also proposed, whereby distortions affecting the image along the spatially-encoded axis, are eliminated. This new variant is also characterized by a refocusing of T2* effects, leading to a restoration of high-definition imaging for regions which would otherwise be highly de-phased and thus not visible. These single-scan 2D images are characterized by improved signal-to-noise ratios and a genuine T2 contrast, albeit not free from inhomogeneity distortions. Simple post-processing algorithms relying on inhomogeneity phase maps of the imaged object, can successfully remove most of these residual distortions. Initial results suggest that this acquisition scheme has the potential to overcome strong field inhomogeneities acting over extended acquisition durations, exceeding 100 ms for a single-shot image.