Publications

2018

  1. Salaroglio I. C., Gazzano E., Abdullrahman A., Mungo E., Castella B., Abd-elrahman G. E. F. A., Massaia M., Donadelli M., Rubinstein M., Riganti C. & Kopecka J. (2018). Increasing intratumor C/EBP- LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer.  Journal Of Experimental & Clinical Cancer Research. 37.  Abstract
  2. Kopecka J., Salaroglio I. C., Righi L., Libener R., Orecchia S., Grosso F., Milosevic V., Ananthanarayanan P., Ricci L., Capelletto E., Pradotto M., Napoli F., Di Maio M., Novello S., Rubinstein M., Scagliotti G. V. & Riganti C. (2018). Loss of C/EBP-beta LIP drives cisplatin resistance in malignant pleural mesothelioma.  Lung Cancer. 120:34-45.  Abstract
  3. Rubinstein M. (2018). Is Lgr4 essential for VSV- and VSV-G-pseudotyped lentiviral vector entry to cells?.  The journal of Biological chemistry. 293:(1)112-112.
  4. Rubinstein M. & Dvash E. (2018). Leukotrienes and kidney diseases.  Current Opinion in Nephrology and Hypertension. 27:(1)42-48.  Abstract

2017

  1. Salaroglio I. C., Panada E., Moiso E., Buondonno I., Provero P., Rubinstein M., Kopecka J. & Riganti C. (2017). PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy.  Molecular Cancer. 16.
  2. Wassermann Dozorets D. R. & Rubinstein M. (2017). C/EBP beta LIP augments cell death by inducing osteoglycin.  Cell Death & Disease. 8.  Abstract

2016

  1. Dvash E. & Rubinstein M. (2016). A surprising mediator of oxidative DNA damage.  Cell cycle (Georgetown, Tex.). 15:(7)869-70.

2015

  1. Dvash E., Har-Tal M., Barak S., Meir O. & Rubinstein M. (2015). Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage.  Nature Communications. 6:10112-10112.  Abstract
  2. Riganti C., Kopecka J., Panada E., Barak S. & Rubinstein M. (2015). The Role of C/EBP-beta LIP in Multidrug Resistance.  JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 107:(5)  Abstract

2014

  1. Garin-Shkolnik T., Rudich A., Hotamisligil G. S. & Rubinstein M. (2014). FABP4 Attenuates PPAR gamma and Adipogenesis and Is Inversely Correlated With PPARg in Adipose Tissues.  Diabetes. 63:(3)900-911.

2013

  1. Finkelshtein D., Werman A., Novick D., Barak S. & Rubinstein M. (2013). LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus.  Proceedings of the National Academy of Sciences of the United States of America. 110:(18)7306-7311.  Abstract

2012

  1. Shechter Y., Sasson K., Lev Goldman G. V., Rubinraut S., Rubinstein M. & Fridkin M. (2012). Newly Designed Modifier Prolongs the Action of Short-Lived Peptides and Proteins by Allowing Their Binding to Serum Albumin.  Bioconjugate Chemistry. 23:(8)1577-1586.  Abstract
  2. Novick D. & Rubinstein M. (2012). Ligand Affinity Chromatography, an Indispensable Method for the Purification of Soluble Cytokine Receptors and Binding Proteins.  Cytokine Protocols. 195-214.  Abstract

2011

  1. Zhang W., Lin M., Winesett A., Dhez O., Kilcoyne A. L., Ade H., Rubinstein M., Shafi K. V. P. M., Ulman A., Gersappe D., Tenne R., Rafailovich M., Sokolov J. & Frisch H. L. (2011). The use of functionalized nanoparticles as non-specific compatibilizers for polymer blends.  Polymers for Advanced Technologies. 22:(1)65-71.  Abstract

2010

  1. Meir O., Dvash E., Werman A. & Rubinstein M. (2010). C/EBP-beta Regulates Endoplasmic Reticulum Stress-Triggered Cell Death in Mouse and Human Models.  PLoS One. 5:(3)  Abstract
  2. Novick D., Elbirt D., Miller G., Dinarello C. A., Rubinstein M. & Sthoeger Z. M. (2010). High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein.  Journal of Autoimmunity. 34:(2)121-126.  Abstract

2009

  1. Novick D., Elbirt D., Dinarello C. A., Rubinstein M. & Sthoeger Z. M. (2009). Interleukin-18 Binding Protein in the Sera of Patients with Wegener's Granulomatosis.  Journal of Clinical Immunology. 29:(1)38-45.  Abstract

2008

  1. Werman A., Alkahe B., Dinarello C. A. & Rubinstein M. (2008). A role for intra-cellular interleukin-1alpha in antiviral defense.  Cytokine. 43:(3)307-307.  Abstract
  2. Werman A., Korba B. E., Alkahe B., Finkelshtein D., Bujanover S., Novick D., Vinocour E. & Rubinstein M. (2008). A soluble form of the LDL receptor inhibits hepatitis B virus replication in vitro.  Cytokine. 43:(3)249-249.  Abstract

