March 02, 2015

  • Date:01SundayMarch 2015

    Mixing, stratification, and the spring phytoplankton bloom: Sverdrup’s critical depth revisited

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    Time
    11:00
    Location
    Sussman Family Building for Environmental Sciences
    M. Magaritz Seminar Room
    Lecturer
    Amatzia Genin
    H. Steinitz Marine Biological Laboratory The Hebrew University of Jerusalem
    Organizer
    Department of Earth and Planetary Sciences
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    AbstractShow full text abstract about The spring phytoplankton bloom is a major, extensively studi...»
    The spring phytoplankton bloom is a major, extensively studied phenomenon in temperate and high latitude seas. Much less information isavailable on blooms in subtropical oligotrophic seas, where the water column is usually stratified. Yet, even in temperate seas the processes determining phytoplankton dynamics during the mixed-layer deepening and the factors triggering the initiation of the bloom are controversial. Here we use long-term measurements of chlorophyll concentration, nutrients, mixed-layer depth and grazing rates to examine the validity of three bloom-initiation processes for the Gulf of Aqaba (northern Red Sea): the Critical Depth Hypothesis, the Dilution-Recoupling Hypothesis, and the Critical Turbulence Hypothesis. The Gulf is a unique water body in the subtropics, where convective mixing during winter reaches hundreds of meters in depth, leading to conspicuous spring blooms. Here we show that neither the critical depth mechanism nor the dilution-recoupling hypothesis explain the phytoplankton dynamics during the winter and spring in the Gulf. Instead, our findings indicate that this dynamics is governed by the interplay between three main processes: (1) nutrient-driven primary production in the upper, illuminated layer; (2) physical ‘homogenization’ of phytoplankton by convective mixing; and (3) accumulation of phytoplankton in the upper layer after the termination of sea-surface cooling. The latter mechanism is responsible for the onset and magnitude of the spring bloom.

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  • Date:01SundayMarch 2015

    Swap-N-Tag: a new tool for systematic characterization of yeast proteins

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    Time
    13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Uri Weill
    Maya Schuldiner's group, Dept. of Molecular Genetics
    Organizer
    Life Sciences
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    Lecture
  • Date:02MondayMarch 2015

    Computers and Molecules

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    Time
    08:30 - 17:00
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Chairperson
    Ehud Shapiro
    Contact
    Conference
  • Date:02MondayMarch 2015

    Preleukemia the normal side of cancer

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    Time
    11:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Dr. Liran Shlush
    Princess Margaret Cancer Center Toronto, Canada
    Organizer
    Department of Systems Immunology
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    Lecture
  • Date:02MondayMarch 2015

    "Learning from microbes to develop a catalyst for efficient conversion of methane to methanol under ambient conditions"

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    Time
    11:00 - 12:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Sunney I. Chan
    Institute of Chemistry, Academia Sinica, Taiwan
    Organizer
    Faculty of Chemistry
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    Colloquia
  • Date:03TuesdayMarch 2015

    Origin and composition of lipid droplets from Dunaliella

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    Time
    11:15
    Location
    Ullmann Building of Life Sciences
    Aharon Katzir Hall
    Lecturer
    Dr. Lital Davidi
    Postdoc Fellow at Prof. Edward A. Bayer's lab., PHD at Prof. Uri Pick's lab., Biological Chemistry Dept., WIS
    Organizer
    Department of Plant and Environmental Sciences
    Contact
    Lecture
  • Date:03TuesdayMarch 2015

