About ILANIT
Monday, February 07, 2005
16:00 - 16:30 Opening Ceremony Dan Hotel, Hall A
Opening remarks: Benjamin Geiger, Congress President
Alexander Levitzki, FISEB President
Menachem Yaari, President of the Israel Academy of Sciences & Humanities
Ruth Arnon, Vice-President of the Israel Academy of Sciences and Humanities
16:30 - 17:30 Plenary 1 Dan Hotel, Hall A
Chairperson: R. Sperling
16:30 W. Baumeister, Max Planck Institute (2)
EXPLORING THE INNER SPACE OF CELLS BY CRYOELECTRON-TOMOGRAPHY
17:30 - 18: 00 Coffee Break
18:00 - 20:30 Parallel Session A-1: Transcriptional control in health and disease Dan Hotel, Hall A
Chairpersons: R. Dikstein, H. Werner
18:00 R. Dikstein, Weizmann Institute (6)
HOW TFIID INTERACTS WITH DIVERSE CORE PROMOTERS?
18:25 R. Ashery-Padan, Tel Aviv University (6)
GENETIC DISSECTION OF PAX6 DOSAGE REQUIRMENTS IN THE DEVELOPING MOUSE EYE
18:50 Y. Bergman, Hebrew University (7)
INVOLVEMENT OF HISTONE H3 METHYLATION IN THE INACTIVATION OF THE EMBRYO-SPECIFIC OCT-3/4 GENE
19:15 H. Werner, Tel Aviv University (7)
PROTEOMIC ANALYSIS OF IGF-IR GENE TRANSCRIPTION IN CANCER CELLS
19:40 Y. Groner, Weizmann Institute (8)
MECHANISM OF TRANSCRIPTIONAL REGULATION BY RUNX3
20:05 H. Cedar, Hebrew University (8)
LATE REPLICATION TIMING - A BASIC GENE REPRESSION MECHANISM
18:00 - 20:30 Parallel Session A-2: Metabolic and genetic diseases Dan Hotel, Hall B
Chairpersons: K.B. Avraham, Y. Zick
18:00 T. Ben-Yosef, Technion (9)
THE R245X MUTATION OF PCDH15, UNDERLYING USHER SYNDROME TYPE 1 IN THE ASHKENAZI JEWISH POPULATION: EVALUATING SUPPRESSION BY AMINOGLYCOSIDE ANTIBIOTICS AS AN INTERVENTION FOR VISION LOSS
18:24 B. Kerem, Hebrew University (9)
NMD PATHWAY REGULATES THE RESPONSE OF PATIENTS TO AMINOGLYCOSIDE TREATMENT
18:48 B. Glaser, Hadassah Medical Center (10)
HYPERINSULINISM OF INFANCY, A COMPLEX GENETIC SYNDROME
19:12 A. Herschkovitz, Weizmann Institute (10)
MOLECULAR MECHANISMS UNDERLING OBESITY-INDUCED INSULIN RESISTANCE
19:27 R. Hertzano, Tel Aviv University (11)
IDENTIFICATION OF TARGET GENES OF THE POU4F3 TRANSCRIPTION FACTOR BY MICROARRAY PROFILING FROM MUTANT MICE
Monday, February 07, 2005 (continued)
19:42 H. Kanety, Sheba Medical Center (11)
NEW INSIGHTS INTO THE REGULATION OF ADIPONECTIN AND ITS RECEPTORS-ADIPOR1 AND ADIPOR2
20:06 E. Wertheimer, Tel Aviv University (12)
INSULIN - FRIEND OR FOE: A NEW OUTLOOK ON DIABETES COMPLICATIONS AND CANCER
18:00 - 20:30 Parallel Session A-3: Molecular microbiology Dan Hotel, Hall C
Chairpersons: O. Amster-Choder, E. Bibi
18:00 S. Ben-Yehuda, Hebrew University (12)
CHROMOSOME REMODELING UPON ENTRY INTO SPORULATION IN BACILLUS SUBTILIS
18:30 N.Q. Balaban, Hebrew University (13)
PHENOTYPIC VARIABILITY IN THE RESPONSE TO ANTIBIOTICS
19:00 S. Pietrokovski, Weizmann Institute (13)
NEW TYPES OF INTEIN-LIKE MICROBIAL AUTO-PROCESSING PROTEIN DOMAINS
19:30 Y. Shoham, Technion (14)
REGULATION, AND STRUCTURE-FUNCTION ANALYSIS OF XYLAN-UTILIZATION ELEMENTS IN GEOBACILLUS STEAROTHERMOPHILUS
20:00 R. Schwarz, Bar Ilan University (14)
NblC, A CYNOBACTERIAL HOMOLOGUE OF ANTI-SIGMA FACTORS IS REQUIRED FOR TRANSCRIPTION ACTIVATION DURING STARVATION
20:15 M. Itsko, Ben Gurion University (15)
SITE-DIRECTED MUTAGENESIS TO PARTIALLY RESTORE ANTI-BACTERIAL ACTIVITY OF CRYPTIC CYT1CA FROM B. THURINGIENSIS ISRAELENSIS
18:00 - 20:30 Parallel Session A-4: Exocytosis and release Herods Forum Hotel, Hall E
Chairpersons: U. Ashery, D. Atlas
18:00 D. Gitler, Leipzig University (15)
BIDIRECTIONAL CONTROL OF SYNAPTIC DEPRESSION BY SYNAPSIN ISOFORMS
18:25 O. Yizhar, Tel Aviv University (16)
SHEDDING (GREEN) LIGHT ON PRIMING AND SNARE COMPLEX REGULATION
18:50 R. Cohen, Hebrew University (16)
RECONSTITUTION OF DEPOLARIZATION-INDUCED EXOCYTOSIS IN XENOPUS LAEVIS OOCYTES
19:15 I. Nussinovitch, Hebrew University (17)
ARE VOLTAGE-GATED CALCIUM CHANNELS VOLUME-REGULATED ION CHANNELS?
19:40 B. Attali, Tel Aviv University (17)
ACTIVATION OF KCNQ2/Q3 K+ CHANNELS BY NOVEL OPENERS REVEALS A ROLE OF
M-CHANNELS IN PRESYNAPTIC INHIBITION OF QUANTAL TRANSMITTER RELEASE
20:05 Y. Altschuler, Hebrew University (18)
CLATHRIN AND CAVEOLAE INVOLVMENT IN ENDOCYTOSIS OF M1 MUSCARINIC ACETYLCHOLINE RECEPTORS IN EPITHELIAL CELLS
Monday, February 07, 2005 (continued)
18:00 - 20:30 Parallel Session A-5: Functional brain imaging Herods Forum Hotel, Hall F
Chairpersons: Y. Assaf, T. Hendler
18:00 S. Gilaie-Dotan, Weizmann Institute (18)
FUNCTIONAL IMAGING OF HUMAN HIGH ORDER VISUAL AREAS
18:30 T. Hendler, Sourasky Medical Center (19)
LARGE SCALE NEURAL SYNCHRONIZATION UNDERLIES BIASED PERCEPTION OF FEARFUL FACE: HIGH DENSITY MEG STUDY
19:00 Y. Assaf, Tel Aviv University (19)
IN-VIVO DISSECTION OF WHITE MATTER BY DIFFUSION MR IMAGING
19:30 A. Karni, University of Haifa (20)
MORE OR LESS: HOW MUCH OF THE BRAIN IS ACTIVE AFTER LEARNING A SKILL?
20:00 U. Zohary, Hebrew University (20)
WHAT HAPPENS TO THE HUMAN VISUAL CORTEX WHEN THE EYES CAN'T SEE
18:00 - 20:30 Parallel Session A-6: Nanobiology Herods Forum Hotel, Hall G
Chairpersons: M. Elbaum, U. Sivan
18:00 Y. Soen, Stanford University (21)
CELL FATE CONTROL USING ARRAYS OF MICROENVIRONMENTS
18:35 D. Seliktar, Technion (21)
NANO-STRUCTURED 3-D BIOMATERIALS FOR CELLULAR STIMULATION IN TISSUE ENGINEERING
19:05 E. Gazit, Tel Aviv University (22)
SELF-ASSEMBLY ON SHORT AROMATIC PEPTIDES: FROM AMYLOID DISEASE TO NANOTECHNOLOGY
19:35 Y. Benenson, Weizmann Institute (22)
MOLECULAR COMPUTER: "SMART DRUG" IN A TEST TUBE
20:05 A. Buxboim, Weizmann Institute (23)
ON-CHIP INTEGRATION OF CELL-FREE GENE EXPRESSION
20:30 Welcome Cocktail Dan Hotel
Tuesday, February 08, 2005
07:00 - 08:00 Early Bird 1: Advanced electron microscopy Dan Hotel, Hall A
Chairpersons: E. Shimoni, S.G. Wolf
07:00 S.G. Wolf, Weizmann Institute
MACROMOLECULAR MACHINERY IN THE CELL: HIGH RESOLUTION STRUCTURES FROM 3D TRANSMISSION EM AND IMAGE PROCESSING
07:15 E. Shimoni, Weizmann Institute
CELL AND ORGANELLE ULTRASTRUCTURE IN 3D: SAMPLE PREPARATION AND ELECTRON TOMOGRAPHY
07:30 E. Klein, Weizmann Institute
WETTING OUR APPETITE FOR HIGH RESOLUTION: STATE-OF-THE-ART BIOLOGICAL SEM
07:45 A. Chausovsky, Quantomix Ltd.
SCANNING ELECTRON MICROSCOPY OF FULLY WET SAMPLES
07:00 - 08:00 Early Bird 2: The protein folding problem: can we already read genes? Dan Hotel, Hall C
Chairperson: E. Haas
07:00 E. Haas, Bar Ilan University
IS THERE A UNIFIED MECHANISM FOR THE PROTEIN FOLDING PROCESS AND THE PROBLEM OF ALTERNATIVE FOLDING, OR WHY DO SOME PROTEINS REFOLD INTO DEATH CAUSING CONFORMATIONS? THE EXPERIMENTALIST POINT OF VIEW
07:20 G. Haran, Weizmann Institute
NEW INSIGHTS OBTAINED BY WATCHING PROTEIN MOLECULES FOLDING ONE AT A TIME
07:40 R. Unger, Bar Ilan University
THE PROTEIN FOLDING ALGORITHM IS STILL UNSOLVED, WHY? WHAT DID WE ACHIEVE AND WHAT SHOULD ACHIEVE IN ORDER TO BE ABLE TO READ GENES, THE COMPUTATIONAL BIOLOGIST POINT OF VIEW
09:00 - 10:00 Plenary 2 Dan Hotel, Hall A
Chairperson: O. Livnah
09:00 T.L. Blundell, University of Cambridge (2)
STRUCTURAL BIOLOGY AND DRUG DISCOVERY: OPPORTUNITIES AND CHALLENGES
10:00 - 10: 30 Coffee Break
10:30 - 13:00 Parallel Session B-1: Structural biology Dan Hotel, Hall A
Chairpersons: F. Frolow, O. Livnah
10:30 D. Fass, Weizmann Institute (23)
DAMAGE CONTROL IN DISULFIDE BOND FORMATION: STRUCTURE AND REGULATION OF ER THIOL OXIDASES
11:00 R. Kapon, Weizmann Institute (24)
DIELECTRIC-BASED SENSING, MANIPULATION & TOMOGRAPHY: APPLICATIONS IN BIOLOGY AND PHYSICS
11:30 M. Gurevitz, Tel Aviv University (24)
DIVERSIFICATION OF SODIUM CHANNEL MODIFIERS FROM SCORPION VENOM: COMMONALITY VS SPECIFICITY
12:00 O. Medalia, Max Planck Institute (25)
STRUCTURE AND DYNAMICS OF THE NUCLEAR PORE COMPLEX AS REVEALED BY CRYO-ELECTRON TOMOGRAPHY OF INTACT NUCLEI
12:30 N. Adir, Technion (25)
CRYSTALLOGRAPHIC ANALYSIS OF INITIAL MODES OF LIGAND BINDING IN KDO8P SYNTHASE
Tuesday, February 08, 2005 (continued)
10:30 - 13:00 Parallel Session B-2: Developmental biology Dan Hotel, Hall B
Chairpersons: Y. Kassir, G. Levkowitz
10:30 U. Abdu, Ben Gurion University (26)
THE ROLE OF SPN-F IN MICROTUBULES NETWORK ORGANIZATION DURING DROSOPHILA OOGENESIS
10:52 E. Bengal, Technion (26)
P38 MAP KINASE REGULATES THE EXPRESSION OF XMYF5 AND AFFECTS DISTINCT MYOGENIC PROGRAMS DURING XENOPUS DEVELOPMENT
11:14 E. Peles, Weizmann Institute (27)
AXON-GLIA INTERACTIONS AT THE NODE OF RANVIER
11:36 A. Schlesinger, Weizmann Institute (27)
SMALL WING PLC-GAMMA IS REQUIRED FOR ER RETENTION OF CLEAVED SPITZ DURING EYE DEVELOPMENT IN DROSOPHILA
11:51 M. Zik, Ben Gurion University (28)
CHARACTERIZING THE MOLECULAR MECHANISMS UNDERLYING FLORAL ORGAN FORMATION
12:13 A. Klar, Hebrew University (28)
THE LIM HOMEODOMAIN PROTEINS LH2A AND LH2B CONTROL THE IPSI VERSUS CONTRA-LATERAL AXONAL PROJECTION OF THE D1 INTERNEURONS
12:35 Y. Kassir, Technion (29)
A NUTRIENT REGULATED SWITCH FROM HISTONE DEACETYLATION TO ACETYLATION PROMOTES THE EXPRESSION OF EARLY MEIOSIS-SPECIFIC GENES IN BUDDING YEAST
10:30 - 13:00 Parallel Session B-3: Transport proteins and channels Dan Hotel, Hall C
Chairpersons: H. Garty, B.I. Kanner
10:30 S.J. Karlish, Weizmann Institute (29)
PURIFICATION OF Na,K-ATPase EXPRESSED IN PICHIA PASTORIS
11:00 N. Nelson, Tel Aviv University (30)
BIOCHEMISTRY AND ELECTROPHYSIOLOGY OF IMPERFECTION - SLIPS IN METAL ION TRANSPORTERS
11:30 S. Schuldiner, Hebrew University (30)
A GLIMPSE INTO THE BINDING DOMAIN OF EMRE, THE SMALLEST MULTIDRUG TRANSPORTER
12:00 E. Reuveny, Weizmann Institute (31)
G PROTEIN COULPLED K CHANNELS, MOLECULAR AND SPECTROSCOPIC ANALYSIS OF THE GATING MACHINERY
12:30 E. Bibi, Weizmann Institute (31)
PROMISCUITY IN MULTIDRUG TRANSPORT: THE MANY FACETS OF MDFA
12:45 N. Rosental, Hebrew University (32)
A NEURONAL GLUTAMATE TRANSPORTER MUTANT IMPAIRED IN SUBSTRATE TRANSLOCATION EXHIBITS ALTERED ANION CONDUCTANCE SELECTIVITY
Tuesday, February 08, 2005 (continued)
10:30 - 13:00 Parallel Session B-4: Mechanisms underlying social behavior Dan Hotel, Hall D
Chairpersons: A. Hefetz, A. Lotem
10:30 Y. Lubin, Ben Gurion University (32)
