• Session IV: Multi-domain and repeat protein folding
  • Co-chairs: Lila Gierasch and Abdussalam Azem
  • 08:30-09:10
    Lynne Regan, Yale University: Folding and function of repeat proteins
  • 09:10-09:50
    Susan Marqusee, Stanford University: Manipulating the protein energy landscape
  • 09:50-10:10
    Hema Chandra Kotamarthi, TIFR: Probing mechanical unfolding properties of SUMO-1 protein, a structural homologue of ubiquitin
  • 10:10-10:40
    Coffee break
  • 10:40-11:20
    Koby Levy, Weizmann Institute: Biophysical consequences of tethering in repeat, multi-domain and conjugated proteins
  • 11:20-12:00
    Doug Barrick, Johns Hopkins University: The use of repeat proteins to quantify cooperativity and parallel pathways in protein folding
  • 12:00-12:40
    Jane Clarke, University of Cambridge: Studies of the folding and misfolding of multidomain proteins with tandem homologous repeats
  • 12:40-14:00
  • Session V: Protein folding in the context of the cell
  • Co-chairs: Lynne Regan and Masha Niv
  • 14:00-14:40
    Lila Gierasch, University of Massachussets at Amherst: Exploring protein homeostasis in E. coli cells through experiment and computational modeling
  • 14:40-15:20
    Martin Gruebele, University of Illinois, Urbana: Protein dynamics in living cells
  • 15:20-15:40
    Tzachi Hagai, Weizmann Institute: Ubiquitin: not just a tag? A biophysical and evolutionary perspective on ubiquitination
  • 15:40-16:10
    Coffee break
  • 16:10-16:50
    Elizabeth Meiering, University of Waterloo: Synergies and snags in balancing folding and function of natural and designed beta-trefoil proteins
  • 16:50-17:10
    Shachi Gosavi, National Centre for Biological Sciences: Extracting the folding motif from the beta-trefoil proteins
  • 17:10-17:50
    Elizabeth Rhoades, Yale University: α-Synuclein: probing the conformations of a polymorphic membrane-binding protein
  • 19:00
    Departure for dinner in Old Jaffa