Our lab studies cellular communication in the immune system with these objectives:

  • Keeping biomedical applications in mind
    • The lab addresses questions important for optimizing cancer immunotherapy: how tumor antigens are carried to draining lymph nodes, and how tumor cells evade destruction by infiltrating lymphocytes
    • The control of autoimmunity by Treg in inflammatory bowel disease
  • Observing complicated cellular networks - to be true to the complicated cellular milieu we follow interactions among multiple cell populations by using several channels simultaneously.
  • Preserving physiological conditions - we image live mice using the least intrusive microscopic methods to keep blood, lymph and neural connections intact.
  • Employing cutting-edge microscopic techniques - we use two-photon fluorescent microscopy and second harmonics generation, which are ideal for in vivo microscopy.