2007

  1. Thompson S. R., Novick D., Stock C. J., Sanders J., Brull D., Cooper J., Woo P., Miller G., Rubinstein M. & Humphries S. E. (2007). Free interleukin (IL)-18 levels, and the impact of IL18 and IL18BP genetic variation, in CHD patients and healthy men.  ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 27:(12)2743-2749.  Abstract
  2. Novick D. & Rubinstein M. (2007). The tale of soluble receptors and binding proteins: From bench to bedside.  Cytokine & Growth Factor Reviews. 18:(6-May)525-533.  Abstract
  3. Rubinstein M. (2007). The purification and characterization of alpha interferons and related cytokine receptors - A personal account.  Cytokine & Growth Factor Reviews. 18:(6-May)519-524.  Abstract
  4. Spiegel A., Shivtiel S., Kalinkovich A., Ludin A., Netzer N., Goichberg P., Azaria Y., Resnick I., Hardan I., Ben-Hur H., Nagler A., Rubinstein M. & Lapidot T. (2007). Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34(+) cells through Wnt signaling.  Nature Immunology. 8:(10)1123-1131.  Abstract
  5. Naftali T., Novick D., Gabay G., Rubinstein M. & Novis B. (2007). Interleukin-18 and its binding protein in patients with inflammatory bowel disease during remissio and exacerbation.  Israel Medical Association Journal. 9:(7)504-508.  Abstract
  6. Hurgin V., Novick D., Werman A., Dinarello C. A. & Rubinstein M. (2007). Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1 alpha.  Cytokine. 39:(1)17-17.  Abstract
  7. Thompson S. R., Novick D., Stock C., Rubinstein M., Woo P., Humphries S. E. & Sanders J. (2007). Variation within IL18 but not IL18BP influences free IL-18 levels at baseline and during post-operative stress.  Atherosclerosis Supplements. 8:(1)52-52.  Abstract
  8. Birk R. Z. & Rubinstein M. (2007). Leptin restores plasma cholesterol, glucose and weight loss induced by IFN alpha treatment.  Biochemical and Biophysical Research Communications. 355:(3)626-631.  Abstract
  9. Hurgin V., Novick D., Werman A., Dinarello C. A. & Rubinstein M. (2007). Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1 alpha.  Proceedings of the National Academy of Sciences of the United States of America. 104:(12)5044-5049.  Abstract

2006

  1. Birk R. & Rubinstein M. (2006). IFN-alpha induces apoptosis of adipose tissue cells.  Biochemical and Biophysical Research Communications. 345:(2)669-674.  Abstract
  2. Novick D., Rubinstein M., Azam T., Rabinkov A., Dinarello C. & Kim S. (2006). Proteinase 3 is an IL-32 binding protein.  Proceedings of the National Academy of Sciences of the United States of America. 103:(9)3316-3321.  Abstract

2005

  1. Neumayr G., Ludwiczek O., Hoertnagl H., Pfister R., Mitterbauer G., Moschen A., Novick D., Rubinstein M. & Tilg H. (2005). The impact of prolonged strenuous endurance exercise on interleukin 18 and interleukin 18 binding protein in recreational cyclists.  International Journal of Sports Medicine. 26:(10)836-840.  Abstract
  2. Mazodier K., Marin V., Novick D., Farnarier C., Robitail S., Schleinitz N., Veit V., Paul P., Rubinstein M., Dinarello C., Harle J. & Kaplanski G. (2005). Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome.  Blood. 106:(10)3483-3489.  Abstract
  3. Shechter Y., Tsubery H., Mironchik M., Rubinstein M. & Fridkin M. (2005). Reversible PEGylation of peptide YY3-36 prolongs its inhibition of food intake in mice.  FEBS Letters. 579:(11)2439-2444.  Abstract
  4. Ludwiczek O., Kaser A., Novick D., Dinarello C., Rubinstein M. & Tilg H. (2005). Elevated systemic levels of free interleukin-18 (IL-18) in patients with Crohn's disease.  European Cytokine Network. 16:(1)27-33.  Abstract

2004

  1. Gutman G., Har-Toov J., Many A., Lessing J., Novick D., Rubinstein M. & Jaffa A. (2004). Second-trimester amniotic fluid and maternal serum interleukin-18 binding protein levels.  American Journal of Obstetrics and Gynecology. 191:(6)S152-S152.  Abstract
  2. Barkan D., Hurgin V., Dekel N., Amsterdam A. & Rubinstein M. (2004). Leptin induces ovulation in GnRH-deficient mice.  FASEB Journal. 18:(13)133-+.  Abstract
  3. Shevah O., Rubinstein M. & Laron Z. (2004). Molecular defects of the growth hormone receptor gene, including a new mutation, in Laron syndrome patients in Israel: Relationship between defects and ethnic groups.  Israel Medical Association Journal. 6:(10)630-633.  Abstract
  4. Kawashima M., Novick D., Rubinstein M. & Miossec P. (2004). Regulation of interleukin-18 binding protein production by blood and synovial cells from patients with rheumatoid arthritis.  Arthritis and Rheumatology. 50:(6)1800-1805.  Abstract
  5. Shevah O., Galli-Tsinopoulou A., Rubinstein M., Nousia-Arvanitakis S. & Laron Z. (2004). Classical phenotype of Laron syndrome in a girl with a heterozygous mutation and heterozygous polymorphism of the growth hormone receptor gene.  Journal Of Pediatric Endocrinology & Metabolism. 17:(3)371-374.  Abstract
  6. Tomiyama K., McNamara F., Clifford J., Kinsella A., Drago J., Fuchs S., Grandy D., Low M., Rubinstein M., Tighe O., Croke D., Koshikawa N. & Waddington J. (2004). Comparative phenotypic resolution of spontaneous D(2)-like and D(1)-like agonist-induced orofacial movement topographies in congenic mutants with dopamine D(2) vs. D(3) receptor "knockout".  Synapse. 51:(1)71-81.  Abstract

