Neural Circuits

The neuron is the basic element of brain function. However, neurons do not act singly – rather, they act through complex yet coherent neural circuits and network, in order to generate sensory perceptions, actions, memories, thoughts.  Although the end-goals of different neural circuits are highly diverse, their structure is often surprisingly similar across different brain regions and animal species – which suggests that there are some elusive common principles that we need to understand about the basic operation of neural circuits, in terms of their structure and in terms of the neural code.  Such an elucidation requires intense cooperation between experimentalists and theorists.

 

Understanding the design and function of neural circuits - requires a diversity of approaches, and their combination. Coming from a variety of backgrounds, such as biology, physics, mathematics and computer science, engineering, and psychology – we develop and apply novel approaches to study neural circuits.  We combine extracellular and intracellular neural recording; imaging techniques spanning all scales from sub-cellular calcium imaging to whole-brain functional magnetic resonance imaging; and modern anatomical techniques. These are being complemented by theoretical studies of large-scale neuronal ensembles.  The questions that are being addressed range from studies of active-sensing systems, through neural codes of learning and memory, and ending with the neural basis of individual and group behaviors. 

 

Related Groups

  • Ahissar
  • Grinvald
  • Lampl
  • Malach
  • Paz
  • Schneidman
  • Segal
  • Tsodyks
  • Ulanovsky