My work at the Weizmann Institute of
Science
.
I work for the Brain Research
Center, Optical
Imaging Laboratory as a computer and electronics engineer, I am in charge of the
development of new computerized experimental set-ups for optical imaging. These set-ups
are used by the students in the lab as tools for functional brain mapping.
In the past few years I have been involved in the following projects:
- Disk Speed checking program.
- Acquisition of CCD data - A setup that is based on a CCD camera by FUJI Photo Film
HR Deltaron 1700 that takes up to 1700 frames per second and is used to to collect images that
are generated by voltage sensitive dyes. In this design, I had to do GPIB communication
under WinNT, do modification to the camera firmware (this was done in Z80 assembler), and
to developed a Heart Beat respiration controller which was based on a Microchip PIC 16C57 and implemented RS232 to
communicate with the PC.
- Acquisition of Video Data - This system is based on
a B&W video camera and a Differential Video Amplifier that enables us to see 1/1000
changes in the light reflected from live brain tissue. Such optical signals are smaller
than one gray level, but we needed to measure those signal with an 8 bit video digitizer.
Therefore I designed a differential video amplifier which amplifies the difference between
the incoming camera video signal from a reference video signal. This design included
Analog and Digital circuits. The digital part was made of two Altera EP610 EPLDs, one to control
video timing and the other to interface lab equipment to the printer port of the PC. The
computer system was based on an EISA IBM-PC that collected video frames into 64MB of RAM
and 10GB disk. I had to interface to the Image
IM-640 frame grabber (made by
)
and to write software in C to collect and analyze data. The software is written using MetaWare High C compiler running under PharLap 386 Dos Extender. In this system, we have also
integrated two other boards PIO-12 and CTM-05 made by
. I finished this project by helping to design a printed
circuit board which was passed on to a manufacturing company. In the differential
amplifier I also use components like Harris, HA-2405 PRAM Four
Channel Programmable Amplifiers, HA-2542 Wideband, High
Slew Rate, High Output Current Operational Amplifier and HA-5330 Very High Speed
Precision Monolithic Sample and Hold Amplifier.
- An EEG acquisition system that helped us look for functional borders
between different areas in human brain and was used in a study at a hospital during
surgery to remove a tumor. The system collect EEG signals using DAS-1602 A/D boards (made by
). In this project
I defined the setup, I wrote software that used the A/D board and defined noise
cancellation algorithms.
- Dye screening controller. This device is used by our chemist for checking
new dyes that she develops. This design is based on an Altera
EP610 EPLD and uses a Harris, HI-508 Analog multiplexer.
- Acquisition Watchdog timer - A PIC 16C54 RISC micro
controller (or 16C54
) based watchdog timer for long timeout periods. The microcontroller is made by
Arizona Microchip Inc.
- Respirator - Heart Beat Synchronization controller - A
PIC 16C57 RISC micro
controller based synchronization controller that communicate to a PC via RS232 for
selection of 4 synchronization modes and timing data. This project is done using
CCS PCB C compiler
- I have used a Burr-Brown , UAF42 - Universal Action
Filter as a 50Hz notch filter used for electrical recording of spikes collected from
neurons in vivo.
Chaipi Wijnbergen
Brain Research Center
Weizmann Institute of Science
Rehovot 76100
Israel.
email : chaipi@tohu0.weizmann.ac.il
URL: http://www.weizmann.ac.il/~chaipi
Tel: + 972 8 9343079
Fax: + 972 8 9344129