THE TRANSITION FROM OUBREEDING TO INBREEDING IN THE EVOLUTION OF SOCIALITY IN SPIDERS
11:00 G. Bloch, Hebrew University (33)
DIVISION OF LABOR AND PLASTICITY IN THE CIRCADIAN CLOCK IN THE BUMBLE BEE BOMBUS TERRESTRIS
11:30 A. Lotem, Tel Aviv University (33)
EVOLUTION OF PARENT-OFFSPRING COMMUNICATION: DECISION MAKING AND LEARNING IN A COMPLEX SOCIAL ENVIRONMENT
12:00 G. Heth, University of Haifa (34)
RETHINKING MECHANISMS FOR GENETIC RELATEDNESS ASSESSMENT IN RODENTS
12:30 A. Hefetz, Tel Aviv University (34)
EVOLUTION OF WORKER STERILITY IN HONEYBEES - REPRODUCTIVE AND PHEROMONE COMPETITION
10:30 - 13:00 Parallel Session B-5: Gene therapy Herods Forum Hotel, Hall E
Chairpersons: Z. Eshhar, N. Frenkel
10:30 C. Baum, Hannover Medical School (35)
RETROVIRAL TRANSGENESIS AND ONCOGENESIS
11:10 S. Efrat, Tel Aviv University (35)
BETA-CELL REPLACEMENT IN TYPE 1 DIABETES BY ENGINEERED TISSUE STEM CELLS
11:40 D. Haratz, Vascular Biogenics Ltd. (36)
TARGETED ANTIANGIOGENIC GENE THERAPY
12:10 C. Davis, Ben Gurion University (36)
MOLDING THE VIRUS BY CHANGING HOSTS: THE SELECTION OF VARIANT MVM TARGETING CHONDROCYTES
12:25 M. Mark-Danieli, Tel Aviv University (37)
SINGLE POINT MUTATIONS IN THE ZINC-FINGER MOTIFS OF HIV-1 NUCLEOCAPSID CAN ALTER RNA-BINDING SPECIFICITIES OF THE GAG PROTEIN AND ENHANCED PACKAGING AND INFECTIVITY
12:40 Y.S. Haviv, Hadassah Medical Center (37)
SV40 MANIFESTS GLOMERULAR TARGETING AND EMERGES AS A NOVEL KIDNEY GENE THERAPY VECTOR
10:30 - 13:00 Parallel Session B-6: Cytoskeleton and cell adhesion Herods Forum Hotel, Hall F
Chairpersons: A.D. Bershadsky, S. Ravid
10:30 S. Ravid, Hebrew University (38)
THE CROSS TALK BETWEEN THE SIGNALING AND CYTOSKELETAL SYSTEMS THAT LEAD TO DIRECTED CELL MOTILITY
10:55 S. Eden, Hebrew University (38)
THE WAVE-ASSOCIATED PROTEIN HSPC300 IS INVOLVED IN LAMELLIPODIA DYNAMICS
Tuesday, February 08, 2005 (continued)
11:20 M.M. Kozlov, Tel Aviv University (39)
PROCESSIVE CAPPING BY FORMIN SUGGESTS A FORCE-DRIVEN MECHANISM OF ACTIN POLYMERIZATION
11:45 O. Reiner, Weizmann Institute (39)
MICROTUBULES AND SIGNALING PATHWAYS IN THE DEVELOPING BRAIN
12:10 T. Volk, Weizmann Institute (40)
RECIPROCAL SIGNALING BETWEEN DROSOPHILA MIGRATING MUSCLES AND THEIR TENDONS: NEW PLAYERS ESSENTIAL FOR MUSCLE ADHESION
12:35 A. Ben-Ze'ev, Weizmann Institute (40)
PLASTICITY IN COLON CANCER INVASION: REGULATION BY NOVEL TARGET GENES OF BETA-CATENIN SIGNALING
10:30 - 13:00 Parallel Session B-7: Translational regulation Herods Forum Hotel, Hall G
Chairpersons: A. Danon, O. Elroy-Stein
10:30 O. Elroy-Stein, Tel Aviv University (41)
HEIGHTENED STRESS RESPONSE IN EIF2B-MUTATED CELLS FROM CACH/VWM LEUKODYSTROPHY PATIENTS
10:55 O. Meyuhas, Hebrew University (41)
TRANSLATIONAL CONTROL OF TOP mRNAs: THE RISE AND FALL OF A DOGMA
11:20 Y. Arava, Technion (42)
EXPLORING TRANSLATION MECHANISMS BY MAPPING RIBOSOMES ALONG THE MRNA
11:45 A. Danon, Weizmann Institute (42)
LIGHT AND REDOX SIGNALS IN CONTROL OF TRANSLATION
12:10 M. Choder, Technion (43)
SUBUNITS OF RNA POLYMERASE II ARE INVOLVED IN BOTH TRANSCRIPTION AND TRANSLATION
12:35 M. Shapira, Ben Gurion University (43)
THE MANY FACES OF RUBISCO - TRANSLATION CONTROL BY EXPOSURE OF A HIDDEN RRM
13:00 - 14: 30 Lunch
14:30 - 17:00 Parallel Session C-1: DNA replication, recombination and repair Dan Hotel, Hall A
Chairpersons: Z. Livneh, J. Shlomai
14:30 J. Shlomai, Hebrew University (44)
REDOX REGULATED RECOGNITION OF THE KINETOPLAST DNA REPLICATION ORIGIN
15:00 G. Kaufmann, Tel Aviv University (44)
PROBING CURRENT MODELS OF EUKARYAL DNA CHAIN SYNTHESIS
15:30 M. Kupiec, Tel Aviv University (45)
REPAIR OF BROKEN CHROMOSOMES AND GENOME STABILITY
16:00 Z. Livneh, Weizmann Institute (45)
HOW CAN A MUTAGENIC PROCESS PREVENT CANCER: THE ERROR-PRONE DNA REPAIR CONNECTION
16:30 Y. Salzberg, Bar Ilan University (46)
SPERMATOCYTES AND LYMPHOCYTES - THE MEIG1 CONNECTION
16:45 Y. Ziv, Tel Aviv University (46)
ATM TARGETS THE KAP-1/TIF1 BETA PROTEIN IN RESPONSE TO DNA DOUBLE STRAND BREAKS
Tuesday, February 08, 2005 (continued)
14:30 - 17:00 Parallel Session C-2: Protein degradation Dan Hotel, Hall B
Chairpersons: D. Kornitzer, M. Oren
14:30 Y. Yarden, Weizmann Institute (47)
PATHWAYS LEADING TO DEGRADATION OF ONCOGENIC RECEPTOR TYROSINE KINASES: IMPLICATIONS FOR CANCER THERAPY
14:55 M. Oren, Weizmann Institute (47)
P53, MDM2 AND BEYOND
15:20 D. Kornitzer, Technion (48)
ROLE OF THE UBIQUITIN PATHWAY IN FUNGAL MORPHOGENESIS
15:45 Y. Matiuhin, Technion (48)
RPN10 RAISES THE THRESHOLD FOR DSK2 BINDING TO THE PROTEASOME
16:10 Y. Ivantsiv, Ben Gurion University (49)
INTERACTION BETWEEN THE F-BOX PROTEIN UFO1 AND THE UBL-UBA PROTEIN DDI1 IN CELL CYCLE PROGRESSION
16:25 Y. Moshe, Technion (49)
ROLE OF POLO-LIKE KINASE IN THE DEGRADATION OF EMI1, A REGULATOR OF THE ANAPHASE PROMOTING COMPLEX/CYCLOSOME
16:40 GENERAL DISCUSSION
14:30 - 17:00 Parallel Session C-3: Pattern formation and morphogenesis Dan Hotel, Hall C
Chairperson: R. Reshef
14:30 C. Kalcheim, Hebrew University (50)
LINEAGE ANALYSIS OF SOMITE DEVELOPMENT
15:00 E. Tzahor, Weizmann Institute (50)
CARDIAC CELL LINEAGES IN VERTEBRATES EMBRYOS
15:30 B. Shilo, Weizmann Institute (51)
THRESHOLD RESPONSES TO MORPHOGEN GRDIENTS BY ZERO-ORDER ULTRASENSITIVITY
16:00 G. Shemer, Technion (51)
TO FUSE OR NOT TO FUSE: A FUNDAMENTAL QUESTION
16:30 J.K. Yisraeli, Hebrew University (52)
VICKZ PROTEINS ARE A COMPONENT OF AN "RNA OPERON"
14:30 - 17:00 Parallel Session C-4: Biological clocks Dan Hotel, Hall D
Chairpersons: Y. Yarom, N. Zisapel
14:30 Y. Yarom, Hebrew University (52)
GABA, CHLORIDE AND CIRCADIAN RHYTHM
15:00 Y. Gothilf, Tel Aviv University (53)
FUNCTIONAL DEVELOPMENT OF THE PINEAL GLAND IN ZEBRAFISH
15:30 R. Green, Hebrew University (53)
REGULATION OF THE ARABIDOPSIS CIRCADIAN SYSTEM
16:00 T. Gorfine, Tel Aviv University (54)
EFFECTS OF MELATONIN ON BRAIN ACTIVITY: A BRAIN IMAGING STUDY
16:30 O. Weinreb, Technion (54)
MELATONIN INDUCED GENE EXPRESSION; COMPARISON WITH OTHER ANTIOXIDANTS
16:45 Y. Shemesh, Hebrew University (55)
SOCIAL MODULATION OF BEHAVIORAL AND MOLECULAR CIRCADIAN RHYTHMS IN HONEYBEES
14:30 - 17:00 Parallel Session C-5: Clinical applications of gene therapy Herods Forum Hotel, Hall E
Chairpersons: E. Galun, A.Oppenheim
14:30 H. Haim, Hebrew University (55)
ANALYSIS OF THE INITIAL STAGES OF VIRAL INFECTION BY MAGNETICALLY-CONTROLLED LENTIVIRAL PARTICLES
14:50 M. Flugelman, Lady Davis Carmel Medical Center (56)
THERAPEUTIC ANGIOGENESIS: CELL AND GENE THERAPY INTEGRATED APPROACH
15:10 E. Galun, Hadassah Medical Center (56)
HUMAN ERYTHROPOIETIN GENE THERAPY FOR PATIENTS WITH CHRONIC RENAL FAILURE
15:30 D. Friedmann-Morvinski, Weizmann Institute (57)
REDIRECTING LYMPHOCYTES TO BREAST TUMOR USING CHIMERIC RECEPTORS WITH ANTIBODY SPECIFICITY
15:55 G. Pelled, Hebrew University (57)
IN VIVO ELECTROPORATION OF HUMAN MESENCHYMAL STEM CELLS AS A PLATFORM FOR BONE REGENERATION
16:20 P. Ohana, Hebrew University (58)
PATIENT ORIENTED DNA BASED THERAPY OF BLADDER CANCER FROM THE BENCH TO THE PATIENT
16:45 B. Haedrich, Qiagen GmbH (324)
SIRNA DESIGN AND SYNTHESES - NEW DEVELOPMENTS FOR OPTIMAL RNAI EXPERIMENTS
14:30 - 17:00 Parallel Session C-6: From functional genomics to metabolic engineering
Chairperson: S. Wolf Herods Forum Hotel, Hall F
14:30 S. Wolf, Hebrew University
INTRODUCTION
14:40 M. Stitt, Max Planck Institute (58)
GENOMICS ANALYSIS OF CARBON-NITROGEN INTERACTIONS IN ARABIDOPSIS
15:10 A.A. Schaffer, Volcani Center (59)
SUGAR ACCUMULATION IN FLESHY FRUIT: TOMATOES AND MELONS
15:30 D. Zamir, Hebrew University (59)
RE-DOMESTICATION OF WILD TOMATO SPECIES
15:50 E. Lewinsohn, Newe Ya'ar Research Center (60)
FUNCTIONAL GENOMICS TO IDENTIFY GENES AFFECTING THE AROMA OF MELONS AND WATERMELONS
16:10 A. Vainstein, Hebrew University (60)
WHAT'S IN THE SMELL? CROSS-TALK WITHIN AND BETWEEN PATHWAYS FOR FLORAL SCENT AND COLOR
16:30 J. Hirschberg, Hebrew University (61)
FROM MUTATIONAL ANALYSIS TO METABOLIC REGULATION OF THE CAROTENOID BIOSYNTHESIS PATHWAY
16:50 GENERAL DISCUSSION
Tuesday, February 08, 2005 (continued)
14:30 - 17:00 Parallel Session C-7: Conservation biology Herods Forum Hotel, Hall G
Chairpersons: Y. Carmel, D. Saltz
14:30 S. Kark, Hebrew University (61)
TRANSITIONAL ENVIRONMENTS: CORES OR PERIPHERIES OF BIODIVERSITY?
15:00 Y. Shkedy, Israel Nature and Parks Authority (62)
IDENTIFYING NATURAL AREAS IMPORTANT FOR CONSERVATION: INTEGRATION OF THREE APPROACHES
15:30 G. Peer, UFZ-Centre for Environmental Research Leipzig-Halle (62)
LANDSCAPE CONNECTIVITY IN A COMPLEX WORLD: TACKLING MULTIPLE CHALLENGES
16:00 D. Hawlena, Ben Gurion University (63)
THE EFFECTS OF ANTHROPOGENIC CHANGES IN LANDSCAPE PHYSIOGNOMY ON A DESERT LIZARD ASSEMBLAGE
16:30 K. Schneider, Hebrew University (63)
THE POTENTIAL EFFECTS OF ATMOSPHERIC CO2 AND TEMPERATURE INCREASE ON THE PHYSIOLOGY OF HERMTYPIC CORALS
16:45 GENERAL DISCUSSION
14:30 - 17:00 Parallel Session C-8: Biological networks Herods Palace Hotel, Hall H
Chairpersons: N. Barkai, E. Braun
14:30 N. Brenner, Technion (64)
GENE RECRUITMENT AND ADPATATION OF GENE REGULATION
14:55 S. Marom, Technion (64)
LESSONS FROM EXPERIMENTAL ANALYSES OF LARGE RANDOM NEURONAL NETWORKS
15:20 R. Bar-Ziv, Weizmann Institute (65)
CELL-FREE GENETIC NETWORKS
15:45 I. Simon, Hebrew University (65)
GENOME-WIDE ANALYSIS OF CANCER RELATED DNA HYPERMETHYLATION
16:10 E. Ruppin, Tel Aviv University (66)
DOWN AND UNDER: GENETIC ROBUSTNESS IN THE YEAST METABOLIC NETWORK
16:35 N. Barkai, Weizmann Institute (66)
ROBUSTNESS IS SPACE AND TIME
17:00 - 20:00 Poster Session A Herods Forum Parking Lot
18:00 - 19:00 Societies Business Meeting Dan Hotel, Hall A
19:00 - 20:00 Annual Business Meeting of the Israel Society for Biochemistry
and Molecular Biology (ISBMB) Herods Forum Hotel, Hall F
20:00 - 22:00 Science and Society Session 1 Dan Hotel, Hall A
Chairperson: Tamar Dayan
20:00 Y. Loya, Tel Aviv University
THE CORAL REEFS OF EILAT - PAST, PRESENT AND FUTURE
20:40 J. Jackson, University of California at San Diego
WHAT WILL CORAL REEFS BE LIKE IN 2025?
