Zipori D, Bol S (1979).The Role of Fibroblastoid Cells and Macrophages From Mouse Bone Marrow in the in Vitro Growth Promotion of Haemopoietic Tumor Cells. Exp Hematol . ,7(4):206-218
Selected Publications
Pioneering studies on the role of the bone marrow stroma in regulation of normal and leukemic hemopoietic cells (references 1-5) that predicted the structure of the stem cell niche (reference 6)
- ZIPORI D, SASSON T. (1980).Adherent Cells From Mouse Bone-Marrow Inhibit the Formation of Colony Stimulating Factor (Csf) Induced Myeloid Colonies. Experimental Hematology. ,8(6):816-817
- ZIPORI D, SASSON T, FRENKEL A. (1981).Myelopoiesis in the Presence of Stromal Cells From Mouse Bone-Marrow .1. Monosaccharides Regulate Colony Formation. Experimental Hematology. ,9(6):656-662
- ZIPORI D, SASSON T. (1981).Myelopoiesis in the Presence of Stromal Cells From Mouse Bone-Marrow .2. Mechanism of Glucose Dependent Colony Formation. Experimental Hematology. ,9(6):663-673
- ZIPORI D, LEE F. (1988).Introduction of Interleukin-3 Gene Into Stromal Cells From the Bone-Marrow Alters Hematopoietic Differentiation But Does Not Modify Stem-Cell Renewal. Blood. ,71(3):586-596
- ZIPORI D. (1981).Cell-Interactions in the Bone-Marrow Micro-Environment - Role of Endogenous Colony-Stimulating Activity. Journal of Supramolecular Structure and Cellular Biochemistry. ,17(4):347-357
Derivation and characterization of long term cultured mesenchymal stromal cells (MSCs)
- ZIPORI D, FRIEDMAN A, TAMIR M, SILVERBERG D, MALIK Z. (1984).Cultured Mouse Marrow Cell-Lines - Interactions Between Fibroblastoid Cells and Monocytes. Journal of Cellular Physiology. ,118(2):143-152
- ZIPORI D, DUKSIN D, TAMIR M, ARGAMAN A, TOLEDO J, MALIK Z. (1985).Cultured Mouse Marrow Stromal Cell-Lines .2. Distinct Subtypes Differing in Morphology, Collagen Types, Myelopoietic Factors, and Leukemic-Cell Growth Modulating Activities. Journal of Cellular Physiology. ,122(1):81-90
Discovery of a stromal protein, activin A, as a possible therapeutic modality for multiple myeloma
- ZIPORI D, TAMIR M, TOLEDO J, OREN T. (1986).Differentiation Stage and Lineage-Specific Inhibitor From the Stroma of Mouse Bone-Marrow That Restricts Lymphoma Cell-Growth. Proceedings of the National Academy of Sciences of the United States of America. ,83(12):4547-4551
- BROSH N, STERNBERG D, HONIGWACHSSHAANANI J, LEE BC, SHAVTAL Y, TZEHOVAL E, SHULMAN LM, TOLEDO J, HACHAM Y, CARMI P, JIANG W, SASSE J, HORN F, BURSTEIN Y, ZIPORI D. (1995).The Plasmacytoma Growth Inhibitor Restrictin-p is an Antagonist of Interleukin-6 and Interleukin-11 - Identification as a Stroma-Derived Activin-a. Journal of Biological Chemistry. ,270(49):29594-29600
- Zauberman A, Lapter S, Zipori D (2001). Smad Proteins Suppress Ccaat/Enhancer-Binding Protein (c/Ebp) Beta- and Stat3-Mediated Transcriptional Activation of the Haptoglobin Promoter. Journal of Biological Chemistry. ,276(27):24719-24725
Studies leading to the stem state theory
- Barda-Saad Mira, Shav-Tal Yaron, Rozenszajn Arie Leon, Cohen Michal, Zauberman Ayelet, Karmazyn Asaf, Parameswaran Reshmi, Schori Hadas, Ashush Hagit, Ben-Nun Avraham, Zipori Dov (2002).The Mesenchyme Expresses t Cell Receptor Mrnas: Relevance to Cell Growth Control.. Oncogene. ,21(13):2029-36
- Shani N, Rubin-Lifshitz H, Peretz-Cohen Y, Shkolnik K, Shinder V, Cohen-Sfady M, Shav-Tal Y, Barda-Saad M, Zipori D. (2009).Incomplete t-Cell Receptor-Beta Peptides Target the Mitochondrion and Induce Apoptosis. Blood. ,113(15):3530-3541
- Zipori D (2004).Opinion - the Nature of Stem Cells: State Rather Than Entity. Nature Reviews Genetics. ,5(11):873-878
The role of toll-like receptors in regulation of mesencymal stromal cell functions
- Pevsner-Fischer M, Morad V, Cohen-Sfady M, Rousso-Noori L, Zanin-Zhorov A, Cohen S, Cohen IR, Zipori D. (2007).Toll-Like Receptors and their Ligands Control Mesenchymal Stem Cell Functions. Blood. ,109(4):1422-1432
Cellular plasticity of mesenchymal stromal cells under stress
- Ofer Shoshani, Hassan Massalha, Nir Shani, Sivan Kagan, Orly Ravid, Shalom Madar, Luba Trakhtenbrot, Dena Leshkowitz, Gideon Rechavi, Dov Zipori (2012).Polyploidization of Murine Mesenchymal Cells is Associated With Suppression of the Long Non-Coding Rna H19 and Reduced Tumorigenicity. Cancer Research. , in press:
Book Info
- Zipori D .Biology of stem cells and the molecular basis of the stem state. Humana Press (Springer), New York, Book (Monograph).
