Research

Research in our group focuses on the development of new techniques in nuclear magnetic resonance (NMR) and Magnetic Resonance Imaging (MRI) analysis, and on the application of these and other advanced methods to the resolution of chemical problems. Most of this work is carried out in our three laboratory-built NMR spectrometers (4.7, 7.2 and 11.8 T double- and triple-tuned instruments), which are equipped with an array of solution, solid phase and microimaging accessories.

Some of the Spectroscopy Investigations we Have Recently Conducted:

¹⁴N Overtone Spectroscopy: Principles and the Overtone Rotary Recoupling (ORR) Technique
Separate Local Field NMR under Moderately Fast MAS: Observations and Applications to Dynamics, Spectral Editing
High-Resolution NMR of Half-Integer Quadrupolar Nuclei in Solids: MQMAS
Distance Measurements in Solids: The DEAR NMR Experiment
Multidimensional Solids NMR: Correlating Isotropic and Anisotropic Interactions
Non-Cartesian Sampling: The Acquistion of J Coupling- Chemical Shift 2D NMR Spectra in a Single Scan (vintage 1994)

Some of the Chemical Studies We Have Recently Carried Out:

Solid State NMR Investigations of Diamagnetic Metals (²³Na, ²⁵Mg, ³⁹K, ⁵⁹Co, ⁸⁷Rb) Bound to Nucleotides and Macromolecular RNAs
Solid State ⁵⁹Co NMR Studies of Cobalamins and their Derivatives
Solid State ⁵⁹Co MAS NMR Studies of Hexacoordinated Porphyrins
Dynamic Director NMR Studies of Liquid Crystals
NMR Studies of Lyotropic Liquid Crystalline Polymers
Diffusion in Liquid Crystalline Phases

Some of the NMR Hardware We Have Built: (proceed at your own risk; consider us disclaimed)

Schematics for a Solids NMR Spectrometer
Schematics for a 7 mm Dynamic-Angle Spinning NMR Probehead
Schematics for a Double-Tuned Microimaging NMR Probehead