21:20 S. Al-Moghrabi, Aqaba Marine Science Station
THE CORAL REEFS OF AQABA
Wednesday, February 09, 2005
07:00 - 08:00 Early Bird 3: Advanced light microscopy Dan Hotel, Hall A
Chairperson: M.E. Spira
07:00 B. Geiger, Weizmann Institute
MULTIDIMENSIONAL MICROSCOPY
07:20 M.E. Spira, Hebrew University
REAL TIME IMAGING OF SUBCELLULAR PHYSIOLOGICAL PROCESSES
07:40 U. Ashery, Tel Aviv University (124)
TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY: APPLICATION TO CELL BIOLOGY
09:00 - 10:00 Plenary 3 Dan Hotel, Hall A
Chairperson: B. Geiger
09:00 D. Louvard, Institut Curie (3)
DEVELOPMENT AND APPLICATIONS OF MURINE MODELS OF SPONTANEOUS INTESTINAL TUMORS FOR THE DEVELOPMENT OF NEW THERAPEUTIC APPROACHES
10:00 - 10:30 Coffee Break
10:30 - 13:00 Parallel Session D-1: Programmed cell death Dan Hotel, Hall A
Chairpersons: A. Barzilai, A. Kimchi
10:30 A. Kimchi, Weizmann Institute (67)
THE DAP-KINASE FAMILY OF 'DEATH KINASES'- STRUCTURE/FUNCTION AND CROSS INTERACTIONS BETWEEN MEMBERS
10:55 D. Wallach, Weizmann Institute (67)
CYTOKINE REGULATION OF CASPASE-8 APOPTOTIC AND NON-APOPTOTIC FUNCTIONS
11:20 R. Stein, Tel Aviv University (68)
THE ROLE OF BCL-2 FAMILY IN APOPTOSIS
11:45 A. Gross, Weizmann Institute (68)
THE MECHANISIMS OF ACTION OF PRO-APOPTOTIC BID
12:10 H. Engelberg-Kulka, Hebrew University (69)
TOXIN-ANTITOXIN SYSTEMS AND PROGRAMMED CELL DEATH IN BACTERIA
12:35 A. Barzilai, Tel Aviv University (69)
CELLULAR AND MOLECULAR MECHANISMS UNDERLYING OPTIC NERVE DEGENERATION FOLLOWING ACUTE NERVE INJURY
10:30 - 13:00 Parallel Session D-2: Stem cells Dan Hotel, Hall B
Chairpersons: D. Benayahu, D. Zipori
10:30 B.E. Reubinoff, Hadassah Medical Center (70)
HUMAN EMBRYONIC STEM CELLS - A POTENTIAL PLATFORM FOR NEURONAL REPAIR
11:00 N. Benvenisty, Hebrew University (70)
GENETIC ANALYSIS OF HUMAN EMBRYONIC STEM CELLS
11:30 Y. Reisner, Weizmann Institute (71)
EMBRYONIC TISSUE SPECIFIC STEM CELLS AS A NEW SOURCE FOR ORGAN TRANSPLANTATION
12:00 T. Lapidot, Weizmann Institute (71)
MECHANISM OF HUMAN STEM CELL HOMING AND REPOPULATION IN TRANSPLANTED NOD/SCID MICE
Wednesday, February 09, 2005 (continued)
12:30 D. Benayahu, Tel Aviv University (72)
MESENCHYMAL STEM CELLS DIFFERENTIATION AND SIGNATURE
10:30 - 13:00 Parallel Session D-3: Stress responses Dan Hotel, Hall C
Chairpersons: D. Engelberg, M. Shapira
10:30 S. Altuvia, Hebrew University (72)
SMALL RNAS OF STRESS RESPONSES
11:00 A. Horovitz, Weizmann Institute (73)
ALLOSTERY IN CHAPERONINS: GROEL VS. CCT
11:30 D. Zilberstein, Technion (73)
STRESS-INDUCED DIFFERENTIATION OF LEISHMANIA: ANALYSIS OF SIGNAL PERCEPTION AND RESPONSE
12:00 R. Kaempfer, Hebrew University (74)
RNA SENSORS OF STRESS SIGNALING
12:30 M.B. Toledano, DBJC-Commisariat a l' Engergie Atomique (74)
H2O2 SIGNALING BY CYSTEINE RESIDUE MODIFICATIONS
10:30 - 13:00 Parallel Session D-4: Oxidative stress and redox involvement in biological systems
Chairperson: S. Grossman Dan Hotel, Hall D
10:30 R. Kohen, Hebrew University (75)
THE ANTIOXIDANT PARADOX: TOWARDS BETTER UNDERSTANDING OF OXIDATIVE STRESS, ANTIOXIDANT DEFENSE MECHANISM AND BIOLOGICAL REDUCING POWER
11:00 O. Tirosh, Hebrew University (75)
SELENIUM: MOLECULAR MECHANISMS FOR REDOX REGULATED CELL-DEATH AND ANTI- INFLAMMATORY ACTIVITIES
11:30 D. Atlas, Hebrew University (76)
ANALYSIS OF GENE EXPRESSION IN MOG-INDUCED EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS AFTER TREATMENT WITH A NOVEL BRAIN-PENETRATING ANTIOXIDANT
12:00 A.Z. Reznick, Technion (76)
THE INVOLVEMENT OF EXTRACELLULAR AND INTRACELLULAR PEROXYNITRITE IN THE ACTIVATION OF NF-kB IN L8 MYOBLASTS
12:30 J. Kanner, ARO - Volcani Center (77)
LIPID PEROXIDATION INHIBITED BY POLYPHENOLS IN SIMULATED AND HUMAN GASTRIC FLUID: IMPLICATION ON HEALTH
10:30 - 13:00 Parallel Session D-5: Membrane trafficking and protein sorting Herods Forum Hotel, Hall E
Chairpersons: D. Cassel, Z. Elazar
10:30 Z. Elazar, Weizmann Institute (77)
AUTOPHAGY IN LIVING MAMMALIAN CELLS
11:00 J.E. Gerst, Weizmann Institute (78)
ROLE OF mRNA TRAFFICKING IN POLARITY ESTABLISHMENT AND EXOCYTOSIS IN YEAST
11:30 G.Z. Lederkremer, Tel Aviv University (78)
UNIQUE SORTING AND SUGAR CHAIN PROCESSING IN GLYCOPROTEIN ER QUALITY CONTROL
Wednesday, February 09, 2005 (continued)
12:00 S. Bar-Nun, Tel Aviv University (79)
RETENTION AND DEGRADATION OF PROTEINS IN THE SECRETORY PATHWAY: FROM THE IMMUNE SYSTEM TO YEAST
12:30 Y.I. Henis, Tel Aviv University (79)
REGULATION OF H-RAS MEMBRANE ASSOCIATION BY THREE SEPARABLE DOMAINS: GTP-DEPENDENT REGUALTION OF MEMBRANE AFFINITY AND OF SEGREGATION BETWEEN RAFT AND NON-RAFT SITES
10:30 - 13:00 Parallel Session D-6: Cross-talk in environmental and biotic stress Herods Forum Hotel, Hall F
Chairperson: A. Altman
10:30 A. Altman, Hebrew University
INTRODUCTORY REMARKS
10:40 D. Scheel, Leibniz Institute of Plant Biotechnology (80)
NON-HOST RESISTANCE OF PLANTS AGAINST PHYTOPHTHORA
11:10 R. Mittler, University of Nevada (80)
THE REACTIVE OXYGEN GENE NETWORK OF PLANTS
11:30 R. Fluhr, Weizmann Institute (81)
PROTEASES AND THEIR COGNATE SERPIN INHIBITORS REGULATE PLANT STRESS RESPONSE
11:50 D. Bartels, Bonn University (81)
MOLECULAR ANALYSIS OF DESICCATION TOLERANCE: ISOLATION OF GENES CONFERRING STRESS TOLERANCE
12:20 O. Shaul, Bar Ilan University (82)
MULTILEVEL REGULATION OF THE ATMHX GENE ENCODING A VACUOLAR METAL TRANSPORTER
12:40 A. Zamir, Weizmann Institute (82)
THE SIGNIFICANCE OF MOLECULAR ADAPTATION IN SALT TOLERANCE: LESSONS LEARNT FROM EXTRACELLULAR PROTEINS OF THE HALOTOLERANT GREEN ALGA DUNALIELLA SALINA
10:30 - 13:00 Parallel Session D-7: Host-pathogen interaction Herods Forum Hotel, Hall G
Chairpersons: E. Hanski, D. Mirelman
10:30 A. Shafferman, IIBR (83)
GENOMIC AND PROTEOMIC ANALYSES OF BACILLUS ANTHRACIS VIRULENCE RELATED GENES AS POTENTIAL VACCINE CANDIDATES
11:00 E. Rosenberg, Tel Aviv University (83)
BACTERIAL BLEACHNIG OF CORALS
11:30 D. Mirelman, Weizmann Institute (84)
EPIGENETIC SILENCING (TGS) OF AN AMOEBAPORE GENE IN ENTAMOEBA HISTOLYTICA
12:00 I. Rosenshine, Hebrew University (84)
THE GROUP-4-CAPSULE OF E. COLI
12:30 E. Hanski, Hebrew University (85)
POSITIVE, NEGATIVE AND QUORUM SENSING-MEDIATED REGULATION OF GROUP A STREPTOCOCCUS VIRULENCE
13:00 - 14: 30 Lunch
14:30 - 17:00 Parallel Session E-1: Molecular genetics of cancer Dan Hotel, Hall A
Chairpersons: Y. Haupt, Y. Shiloh
14:30 V. Rotter, Weizmann Institute (85)
AMPLIFICATION1 OF p53 INDUCED "SIGNATURE GENES" IN CELLS TRANSFORMED IN VITRO
14:55 D. Ginsberg, Weizmann Institute (86)
THE E2F1-P53 CONNECTION: MANY WAYS TO COOPERATE IN APOPTOSIS
15:20 Y. Shiloh, Tel Aviv University (86)
ATM: MOBILIZING THE CELLULAR RESPONSE TO DOUBLE STRAND BREAKS IN THE DNA
15:45 Y. Shaul, Weizmann Institute (87)
THE MECHANISM OF p53 AND p73 UBIQUITIN-INDEPENDENT DEGRADATION
16:10 Y. Haupt, Hebrew University (87)
ACTIVATION OF p53 BY PIN1 IN RESPONSE TO DNA DAMAGE IS MEDIATED BY CHK2
16:35 G. Rechavi, Sheba Medical Center (88)
BCL6 IS REGULATED BY P53 THROUGH A DNA BINDING SITE IN A REGION COMMONLY ALTERED IN LYMPHOMA
14:30 - 17:00 Parallel Session E-2: Biotechnology Dan Hotel, Hall B
Chairpersons: S. Arad, Y. Reiter
14:30 A. Schwartz, Teva Pharmaceutical Industries Ltd. (88)
PHARMACOLOGY AND BEYOND
15:00 A. Ben Amoz, National Institute of Oceanographic (90)
PRODUCTION OF PHYTOENE AND PHYTOFLUENE, COLORLESS CAROTENOIDS AND THEIR NUTRITIONAL AND CLINICAL EVALUATION
15:30 S. Dagan, XTL Biopharmaceuticals Ltd. (89)
HUMAN MONOCLONAL ANTIBODIES FOR TREATMENT AND PREVENTION OF VIRAL HEPATITIS
16:00 P. Fishman, Can-Fite BioPharma (89)
THE A3 ADENOSINE RECEPTOR (A3AR) AS A TARGET TO COMBAT CANCER AND INFLAMMATION
16:30 F. Grynspan, Gamida-Cell Ltd (90)
EX VIVO EXPANSION OF STEM CELLS AS AN ANSWER TO THE NEW BIOTECHNOLOGY CHALLENGES
14:30 - 17:00 Parallel Session E-3: The RNA world Dan Hotel, Hall C
Chairpersons: S. Michaeli-Goldberg, G. Schuster
Sponsored by Bio-Rad Laboratories
14:30 R. Sperling, Hebrew University (91)
THE SUPRASPLICEOSOME - A MACHINE FOR MAKING FUNCTIONAL MRNA
15:00 N. Jarrous, Hebrew University (91)
A LINK BETWEEN TRANSCRIPTION AND EARLY PROCESSING MACHINES OF TRNA
15:30 E.Y. Levanon, Tel Aviv University, Sheba Medical Center (92)
NOVEL EVOLUTIONARY CONSERVED TARGETS OF ADENOSINE TO INOSINE RNA EDITING
16:00 Y. Tzfati, Hebrew University (92)
A SECONDARY STRUCTURE MODEL FOR BUDDING YEAST TELOMERASE RNA
Wednesday, February 09, 2005 (continued)
16:30 S. Michaeli-Goldberg, Bar Ilan University (93)
TRANS-SPLICING IN TRYPANOSOMES REQUIRES A GUIDE RNA-THE COMPLEX BIOGENESIS OF SL RNA
16:45 G. Schuster, Technion (93)
RNA POLYADENYLATION IN ARCHAEA AND HUMAN MITOCHONDRIA; DIFFERENT TAILS TELL DIFFERENT TALES
14:30 - 17:00 Parallel Session E-4: Mechanisms and interactions Dan Hotel, Hall D
Chairpersons: Y. Ayal, I. Izhaki
14:30 Y. Ayal, Ben Gurion University (94)
DESERT COMMUNITY STRUCTURE - A HIGH DIVERSITY COMMUNITY IS MAINTAINED IN AN UNPRODUCTIVE ENVIRONMENT
15:00 A. Genin, The Interuniversity Institute for Marine Sciences (94)
FLOW EFFECTS IN THE CORAL REEF COMMUNITY
15:30 Y. Steinberger, Bar Ilan University (95)
DESERT SOIL BIOTA COMMUNITY: DIVERSITY AND DYNAMICS
16:00 U. Shanas, University of Haifa (95)
IMPACT OF HUMAN CULTURE ON COMMUNITY STRUCTURE AND BIODIVERSITY ALONG THE ISRAELI-JORDANIAN BORDER
16:30 Y. Cohen, Hebrew University (96)
COMMUNITY STRUCTURE OF HETEROTROPHIC PICOPLANKTON AS EARLY WARNING SIGNALS FOR MARINE EUTRIFICATION
14:30 - 17:00 Parallel Session E-5: Neurodegeneration and neuroprotection Herods Forum Hotel, Hall E
Chairpersons: S. Rotshenker, M.B.H. Youdim
14:30 S. Rotshenker, Hebrew University (96)
MICROGLIA ACTIVATION IN INJURY AND DISEASE IN THE CNS
15:00 E. Yavin, Weizmann Institute (97)
ANTI-APOPTOTIC AND PRO-APOPTOTIC FEATURES OF AMYLOID BETA PEPTIDE AB1-40 ACTION
15:30 E. Shohami, Hebrew University (97)
TARGETING INTRACELLULAR PATHWAYS AS NOVEL NEUROPROTECTIVE THERAPEUTIC APPROACH TO BRAIN INJURY
16:00 S. Mandel, Technion (98)
CONVERGENCE OF FAMILIAL AND IDIOPATHIC PARKINSON'S DISEASE DOPAMINERGIC NEURON DEGENERATION INVOLVING FAILURE OF THE UBIQUITIN-PROTEASOME SYSTEM TO ADEQUATELY REMOVE ABNORMAL PROTEIN
16:30 S. Erlich, Tel Aviv University (98)
CLOSED HEAD INJURY INDUCES UPREGULATION OF BECLIN 1 AT THE SITE OF INJURY
16:45 R. Beery, Sheba Medical Center (99)
