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Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YLR274W
    below threshold
    16.83
  • N' NOP1pr-GFP in SD
    YLR274W
    nucleus
    53.3269
  • N' TEF2pr-mCherry in SD
    noimage.png
    missing
    0
  • N' NATIVEpr-GFP in SD
    noimage.png
    missing
    0
  • N' TEF2pr-VC and Cyto-VN in SD
    noimage.png
    #N/A
    0
  • C’ GFP library in SD+DTT 
    YLR274W
    cytosol
    15.77
    0.93
    No
  • C’ GFP library in SD+H2O2
    YLR274W
    cytosol
    16.89
    1
    No
  • C’ GFP library in Starvation Media
    YLR274W
    cytosol
    N/A
    N/A
    Yes
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    below threshold
  • C’ GFP library on the background of CCT mutant
    noimage.png
    below threshold
    16.2546
    0.965319
    No
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