Thomas Deneux

Weizmann Institute of Science - Department of Neurobiology
P.O. Box 26 Rehovot 76100, Israel
tel: (+972)-8-934-2867
fax: (+972)-8-934-2438
email: firstname.lastname@weizmann.ac.il

Research


I am a postdoc in the experimental neurobiology laboratory of Amiram Grinvald. Our research project is both the development of experimental techniques in vivo and more particularly the understanding of the visual cortex.

PhD thesis


Hemodynamic Models: Investigation and Application to Brain Imaging Analysis [17MB]

After a first and second degree in mathematics, I did my PhD in a computer science laboratory involved in the analysis of human brain imaging data. I studied how to combine data acquired from Electroencephalography and functional MRI. I focused on the link between the physiological activities measured by these two techniques: the neuronal electrical activity and the hemodynamic activity (i.e. changes in blood flow, volume and oxygenation induced by the neuronal activity). I considered how to use hemodynamic models describing this link (namely, sets of differential equations), to improve the analysis of the data.

During this PhD, I also achieved some experiments in optical imaging on the awake monkey to question these models. This was a collaboration with the CNRS in Marseille. These experiments leaded to new methods to estimate the blood flow in the vessels.

Distinctions


1996 - Second price at the french national bachelor competition "Concours Général" in Mathematics

1996 - Silver medal at the International Mathematical Olympiad (Bombay) for position 82

2006 - Price for PhD thesis from the EADS Corporate Research Foundation (link)

Publications


Thomas Deneux, Olivier Faugeras Using nonlinear models in fMRI data analysis: Model selection and activation detection NeuroImage 2006

Ivo Vanzetta, Thomas Deneux, Guillaume Masson, Olivier Faugeras Cerebral blood flow recorded at high sensitivity in two dimensions using high resolution optical imaging Proceedings of the IEEE International Symposium on Biomedical Imaging 2006 (poster )

Thomas Deneux, Olivier Faugeras EEG-fMRI fusion of non-triggered data using Kalman filtering Proceedings of the IEEE International Symposium on Biomedical Imaging 2006 (presentation )

Ivo Vanzetta, Thomas Deneux, Stéphane Fischer, Olivier Faugeras, Amiram Grinvald and Guillaume Masson Sensory-evoked cerebral blood ow responses in the awake monkey recorded in large vascular networks at micro-vascular resolution Meeting of the Society for Neuroscience 2006

Ivo Vanzetta, Thomas Deneux, Guillaume Masson and Olivier Faugeras Linearity and non-linearity of sensory-evoked neuronal and hemodynamic responses in awake monkey V1 Human Brain Mapping 2006 (poster )

Thomas Deneux, Olivier Faugeras Physiological model selection in fMRI Human Brain Mapping 2006 (poster )

Thomas Deneux, Olivier Faugeras, Daniel J. Jacobsen and Lars Kai Hansen  Neural activity vs. fMRI : Parameters Estimation for the Balloon Model Human Brain Mapping 2004 (poster )

Oral communications


Modèles hémodynamiques: investigation en Optical Imaging et application à la fusion EEG-IRMf ACI Masses de Données presentation, october 2005 [2.7MB]

Modéliser la réponse hémodynamique: estimation des paramètres du Balloon Model presentation at the SHFJ-CEA Orsay, june 2004 [1MB]

Hemodynamics – non-linear state space : the Balloon Model Copenhagen Image and Signal Processing workshop, may 2004 [0.8MB]

Exposé de thèse (9 mai 2006) Hemodynamic Models: Investigation and Application to Analysis in Brain Imagery [3.2MB]

Candidature INRIA (mai 2006) [3.5MB] [2.6MB]

Software


Some useful Matlab functions (display 4D data, sending emails...)

Miscellaneous


link to personal page