2003

  1. Azam T., Novick D., Bufler P., Yoon D., Rubinstein M., Dinarello C. & Kim S. (2003). Identification of a critical Ig-like domain in IL-18 receptor alpha and characterization of a functional IL-18 receptor complex.  Journal of Immunology. 171:(12)6574-6580.  Abstract
  2. Lonnemann G., Novick D., Rubinstein M. & Dinarello C. (2003). Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure.  Clinical Nephrology. 60:(5)327-334.  Abstract
  3. Feezor R., Oberholzer C., Baker H., Novick D., Rubinstein M., Moldawer L., Pribble J., Souza S., Dinarello C., Ertel W. & Oberholzer A. (2003). Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria.  Infection and Immunity. 71:(10)5803-5813.  Abstract
  4. Shevah O., Borrelli P., Rubinstein M. & Laron Z. (2003). Identification of two novel mutations in the human growth hormone receptor gene.  Journal of Endocrinological Investigation. 26:(7)604-608.  Abstract
  5. Gangemi S., Basile G., Merendino R., Minciullo P., Novick D., Rubinstein M., Dinarello C., Lo Balbo B. C., Franceschi C., Basili S., D' Urbano U. E., Davi G., Nicita-Mauro V. & Romano M. (2003). Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity?.  Experimental Gerontology. 38:(6)669-672.  Abstract
  6. Stuyt R., Kim S., Reznikov L., Fantuzzi G., Novick D., Rubinstein M., Kullberg B., van der Meer d. M. J., Dinarello C. & Netea M. (2003). Regulation of Staphylococcus epidermidis-induced IFN-7 in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF.  Cytokine. 21:(2)65-73.  Abstract
  7. Lonnemann G., Novick D., Rubinstein M., Passlick-Deetjen J., Lang D. & Dinarello C. (2003). A switch to high-flux Helixone (R) membranes reverses suppressed interferon-gamma production in patients on low-flux dialysis.  Blood Purification. 21:(3)225-231.  Abstract
  8. Dinarello C., Novick D., Rubinstein M. & Lonnemann G. (2003). Interleukin 18 and interleukin 18 binding protein: Possible role in immunosuppression of chronic renal failure.  Blood Purification. 21:(3)258-270.  Abstract
  9. Nolsoe R., Pociot F., Novick D., Rubinstein M., Kim S., Dinarello C. & Mandrup-Poulsen T. (2003). Mutation scan of a type 1 diabetes candidate gene - The human interleukin-18 binding protein gene.  Immunology Of Diabetes Ii: Pathogenesis From Mouse To Man. 1005:332-339.  Abstract

2002

  1. Hurgin V., Novick D. & Rubinstein M. (2002). The promoter of IL-18 binding protein: Activation by an IFN-gamma-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein beta.  Proceedings of the National Academy of Sciences of the United States of America. 99:(26)16957-16962.  Abstract
  2. Sandowski Y., Raver N., Gussakovsky E., Shochat S., Dym O., Livnah O., Rubinstein M., Krishna R. & Gertler A. (2002). Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain.  Journal of Biological Chemistry. 277:(48)46304-46309.  Abstract
  3. Ludwiczek O., Kaser A., Novick D., Dinarello C., Rubinstein M., Vogel W. & Tilg H. (2002). Plasma levels of interleukin-18 and interleukin-18 binding protein are elevated in patients with chronic liver disease.  Journal of Clinical Immunology. 22:(6)331-337.  Abstract
  4. Yatsiv I., Morganti-Kossmann M., Perez D., Dinarello C., Novick D., Rubinstein M., Otto V., Rancan M., Kossmann T., Redaelli C., Trentz O., Shohami E. & Stahel P. (2002). Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.  Journal of Cerebral Blood Flow and Metabolism. 22:(8)971-978.  Abstract
  5. Kaser A., Novick D., Rubinstein M., Siegmund B., Enrich B., Koch R., Vogel W., Kim S., Dinarello C. & Tilg H. (2002). Interferon-alpha induces interieukin-18 binding protein in chronic hepatitis C patients.  Clinical and Experimental Immunology. 129:(2)332-338.  Abstract
  6. Ariel A., Novick D., Rubinstein M., Dinarello C., Lider O. & Hershkoviz R. (2002). IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components.  Journal of Leukocyte Biology. 72:(1)192-198.  Abstract
  7. Shevah O., Nunez O., Rubinstein M. & Laron Z. (2002). Intronic mutation in the growth hormone receptor gene in a Peruvian girl with Laron syndrome.  Journal Of Pediatric Endocrinology & Metabolism. 15:(7)1039-1040.
  8. Kim S., Azam T., Novick D., Yoon D., Reznikov L., Bufler P., Rubinstein M. & Dinarello C. (2002). Identification of amino acid residues critical for biological activity in human interleukin-18.  Journal of Biological Chemistry. 277:(13)10998-11003.  Abstract

2001

  1. Zecchina G., Novick D., Rubinstein M., Barak V., Dinarello C. & Nagler A. (2001). Cutting edge communication - Interleukin-18 binding protein in acute graft versus host disease and engraftment following allogeneic peripheral blood stem cell transplants.  Journal Of Hematotherapy & Stem Cell Research. 10:(6)769-776.  Abstract
  2. Almog B., Gold R., Tajima K., Dantes A., Salim K., Rubinstein M., Barkan D., Homburg R., Lessing J., Nevo N., Gertler A. & Amsterdam A. (2001). Leptin attenuates follicular apoptosis and accelerates the onset of puberty in immature rats.  Molecular and Cellular Endocrinology. 183:(2-Jan)179-191.  Abstract
  3. Stuyt R., Netea M., Kim S., Novick D., Rubinstein M., Kullberg B., Van der Meer d. M. J. & Dinarello C. (2001). Differential roles of interleukin-18 (IL-18) and IL-12 for induction of gamma interferon by staphylococcal cell wall components and superantigens.  Infection and Immunity. 69:(8)5025-5030.  Abstract
  4. Novick D., Schwartsburd B., Pinkus R., Suissa D., Belzer I., Sthoeger Z., Keane W., Chvatchko Y., Kim S., Fantuzzi G., Dinarello C. & Rubinstein M. (2001). A novel IL-18BP ELISA shows elevated serum IL-18BP in sepsis and extensive decrease of free IL-18.  Cytokine. 14:(6)334-342.  Abstract
  5. Arazi T., Slutsky S., Shiboleth Y., Wang Y., Rubinstein M., Barak S., Yang J. & Gal-On A. (2001). Engineering zucchini yellow mosaic potyvirus as a non-pathogenic vector for expression of heterologous proteins in cucurbits.  Journal of Biotechnology. 87:(1)67-82.  Abstract
  6. Kim S., Azam T., Yoon D., Reznikov L., Novick D., Rubinstein M. & Dinarello C. (2001). Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein.  Proceedings of the National Academy of Sciences of the United States of America. 98:(6)3304-3309.  Abstract
  7. Cohen B., Barkan D., Levy Y., Goldberg I., Fridman E., Kopolovic J. & Rubinstein M. (2001). Leptin induces angiopoietin-2 expression in adipose tissues.  Journal of Biological Chemistry. 276:(11)7697-7700.  Abstract

