Selected Relevant Publications (2004-2009)

• Fainaru, O., Woolf, E., Lotem, J., Yarmus, M., Brenner, O., Goldenberg, D., Negreanu, V., Bernstein, Y., Levanon, D., Jung, S. and Groner, Y. "Runx3 regulates mouse TGF-beta-mediated dendritic cell function and its absence results in airway inflammation". EMBO J. 23:969-979 (2004).
• Levanon, D. and Groner, Y. "Structure and regulated expression of mammalian RUNX genes". Oncogene.  23: 4211-4219 (2004).
• Brenner, O., Levanon, D., Negreanu, V., Golubkov, O., Fainaru, O., Woolf, E. and Groner, Y.
  "Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia". Proc. Natl. Acad. Sci . USA. 101: 16016-16021 (2004).
• Wang, X.P., Abert, T., James, M.J., Levanon, D., Groner, Y. and Thesleff, I. "Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth". J Dent Res. 84: 138-143 (2005).
• Fainaru, O., Shseyov, D., Hantisteanu, S. and Groner, Y. "Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease". Proc. Natl. Acad. Sci. USA. 102: 10598-10603 (2005).
• Marmigere, F., Montelius, A., Wegner, M., Groner, Y., Reichardt, L.F. and Ernfors, P. "The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons." Nat. Neurosci. 9: 180-187 (2006).
• Yarmus, M., Woolf, E., Bernstein, Y., Fainaru, O., Negreanu, V., Levanon, D. and Groner, Y. "Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3". Proc. Natl. Acad. Sci. USA. 103: 7384-7389 (2006).
• Raveh, E., Cohen, S., Levanon, D., Negreanu, V., Groner, Y. and Gat, U. "Dynamic expression of Runx1 in skin affects hair structure". Mech. Dev. 123: 842-850 (2006).
• Hinoi, E., Bialek, P., Chen, Y.T., Rached, M.T., Groner, Y., Behringer, R.R., Ornitz, D.M. and Karsenty, G. "Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium". Genes Dev. 20: 2937-2942 (2006).
• Djuretic, I.M., Levanon, D., Negreanu, V., Groner, Y., Rao, A. and Ansel, K.M. "Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells". Nat. Immunol. 8: 145-153 (2007).
• Woolf, E., Brenner, O., Goldenberg, D., Levanon, D. and Groner, Y. "Runx3 regulates dendritic epidermal T cell development". Dev. Biol. 303: 703-714 (2007).
• Fainaru, O., Shay, T., Hantisteanu, S., Goldenberg, D., Domany, E. and Groner, Y. "TGF beta-dependent gene expression profile during maturation of dendritic cells". Genes Immun. 8: 239-244 (2007).
• Pozner, A., Lottem, J., Xiao, C., Goldenberg, D., Brenner, O., Negreanu, V., Levanon, D., and Groner, Y. "Developmentally regulated promoter-switch transcriptionally controls Runx1 funaction during embryonic hematopoiesis". BMC Dev. Biol. 7:84, 1-19 (2007).
• Sullivan JC., Sher D., Eisenstein M., Shigesada K., Reitzel AM., Marlow H., Levanon D., Groner Y., Finnerty JR., Gat U. "The evolutionary origin of the Runx/CBFbeta transcription factors--studies of the most basal metazoans". BMC Evol. Biol. 8:228 (2008).
• Ben-Ami O., Pencovich N., Lotem J., Levanon D., Groner Y. "A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis". Proc. Natl. Acad. Sci. U S A. 106(1):238-243 (2009).
• Cruz-Guilloty F., Pipkin ME., Djuretic IM., Levanon D., Lotem J., Lichtenheld MG., Groner Y., Rao A. "Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs". J. Exp. Med. 206(1):51-59 (2009).
• Levanon D., and Groner Y. "Runx3-deficient mouse strains circa 2008: Resemblance and dissimilarly". Blood Cell. Mol. Dis. 43, 1-5 (2009).

Updated: 12/05/2010 16:46:25    Contact E-mail: Yoram.Groner@weizmann.ac.il