NON PEPTIDE MOLECULES AS NEUROPROTECTIVE DRUGS
Wednesday, February 09, 2005 (continued)
14:30 - 17:00 Parallel Session E-6: Plant-pathogen/symbiont interactions Herods Forum Hotel, Hall F
Chairperson: Y. Hadar
14:30 R. Kahmann, Max Planck Institute (99)
USTILAGO MAYDIS: NEW INSIGHTS INTO THE EARLY INFECTION PHASE
15:00 Y. Kapulnik, Volcani Center (100)
ROOT EXUDATE OF PMI TOMATO MUTANTS REDUCES THE PROLIFERATION AND BRANCHING ACTIVITY OF ARBUSCULAR MYCORRHIZAL FUNGI
15:20 Y. Okon, Hebrew University, Faculty of Agriculture (100)
AZOSPIRILLUM FEATURES (POLYHYDROXYALKANOATES AND EXOPOLYSACCHARIDE) FOR RHIZOSPHERE COMPETENCE
15:40 P. Tudzynski, Westfaelische Wilhelms University (101)
THE ROLE OF ROS IN BIOTROPHIC VS. NECROTROPHIC PLANT-FUNGUS INTERACTIONS
16:10 A. Avni, Tel Aviv University (101)
A CYSTEINE PROTEASE MOONLIGHTS AS A REGULATOR OF ETHYLENE BIOSYNTHESIS
16:30 P. Schulze-Lefert, Max Planck Institute (102)
INDUCED CELL POLARITY IN PLANT-FUNGUS INTERACTIONS
14:30 - 17:00 Parallel Session E-7: Proteomics and structural bioinformatics Herods Forum Hotel, Hall G
Chairpersons: A. Admon, R. Unger
14:30 A. Admon, Technion (102)
THE PROTEOME, THE DEGRADOME AND THE MHC PEPTIDOME
14:55 G. Schreiber, Weizmann Institute (103)
3D STRUCTURE/FUNCTION STUDIES OF PROTEIN COMPLEXES AT THE ISRAEL STRUCTURAL PROTEOMICS CENTER (ISPC)
15:20 N. Ben-Tal, Tel Aviv University (103)
A C-ALPHA MODEL FOR THE TRANSMEMBRANE ALPHA-HELICES OF
GAP-JUNCTION INTERCELLULAR CHANNELS
15:45 I.T. Arkin, Hebrew University (104)
CENTRAL THEMES AND IRREGULARITIES IN MEMBRANE PROTEINS
16:10 H.J. Wolfson, Tel Aviv University (104)
PROTEIN BINDING SITE DETECTION
16:35 T. Hyman, Hebrew University (105)
DEVELOPMENT OF A NOVEL HIGH THROUGHPUT SCREENING TECHNOLOGY FOR THE SUBCELLULAR LOCALIZATION OF PROTEINS USING GFP
16:50 GENERAL DISCUSSION
14:30 - 17:00 Parallel Session E-8: Adaptation to extreme environments Herods Palace Hotel, Hall H
Chairpersons: D. Bar-Zvi, A. Oren
14:30 D. Bar-Zvi, Ben Gurion University (105)
SALT TOLERANCE IN PLANTS: THE ASR1 CASE
15:00 B.J. Vinocur, Hebrew University, Faculty of Agriculture (106)
THELLUNGIELLA HALOPHILLA AND POPULUS EUPHRATICA: TWO NEW MODEL SPECIES TO UNDERSTAND PLANT SALT STRESS TOLERANCE
15:15 U. Pick, Weizmann Institute (106)
ADAPTATION OF THE HALOTOLERANT ALGA DUNALIELLA TO IRON DEPRIVATION
Wednesday, February 09, 2005 (continued)
15:45 A. Oren, Hebrew University (107)
THE BIOLOGY OF SALINIBACTER, AN EXTREMELY HALOPHILIC MEMBER OF THE DOMAIN BACTERIA
16:15 M. Yonesko, Hebrew University (107)
WHEN E. COLI GOES TO THE BEACH: EXOPOLYSACCHARIDES SYNTHESIS IN RESPONSE TO OSMOTIC SHOCK
16:30 A. Minsky, Weizmann Institute (108)
SURVIVAL IN RADIOACTIVE ENVIRONMENTS
17:00 - 17: 30 Coffee Break
17:30 - 18:30 Special Plenary Session: Nobel 2004 Dan Hotel, Hall A
Chairperson: M. Sela
17:30 A. Hershko, Technion (3)
THE UBIQUITIN SYSTEM AND SOME OF ITS ROLES IN CELL CYCLE CONTROL
18:30 - 21:30 Poster Session B Herods Forum Parking Lot
20:00 - 22:30 Memorial Session: Following the footsteps of Prof. Jeff Schell Dan Hotel, Hall C
Chairperson: Y. Birk
20:00 Y. Birk, Hebrew University
INTRODUCTION
20:10 L. Willmitzer, Max Planck Institute (108)
INTEGRATION OF METABOLIC AND TRANSCRIPT PROFILING DATA - STEPS TOWARDS NETWORK ESTABLISHMENT
20:40 A. Zilberstein, Tel Aviv University (109)
SUSTAINABILITY OF THE BT ENDOTOXIN CRY1C AS A NATURAL INSECTICIDE: FROM CRY1C-CROPS TO RECEPTOR HUNTING
21:00 I. Chet, Weizmann Institute (109)
BIOCONTROL AND INDUCED RESISTANCE: ENVIRONMENTALLY FRIENDLY APPROACH
21:20 C. Koncz, Max Planck Institute (110)
INTERACTIONS OF AMP-ACTIVATED PROTEIN KINASES WITH PROTEASOME AND SCF COMPLEXES
21:40 A.A. Szalay, University of Wurzburg (110)
VISUALIZATION OF TUMORS AND METASTASES IN LIVE ANIMALS WITH LIGHT
22:10 A. Barak, G.I.F German-Israeli Foundation for Scientific R&D and A. Ashri, Hebrew University
IN MEMORY OF PROF. JEFF SCHELL
21:30 - 22:30 Science and Society Session 2 Dan Hotel, Hall A
Round Table Discussion - Welfare or rights for animals in biomedical research
Chairperson: A. Tsafriri
R. Rahamimoff, Chief Scientist, Health Ministry
THE KNESSET AS A BATTLEGROUND ON ANIMAL EXPERIMENTATION IN BIOMEDICAL RESEARCH
E. Ziv, Hebrew University
ANIMAL EXPERIMENTATION: REGULATIONS, CONTROL AND RESPONSIBILITY
A. Tsafriri, Weizmann Institute
ANIMAL ACTIVISTS: PHILOSOPHY, TACTICS AND DANGER
Thursday, February 10, 2005
08:30 - 09:30 Plenary 5 Dan Hotel, Hall A
Chairperson: Y. Yarden
08:30 P.P. Di Fiore, The FIRC Institute of Molecular Oncology Foundation (4)
MONOUBIQUITINATION: ENDOCYTOSIS AND SIGNALLING
09:30 - 10: 00 Coffee Break
10:00 - 12:30 Parallel Session F-1: Signaling networks Dan Hotel, Hall A
Chairpersons: A. Aronheim, Y. Yarden
10:00 A. Levitzki, Hebrew University (111)
THE LOSS SIGNALING ROBUSTNESS UPON TRANSFORMATION
10:30 D. Engelberg, Hebrew University, Jexys Pharmaceuticals Ltd. (111)
DEVELOPENT OF CONSTITUTVELY ACTIVE VARIANTS OF MAP KINASES AND THEIR USES THEREOF
11:00 R. Seger, Weizmann Institute (112)
ERK1B, ERK1C AND ERK1D, A FAMILY OF ALTERNATIVE SPLICED FORMS OF ERK1
11:30 Y. Kloog, Tel Aviv University (112)
THE GALECTIN SWITCH OF RAS SIGNALS OUTPUT AND SELECTIVITY
12:00 U. Alon, Weizmann Institute (113)
STRUCTURE AND FUNCTION OF BIOLOGICAL NETWORKS
10:00 - 12:30 Parallel Session F-2: Immunity and allergy Dan Hotel, Hall B
Chairpersons: R.N. Apte, O. Mandelboim
10:00 D. Melamed, Technion (113)
CLASS SWITCH RECOMBINATION IN B-LYMPHOPOIESIS IS A NOVEL PATHWAY FOR DEVELOPMENT OF AUTOIMMUNE B CELLS
10:30 A. Porgador, Ben Gurion University (114)
RECOGNITION OF TUMORS BY NATURAL KILLER CELLS
11:00 S. Jung, Weizmann Institute (114)
ORIGINS AND FUNCTIONS IN THE MONONUCLEAR PHAGOCYTE SYSTEM
11:30 A. Peled, Hadassah Medical Center (115)
MOLECULAR AND CELLULAR MECHANISMS THAT REGULATE NK TRAFFICKING
12:00 D. Yablonski, Technion (115)
SIGNALING PATHWAYS MEDIATING CHEMOKINE-INDUCED
MIGRATION ACROSS RESTRICTIVE BARRIERS
12:15 S. Amzalleg, Ben Gurion University (116)
POST TRANSLATIONAL MODIFICATIONS BY O-GLYCOSYLATION OF TRANSCRIPTION FACTORS IN T-10 MURINE FIBROSARCOMA
Thursday, February 10, 2005 (continued)
10:00 - 12:30 Parallel Session F-3: Drug targeting and development Dan Hotel, Hall C
Chairpersons: Y. Kloog, M. Sokolovsky
10:00 A. Goldblum, Hebrew University (116)
NEW METHODOLOGIES FOR MODELING AND DESIGNING TARGETS, DRUGS AND THEIR INTERACTIONS
10:30 N. Livnah, Develogen Israel Ltd. (117)
DEVELOPMENT OF NOVEL ANTI-CANCER AGENTS BASED ON PROTEIN KINASE B (PKB) INHIBITORS
11:00 S.A. Ben-Sasson, Hebrew University (117)
TARGETING PROTEIN-KINASES: A GOLD-MINE OR A MINE-FIELD?
11:30 A. Freeman, Tel Aviv University (118)
TARGETING HUMAN PARASITIC FUNGI: DESIGN OF COMBINED DRUG/ENZYME ASSISTED THERAPIES
12:00 J.A. Hirsch, Tel Aviv University (118)
VOLTAGE-DEPENDENT CALCIUM CHANNEL MODULATION: TARGETING ALPHA1/BETA SUBUNIT INTERACTIONS
10:00 - 12:30 Parallel Session F-4: Bioinformatics Herods Forum Hotel, Hall E
Chairperson: R. Shamir
10:00 H. Margalit, Hebrew University (119)
CHROMOSOMAL ORGANIZATION IS SHAPED BY THE TRANSCRIPTION REGULATORY NETWORK
10:30 D. Lancet, Weizmann Institute (119)
THE GENECARDS SUITE: TRANSCRIPTOME ANNOTATION OF KNOWN AND UNKNOWN GENES
11:00 R. Sharan, Tel Aviv University (120)
CONSERVED PATTERNS OF PROTEIN INTERACTION IN MULTIPLE SPECIES
11:30 E. Eisenberg, Tel Aviv University (120)
METHODS FOR TRANSCRIPTOME-WIDE DETECTION OF A-TO-I EDITING SITES
12:00 R. Shamir, Tel Aviv University (121)
STABILITY AND CHANGE IN TRANSCRIPTION REGULATION: LESSONS FROM COMPARATIVE AND MICROARRAY ANALYSIS IN YEAST
10:00 - 12:30 Parallel Session F-5: Signaling networks in plant processes Herods Forum Hotel, Hall F
Chairperson: O. Yarden
10:00 G. Coupland, Max Planck Institute (121)
SIGNALLING PATHWAYS CONTROLLING FLOWERING TIME OF ARABIDOPSIS
10:30 Y. Eshed, Weizmann Institute (122)
SETTING BOUNDARIES BETWEEN CELL POPULATIONS BY MICRORNA MOLECULES
10:50 D. Weiss, Hebrew University (122)
CROSS TALK BETWEEN GIBBERELLIN AND CYTOKININ: THE ARABIDOPSIS GA-RESPONSE INHIBITOR SPINDLY PLAYS A POSITIVE ROLE IN CYTOKININ SIGNALING
11:10 S. Yalovsky, Tel Aviv University (123)
DECIPHERING RAC SIGNALING NETWORKS IN ARABIDOPSIS
Thursday, February 10, 2005 (continued)
11:30 G. Sessa, Tel Aviv University (123)
DISSECTING TOMATO RESISTANCE TO THE BACTERIAL PATHOGEN XANTHOMONAS CAMPESTRIS PV. VESICATORIA
11:50 U. Sonnewald, Institute of Plant Genetics and Crop Plant Research (124)
REPROGRAMMING LEAF METABOLISM BY PATHOGENS
12:20 E. Tel-Or, Hebrew University
CONCLUSION
MONDAY, JANUARY 28, 2008
16:00 - 16:30 Opening Ceremony Hall A, Herods Forum
Opening Remarks: Eliora Z. Ron, FISEB President
Rami Rahamimoff, Chief Scientist, Ministry of Health
Dan Zilberstein, Congress Chair
Arie Moran, Congress Co-Chair
16:30 - 17:30 Plenary 1 Hall A, Herods Forum
Chairperson: E.Z. Ron
16:30 A. Goldberg, Harvard University, USA
FUNCTIONS OF THE PROTEASOME: FROM PROTEIN DEGRADATION AND ANTIGEN PRESENTATION TO CANCER THERAPY
17:30 - 18:00 Coffee Break & Exhibition
18:00 - 20:30 Parallel Session A-1: Cancer biology and therapeutics:
molecular mechanisms and emerging therapeutic strategies Hall B, Herods Forum
Chairpersons: Y.G. Assaraf, Y. Shiloh
18:00 Y.G. Assaraf, Technion-Israel Institute of Technology
A NOVEL ABCG2-DEPENDENT MECHANISM OF MULTIDRUG RESISTANCE
18:25 Y. Shiloh, Tel Aviv University
THE ATM-MEDIATED DNA DAMAGE RESPONSE: BRANCHING OUT
18:50 Y. Ben-Neriah, Hebrew University - Hadassah Medical School
MOLECULAR MECHANISMS FOR LIVER TUMOR INHIBITION BY NON-STEROIDAL
ANTI-INFLAMMATORY DRUGS
19:15 E. Keshet, Hebrew University
VEGF AND ANGIOGENIC ACCESSORY CELLS
19:40 G. Rechavi, Sheba Cancer Research Center and Tel Aviv University
REGULATION OF EXPRESSION OF CODING AND NON-CODING RNA BY A-TO-I EDITING
20:05 Y. Salomon, Weizmann Institute of Science
VASCULAR-TARGETED PHOTODYNAMIC THERAPY (VTP), A NEW ANTI-VASCULAR STRATEGY FOR TREATMENT OF SOLID TUMORS: FROM THE LAB TO THE CLINIC
18:00 - 20:30 Parallel Session A-2: Global warming Hall C, Herods Forum
Chairpersons: M. Horowitz, D. Tchernov
18:00 T. Dayan, Tel Aviv University
PLANNING FOR THE FUTURE: GLOBAL CLIMATE CHANGE AND BIODIVERSITY
18:25 A. Kaplan, Hebrew University
CAN WE IDENTIFY THE LANGUAGES SPOKEN WITHIN AND BETWEEN PHYTOPLANKTON POPULATIONS IN A CHANGING WORLD?
