2018 Annual Meeting
Biochemical & Cellular Mechanisms of PTM Regulation
Post-translational modifications (PTMs) are a major mechanism by which protein function is determined. PTMs may alter both structure and function of proteins to affect their binding interactions, cellular localization and stability. However, with more than 200 different types of protein modifications, the complexity of the PTM network and the underlying principles of their regulation is still largely unexplored. Importantly, decoding the PTM code should provide novel insight on aberrations in PTM regulation in human diseases. To advance this important frontier the annual meeting of the ISBMB will focus on Cellular and Biochemical aspects of PTM regulation.