Accumulations in the brain of the suppressor T-cells induced by treatment
with the immunomodulator Copolymer 1

Copolymer 1 (the drug Copaxone for the treatment of multiple sclerosis), developed by scientists of the Department of Immunology, exerts its effect by induction of specific suppressor T cells. Such cells (fluorescently labeled) can cross the blood brain barrier to form clusters, as illustrated in this mouse brain section. This leads to the release of the respective Th2 cytokines in the target organ, thus alleviating the pathological autoimmune processes.