18:50 D. Tchernov, Hebrew University and Interuniversity of Marine Science
THE EFFECT OF GLOBAL CLIMATE CHANGE ON CORALS REEFS: BLEACHING AND SKELETON LOSS
19:15 M. Horowitz, Hebrew University
THERMAL ADAPTIVE PLASTICITY AND LIMITS OF TOLERATION - MOLECULAR PHYSIOLOGICAL LINKAGE
19:40 D.S. Moran, Chaim Sheba Medical Center and Tel Aviv University
HEAT INTOLERANCE IN YOUNG POPULATIONS AT RISK
20:05 A. Huppert, Chaim Sheba Medical Center
CAN WE PREDICT FUTURE TRENDS OF INFECTIOUS DISEASES DYNAMICS CONNECTED WITH FUTURE CLIMATE CHANGE?
MONDAY, JANUARY 28, 2008 (continued)
18:00 - 20:30 Parallel Session A-3: microRNA - from plants to humans in
development, health and disease Hall D, Dan
Chairpersons: E. Galun, E. Hornstein
18:00 E. Hornstein, Weizmann Institute of Science
miRNA ROLE IN DEVELOPMENT ORGAN FUNCTION
18:25 H. Margalit, Hebrew University
HOST-PATHOGEN CROSS-TALK VIA miRNA
18:50 O. Mandelboim, Hebrew University - Hadassah Medical School
VIRAL AND HUMAN microRNAs USE SHARED TARGET SEQUENCES TO REGULATE THE IMMUNE RESPONSE TO STRESS
19:15 Y. Eshed, Weizmann Institute of Science
THE TOMATO GENE SILENCING PATHWAY
19:40 K.B. Avraham, Tel Aviv University
THE SEARCH FOR BIOLOGICAL NETWORKS OF HEARING: COMBINING GENOMIC, PROTEOMIC AND microRNA CHARACTERIZATION
20:05 S. Yekta, MIT, USA
microRNA REGULATION OF VERTEBRATE-Hox GENES
18:00 - 20:30 Parallel Session A-4: Protein targeting and localized protein synthesis Hall E, Dan
Chairpersons: E. Bibi, J.K. Yisraeli
18:00 J.E. Gerst, Weizmann Institute of Science
TARGETED mRNA-ER CO-TRAFFICKING AND ITS ROLE IN PROTEIN LOCALIZATION AND CELL GROWTH
18:25 J.K. Yisraeli, Hebrew University
BEING IN THE RIGHT PLACE AT THE RIGHT TIME: THE ROLE OF THE RNA BINDING VICKZ PROTEINS IN LAMELLIPODIA FORMATION AND CELL MIGRATION
18:50 E. Bibi, Weizmann Institute of Science
THE SRP-RECEPTOR OF E. COLI: A TALE OF ONE AMINO ACID
19:15 O. Amster-Choder, Hebrew University - Haddasah Medical School
REGULATION OF TRANSCRIPTION IN RESPONSE TO ENVIRONMENTAL CUES BY
SUB-CELLULAR LOCALIZATION OF SIGNALING PROTEINS
19:40 A. Azem, Tel Aviv University
THE MITOCHONDRIAL PROTEIN TRANSLOCATION MOTOR: A STUDY WITH PURIFIED COMPONENTS
20:05 I. Rosenshine, Hebrew University
REAL TIME ANALYSIS OF EFFECTOR TRANSLOCATION BY THE TYPE III SECRETION SYSTEM OF ENTEROPATHOGENIC E. COLI
MONDAY, JANUARY 28, 2008 (continued)
18:00 - 20:30 Parallel Session A-5: Metagenomic and functional genomic
of microorganisms Hall G, Royal Beach
Chairpersons: O. Beja, U. Gophna
18:00 R. Sorek, Berkeley National Laboratory, USA
DISCOVERY OF BIO-FUEL SOLUTIONS AND NEW ANTIBIOTICS THROUGH ANALYSIS OF 100 GENOMES
18:25 A. Shafferman, Israel Institute for Biological Research
FUNCTIONAL GENOMICS IN BACILLUS ANTHRACIS
18:50 O. Beja, Technion-Israel Institute of Technology
METAGENOMICS OF VIRAL 'PHOTOSYNTHESIS'
19:15 S. Pietrokovski, Weizmann Institute of Science
BOUNTY OF THE SEA - INTEIN AND INTEIN-LIKE DOMAINS IN ENVIRONMENTAL SEQUENCE DATA
19:40 E. Jurkevitch, Hebrew University
DECIPHERING THE LIFE-CYCLE OF THE PREDATORY BACTERIUM BDELLOVIBRIO BACTERIOVORUS WITH PROTEOMICS
20:05 U. Gophna, Tel Aviv University
IS PROTEIN COMPLEXITY A BARRIER TO LATERAL GENE TRANSFER?
18:00 - 20:30 Parallel Session A-6: Synaptic function and plasticity Hall H, Royal Beach
Chairpersons: R. Rahamimoff, U. Ashery
18:00 U. Ashery, Tel Aviv University
TOMOSYN INHIBITS EXOCYTOSIS BY INTERFERING WITH GRANULE IMMOBILIZATION
18:25 R. Rahamimoff, Hebrew University - Hadassah Medical School
SECRETORY VESICLES MAY CONTROL CYTOSOLIC CALCIUM CONCENTRATION
18:50 A. Mizrahi, Hebrew University
LIVE IMAGING OF SYNAPTOGENESIS IN THE MOUSE OLFACTORY BULB
19:15 M.E. Spira, Hebrew University
PHYSIOLOGICAL AND PATHOLOGICAL FUNCTIONS OF CALPAIN IN NEURONS AND SYNAPSES
19:40 I. Slutsky, Tel Aviv University
AMYLOID-BETA PEPTIDE: FROM SYNAPTIC RELEASE TO INFORMATION PROCESSING IN NEURONAL NETWORKS
20:05 D. Gitler, Ben-Gurion University of the Negev
SYNAPSINS AS DETERMINANTS OF SYNAPTIC FUNCTION AND DYSFUNCTION IN THE CNS
20:30 Welcome Cocktail Pool Area, Dan
TUESDAY, JANUARY 29, 2008
07:00 - 08:00 Early Bird 1: Proteomics and genomics Hall F, Dan
Chairperson: R. Rosen
07:00 R. Rosen, Agentek (1987) Ltd.
FRONTIERS IN MASS SPECTROMETRY FOR ANALYSIS OF BIOLOGICAL MOLECULES - PROTEOMICS, METABOLOMICS AND IMAGING
07:30 R. Forer, DYN Diagnostics Ltd.
ROCHE/454 GENOME SEQUENCER FLX SYSTEM - REVOLUTIONARY TECHNOLOGY FOR HIGH THROUGH PUT DNA SEQUENCING
09:00 - 10:00 Plenary 2: Nobel 2006 Hall A, Herods Forum
Chairperson: H. Soreq
09:00 R. Kornberg, Stanford University, USA
THE MOLECULAR BASIS OF EUKARYOTIC TRANSCRIPTION
10:00 – 10:30 Coffee Break & Exhibition
10:30 - 13:00 Parallel Session B-1: The molecular basis of diseases Hall A, Herods Forum
Chairpersons: B. Kerem, O.S. Birk
10:30 O. Elpeleg, Hadassah - Hebrew University Medical Center
DEFECTS IN MITOCHONDRIAL PROTEIN SYNTHESIS
10:55 E. Sprecher, Technion-Israel Institute of Technology
KERATINOPATHIES: FROM HEAD TO TAIL
11:20 L. Basel-Vanagaite, Schneider Children's Medical Center and Tel Aviv University
IDENTIFICATION OF TWO NOVEL GENES CAUSING COGNITIVE IMPAIRMENT AND AN OVERVIEW OF MOLECULAR MECHANISMS CONTRIBUTING TO MENTAL RETARDATION
11:45 J. Melki, Hadassah University Hospital
HUMAN MOTOR NEURON DISEASES: INSIGHTS FROM GENETICS AND ANIMAL MODELS
12:10 O.S. Birk, Ben-Gurion University of the Negev and Soroka Medical Center
FROM DISEASE GENES TO DISEASE MECHANISMS
12:35 M. Weil, Tel Aviv University
CHICKS AND HUMAN EMBRYONIC STEM CELLS: DEVELOPMENTAL PLATFORMS TO STUDY FAMILIAL DYSAUTONOMIA
10:30 - 13:00 Parallel Session B-2:
Molecular mechanism of transcription regulation Hall B, Herods Forum
Chairpersons: Y. Groner, R. Ashery-Padan
10:30 Y. Groner, Weizmann Institute of Science
LONG RANGE ENHANCER - PROMOTER COMMUNICATIONS
10:55 R. Shamir, Tel Aviv University
TRANSCRIPTIONAL REGULATORY ELEMENTS: THEIR EVOLUTION, SELECTION AND DETECTION
11:20 M. Choder, Technion-Israel Institute of Technology
TRANSCRIPTION AND mRNA DECAY ARE COORDINATELY REGULATED BY COMMON SHUTTLING FACTORS
11:45 R. Dikstein, Weizmann Institute of Science
UNEXPECTED LINKS BETWEEN THE MAMMALIAN CORE PROMOTER TO TRANSCRIPTION ELONGATION AND PROTEIN TRANSLATION
12:10 R. Ashery-Padan, Tel Aviv University
DUAL ROLE OF Pax6 WITHIN TWO DISTINCT RETINAL PROGENITOR CELL POOLS
12:35 H. Fromm, Tel Aviv University
CALCIUM-REGULATED TRANSCRIPTION: LESSONS FROM PLANTS TO HUMAN
TUESDAY, JANUARY 29, 2008 (continued)
10:30 - 13:00 Parallel Session B-3: Symbiosis and evolution Hall C, Herods Forum
Chairpersons: E. Rosenberg, A. Kushmaro
10:30 A. Korol, University of Haifa
ONGOING SYMPATHRIC DIFFERENTIATION IN NATURE: A CASE STUDY WITH DROSOPHILA AT MOUNT CARMEL
10:55 L.I. Brodsky, University of Haifa
DIVERGENT PATTERNS OF RICOTIA LUNARIA GENOME TRANSCRIPTION ON OPPOSITE SLOPES OF 'EVOLUTION CANYON' REVEALED BY FULL GENOME (TILING) ARRAY HYBRIDIZATIONS
11:20 O. Levy, University of Queensland, Australia
LIGHT-RESPONSIVE CRYPTOCHROMES FROM A SIMPLE MULTICELLULAR ANIMAL, THE CORAL ACROPORA MILLEPORA
11:45 A. Kushmaro, Ben-Gurion University of the Negev
BENEFICIAL SYMBIOTIC MICROORGANISMS IN CORALS
12:10 E. Jablonka, Tel Aviv University
EVOLUTIONARY THEORY IN THE 21st CENTURY: BEYOND THE MODERN SYNTHESIS?