2000

  1. Novick D., Nabioullin R., Ragsdale W., McKenna S., Weiser W., Garone L., Burkins C., Kim S., Rubinstein M., Tepper M. & Arulanandam A. (2000). The neutralization of type IIFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation.  Journal of Interferon and Cytokine Research. 20:(11)971-982.  Abstract
  2. Liu B., Novick D., Kim S. & Rubinstein M. (2000). Production of a biologically active human interleukin 18 requires its prior synthesis as pro-IL-18.  Cytokine. 12:(10)1519-1525.  Abstract
  3. Ben-Asher E., Chalifa-Caspi V., Horn-Saban S., Avidan N., Olender Z., Adato A., Glusman G., Safran M., Rubinstein M. & Lancet D. (2000). Harvesting the human genome: the Israeli perspective.  Israel Medical Association Journal. 2:(9)657-664.
  4. Reznikov L., Kim S., Westcott J., Frishman J., Fantuzzi G., Novick D., Rubinstein M. & Dinarello C. (2000). IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma.  Proceedings of the National Academy of Sciences of the United States of America. 97:(5)2174-2179.  Abstract
  5. Kim S., Eisenstein M., Reznikov L., Fantuzzi G., Novick D., Rubinstein M. & Dinarello C. (2000). Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18.  Proceedings of the National Academy of Sciences of the United States of America. 97:(3)1190-1195.  Abstract
  6. Vidal-Vanaclocha F., Fantuzzi G., Mendoza L., Fuentes A., Anasagasti M., Martin J., Carrascal T., Walsh P., Reznikov L., Kim S., Novick D., Rubinstein M. & Dinarello C. (2000). IL-18 regulates IL-1 beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.  Proceedings of the National Academy of Sciences of the United States of America. 97:(2)734-739.  Abstract

1999

  1. Barkan D., Jia H., Dantes A., Vardimon L., Amsterdam A. & Rubinstein M. (1999). Leptin modulates the glucocorticoid-induced ovarian steroidogenesis.  Endocrinology. 140:(4)1731-1738.  Abstract
  2. Novick D., Kim S., Fantuzzi G., Reznikov L., Dinarello C. & Rubinstein M. (1999). Interleukin-18 binding protein: A novel modulator of the Th1 cytokine response.  Immunity. 10:(1)127-136.  Abstract

1998

  1. Zelzer E., Levy Y., Kahana C., Shilo B., Rubinstein M. & Cohen B. (1998). Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1 alpha/ARNT.  EMBO Journal. 17:(17)5085-5094.  Abstract
  2. Rubinstein M., Dinarello C., Oppenheim J. & Hertzog P. (1998). Recent advances in cytokines, cytokine receptors and signal transduction.  Cytokine & Growth Factor Reviews. 9:(2)175-181.  Abstract
  3. Dinarello C., Novick D., Puren A., Fantuzzi G., Shapiro L., Muhl H., Yoon D., Reznikov L., Kim S. & Rubinstein M. (1998). Overview of interleukin-18: more than an interferon-gamma inducing factor.  Journal of Leukocyte Biology. 63:(6)658-664.  Abstract

1997

  1. Kim S., Cohen B., Novick D. & Rubinstein M. (1997). Mammalian type I interferon receptors consists of two subunits: IFNaR1 and IFNaR2.  Gene. 196:(2-Jan)279-286.  Abstract
  2. Ambrus J., Chadha S., Novick D., Rubinstein M., Gopalakrishnan B., Bernstein Z., Priore R. & Chadha K. (1997). Mechanism(s) of interferon inhibitory activity in blood from patients with AIDS and patients with lupus erythematosus with vasculitis.  Research Communications in Molecular Pathology and Pharmacology. 96:(3)255-265.  Abstract

1996

  1. Cohen B., Novick D. & Rubinstein M. (1996). Modulation of insulin activities by leptin.  Science. 274:(5290)1185-1188.  Abstract
  2. Gamus D., Romano A., Rubinstein M. & Savion N. (1996). Moderation of herpetic stromal keratitis by basic fibroblast growth factor.  Experimental Eye Research. 63:(1)1-7.  Abstract

1995

  1. DOMANSKI P., WITTE M., KELLUM M., Rubinstein M., HACKETT R., PITHA P. & COLAMONICI O. (1995). CLONING AND EXPRESSION OF A LONG FORM OF THE BETA-SUBUNIT OF THE INTERFERON ALPHA-BETA RECEPTOR THAT IS REQUIRED FOR SIGNALING.  Journal of Biological Chemistry. 270:(37)21606-21611.  Abstract
  2. Cohen B., Novick D., Barak S. & Rubinstein M. (1995). LIGAND-INDUCED ASSOCIATION OF THE TYPE-I INTERFERON RECEPTOR COMPONENTS.  Molecular and Cellular Biology. 15:(8)4208-4214.  Abstract
  3. Novick D., Cohen B., Tal N. & Rubinstein M. (1995). SOLUBLE AND MEMBRANE-ANCHORED FORMS OF THE HUMAN IFN-ALPHA/BETA RECEPTOR.  Journal of Leukocyte Biology. 57:(5)712-718.  Abstract

