Program

BM 2019 Program

Sunday, March 17
Time	Session/Lecture info
11:30-12:00	Registration & Coffee
11:30-12:00	Registration & Coffee
12:00-14:10	Session 1: Molecular and Developmental insights into the human developing brain Chair: Grazia Mancini, Erasmus MC
12:00-12:10	Welcome comments by Weizmann and Grazia Mancini
12:10-12:40	Arnold Kreigstein, University of California Genomic insights into human brain development and evolution
12:40-13:10	Colette Dehay, University of Lyon Primate and human brain development
13:10-13:40	Wieland Huttner, MPI-CGB The evolving human brain and its development
13:40-14:10	Stefen Barakat, Erasmus MC Beyond the exome, non coding variants and brain diseases
14:10-16:00	Poster session 1 & Light lunch
14:10-16:00
16:00-19:00	Session 2: Neuronal migration, supported by ISDN Chair: Wieland Huttner, MPI-CGB
16:00-16:30	Alessandra Pierani, IMAGINE institute Life and death of Cajal-Retzius subtypes in the maturation of cortical circuits
16:30-17:00	Kazu Nakajima, Keio University Neuronal migration
17:00-17:30	Laurent Nguyen, Liege Uniersity Cell-intrinsic control of interneuron migration drives cortical morphogenesis
17:30-17:45	Coffee Break
17:45-18:15	Mercedes Paredes, University of California Human Interneuron Developmend and Cortical Malformations
18:15-18:45	Silvia Cappello, Max Planck Institute of Psychiatry Modeling Neuronal Migration Disorders with Human Cerebral Organoids
18:45-19:00	Blitz 2 minutes poster talks
19:00-21:00	Opening cocktail dinner & poster session
19:00-21:00

Monday, March 18
Time	Session/Lecture info
08:30-09:00	Registration & Coffee
08:30-09:00
09:00-12:30	Session 3: Combined approaches for MCD characterization Chair: Silvia Cappello, Max Planck Institute of Psychiatry
09:00-09:30	William Dobyns, Seattle Children's Research Institute Overview of MCD categories
09:30-10:00	Gustavo Malinger, Tel Aviv University Very early detection of MCD
10:00-10:30	Tally Lerman-Sagie, Tel Aviv University Prenatal diagnosis of structural brain anomalies
10:30-11:00	Coffee Break
11:00-11:30	Jim Barkovich, University of California Use of magnetic resonance imaging (MRI) to better understand both normal brain development and to recognize and classify genetic disorders that underlie abnormal brain development
11:30-12:00	Igor Meglinski, Oulu University Laser imaging of brain - new perspectives
12:00-12:30	Blitz 2 minutes poster session
12:30-15:00	Poster session 2 combined with lunch
12:30-15:00	Lunch and posters
15:00-18:50	Session 4: Combined approaches for MCD characterization and treatment Chair: Jim Barkovich, University of California
15:00-15:30	Karina Krajden Haratz, Wolfson Medical Center Prenatal diagnosis of malformations of cortical development associated to Midbrain- Hindbrain anomalies
15:30-16:00	Wlodzimierz Klonowski , Polish Academy of Sciences Computerized analysis of images (MRI) and biosignals (EEG) used for assisting in medical diagnosis.
16:00-16:30	Grazia Mancini, Erasmus MC The importance of multidisciplinary interaction and long term follow up in MCD gene discovery
16:30-17:00	Coffee Break
17:00-17:30	Eleonora Aronica, Academisch Medisch Centrum Focal Cortical Dysplasias (FCD): from classification to treatments
17:30-18:00	Stéphanie Baulac, Institut du Cerveau et de la Moelle Brain somatic mutations in genes of the mTOR pathway in epilepsy associated with malformations of cortical development
18:00-18:30	Ute Hehr, University of Regensburg Pre- and postnatal genetic testing for brain malformations and assessment of the gene-specific long-term course and treatment
18:30-18:40	Cristiana Pelorosso, Meyer Children's Hospital A novel double hit mechanism involving different genes of the MTOR pathway in hemimegalencephaly with intractable epilepsy
18:40-18:50	Daphne J. Smits , ErasmusMC SMPD4 loss of function mutations cause microcephaly, arthrogryposis and severe encephalopathy
19:00-21:30	Gala dinner
19:00-21:30

Tuesday, March 19
Time	Session/Lecture info
08:30-09:00	Registration & Coffee
08:30-09:00
09:00-13:00	Session 5: Models for brain diseases Chair: Nataliya DiDonato , TU Dresden
09:00-09:30	Fiona Francis, Institut du Fer a Moulin, Sorbonne University, Paris France Subcortical heterotopia and radial glial cell function
09:30-10:00	Igor Ulitsky, Weizmannn Institute of Science Long non coding RNA and neurogenesis
10:00-10:30	Carlos Cardoso, INSERM Animal Models of cortical malformations: from function to pathophysiology
10:30-11:00	Jean-Bernard Manent, INSERM Circuit-level abnormalities and epilepsy in experimental subcortical band heterotopia
11:00-11:30	Coffee Break
11:30-12:00	Jurgen Knoblich, IMBA Brain organoid models
12:00-12:30	Gaia Novarino, ST Austria Models for human brain diseases
12:30-13:00	Orly Reiner, Weizmann Institute of Science Modeling brain development with organoids on chip
13:00-14:00	Lunch & Poster session
13:00-14:00
14:00-18:10	Session 6: MCD patients and treatments Chair: Carlos Cardoso, INSERM
14:00-14:30	Nadia Bahi-Buisson, IMAGINE institute MCD related to cytoskeleton dysfunction : tubulinopathies and dyneinopathies
14:30-15:00	Richard Leventer, University of Melbourne Lesional architecture in cortical tubers and cortical dysplasia: implications for treatment
15:00-15:30	Daniela Pilz, Queen Elizabeth University Hospitla ACTB and ACTG1 genes and Baraitser-Winter syndrome.
15:30-16:00	Renzo Guerrini, University of Florence Epileptogenesis and the related clinical/neurophysiological and imaging diagnostics, including ultra high field imaging, as well as surgical treatment.
16:00-16:30	Coffee Break
16:30-17:00	Bruria Ben Zeev, Sheba Medical Center Brain malformations and vascular anomalies ? how are they connected ?
17:00-17:30	Nataliya DiDonato , TU Dresden Reverse phenotyping in patients with malformations of cortical development
17:30-18:00	Naomi Josman, University of Haifa Using Virtual Reality to evaluate everyday function and quality of life in children
18:00-18:10	Best poster award
18:10-19:00	Session 7: Imaging the developing human brain in health and disease Chair: Naomi Josman, University of Haifa
18:10-18:40	Daniela Prayer, University of Vienna Brain plasticity, lessons from fetal MRI?
18:40-19:00	Closing remarks
19:10-21:00	Concluding dinner
19:10-21:00