12:35 E. Rosenberg, Tel Aviv University
FROM BACTERIAL BLEACHING TO THE HOLOGENOME THEORY OF EVOLUTION
10:30 - 13:00 Parallel Session B-4: Harvesting the sun - photosynthesis and beyond Hall D, Dan
Chairpersons: N. Nelson, A. Scherz
10:30 N. Nelson, Tel Aviv University
A GLIMPSE INTO THE ATOMIC STRUCTURE OF PLANT PHOTOSYSTEM I - BILLION YEARS OF PERFECTION
10:55 C. Carmeli, Tel Aviv University
HIGHLY EFFICIENT HYBRID BIO-METAL AND SEMICONDUCTOR NANO PHOTOVOLTAIC AND PHOTO SENSOR DEVICES
11:20 A. Scherz, Weizmann Institute of Science
NOVEL PARADIGMS UNDERLAY OPTIMIZATION AND TEMPERATURE ADAPTATION OF PHOTOSYNTHETIC ELECTRON TRANSFER
11:45 U. Pick, Weizmann Institute of Science
MICROALGAE AS MODEL PHOTOSYNTHETIC EXTREMOPHILES AND A SOURCE FOR GREEN ENERGY AND SPECIAL BIIOCHEMICALS
12:10 N. Keren, Hebrew University
METAL TRANSPORT IN PHOTOSYNTHETIC ORGANISMS: LESSONS FROM THE CYANOBACTERIAL IRON TRANSPORT PATHWAY
12:35 N. Adir, Technion-Israel Institute of Technology
CRYSTAL STRUCTURES OF THE CYANOBACTERIAL PHYCOBILISOME ANTENNA COMPLEX: ASSEMBLY AND DISASSEMBLY OF A GIANT
TUESDAY, JANUARY 29, 2008 (continued)
10:30 - 13:00 Parallel Session B-5:
Calcium channels and calcium modulated channels Hall E, Dan
Chairpersons: N. Dascal, A. Moran
10:30 J.A. Hirsch, Tel Aviv University
STRUCTURAL AND FUNCTIONAL ASPECTS OF VOLTAGE-DEPENDENT CALCIUM CHANNEL SIGNALING
10:55 D. Atlas, Hebrew University
THE VOLTAGE-GATED Ca2+ CHANNEL IS THE Ca2+ SENSOR PROTEIN OF STIMULUS- SECRETION COUPLING
11:20 V. Shoshan-Barmatz, Ben-Gurion University of the Negev
IDENTIFICATION AND CHARACTERIZATION OF CA2+-BINDING PROTEINS AND LOCALIZATION OF THEIR CA2+-BINDING SITES USING AZIDO RUTHENIUM: A NOVEL PHOTOREACTIVE REAGENT
11:45 B. Minke, Hebrew University
TRP CHANNELS, WHAT ARE THEY AND WHY ARE THEY IMPORTANT
12:10 N. Dascal, Tel Aviv University
REGULATION OF CALCIUM CHANNEL GATING BY THE CYTOSOLIC DOMAIN AND AUXILIARY SUBUNITS AND PROTEINS
12:35 A. Moran, Ben-Gurion University of the Negev
REGULATION OF THE L-TYPE Ca2+ CHANNEL BY THE UBIQUITOUS PROTEIN ZnT-1
10:30 - 13:00 Parallel Session B-6: Stem cells and organ formation Hall F, Dan
Chairpersons: J. Itskovitz-Eldor, J. Leor
10:30 Y. Bergman, Hebrew University Medical School
A MULTISTEP EPIGENETIC MECHANISM FOR THE INACTIVATION OF EMBRYONIC- SPECIFIC GENES
10:55 Y. Soen, Weizmann Institute of Science
COORDINATION BETWEEN GENE AND microRNA PROGRAMS OF HUMAN EMBRYONIC STEM CELL DIFFERENTIATION
11:20 M. Amit, Technion-Israel Institute of Technology
SUSPENSION CULTURE OF UNDIFFERENTIATED HUMAN EMBRYONIC STEM CELLS
11:45 A. Nagler, Chaim Sheba Medical Center
NOVEL APPROACHES FOR HARVESTING, CRYOPRESERVATION, EXPANSION AND TISSUE REGENERATION POTENTIAL OF HUMAN UMBILICAL CORD BLOOD
12:10 S. Efrat, Tel Aviv University
EX VIVO EXPANSION OF ADULT HUMAN PANCREATIC ISLETS FOR CELL THERAPY OF DIABETES
12:35 R. Gorodetsky, Hadassah University Medical Center
TISSUE REGENERATION BASED ON FIBRIN MICROBEADS (FMB) FOR SOMATIC STEM CELLS ISOLATION, EXPANSION DIFFERENTIATION AND IMPLANTATION
TUESDAY, JANUARY 29, 2008 (continued)
10:30 - 13:00 Parallel Session B-7: Bioinformatics: from genome
to proteome Hall G, Royal Beach
Chairpersons: Y. Mandel-Gutfreund, H. Margalit
10:30 I. Simon, Hebrew University – Hadassah Medical School
A HIGH RESOLUTION MAP OF MOUSE GENOME REPLICATION TIMING SUGGESTS A ROLE IN GENE REGULATION
10:55 Y. Mandel-Gutfreund, Technion-Israel Institute of Technology
ALTERNATIVE SPLICING REGULATION: LESSONS FROM THE GENOME
11:20 T. Pilpel, Weizmann Institute of Science
COPING WITH GENETIC AND NON-GENETIC STRESS
11:45 Y. Ofran, Bar-Ilan University
MOLECULAR MECHANISMS THAT CONTROL BIOLOGICAL NETWORKS
12:10 R. Sharan, Tel Aviv University
A SYSTEMS-LEVEL APPROACH TO MAPPING THE TELOMERE-LENGTH MAINTENANCE GENE CIRCUITRY
12:35 M. Linial, Hebrew University
DESIGN PRINCIPLES OF A FUNCTIONAL SYNAPSE: INSIGHTS FROM HUMAN AND INSECTS PROTEOMES
10:30 - 13:00 Parallel Session B-8: Innate immunity and inflammation Hall H, Royal Beach
Chairpersons: O. Mandelboim, A. Porgador
10:30 Y. Shai, Weizmann Institute of Science
INNATE IMMUNITY HOST DEFENCE ANTIMICROBIAL PEPTIDES: ROLE IN MICROBIAL CLEARANCE, ENDOTOXIN NEUTRALIZATION AND CANCER THERAPY
10:55 R.N. Apte, Ben-Gurion University of the Negev
THE DIVERSE AND DISTINCT EFFECTS OF MOLECULES OF THE IL-1 FAMILY IN TUMOR- HOST INTERACTIONS
11:20 S. Jung, Weizmann Institute of Science
THE BONE MARROW IMMUNE NICHE - PERIVASCULAR DENDRITIC CELLS PROVIDE CRITICAL B CELL SURVIVAL SIGNALS
11:45 F. Levi-Schaffer, Hebrew University
THE ALLERGIC SYNAPSE IN THE ALLERGIC NICHE: A NOVEL VIEW OF THE ALLERGIC INFLAMMATION
12:10 D. Mevorach, Hebrew University - Hadassah University Hospital
CLEARANCE OF APOPTOTIC CELLS BY DENDRITIC CELLS
12:35 A. Ariel, University of Haifa
PRO-RESOLVING MACROPHAGES AND THEIR REGULATION BY RESOLVINS
13:00 – 14:30 Lunch & Exhibition
TUESDAY, JANUARY 29, 2008 (continued)
14:30 - 17:00 Parallel Session C-1: Pattern formation and morphogenesis Hall A, Herods Forum
Chairpersons: A. Salzberg, B.-Z. Shilo
14:30 A. Salzberg, Technion-Israel Institute of Technology
THE bHLH PROTEIN DELILAH AFFECTS INTERVEIN CELL DIFFERENTIATION BY REGULATING THE EXPRESSION OF CELL ADHESION MOLECULES
14:55 Z. Paroush, Hebrew University
REGULATION OF GROUCHO/TLE-DEPENDENT TRANSCRIPTIONAL REPRESSION BY RECEPTOR TYROSINE KINASE SIGNALING
15:20 N. Ori, Hebrew University
LEAF PATTERNING IN TOMATO
15:45 Y. Dor, Hebrew University - Hadassah Medical School
A MOLECULAR NETWORK CONTROLLING PANCREATIC BETA CELL SIZE, POLARITY AND FUNCTION
16:10 B. Podbilewicz, Technion-Israel Institute of Technology
THE FIRST FAMILY OF DEVELOPMENTAL CELL-CELL FUSION PROTEINS
16:35 N. Barkai, Weizmann Institute of Science
SIZE-DEPENDENT SCALING OF BMP ACTIVATION GRADIENT: IMPLICATIONS FOR SIZE- REGULATION AND AXIS-DUPLICATION
14:30 - 17:00 Parallel Session C-2: Translation regulation in eukaryotes Hall B, Herods Forum
Chairpersons: M. Shapira, Y. Arava
14:30 M. Shapira, Ben-Gurion University of the Negev
RNA THERMOSENSORS AND TRANSLATION REGULATION IN LEISHMANIA
14:55 A. Aharoni, Weizmann Institute of Science
RIBOSWITCH-DEPENDENT GENE REGULATION AND ITS EVOLUTION IN THE PLANT KINGDOM
15:20 O. Elroy-Stein, Tel Aviv University
A POINT MUTATION IN TRANSLATION INITIATION FACTOR 2B5 LEADS TO BRAIN PATHOLOGY
15:45 L. Vardimon, Tel Aviv University
NOVEL MECHANISM OF c-JUN REGULATION IN NORMAL AND MALIGNANT CELLS
16:10 Y. Arava, Technion-Israel Institute of Technology
YEAST TRANSLATIONAL RESPONSE TO HIGH SALINITY: GLOBAL ANALYSIS REVEALS REGULATION AT MULTIPLE LEVELS
16:35 O. Meyuhas, Hebrew University - Hadassah Medical School
A COMMON PATHWAY TRANSDUCES VARIOUS STRESS SIGNALS INTO
TRANSLATIONAL REPRESSION OF TOP mRNAs
TUESDAY, JANUARY 29, 2008 (continued)
14:30 - 17:00 Parallel Session C-3:
Bioremediation and conservation of the environment Hall C, Herods Forum
Chairpersons: C. Dosoretz, I. Chet
14:30 A. Fishman, Technion-Israel Institute of Technology
USE OF NATURAL ISOLATES OF SACCHAROMYCES CEREVISIAE STRAINS FOR GREEN CHEMISTRY
14:55 M. Herzberg, Ben-Gurion University of the Negev
GENETIC TRAITS AND PHYSIOLOGY OF REVERSE OSMOSIS MEMBRANE BIOFILMS: DEVELOPMENT OF BIOFOULING CONTROL STRATEGIES
15:20 Y. Hadar, Hebrew University
BIODEGRADATION OF ENVIRONMENTAL HAZARDS: THE ROLE OF WHITE ROT FUNGI
15:45 D. Minz, Agriculture Research Organization, Volcani Center
WASTEWATER IRRIGATION: EFFECTS ON SOIL MICROBIAL ACTIVITIES AND COMMUNITY COMPOSITION
16:10 S. Belkin, Hebrew University
WHOLE-CELL BIOSENSORS FOR ENVIRONMENTAL MONITORING:
ADVANCED APPLICATIONS
16:35 E.Z. Ron, Tel Aviv University
THE ENERGY CRISIS - HOW CAN MICROORGANISMS BE PUT TO WORK?
14:30 - 17:00 Parallel Session C-4: Protein degradation and quality control Hall D, Dan
Chairpersons: A. Azem, D. Kornitzer
14:30 M.H. Glickman, Technion-Israel Institute of Technology
A MASON'S APPROACH TO THE 19S REGULATORY COMPLEX OF THE PROTEASOME
14:55 M. Sharon, Weizmann Institute of Science
NEW INSIGHTS INTO THE PROTEIN DEGRADATION MACHINERY FROM MASS SPECTROMETRY
15:20 A. Stanhill, Technion-Israel Institute of Technology
PROTEASOMAL ADAPTATION TO ENVIRONMENTAL STRESS LINKS RESISTANCE TO PROTEOTOXICITY WITH LONGEVITY
15:45 Z. Adam, Hebrew University
THYLAKOID PROTEASES IN HIGHER PLANTS - ROLES IN PROTEIN QUALITY CONTROL
16:10 P. Goloubinoff, Lausanne University, Switzerland
MECHANISM OF Hsp70-MEDIATED REMODELING OF ALTERNATIVELY FOLDED PROTEINS INTO NATIVELY FOLDED PROTEINS
16:35 G. Prag, Tel Aviv University
STRUCTURAL MECHANISMS FOR TRAFFICKING OF UBIQUITYLATED
MEMBRANE-PROTEINS
TUESDAY, JANUARY 29, 2008 (continued)
14:30 - 17:00 Parallel Session C-5: Signal transduction Hall E, Dan
Chairpersons: E. Banin, R. Seger
14:30 E. Banin, Bar-Ilan University
IRON AND CELL-CELL SIGNALING IN PSEUDOMONAS AERUGINOSA BIOFILM DEVELOPMENT
14:55 D. Engelberg, Hebrew University
CONSTITUTIVELY ACTIVE VARIANTS OF p38s AND ERKs MAP KINASES - MECHANISM OF ACTION AND BIOLOGICAL ACTIVITIES
15:20 G. Sessa, Tel Aviv University
PATHOGEN RECOGNITION AND SIGNAL TRANSDUCTION IN TOMATO INNATE IMMUNITY
15:45 Y. Kloog, Tel Aviv University
NEW INTRACELLULAR AND INTERCELLULAR PARADIGMS IN Ras SIGNALING: NANOAWICHES, RASOSOMES AND Ras TRANSFER FROM CELL TO CELL
16:10 D. Wallach, Weizmann Institute of Science
MOLECULAR AND PHYSIOLOGICAL DISSECTION OF FUNCTIONAL ROLES OF DEATH MOLECULES ACTIVATED BY RECEPTORS OF THE TNF/NGF FAMILY
16:35 R. Seger, Weizmann Institute of Science
THE ERK/MAPK SIGNALING CASCADE: NUCLEAR SHUTTLING ON THE WAY TO PROLIFERATION
14:30 - 17:00 Parallel Session C-6: Biological mechanisms of neurodegeneration Hall F, Dan
Chairpersons: R. Gabizon, D.M. Michaelson
14:30 T. Brenner, Hadassah Hebrew University
INFLAMMATORY CIRCUITS IN THE CHOLINERGIC SYSTEM
14:55 R. Sharon, Hebrew University – Hadassah School of Medicine
ALPHA SYNUCLEIN INTERACTIONS WITH POLYUNSATURATED FATTY ACIDS: IMPLICATIONS IN HEALTH AND PARKINSON'S DISEASE
15:20 D.M. Michaelson, Tel Aviv University
CROSS TALK AND SYNERGISTIC INTERACTIONS BETWEEN MOLECULAR AND GENETIC RISK FACTORS OF ALZHEIMER'S DISEASE
15:45 A. Monsonego, Ben-Gurion University of the Negev
IMMUNE REGULATION AND NEURONAL REPAIR IIN THE PROGRESSION OF ALZHEIMER'S DISEASE
16:10 D. Offen, Tel Aviv University
ADULT STEM CELL THERAPY IN NEURODEGENERATIVE DISEASES
16:35 R. Gabizon, Hadassah University Hospital
CO-INFECTION OF SCRAPIE AND EAE: PATHOLOGY AND SECOND GENERATION TRANSMISSION
TUESDAY, JANUARY 29, 2008 (continued)
14:30 - 17:00 Parallel Session C-7: Stress responses Hall G, Royal Beach
Chairpersons: N. Moran, S. Barak
14:30 I. Berman-Frank, Bar-Ilan University
ENVIRONMENTAL STRESSORS INDUCE AN AUTOCATALYTIC PROGRAMMED CELL DEATH IN THE GLOBALLY IMPORTANT CYANOBACTERIUM TRICHODESMIUM
14:55 D. Zilberstein, Technion-Israel Institute of Technology
STRESS SIGNALS THE INTRACELLULAR DIFFERENTIATION OF THE PARASITIC PROTOZOA LEISHMANIA
15:20 M. Moshelion, Hebrew University
VACUOLES ROLE IN REGULATING PLANT STRESS RESPONSE
15:45 R. Hedrich, University of Wuerzburg, Germany
STRESS SIGNALLING IN GUARD CELLS - NEW INSIGHTS FROM ELECTROPHYSIOLOGICAL STUDIES IN INTACT PLANTS
16:10 H. Soreq, Hebrew University
CHOLINESTERASE MODULATIONS OF MAMMALIAN STRESS AND ANXIETY REACTIONS
16:35 E. Nevo, University of Haifa
STRESS AND EVOLUTION: LESSONS FROM NATURE
14:30 - 17:00 Parallel Session C-8: Ion transport and homeostasis:
from protein structure to environment Hall H, Royal Beach
Chairpersons: E. Padan, R. Rao
14:30 E. Padan, Hebrew University
STRUCTURE BASED STUDY OF NhaA, Na+/H+ ANTIPORTER
14:55 I.T. Arkin, Hebrew University
MECHANISM OF Na+/H+ ANTIPORTING
15:20 R. Rao, Johns Hopkins University School of Medicine, USA
NOVEL MEMBERS OF THE CATION/PROTON ANTIPORTER SUPERFAMILY
16:10 N. Ben-Tal, Tel Aviv University
MODEL STRUCTURE OF THE NA+/H+ EXCHANGER 1 (NHE1): FUNCTIONAL AND CLINICAL IMPLICATIONS
16:35 A. Oren, Hebrew University
ION HOMEOSTASIS IN HALOPHILIC ARCHAEA AND BACTERIA: PHYSIOLOGICAL AND ENVIRONMENTAL ASPECTS
17:00 – 17:30 Coffee Break & Exhibition
17:30 - 18:30 Plenary 3 Hall A, Herods Forum
Chairperson: Y. Reiter
17:30 E. Hurvitz, Teva Pharmaceutical Industries Ltd.