1994

  1. ULLRICH A., SURES I., DEGIDIO M., JALLAL B., POWELL T., Herbst R. H., DREPS A., AZAM M., Rubinstein M., NATOLI C., SHAWVER L., SCHLESSINGER J. & IACOBELLI S. (1994). THE SECRETED TUMOR-ASSOCIATED ANTIGEN 90K IS A POTENT IMMUNE STIMULATOR.  Journal of Biological Chemistry. 269:(28)18401-18407.  Abstract
  2. FISCHER D., Novick D., Cohen B. & Rubinstein M. (1994). ISOLATION AND CHARACTERIZATION OF A SOLUBLE FORM OF THE LDL RECEPTOR, AN INTERFERON-INDUCED ANTIVIRAL PROTEIN.  Proceedings Of The Society For Experimental Biology And Medicine. 206:(3)228-232.  Abstract
  3. Novick D., Cohen B. & Rubinstein M. (1994). THE HUMAN INTERFERON-ALPHA/BETA RECEPTOR - CHARACTERIZATION AND MOLECULAR-CLONING.  Cell. 77:(3)391-400.  Abstract

1993

  1. FISCHER D., Tal N., Novick D., Barak S. & Rubinstein M. (1993). AN ANTIVIRAL SOLUBLE FORM OF THE LDL RECEPTOR-INDUCED BY INTERFERON.  Science. 262:(5131)250-253.  Abstract
  2. Rubinstein M. (1993). PATENT CONCERNS.  Bio-Technology. 11:(4)420-420.

1992

  1. EDELBAUM O., STEIN D., HOLLAND N., GAFNI Y., Livneh O., Novick D., Rubinstein M. & Sela I. (1992). EXPRESSION OF ACTIVE HUMAN INTERFERON-BETA IN TRANSGENIC PLANTS.  Journal of Interferon Research. 12:(6)449-453.  Abstract
  2. Novick D., Cohen B. & Rubinstein M. (1992). SOLUBLE INTERFERON-ALPHA RECEPTOR MOLECULES ARE PRESENT IN BODY-FLUIDS.  FEBS Letters. 314:(3)445-448.  Abstract
  3. REITER Z., LOYTER A., NUSSBAUM O. & Rubinstein M. (1992). AN INDUCER OF NKCF (NK CYTOTOXIC FACTOR) RELEASE - LOCALIZATION ON TARGET-CELL MEMBRANE AND INITIAL CHARACTERIZATION.  Cellular Immunology. 142:(2)370-384.
  4. REITER Z., CHEN L., Revel M. & Rubinstein M. (1992). INTERLEUKIN-6 PROTECTS DUCTAL BREAST-CARCINOMA CELLS FROM MHC-UNRESTRICTED CELL-MEDIATED CYTOTOXICITY.  Journal of Interferon and Cytokine Research. 11:(3)175-181.  Abstract

1991

  1. REITER Z., REITER Y., FISHELSON Z., SHINITZKY M., KESSLER A., LOYTER A., NUSSBAUM O. & Rubinstein M. (1991). RESISTANCE TO NK-CELL-MEDIATED CYTOTOXICITY (IN K-562 CELLS) DOES NOT CORRELATE WITH CLASS-I MHC ANTIGEN LEVELS.  Immunobiology. 183:(2-Jan)23-39.  Abstract
  2. EDELBAUM O., SHER N., Rubinstein M., Novick D., Tal N., MOYER M., WARD E., RYALS J. & Sela I. (1991). 2 ANTIVIRAL PROTEINS, GP35 AND GP22, CORRESPOND TO BETA-1,3-GLUCANASE AND AN ISOFORM OF PR-5.  Plant Molecular Biology. 17:(1)171-173.
  3. YONISHROUACH E., Kimchi A. & Rubinstein M. (1991). THE ANTIPROLIFERATIVE EFFECT OF CYCLOSPORINE ON HEMATOPOIETIC AND LYMPHOBLASTOID CELL-LINES - COMMON MECHANISTIC ELEMENTS WITH INTERFERON-ALPHA.  Transplantation. 51:(6)1276-1282.  Abstract
  4. YONISHROUACH E., FISCHER D. & Rubinstein M. (1991). CYCLOSPORINE-A REGULATES THE EXPRESSION OF HLA-DR ON HUMAN MONOCYTES BY 2 DIFFERENT MECHANISMS.  Cellular Immunology. 134:(2)402-413.
  5. Novick D., ENGELMANN H., Revel M., Leitner O. & Rubinstein M. (1991). MONOCLONAL-ANTIBODIES TO THE SOLUBLE HUMAN IL-6 RECEPTOR - AFFINITY PURIFICATION, ELISA, AND INHIBITION OF LIGAND-BINDING.  Hybridoma. 10:(1)137-146.  Abstract
  6. Rubinstein M., Revel M., Novick D., MORY Y., FISCHER D., KADOURI A., BETZALEL M., ZEEVI M., HADAS E. & EREL Z. (1991). PRODUCTION, DOWNSTREAM PROCESSING AND CHARACTERIZATION OF PROTEINS FROM RECOMBINANT ANIMAL-CELLS - THE CASE OF HUMAN INTERFERON-BETA.  Biologicals From Recombinant Microorganisms And Animal Cells: Production And Recovery. 479-486.  Abstract
  7. MERIMSKY O., Rubinstein M., FISCHER D., Danon A. & CHAITCHIK S. (1991). PHARMACOKINETICS OF RECOMBINANT INTERFERON-ALPHA-C.  Cancer Chemotherapy and Pharmacology. 27:(5)406-408.  Abstract

