Program

Monday, Nov 26
Tuesday, Nov 27

08:30 Gathering and Coffee

08:45 Welcome adress

09:00 Defining immune cells Chair: Yair Reisner, Weizmann Institute of Science, Rehovot

09:00 Meinrad Busslinger IMP, Vienna Transcriptional control of B cell development

09:35 Yehudit Bergman Hebrew University, Jerusalem Allelic plasticity and commitment in the hematopoietic system

10:00 Ido Amit Weizmann Institute of Science, Rehovot Let's work together: What we learn from measuring genome wide binding dynamics of 40 TFs

10:25 Coffee break

11:00 Hans-Reimer Rodewald DKFZ, Heidelberg Pathways and lineage relationships in unperturbed hematopoiesis

11:35 Nir Friedman Weizmann Institute of Science, Rehovot Randomly made yet ordered: CD4 T cell receptor and functional repertoires

12:00 Orly Avni Bar Ilan University Medical School Tsfat Dual function of polycomb group proteins in differentiated T helper cells

12:25 Lunch break

13:45 Developmental Pathways Chair: Yoram Groner, Weizmann Institute of Science, Rehovot

13:45 Boris Reizis Columbia University, NY Molecular control of dendritic cell development and homeostasis

14:20 Wilfried Ellmeier Medical University, Institute of Immunology, Vienna Epigenetic and transcriptional control of T cell development and function •

14:55 Jakub Abramson Weizmann Institute of Science, Rehovot Molecular control of central tolerance

15:20 Coffee break

15:40 Ludger Klein LMU, Munich Thymic epithelium and central T cell tolerance

16:15 Micha Berger Lautenberg Center, Hebrew University, Jerusalem Activation of the Inactivation of T cells by the Novel Gene, Schlafen-2

16:40 Tzvee Lapidot Weizmann Institute of Science, Rehovot α-smooth muscle actin monocytes-macrophages preserve and protect primitive hematopoietic cells in the bone marrow via PGE2 signaling

08:45 Gathering and Coffee

09:00 Immune cell homeostasis, death & survival Chair: Ronen Alon, Weizmann Institute of Science, Rehovot

09:00 Klaus Rajewsky Max-Delbrueck Center, Berlin Germinal center-dependent and -independent B cell memory

09:35 Claudia Berek DRFZ, Berlin How plasma cells survive

10:10 Doron Melamed Technion, Rappaport Institute, Haifa Modification of B cell receptor signals alters fate decisions in B lineage cells

10:35 Coffee break

11:00 Facundo Batista LRI, Cancer Research UK, London Dynamic imaging of lymphocyte activation - from single molecule to living tissue

11:35 Boaz Tirosh Hebrew University, Jerusalem Synthetic lethality and functional compensation between the UPR and mTOR in plasma cell differentiation

12:00 Idit Shachar Weizmann Institute, Rehovot Molecular mechanisms regulating B cell survival in health and disease

12:25 Lunch break

13:45 Immune responses Chair: Yinon Ben-Neriah, Lautenberg Center, Hebrew University, Jerusalem

13:45 Robert Jack University of Greifswald IL-10 directs mouse monocyte differentiation in the infected peritoneum

14:20 Steffen Jung Weizmann Institute of Science, Rehovot Fate mapping monocytes and macrophages

14:45 Guy Shakhar Weizmann Institute, Rehovot To relocate or not? Career decisions of a dendritic cell

15:10 Coffee break

15:30 Dan Littman NYU Medical Center, New York Influence of the intestinal microbiota on immune system homeostasis

16:05 Eran Elinav Weizmann Institute of Science, Rehovot Neighborly relationship: cooperative regulation of metabolic homeostasis by the host and its microbiota

16:30 Ariel Munitz Tel Aviv University Molecular checkpoints in IL-4/IL-13-induced mucosal inflammation

13:10

14:15

14:30