IMP/I-CORE Symposium on Molecular Machines

October 15, 2015
The David Lopatie Conference Center
Weizmann Institute of Science

Thursday 15th
09:00 Welcome Joel L. Sussman & Tim Clausen

Session "Machineries
09:10 The mechanobiology of cell adhesion: How are mechanical perturbations translated into biochemical signals.
Benjamin Geiger (WIS)
09:40 Revealing a bacterial version of the ubiquitin-proteasome system.
Débora Broch-Trentini (IMP)
10:10 Cellulosomes: Multienzyme machines for deconstruction of structural polysaccharides.
Ed Bayer (WIS)

10:40 Coffee Break

Session "Mechanisms"
11:10 Feedback Regulation in Proteasomal Degradation.
Ami Navon (WIS)
11:40 Structural and functional investigation of the protein arginine kinase McsB.
Marcin Suskiewicz (IMP)
12:10 Allostery in the chaperonin folding machine.
Amnon Horovitz (WIS)

12:40 Lunch

Session "Molecules"
14:00 Towards a better understanding of myosin folding and assembly.
Nina Franicevic (IMP)
14:30 The molecular basis for type I interferon activity.
Gideon Schreiber (WIS)
15:00 PDBwide identification of functional quaternary structures.
Emmanuel Levy (WIS)

15:30 Coffee Break

Session "and beyond"
16:00 Mechanism and regulation of the Hsp104 disaggregase
Tim Clausen (IMP)
16:30 Proteopedia a tool for Visualizing Molecular Machines
Joel L. Sussman (WIS)
18:30 Depart for Festive Dinner