עתיד תעשיית ה-healthcare בישראל - היבטים כלכליים
20:00-22:30 Poster Session A Zones 1, 2 & 3
WEDNESDAY, JANUARY 30, 2008
07:00 - 08:00 Early Bird 2: Heterologous gene expression Hall E, Dan
Chairperson: T. Danieli
07:00 T. Danieli, Hebrew University
OVER-EXPRESSION FOR UNDER ACHIEVERS: SPECIAL MEASURES FOR YOUR EXPRESSION-CHALLENGED PROTEIN
07:30 N. Kleinberger-Doron, Hebrew University
INTEGRATING BIOINFORMATICS ANALYSES AND EXPERIMENTAL DATA FOR STRATEGIC DESIGN AND TROUBLESHOOTING DURING PROTEIN EXPRESSION
07:00 - 08:00 Early Bird 3: Insights into microRNA and real time PCR technologies Hall F, Dan
Chairperson: A. Admon
07:00 G. Mertes, QIAGEN GmbH, Germany
EFFICIENT AND SPECIFIC QUANTIFICATION OF MAMMALIAN microRNAs USING A NOVEL REAL-TIME PCR APPROACH
09:00 - 10:00 Plenary 4 Hall A, Herods Forum
Chairperson: D. Zilberstein
09:00 K. Stuart, Seattle Biomedical Institute and University of Washington, USA
RNA EDITING: A COLLABORATION OF MULTIPLE PROTEIN COMPLEXES
10:00 – 10:30 Coffee Break & Exhibition
10:30 - 13:00 Parallel Session D-1: Programmed cell death across evolution:
from single genes towards systems level studies Hall A, Herods Forum
Chairpersons: A. Kimchi, R. Stein
10:30 H. Engelberg-Kulka, Hebrew University - Hadassah Medical School
A NOVEL COMMUNICATION PEPTIDE IS REQUIRED FOR PROGRAMMED CELL DEATH IN BACTERIA
10:55 E. Arama, Weizmann Institute of Science
REGULATION OF CASPASE ACTIVATION DURING DROSOPHILA SPERMATOGENESIS
11:20 S. Larisch, Rambam Medical Center
THE MITOCHONDRIAL IAP-ANTAGONIST ARTS, PROMOTES APOPTOSIS THROUGH A DISTINCT MECHANISM OF ACTION
11:45 A. Gross, Weizmann Institute of Science
BID: A PIVOTAL REGULATOR OF CELL LIFE AND DEATH DECISIONS
12:10 A. Kimchi, Weizmann Institute of Science
SYSTEMS LEVEL ANALYSIS OF PROGRAMMED CELL DEATH: SWITCHING BETWEEN APOPTOSIS, AUTOPHAGY AND PROGRAMMED NECROSIS
12:35 U. Alon, Weizmann Institute of Science
DYNAMICS OF THE PROTEOME AS INDIVIDUAL HUMAN CELLS RESPOND TO AN
ANTI-CANCER DRUG
WEDNESDAY, JANUARY 30, 2008 (continued)
10:30 - 13:00 Parallel Session D-2: Emerging diseases Hall B, Herods Forum
Chairpersons: B. Rager, A. Shafferman
10:30 Y. Carmeli, Tel Aviv Sourasky Medical Center
THE SPREAD OF BETA-LACTAMASES IN ISRAEL
10:55 D.G. Wolf, Hadassah University Medical Center
EPIDEMIOLOGY AND EVOLVING CLINICAL ASPECTS OF THE NEWLY DISCOVERED HUMAN METAPNEUMOVIRUS
11:20 M.G. Friedman, Ben-Gurion University of the Negev
SIMKANIA NEGEVENSIS, AN EMERGING MICROBE THAT WAS NEVER FAR AWAY
11:45 A. Keysary, Israel Institute for Biological Research
TICK-BORNE RICKETTSIAL AND EHRLICHIAL DISEASES IN ISRAEL - WHAT'S NEW?
12:10 Y. Pollack, Ben-Gurion University of the Negev
CAN VAR GENE MODULATION SERVE AS A NOVEL TARGET FOR MALARIA THERAPY?
12:35 E. Mendelson, Ministry of Health, Chaim Sheba Medical Center and Bar-Ilan University
EMERGING AND RE-EMERGING VIRAL DISEASES IN ISRAEL
10:30 - 13:00 Parallel Session D-3: Adaptation to extreme environments Hall C, Herods Forum
Chairpersons: A. Haim, J. Eichler
10:30 A. Minsky, Weizmann Institute of Science
RECOMBINATION DNA REPAIR IN THE CELLULAR CONTEXT
10:55 S. Yurist-Doutsch, Ben-Gurion University of the Negev
SWEET AND SALTY: PROTEIN GLYCOSYLATION IN ARCHAEA
11:20 M. Fine, Bar-Ilan University and Interuniversity Institute for Marine Sciences
CORALS AND CORAL REEFS IN A CHANGING WORLD
11:45 D. Bar-Zvi, Ben-Gurion University of the Negev
ROLE OF HYDROPHILINS IN ADAPTATION OF PLANTS TO DROUGHT AND SALINITY
12:10 E. Lachman, Hebrew University
THE EFFECT OF HEAT STRESS AND DESICCATION ON THE LAND SNAIL LEVANTINA HIEROSOLYMA
12:35 H. Schwimmer, University of Haifa
THE COMBINED STRESS OF HEAT AND HYPOHYDRATION: INTEGRATIVE, GENOMIC, AND PROTEOMIC APPROACHES
WEDNESDAY, JANUARY 30, 2008 (continued)
10:30 - 13:00 Parallel Session D-4: RNA world and processing Hall D, Dan
Chairpersons: S. Michaeli, G. Kaufman
10:30 S. Michaeli, Bar-Ilan University
TRANS-SPLICING - A MASTER REGULATOR AND A HIGHLY CONTROLLED PROCESS IN TRYPANOSOMES
10:55 S. Altuvia, Hebrew University
ALTERNATIVE RNA STRUCTURES CONTROL THE TRANSLATION OF THE DOWNSTREAM GENE ALX IN RESPONSE TO ALKALINE CONDITIONS
11:20 R. Sperling, Hebrew University
REGULATION OF ALTERNATIVE SPLICING IN CELL NUCLEI
11:45 G. Ast, Tel Aviv University
Alu EXONIZATION - TWO ARMS ARE BETTER THAN ONE
12:10 G. Schuster, Technion-Israel Institute of Technology
THE EVOLUTION OF RNA POLYADENYLATION; DIFFERENT TAILS TELL DIFFERENT TALES
12:35 N. Jarrous, Hebrew University - Hadassah Medical School
ROLE OF THE HUMAN CATALYTIC RIBONUCLEOPROTEIN RNase P IN TRANSCRIPTION OF LARGE AND SMALL NONCODING RNA GENES
10:30 - 13:00 Parallel Session D-5: Drug development Hall E, Dan
Chairpersons: Y. Kloog, Z. Vogel
10:30 R. Satchi-Fainaro, Tel Aviv University
TARGETED ANTIANGIOGENIC THERAPY OF PROSTATE CANCER BONE METASTASES
10:55 M.B.H. Youdim, Technion-Israel Institute of Technology
WHY DO WE NEED MULTIMODAL NEUROPROTECTIVE AND NEURORESTORATIVE DRUGS TO TREAT ALZHEIMER'S AND PARKINSON'S DISEASES
11:20 A. Nudelman, Bar-Ilan University
DEVELOPMENT OF NOVEL PRODRUGS OF GABA AND TYPICAL ANTI-PSYCHOTIC AGENTS THAT EXHIBIT ANTIPSYCHOTIC EFFICACY WITH DIMINISHED EXTRAPYRAMIDAL EFFECTS
11:45 I. Benhar, Tel Aviv University
TARGETED DRUG-CARRYING PHAGE NANOPARTICLES
12:10 E. Heldman, Ben-Gurion University of the Negev
NANO-SIZE VESICLES FOR TARGETED DRUG DELIVERY TO THE BRAIN
12:35 Y. Yarden, Weizmann Institute of Science
PHARMACEUTICAL TARGETING OF GROWTH FACTOR RECEPTORS: MECHANISMS OF DRUG ACTION
WEDNESDAY, JANUARY 30, 2008 (continued)
10:30 - 13:00 Parallel Session D-6:
Instructive biomaterials for tissue engineering and regeneration Hall F, Dan
Chairpersons: S. Levenberg, S. Cohen
10:30 S. Levenberg, Technion-Israel Institute of Technology
EFFECT OF SCAFFOLD STIFFNESS ON MYOTUBE DIFFERENTIATION
10:55 J. Leor, Tel Aviv University and Chaim Sheba Medical Center
ENHANCING MYOCARDIAL MECHANICS: NON-CELLULAR APPROACHES
11:20 H. Rapaport, Ben-Gurion University of the Negev
DESIGNED ACIDIC-RICH PEPTIDE SCAFFOLDS FOR BONE TISSUE ENGINEERING
11:45 D. Baranes, Ben-Gurion University of the Negev
NEURAL TISSUE DEVELOPMENT ON BIOACTIVE AND INSTRUCTIVE ARAGONITE CRYSTALLINE BIOMATERIALS
12:10 D. Seliktar, Technion-Israel Institute of Technology
BIO-SYNTHETIC HYDROGELS FOR 3D CELL CULTURE
12:35 B. Geiger, Weizmann Institute of Science
FUNCTIONAL DISSECTION OF THE ADHESOME NETWORK
10:30 - 13:00 Parallel Session D-7: Systems biology and bioinformatics Hall G, Royal Beach
Chairpersons: N. Barkai, N. Balaban
10:30 E. Segal, Weizmann Institute of Science
TOWARD QUANTITATIVE MODELS FOR TRANSCRIPTIONAL REGULATION
10:55 A. Vaknin, Hebrew University
INTERACTING MOLECULAR SENSORS IN BACTERIA
11:20 Y. Meir, Ben-Gurion University of the Negev
ADAPTATION IN THE CHEMOTAXIS NETWORK OF E-Coli
11:45 N. Friedman, Weizmann Institute of Science
LIFE AT LOW COPY NUMBERS: STOCHASTICITY IN PROTEIN EXPRESSION AT THE SINGLE-MOLECULE LEVEL
12:10 E. Ruppin, Tel Aviv University
LARGE-SCALE RECONSTRUCTION AND PHYLOGENETIC ANALYSIS OF METABOLIC GROWTH ENVIRONMENTS
12:35 N. Balaban, Hebrew University
NON-GENETIC INDIVIDUALITY IN THE HOST-PHAGE INTERACTION
WEDNESDAY, JANUARY 30, 2008 (continued)
10:30 - 13:00 Parallel Session D-8: Functional organization of the nucleus Hall H, Royal Beach
Chairpersons: Y. Gruenbaum, A. Harel
10:30 E. Meshorer, Hebrew University
CHROMATIN DYNAMICS AND GLOBAL TRANSCRIPTION IN PLURIPOTENT EMBRYONIC STEM CELLS
10:55 Y. Shav-Tal, Bar-Ilan University
MEASURING THE EFFECTS OF CO-TRANSCRIPTIONAL SPLICING ON RNA POL II TRANSCRIPTION IN VIVO
11:20 A. Simon, Chaim Sheba Medical Center and Tel Aviv University
TRANSCRIPTIONAL REGULATION BY THE LAP2 FAMILY OF PROTEINS AT THE NUCLEAR ENVELOPE
11:45 S. Allon-Shalev, Ha'Emek Medical Center and Technion-Israel Institute of Technology
LAMIN A ASSOCIATED MEDICAL CONDITIONS - PLEIOTROPISM IN EXCELSIO, HUTCHINSON-GILFORD AS A REPRESENTING EXAMPLE
12:10 Y. Gruenbaum, Hebrew University
LAMINOPATHIC MUTATIONS INTERFERE WITH THE ASSEMBLY, LOCALIZATION AND DYNAMICS OF NUCLEAR LAMINS IN C. ELEGANS
12:35 M. Elbaum, Weizmann Institute of Science
REVERSIBILITY IN NUCLEOCYTOPLASMIC TRANSPORT
13:00 – 14:30 Lunch & Exhibition
14:30 - 17:00 Parallel Session E-1:
Nanobiology: the interplay between biology and nanoscience Hall A, Herods Forum
Chairpersons: D. Seliktar, E. Gazit
14:30 J.-P. Lellouche, Bar-Ilan University
MAGNETIC NANOSIZED COMPOSITES FOR THE DETECTION OF DNA HYBRIDIZATION - PLATFORM OPTIMIZATION USING THE COMBINATORIAL ENGINEERING OF FUNCTIONAL (polyCOOH) POLYPYRROLE/POLYCARBAZOLE-BASED POLYMERS
14:55 A. Freeman, Tel Aviv University
PROTEIN MEDIATED NANO-SCALE BIOTEMPLATING
15:20 M. Machluf, Technion-Israel Institute of Technology
NANOPARTICLE-DNA DELIVERY: FROM TARGETING TO EFFICIENT TRANSFECTION
15:45 D. Porath, Hebrew University
FROM BIO-INSPIRED SYSTEMS FOR NANOELECTRONICS TO PHYSICO-INSPIRED
TOOLS TO STUDY BIO-SYSTEMS
16:10 R. Naaman, Weizmann Institute of Science
SELF-ASSEMBLED MONOLAYERS OF BIOMOLECULES - A WINDOW INTO BIOPROCESSES AND TECHNOLOGY
16:35 L.A. Gheber, Ben-Gurion University of the Negev
NANOMEDICINE: NANOTECHNOLOGY FOR HEALTH
WEDNESDAY, JANUARY 30, 2008 (continued)
14:30 - 17:00 Parallel Session E-2: Gene and cell therapy Hall B, Herods Forum
Chairpersons: S. Ferber, Y. Shaul
14:30 Y. Shaul, Weizmann Institute of Science
HEPATITIS B VIRUS AS A TARGET AND AS A TOOL IN GENE THERAPY
14:55 D. Harats, Chaim Sheba Medical Center and Vascular Biogenics Ltd.
ENDOTHELIAL SPECIFIC HIF-1 ALPHA EXPRESSION
15:20 M.Y. Flugelman, Lady Davis Carmel Medical Center, Technion-Israel Institute of Technology and MGVS Ltd.
GENE-ACTIVATED CELLS FOR ENGINEERING BLOOD VESSELS - FROM BENCH TO BEDSIDE
15:45 S. Ferber, Chaim Sheba Medical Center and Tel Aviv University
USING ADULT TISSUES TO GENERATE NEW ORGANS: AUTOLOGOUS CELL REPLACEMENT THERAPY FOR DIABETES
16:10 Z. Eshhar, Weizmann Institute of Science
REDIRECTED T-CELLS FOR ADOPTIVE IMMUNOTHERAPY OF CANCER AND AUTOIMMUNE INFLAMMATION: LESSONS FROM TRANSGENESIS
16:35 A. Panet, Hebrew University - Hadassah Medical School
TARGETING OF VIRUSES TO SPECIFIC TISSUES AND APPLICATIONS IN GENE THERAPY
14:30 - 17:00 Parallel Session E-3: Host-pathogen interaction Hall C, Herods Forum
Chairpersons: S. Ankri, I. Rosenshine
14:30 S. Yaron, Technion-Israel Institute of Technology
NEW INSIGHTS ON THE INTERACTIONS BETWEEN THE FOOD BORN PATHOGENIC BACTERIA SALMONELLA TYPHIMURIUM AND PLANTS
14:55 D. Mirelman, Weizmann Institute of Science
TROPHOZOITES OF ENTAMOEBA HISTOLYTICA EPIGENETICALLY SILENCED IN SEVERAL GENES ARE VIRULENCE ATTENUATED
15:20 R. Dzikowski, Hebrew University - Hadassah Medical School
MECHANISMS UNDERLYING THE EPIGENETIC REGULATION OF ANTIGENIC VARIATION IN THE MALARIA PARASITE PLASMODIUM FALCIPARUM
15:45 Y. Litvak, Hebrew University
THE BEST DEFENSE IS A GOOD OFFENCE: BACTERIA DEPLOY GTPase
ACTIVATING PROTEINS
16:10 N.Y. Shpigel, Hebrew University
MYCOBACTERIUM AVIUM PARATUBERCULOSIS INVADES THE HUMAN GUT EPITHELIUM AND ELICITS LOCAL INFLAMMATORY RESPONSE - IMPLICATIONS FOR THE PATHOGENESIS OF CROHN'S DISEASE
16:35 I. Barash, Tel Aviv University
VIRULENCE MECHANISMS AND HOST SPECIFICITY OF GALL-FORMING PANTOEA AGGLOMERANS
WEDNESDAY, JANUARY 30, 2008 (continued)
14:30 - 17:00 Parallel Session E-4: Hormones and obesity:
an endocrine perspective of the obesity epidemics Hall D, Dan
Chairpersons: H. Kanety, H. Werner
14:30 T. Biron-Shental, Meir Medical Center and Tel Aviv University
THE THRIFTY PHENOTYPE HYPOTHESIS: DO METABOLIC SYNDROME AND DIABETES RESULT FROM INAPPROPRIATE MATERNAL-PLACENTAL-FETAL CONDITIONS?