1990

  1. YONISHROUACH E., SHINITZKY M. & Rubinstein M. (1990). A METHOD FOR PREPARING BIOLOGICALLY-ACTIVE AQUEOUS CYCLOSPORINE-A SOLUTIONS AVOIDING THE USE OF DETERGENTS OR ORGANIC-SOLVENTS.  Journal of Immunological Methods. 135:(2-Jan)147-153.  Abstract
  2. Harel A. (., FAINARU M., Rubinstein M., Tal N. & Schwartz M. (1990). FISH APOLIPOPROTEIN-A-I HAS HEPARIN BINDING-ACTIVITY - IMPLICATION FOR NERVE REGENERATION.  Journal of Neurochemistry. 55:(4)1237-1243.
  3. LAZARD D., Tal N., Rubinstein M., Khen M., Lancet D. & ZUPKO K. (1990). IDENTIFICATION AND BIOCHEMICAL-ANALYSIS OF NOVEL OLFACTORY-SPECIFIC CYTOCHROME-P-450IIA AND UDP-GLUCURONOSYL TRANSFERASE.  Biochemistry. 29:(32)7433-7440.
  4. Novick D., ENGELMANN H., Wallach D., Leitner O., Revel M. & Rubinstein M. (1990). PURIFICATION OF SOLUBLE CYTOKINE RECEPTORS FROM NORMAL HUMAN URINE BY LIGAND-AFFINITY AND IMMUNOAFFINITY CHROMATOGRAPHY.  Journal of Chromatography. 510:331-337.  Abstract
  5. REITER Z. & Rubinstein M. (1990). INTERLEUKIN-1-ALPHA AND TUMOR NECROSIS FACTOR-ALPHA PROTECT CELLS AGAINST NATURAL-KILLER CELL-MEDIATED CYTOTOXICITY AND NATURAL-KILLER CYTOTOXIC FACTOR.  Cellular Immunology. 125:(2)326-336.
  6. EDELBAUM O., ILAN N., GRAFI G., SHER N., STRAM Y., Novick D., Tal N., Sela I. & Rubinstein M. (1990). 2 ANTIVIRAL PROTEINS FROM TOBACCO - PURIFICATION AND CHARACTERIZATION BY MONOCLONAL-ANTIBODIES TO HUMAN BETA-INTERFERON.  Proceedings of the National Academy of Sciences of the United States of America. 87:(2)588-592.
  7. Wallach D., ADERKA D., Rubinstein M., ENGELMANN H., AVNI Y., SAROV I. & HOLTMANN H. (1990). MECHANISMS INVOLVED IN REGULATION OF THE RESPONSE TO TUMOR-NECROSIS-FACTOR - POSSIBLE ROLES FOR PROSTAGLANDIN PRODUCTION IN SENSITIZATION TO TNF EFFECTS AND FOR A SPECIFIC TNF-BINDING PROTEIN IN PROTECTION FROM THEM.  Tumor Necrosis Factor : Structure, Mechanism Of Action, Role In Disease And Therapy. 146-155.  Abstract
  8. Novick D., ENGELMANN H., Wallach D. & Rubinstein M. (1990). SOLUBLE CYTOKINE-RECEPTORS ARE PRESENT IN NORMAL HUMAN URINE.  Physiological And Pathological Effects Of Cytokines. 10:413-421.  Abstract
  9. ENGELMANN H., ADERKA D., HOLTMANN H., BRAKEBUSCH C., NOPHAR Y., Novick D., KEMPER O., Rubinstein M., AVNI Y., SAROV I. & Wallach D. (1990). SOLUBLE FORMS OF THE TNF RECEPTORS, PURIFIED FROM HUMAN URINE, INHIBIT TNF EFFECTS - ANTIBODIES AGAINST THE SOLUBLE RECEPTORS INDUCE TNF-LIKE EFFECTS.  Molecular And Cellular Biology Of Cytokines. 10:299-308.  Abstract

1989

  1. Novick D., ENGELMANN H., Wallach D. & Rubinstein M. (1989). SOLUBLE CYTOKINE RECEPTORS ARE PRESENT IN NORMAL HUMAN-URINE.  Journal of Experimental Medicine. 170:(4)1409-1414.
  2. ENGELMANN H., ADERKA D., Rubinstein M., ROTMAN D. & Wallach D. (1989). A TUMOR NECROSIS FACTOR-BINDING PROTEIN PURIFIED TO HOMOGENEITY FROM HUMAN-URINE PROTECTS CELLS FROM TUMOR NECROSIS FACTOR TOXICITY.  Journal of Biological Chemistry. 264:(20)11974-11980.
  3. Novick D., FISCHER D., REITER Z., Eshhar Z. & Rubinstein M. (1989). MONOCLONAL-ANTIBODIES TO THE HUMAN INTERFERON-GAMMA RECEPTOR - BLOCKING OF THE BIOLOGICAL-ACTIVITIES OF INTERFERON-GAMMA AND PURIFICATION OF THE RECEPTOR.  Journal of Interferon Research. 9:(3)315-328.
  4. Revel M., ZILBERSTEIN A., CHEN L., GOTHELF Y., BARASH I., Novick D., Rubinstein M. & MICHALEVICZ R. (1989). BIOLOGICAL-ACTIVITIES OF RECOMBINANT HUMAN IFN-BETA-2 IL-6 (ESCHERICHIA-COLI).  Annals of the New York Academy of Sciences. 557:144-156.
  5. Revel M., ZILBERSTEIN A., CHEN L., GOTHELF Y., BARASH I., Novick D., Rubinstein M. & MICHALEVICZ R. (1989). BIOLOGICAL-ACTIVITIES OF RECOMBINANT HUMAN IFN-BETA-2/IL-6 (ESCHERICHIA-COLI).  Regulation Of The Acute Phase And Immune Responses : Interleukin-6. 557:144-156.  Abstract
  6. Wallach D., HOLTMANN H., ADERKA D., Rubinstein M., AVNI Y., SAROV I. & ENGELMAN H. (1989). MECHANISMS WHICH TAKE PART IN REGULATION OF THE RESPONSE TO TUMOR NECROSIS FACTOR.  Lymphokine Research. 8:(3)359-363.

