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Department of Molecular Cell Biology
 


Oren Schuldiner

Principal Investigator / Head of Group
Dept. of Molecular Cell Biology
Wolfson Building for Biological Research  
Room 504A
Weizmann Institute of Science
Rehovot 7610001, Israel
Office: +972-8-934-2769
Email: oren.schuldiner@weizmann.ac.il


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Research Possibilities

I am seeking highly motivated individuals who are interested in using Drosophila as a model to neuronal remodeling. Candidates should be hard-working, good at problem solving, innovative, and well-trained in at least one of these fields: genetics, neurobiology. A working knowledge of basic molecular cloning and experience with Drosophila is strongly preferred.

Interested candidates should email a statement indicating research interests, a CV, and contact info for three professional references to Dr. Oren Schuldiner at oren.schuldiner@weizmann.ac.il.

PhD students: Highly motivated graduate students are welcome. Please first apply to the Feinberg Graduate School. Following acceptance to FGS, please send a CV and contact info for 1-2 reference letters.
Rotation students: Highly motivated rotation students are always welcome.
Please contact Oren by mail. 

View current available positions.

Position Duration and Dates Description
Master's Rotation 1st, 2nd, 3rd Rotations Neuronal remodeling is an essential process used to sculpt the mature nervous system in vertebrates and invertebrates. One major mechanism is axon pruning in which neurons eliminate specific sections of their axons in a stereotypic manner. Not much is know about the molecular mechanisms that underlie this process. Defects in pruning may result in neurological conditions such as synesthesia or autism and the molecular mechanisms involved in axon pruning during development are also involved in axon fragmentation during neurodegenerative diseases such as Alzheimer's, Parkinson's and ALS. Therefore, uncovering the molecular mechanisms underlying axon pruning during development should increase our knowledge more broadly on axon fragmentation during development, disease and after injury. We are studying this process in the fly as it is an awesome genetic model organism with cutting edge techniques that enable us to mutate and visualize single neurons within a whole brain. We are looking for bright and enthusiastic rotation students to join and push forward one of our ongoing research projects. Looking forward to see you!