14:55 M. Phillip, Schneider Children's Medical Center
NUTRITIONAL CATCH-UP
15:20 Y. Zick, Weizmann Institute of Science
IRS PROTEINS - KEY PLAYERS IN INSULIN SIGNAL TRANSDUCTION AND INSULIN RESISTANCE
15:45 E. Karnielly, Rambam Medical Center and Rappaport Faculty of Medicine, Technion
INFLAMMATION AND LIPOTOXICITY ON THE ROAD TO IMPAIRED GLUCOSE UPTAKE IN OBESITY
16:10 A. Rudich, Ben-Gurion University of the Negev
ADIPOSE TISSUES STRESSES IN OBESITY
16:35 H. Werner, Tel Aviv University
INSULIN-LIKE GROWTH FACTORS, OBESITY, AND CANCER
14:30 - 17:00 Parallel Session E-5: Bioimaging: from molecules to organisms Hall E, Dan
Chairpersons: B. Geiger, M. Barda-Saad
14:30 M. Barda-Saad, Bar-Ilan University
DYNAMICS OF SIGNALING COMPLEXES CRUCIAL FOR CYTOSKELETAL REORGANIZATION IN T CELLS
14:55 G. Shakhar, Weizmann Institute of Science
TWO PHOTON AND SECOND HARMONICS IMAGING OF THE IMMUNE SYSTEM
15:20 Z. Kam, Weizmann Institute of Science
IMAGE ACQUISITION AND UNDERSTANDING IN HIGH-THROUGHPUT HIGH-RESOLUTION (HTR) CELL-BASED SCREENING APPLICATIONS
15:45 Y. Garini, Bar-Ilan University
STUDYING THE GENOME ORGANIZATION IN THE NUCLEUS BY HIGH-RESOLUTION MICROSCOPY AND SINGLE MOLECULE METHODS
16:10 I. Tsarfaty, Tel Aviv University
CELLULAR AND ANIMAL MODELS FOR MOLECULAR IMAGING OF ONCOGENS
AND THEIR INHIBITION: Met AS A MODEL
16:35 N.E. Ziv, Technion-Israel Institute of Technology
LONG TERM OPTICAL AND ELECTROPHYSIOLOGICAL RECORDINGS OF IN-VITRO CORTICAL NEURONAL NETWORKS
WEDNESDAY, JANUARY 30, 2008 (continued)
14:30 - 17:00 Parallel Session E-6: Intracellular motility and cell division Hall F, Dan
Chairpersons: L. Gheber, M.E. Spira
14:30 Y. Kassir, Technion-Israel Institute of Technology
THE USE OF BUDDING-YEAST MEIOSIS AS A TOOL TO ELUCIDATE THE SPECIFIC FUNCTIONS OF MAMMALIAN CYCLIN DEPENDENT KINASES
14:55 L. Gheber, Ben-Gurion University of the Negev
KINESIN-5 FUNCTION DURING ANAPHASE SPINDLE ELONGATION
15:20 D. Raveh, Ben-Gurion University of the Negev
TUBULIN CHAPERONE E BINDS PROTEASOMES AND MICROTUBULES AND AFFECTS PROTEASOME FUNCTION UNDER STRESS
15:45 M. Brandeis, Hebrew University
CLEAVAGE FURROW INITIATION IN CYTOKINESIS IS REGULATED BY MICROTUBULES AND UBIQUITIN-MEDIATED DEGRADATION AND IS CELL CYCLE INDEPENDENT
16:10 A. Bershadsky, Weizmann Institute of Science
CELL ADHESION MECHANICS AND THE CYTOSKELETON: ROLES OF FORMIN MOLECULES
16:35 B. Aroeti, Hebrew University
THE BEST PIP SHOW IN TOWN: ENTEROPATHOGENIC ESCHERICHIA COLI CLUSTERS PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE TO MEDIATE ITS ADHERENCE AND ACTIN PEDESTAL BIOGENESIS
14:30 - 17:00 Parallel Session E-7: Molecular Biotechnology Hall G, Royal Beach
Chairpersons: J. Hirschberg, O. Shoseyov
14:30 J. Hirschberg, Hebrew University
PRODUCTION OF ASTAXANTHIN AND OTHER CAROTENOIDS BY THE BACTERIUM PARACOCCUS MARCUSII
14:55 Y. Reiter, Technion-Israel Institute of Technology
MOVING MOLECULAR IMMUNOLOGY AND ANTIBODY ENGINEERING INTO THERAPEUTICS
15:20 O. Shoseyov, Hebrew University and CollPlant Ltd.
INDUSTRIAL SCALE PRODUCTION OF RECOMBINANT HUMAN TYPE-I COLLAGEN IN TRANSGENIC TOBACCO PLANTS
15:45 E. Gazit, Tel Aviv University
SELF-ASSEMBLY OF PEPTIDES AND PROTEINS: FROM AMYLOID DISEASE TO NANOTECHNOLOGY
16:10 Y. Sha'altiel, Protalix
PRODUCTION OF PHARMACEUTICAL PROTEINS USING PLANT CELLS
WEDNESDAY, JANUARY 30, 2008
14:30 - 17:00 Parallel Session E-8: Immune response and regulation Hall H, Royal Beach
Chairpersons: R. Alon, R.N. Apte
14:30 N. Karin, Technion-Israel Institute of Technology
BENEFICIAL AUTOIMMUNITY REGULATES THE DYNAMICS OF INFLAMMATORY- AUTOIMMUNITY AND CANCER
14:55 C.J. Cohen, Bar-Ilan University
ENGINEERING THE IMMUNE RESPONSE AGAINST CANCER
15:20 Y. Reisner, Weizmann Institute of Science
TOLERANCE INDUCTION BY VETO CD8 T CELLS: MECHANISMS OF TCR INDEPENDENT KILLING
15:45 M. Baniyash, Hebrew University - Hadassah Medical School
CHRONIC INFLAMMATION-INDUCED IMMUNOSUPPRESSION: A DOUBLE EDGED SWORD IN CANCER AND AUTOIMMUNITY
16:10 B. Sredni, Bar-Ilan University
IMMUNOMODULATORY EFFECTS OF SMALL TELLURIUM MOLECULES; BASIC ASPECTS AND CLINICAL APPLICATIONS
16:35 Y. Mizrachi Nebenzahl, Soroka Medical Center and Ben-Gurion University of the Negev
THE NATURE OF THE PROTECTIVE INNATE AND ADAPTIVE IMMUNE RESPONSES TO
S. PNEUMONIAE
17:00 – 17:30 Coffee Break & Exhibition
17:30 - 20:00 Poster Session B Zones 1, 2 & 3
HAPPY-HOUR HOSTED BY ELDAN ELECTRONIC INSTRUMENTS CO. LTD.
WILL TAKE PLACE AT ALL THREE HOTELS
THURSDAY, JANUARY 31, 2008
08:00 - 10:30 Parallel Session F-1: Epigenetics Hall A, Herods Forum
Chairpersons: H. Cedar, Y. Bergman
08:00 S. Ankri, Technion-Israel Institute of Technology
CHARACTERIZATION OF AN UNUSUAL EPIGENETIC MACHINERY IN THE PROTOZOAN PARASITE ENTAMOEBA HISTOLYTICA
08:25 N. Friedman, Hebrew University
WHOLE-GENOME VIEW OF HISTONE DYNAMICS IN BUDDING YEAST
08:50 N. Ohad, Tel Aviv University
EVOLUTION OF PLANT EPIGENETIC MACHINERIES AND THEIR ROLE IN GENE IMPRINTING
09:15 S. Pradhan, New England Biolabs, Inc., USA
COORDINATED HISTONE AND DNA METHYLATION DURING REPLICATION IN MAMMALIAN CELLS
09:40 H. Cedar, Hebrew University
DNA REPLICATION TIMING IS CONTROLLED BY HISTONE MODIFICATION AT THE ORIGIN
08:00 - 10:50 Parallel Session F-2:
Basic biology and applications of stem cells Hall B, Herods Forum
Chairpersons: L. Gepstein, D. Zipori
08:00 B. Reubinoff, Hebrew University – Hadassah Medical Center
NEURAL DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS (hESCs) - MECHANISMS AND POTENTIAL APPLICATIONS
08:25 R. Eiges, Shaare Zedek Medical Center
MODELING FRAGILE X SYNDROME USING HUMAN EMBRYONIC STEM CELLS
08:50 L. Gepstein, Technion-Israel Institute of Technology
MYOCARDIAL REGENERATION USING HUMAN EMBRYONIC STEM CELLS
09:15 N. Askenazy, Schneider Children's Medical Center and Tel Aviv University
EVIDENCE OF NEOGENESIS OF INSULIN PRODUCING CELLS FROM ADULT STEM
CELLS IN VIVO
09:40 D. Zipori, Weizmann Institute of Science
AN ALTERNATIVE VIEW OF STEMNESS: THE STEM STATE THAT ENTAILS PLASTICITY, DEDIFFERENTIATION AND EPIGENETIC MODULATIONS
10:05 B. Dekel, Chaim Sheba Medical Center
ACCUMULATION OF MALIGNANT RENAL STEM CELLS IS ASSOCIATED WITH EPIGENETIC CHANGES IN NORMAL RENAL-PROGENITOR GENES
10:30 L. Gilboa, Weizmann Institute of Science
SOMA-GERM LINE INTERACTIONS CONTROL ADULT GERM LINE STEM CELL NUMBERS IN THE DROSOPHILA OVARY
THURSDAY, JANUARY 31, 2008 (continued)
08:00 - 10:30 Parallel Session F-3:
DNA dynamics: replication, recombination and repair Hall C, Herods Forum
Chairpersons: J. Shlomai, Z. Livneh
08:00 A. Hellman, Hebrew University - Hadassah Medical School
TOWARDS A GENETIC-EPIGENETIC SCREEN FOR COMMON HUMAN DISEASE GENES
08:25 J. Shlomai, Hebrew University - Hadassah Medical School
ENZYMATIC MECHANISM CONTROLS REDOX-MEDIATED PROTEIN-DNA INTERACTIONS AT THE MITOCHONDRIAL DNA REPLICATION ORIGIN
08:50 Z. Livneh, Weizmann Institute of Science
ERROR-PRONE DNA REPAIR IN MAMMALS: HOW CAN A MUTAGENIC PROCESS PREVENT CANCER
09:15 B. Kerem, Hebrew University
THE REGULATION OF CHROMOSOMAL INSTABILITY IN RESPONSE TO REPLICATION STRESS
09:40 M. Kupiec, Tel Aviv University
THE GENETIC CONTROL OF TELOMERE LENGTH
10:05 J. Stavans, Weizmann Institute of Science
SEX AND SENSITIVITY - THE (IN)FIDELITY OF DNA HOMOLOGOUS RECOMBINATION
08:00 - 10:30 Parallel Session F-4: Secretory pathways Hall D, Dan
Chairpersons: D. Cassel, S. Bar-Nun
08:00 J. Donaldson, NHLBI, NIH, USA
CLATHRIN-INDEPENDENT ENDOCYTOSIS: REGULATION BY MULTIPLE GTPases
08:25 M. Ehrlich, Tel Aviv University
Dab2: INTEGRATING THE REGULATION OF ENDOCYTOSIS AND CELL MATRIX INTERACTIONS
08:50 D. Neumann, Tel Aviv University
ERYTHROPOIETIN RECEPTOR: UNIQUE PROTEIN METABOLISM CONFERRED BY RECEPTOR DOMAINS
09:15 D. Cassel, Technion-Israel Institute of Technology
GOLGI ArfGAPs: MEMBRANE TARGETING AND INTERACTION WITH THE COPI TRAFFICKING SYSTEM
09:40 H. Abeliovich, Hebrew University
REGULATION OF MITOCHONDRIAL AUTOPHAGY IN SACCHAROMYCES CEREVISIAE
10:05 Z. Elazar, Weizmann Institute of Science
LC3 IS ESSENTIAL FOR p62/SQSTM1 RECRUITMENT INTO AUTOPHAGOSOMES
THURSDAY, JANUARY 31, 2008
08:00 - 10:30 Parallel Session F-5: Vascular biology and angiogenesis Hall E, Dan
Chairpersons: E. Keshet, G. Neufeld
08:00 R. Alon, Weizmann Institute of Science
FORCE REGULATED LFA-1-ICAM-1 INTERACTIONS IN LYMPHOCYTE CROSSING OF VASCULAR ENDOTHELIUM
08:25 E. Zelzer, Weizmann Institute of Science
THE FORMING LIMB SKELETON PATTERNS THE VASCULATURE VIA Sox9 REGULATION OF Vegf
08:50 G. Neufeld, Technion-Israel Institute of Technology
REGULATION OF ANGIOGENESIS BY SEMAPHORINS
09:15 I. Vlodavsky, Technion-Israel Institute of Technology
THE IMPACT OF HEPARANASE ON TUMOR METASTASIS, ANGIOGENESIS AND INFLAMMATION
09:40 M. Neeman, Weizmann Institute of Science
ENVIRONMENTAL STRESS AS A MODULATOR OF LYMPHATIC FUNCTION AND STRUCTURE
10:30 – 11:00 Coffee Break & Exhibition
11:00 - 13:00 Plenary 5: מדע וחברה: הכורח בניסויים בבעלי חיים Hall A, Herods Forum
יושבי ראש: אריה אלדר, חבר כנסת, אלכס צפרירי, מכון ויצמן למדע
11:00 רות ארנון, סגנית נשיא האקדמיה הלאומית למדעים
ניסויים בבע"ח הכרחיים לפיתוח תרופות
11:15 רמי רחמימוב, המדען הראשי, משרד הבריאות
האם הצעות החוק הפרטיות ביחס לניסויים בבע"ח מהוות איום על המחקר בישראל?
11:30 ערן דולב, מכללת תל-חי
גישה ערכית ואתית לניסויים בבע"ח
11:45 יאיר רייזנר, מכון ויצמן למדע
השתלת מוח עצם לחולים בלי תורם מתאים
12:00 איתן גלון, האוניברסיטה העברית בירושלים
עכברים מהונדסים: חשיבותם בחקר מחלות אדם וחיה לפיתוח תרופות ושיטות אבחון
12:15 חרמונה שורק, האוניברסיטה העברית בירושלים
עכברים מהונדסים כמודל לחקר מחלת אלצהיימר
12:30 הרב בנימין אלון, חבר כנסת
12:45 אריה אלדר, חבר כנסת