1988

  1. SHABO Y., Lotem J., Rubinstein M., Revel M., CLARK S., WOLF S., KAMEN R. & Sachs L. (1988). THE MYELOID BLOOD-CELL DIFFERENTIATION INDUCING PROTEIN MGI-2A IS INTERLEUKIN-6.  Blood. 72:(6)2070-2073.
  2. CHEN L., Novick D., Rubinstein M. & Revel M. (1988). RECOMBINANT INTERFERON-BETA-2 (INTERLEUKIN-6) INDUCES MYELOID DIFFERENTIATION.  FEBS Letters. 239:(2)299-304.
  3. REITER Z., FISCHER D. & Rubinstein M. (1988). THE PROTECTIVE EFFECT OF INTERFERON AGAINST NATURAL KILLING ACTIVITY IS NOT MEDIATED VIA THE EXPRESSION OF CLASS-I MHC ANTIGENS.  Immunology Letters. 17:(4)323-328.
  4. FISCHER D., Novick D., ORCHANSKY P. & Rubinstein M. (1988). 2 MOLECULAR-FORMS OF THE HUMAN INTERFERON-GAMMA RECEPTOR - LIGAND-BINDING, INTERNALIZATION, AND DOWN-REGULATION.  Journal of Biological Chemistry. 263:(6)2632-2637.

1987

  1. Revel M., ZILBERSTEIN A., RUGGIERI R., Rubinstein M. & CHEN L. (1987). AUTOCRINE INTERFERONS AND INTERFERON-BETA-2.  Journal of Interferon Research. 7:(5)529-536.
  2. Rubinstein M. (1987). MULTIPLE INTERFERON SUBTYPES - THE PHENOMENON AND ITS RELEVANCE.  Journal of Interferon Research. 7:(5)545-551.
  3. Novick D., ORCHANSKY P., Revel M. & Rubinstein M. (1987). THE HUMAN INTERFERON-GAMMA RECEPTOR - PURIFICATION, CHARACTERIZATION, AND PREPARATION OF ANTIBODIES.  Journal of Biological Chemistry. 262:(18)8483-8487.
  4. Rubinstein M., Novick D. & FISCHER D. (1987). THE HUMAN INTERFERON-GAMMA RECEPTOR SYSTEM.  Immunological Reviews. 97:29-50.

1986

  1. Goren T., FISCHER D. & Rubinstein M. (1986). HUMAN-MONOCYTES AND LYMPHOCYTES PRODUCE DIFFERENT MIXTURES OF ALPHA-INTERFERON SUBTYPES.  Journal of Interferon Research. 6:(4)323-329.
  2. FISCHER D. & Rubinstein M. (1986). HUMAN-MONOCYTES TUMORICIDAL ACTIVITY - THE ROLE OF INTERFERON-GAMMA AND BACTERIAL LIPOPOLYSACCHARIDE IN ITS STIMULATION, PRESERVATION AND DECAY.  Immunobiology. 172:(2-Jan)110-119.
  3. Goren T., FISCHER D. & Rubinstein M. (1986). PRIMING OF LEUKOCYTES SELECTIVELY INCREASES THE LEVEL OF SOME INTERFERON-ALPHA SUBTYPES AND NOT OTHERS.  Biochimica Et Biophysica Acta. 887:(1)80-85.
  4. Mizrachi Y., Rubinstein M., KIMHI Y. & Schwartz M. (1986). A NEUROTROPHIC FACTOR DERIVED FROM GOLDFISH BRAIN - CHARACTERIZATION AND PURIFICATION.  Journal of Neurochemistry. 46:(6)1675-1682.
  5. MORY Y., BENBARAK J., SEGEV D., Cohen B., Novick D., FISCHER D., Rubinstein M., KARGMAN S., ZILBERSTEIN A., VIGNERON M. & Revel M. (1986). EFFICIENT CONSTITUTIVE PRODUCTION OF HUMAN IFN-GAMMA IN CHINESE-HAMSTER OVARY CELLS.  Dna-A Journal Of Molecular & Cellular Biology. 5:(3)181-193.
  6. ORCHANSKY P., Rubinstein M. & FISCHER D. (1986). THE INTERFERON-GAMMA RECEPTOR IN HUMAN-MONOCYTES IS DIFFERENT FROM THE ONE IN NONHEMATOPOIETIC CELLS.  Journal of Immunology. 136:(1)169-173.
  7. Rubinstein M. & ORCHANSKY P. (1986). THE INTERFERON RECEPTORS.  Crc Critical Reviews In Biochemistry. 21:(3)249-275.

1985

  1. ROSENBERG H., MADAR Z., GERTLER A., Rubinstein M. & BINO T. (1985). THE FATE OF [I-125]-LABELED HUMAN LEUKOCYTE-DERIVED ALPHA INTERFERON IN THE RAT.  Journal of Interferon Research. 5:(1)121-127.

