


| • | To expand the capabilities of high-resolution solid-state NMR using Gyrotron-enhanced methodologies |
| • | To explore the potential of liquid-state Dynamic Nuclear Polarization approaches in contemporary Structural Biology NMR research |
| • | To enhance NMR’s sensitivity by developing new fast alternatives to the acquisition of liquid-state multidimensional Bio-NMR data |
| • | To develop a new suite of experiments and of data processing algorithms, capable of bypassing Nyquist stringent sampling criteria and delivering the most efficient way of very rapidly collecting and efficiently processing hyperdimensional (~ 4-6D) solution NMR spectra of high quality and Structural Biology impact |
| • | To extend the significant achievements obtained over the last few years in terms of sensitivity-enhanced biomolecular nD-NMR in liquids, to high-resolution solid-state NMR investigations |
| • | To establish different cellular systems for in-cell NMR spectroscopy |
| • | To enhance the sensitivity of in-cell NMR experiments |
| • | To establish in-cell NMR protocols for the investigation of different biological macromolecules |
| • | To develop NMR techniques for in-cell NMR |
| • | To develop protocols for solid state in-cell NMR |
| • | To implement the innovations for the benefit of the users and to disseminate the results to the scientific community at large |