Feigelson S, Grabovsky V, Winter E, Chen LL, Pepinsky RB, Yednock T, Yablonski D, Lobb R, Alon R (2001)
the Src Kinase P56(Lck) up Regulates Vla-4 Integrin Affinity - Implications For Rapid Spontaneous and Chemokine-Triggered t Cell Adhesion to Vcam-1 and Fibronectin.
Journal of Biological Chemistry,
276:13891-13901
Publications
- Dwir O, Kansas GS, Alon R (2001) Cytoplasmic Anchorage of l-Selectin Controls Leukocyte Capture and Rolling by Increasing the Mechanical Stability of the Selectin Tether. Journal of Cell Biology, 155:145-156
- Alon R (2001) Encephalitogenic Lymphoblast Recruitment to Resting Cns Microvasculature: a Natural Immunosurveillance Mechanism?. Journal of Clinical Investigation, 108:517-519
- Grabovsky V, Feigelson S, Chen C, Bleijs DA, Peled A, Cinamon G, Baleux F, Arenzana-Seisdedos F, Lapidot T, Van Kooyk Y, Lobb RR, Alon R (2000) Subsecond Induction of Alpha 4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 Under Flow Conditions. Journal of Experimental Medicine, 192:495-505
- Sigal A, Bleijs DA, Grabovsky V, Van Vliet SJ, Dwir O, Figdor CG, Van Kooyk Y, Alon R (2000) the Lfa-1 Integrin Supports Rolling Adhesions on Icam-1 Under Physiological Sheer Flow in a Permissive Cellular Environment. Journal of Immunology, 165:442-452
- Dwir O, Kansas GS, Alon R (2000) an Activated l-Selectin Mutant With Conserved Equilibrium Binding Properties But Enhanced Ligand Recognition Under Shear Flow. Journal of Biological Chemistry, 275:18682-18691
- Peled A, Grabovsky V, Habler L, Sandbank J, Arenzana-Seisdedos F, Petit I, Ben-Hur H, Lapidot T, Alon R (1999) The Chemokine Sdf-1 Stimulates Integrin-Mediated Arrest of Cd34(+) Cells on Vascular Endothelium Under Shear Flow. Journal of Clinical Investigation, 104:1199-1211
- Chen C, Mobley JL, Dwir O, Shimron F, Grabovsky V, Lobb RR, Shimizu Y, Alon R (1999) High Affinity Very Late Antigen-4 Subsets Expressed on t Cells Are Mandatory For Spontaneous Adhesion Strengthening But Not For Rolling on Vcam-1 in Shear Flow. Journal of Immunology, 162:1084-1095
- Dwir O, Shimron F, Chen C, Singer MS, Rosen SD, Alon R (1998) Glycam-1 Supports Leukocyte Rolling in Flow: Evidence For a Greater Dynamic Stability of l-Selectin Rolling of Lymphocytes Than of Neutrophils. Cell Adhesion and Communication, 6:349-370