1984

  1. CHERNAJOVSKY Y., MORY Y., CHEN L., MARKS Z., Novick D., Rubinstein M. & Revel M. (1984). EFFICIENT CONSTITUTIVE PRODUCTION OF HUMAN FIBROBLAST INTERFERON BY HAMSTER-CELLS TRANSFORMED WITH THE IFN-BETA-1 GENE FUSED TO AN SV40 EARLY PROMOTER.  Dna-A Journal Of Molecular & Cellular Biology. 3:(4)297-308.
  2. FINEL M., Rubinstein M. & Pick U. (1984). PREPARATION OF AN EPSILON-DEFICIENT CHLOROPLAST COUPLING FACTOR-I HAVING A HIGH ATPASE ACTIVITY.  FEBS Letters. 166:(1)85-89.
  3. FRIEDLANDER J., FISCHER D. & Rubinstein M. (1984). ISOLATION OF 2 DISCRETE HUMAN INTERFERON-GAMMA (IMMUNE) SUBTYPES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY.  Analytical Biochemistry. 137:(1)115-119.
  4. ORCHANSKY P., Novick D., FISCHER D. & Rubinstein M. (1984). TYPE-I AND TYPE-II INTERFERON RECEPTORS.  Journal of Interferon Research. 4:(2)275-282.

1983

  1. Novick D., Eshhar Z., FISCHER D., FRIEDLANDER J. & Rubinstein M. (1983). MONOCLONAL-ANTIBODIES TO HUMAN INTERFERON-GAMMA - PRODUCTION, AFFINITY PURIFICATION AND RADIOIMMUNOASSAY.  EMBO Journal. 2:(9)1527-1530.
  2. Novick D., Eshhar Z., GIGI O., MARKS Z., Revel M. & Rubinstein M. (1983). AFFINITY-CHROMATOGRAPHY OF HUMAN FIBROBLAST INTERFERON (IFN-BETA 1) BY MONOCLONAL-ANTIBODY COLUMNS.  Journal of General Virology. 64:(APR)905-910.
  3. Goren T., Kapitkovsky A., Kimchi A. & Rubinstein M. (1983). HIGH AND LOW POTENCY INTERFERON-ALPHA SUBTYPES INDUCE (2'-5') OLIGOADENYLATE SYNTHETASE WITH SIMILAR EFFICIENCY.  Virology. 130:(2)273-280.
  4. FISCHER D. & Rubinstein M. (1983). SPONTANEOUS PRODUCTION OF INTERFERON-GAMMA AND ACID-LABILE INTERFERON-ALPHA BY SUBPOPULATIONS OF HUMAN MONONUCLEAR-CELLS.  Cellular Immunology. 81:(2)426-434.

1982

  1. Novick D., Eshhar Z. & Rubinstein M. (1982). MONOCLONAL-ANTIBODIES TO HUMAN ALPHA-INTERFERON AND THEIR USE FOR AFFINITY-CHROMATOGRAPHY.  Journal of Immunology. 129:(5)2244-2247.
  2. Fellous M., NIR U., Wallach D., MERLIN G., Rubinstein M. & Revel M. (1982). INTERFERON-DEPENDENT INDUCTION OF MESSENGER-RNA FOR THE MAJOR HISTOCOMPATIBILITY ANTIGENS IN HUMAN-FIBROBLASTS AND LYMPHOBLASTOID-CELLS.  Proceedings Of The National Academy Of Sciences Of The United States Of America-Biological Sciences. 79:(10)3082-3086.
  3. Rubinstein M. (1982). PURIFICATION AND STRUCTURAL-ANALYSIS OF INTERFERON.  PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES. 299:(1094)39-50.
  4. Rubinstein M. (1982). THE STRUCTURE OF HUMAN INTERFERONS.  Biochimica Et Biophysica Acta. 695:(1)5-16.
  5. ORCHANSKY P., Rubinstein M. & Sela I. (1982). HUMAN INTERFERONS PROTECT PLANTS FROM VIRUS-INFECTION.  Proceedings Of The National Academy Of Sciences Of The United States Of America-Biological Sciences. 79:(7)2278-2280.

1977

  1. Shechter Y., Rubinstein M. & Patchornik A. (1977). SELECTIVE COVALENT BINDING OF METHIONYL-CONTAINING PEPTIDES AND PROTEINS TO WATER INSOLUBLE POLYMERIC REAGENT AND THEIR REGENERATION.  Biochemistry. 16:(7)1424-1430.

1976

  1. Rubinstein M., Shechter Y. & Patchornik A. (1976). COVALENT CHROMATOGRAPHY - ISOLATION OF TRYPTOPHANYL CONTAINING PEPTIDES BY NOVEL POLYMERIC REAGENTS.  Biochemical and Biophysical Research Communications. 70:(4)1257-1263.

1975

  1. Rubinstein M. & Patchornik A. (1975). POLY(3,5-DIETHYLSTYRENE) SULFONYL CHLORIDE - NEW REAGENT FOR INTERNUCLEOTIDE BOND SYNTHESIS.  Tetrahedron. 31:(13-1)1517-1519.
  2. Shechter Y., Rubinstein M., BECKER R. & BOHAK Z. (1975). MODULATION OF ENZYMIC ACTIVITY OF CHICKEN PEPSIN BY COVALENT MODIFICATION OF ITS SINGLE - SH-GROUP.  FEBS Journal. 58:(1)123-131.
  3. Rubinstein M., AMIT B. & Patchornik A. (1975). USE OF A LIGHT-SENSITIVE PHOSPHATE PROTECTING GROUP FOR SOME MONONUCLEOTIDE SYNTHESES.  Tetrahedron Letters. (17)1445-1448.
  4. Rubinstein M. & Patchornik A. (1975). NOVEL METHOD FOR PHOSPHODIESTER AND INTERNUCLEOTIDE BOND SYNTHESIS.  Tetrahedron. 31:(17)2107-2110.