    COMT*DYSBINDIN-1 CONCOMITANT REDUCTION PRODUCE SCHIZOPHRENIA-LIKE PHENOTYPES CONVERGING ON DOPAMINE PATHWAYS

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    Time
    12:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Dr. Francesco Papaleo
    Dept of Neuroscience and Brain Technologies,Istituto Italiano di Tecnologia, Genova
    Organizer
    Department of Brain Sciences
    Contact
    AbstractShow full text abstract about The etiology of schizophrenia is complex and largely unknown...»
    The etiology of schizophrenia is complex and largely unknown, but consistent findings report a strong genetic component. While several potential schizophrenia-susceptibility genes have been identified, effect sizes are very small and replication is inconsistent, likely because of the complexity of human polymorphisms, genetic and clinical heterogeneity and the potential uncontrollable impact of gene-gene and gene-environment interactions. In this context, mutant mice bearing targeted mutations of schizophrenia-susceptibility genes are unique tools to elucidate the neurobiological basis of this devastating disorder.
    Using COMT*dysbindin-1 double mutant mice, we investigated the COMT*dysbindin-1 gene-gene interacting effects in the expression of rodents’ correlates of schizophrenia-relevant behavioral abnormalities. A major focus of our work is centered on how to dissect higher order cognitive functions in mice with high translational validity to human studies.
    In particular, in contrast to single genetic modifications, the combined decreased activity of both COMT and dysbindin-1 produced marked working memory, recency memory and attentional set-shifting deficits, and amphetamine supersensitivity; all abnormalities ascribed as mice’ correlates of schizophrenia-like symptoms. Based on this, we found evidence of the same non-linear genetic interaction in prefrontal cortical function in humans. Finally, to disentangle how COMT*dysbindin-1 interaction might converge in dopaminergic signaling, we measured in these double mutant mice dopamine levels in the PFC and dorsal striatum by in vivo microdialysis. Interestingly, concomitant COMT*dysbindin-1 reduction diminished dopamine levels in PFC and striatum, while amphetamine-evoked dopamine increase was attenuated in the PFC but exacerbated in the striatum. These findings illustrate a clinically relevant experimental animal model based on a predicted epistatic interaction of two schizophrenia-susceptibility genes and unravel interesting genetic mechanisms in the etiology of this mental illness.
    Lecture
  • Date:03TuesdayMarch 2015

    "Nucleosome dynamics studied by computer simulation and single molecule spectroscopy"

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    Time
    14:00
    Location
    Helen and Milton A. Kimmelman Building
    Dov Elad Room
    Lecturer
    Prof. Jorg Langowski
    German Cancer Research Center (DKFZ)
    Organizer
    Department of Chemical and Structural Biology
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    Lecture
  • Date:03TuesdayMarch 2015

    Molecular Neuroscience Forum Seminar

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    Time
    15:00 - 16:00
    Title
    Interactions between nervous and vascular systems in the CNS
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Chenghua Gu
    Harvard University
    Organizer
    Department of Biomolecular Sciences
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    Lecture
  • Date:03TuesdayMarch 2015

    The Interface of Science and Policy

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    Time
    15:00 - 16:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Drory Auditorium
    Lecturer
    Dimitri Kusnezov
    Chief Scientist, US Department of Energy, National Nuclear Security Administration
    Organizer
    Department of Particle Physics and Astrophysics
    Contact
    DetailsShow full text description of 14:45 - Light Refreshments...»
    14:45 - Light Refreshments
    AbstractShow full text abstract about Time-urgent policy decisions are increasingly benefiting fro...»
    Time-urgent policy decisions are increasingly benefiting from the scientific assessments of risks and outcomes. However the ability to inject science into decision processes can be haphazard, requiring awareness of potential tools and involvement in the policy decisions. I hope to provide some insight on how science is drawn into decisions through a series of examples including the Fukushima Daiichi accident and aircraft safety to the Gulf oil spill and Ebola.
    Lecture
  • Date:03TuesdayMarch 2015

    The Interface of Science and Policy

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    Time
    15:00 - 16:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Drory Auditorium
    Lecturer
    Dimitri Kusnezov
    Chief Scientist, US Department of Energy, National Nuclear Security Administration
    Organizer
    Department of Particle Physics and Astrophysics
    Contact
    DetailsShow full text description of 14:45 - Light Refreshments...»
    14:45 - Light Refreshments
    AbstractShow full text abstract about Time-urgent policy decisions are increasingly benefiting fro...»
    Time-urgent policy decisions are increasingly benefiting from the scientific assessments of risks and outcomes. However the ability to inject science into decision processes can be haphazard, requiring awareness of potential tools and involvement in the policy decisions. I hope to provide some insight on how science is drawn into decisions through a series of examples including the Fukushima Daiichi accident and aircraft safety to the Gulf oil spill and Ebola.
    Lecture
  • Date:03TuesdayMarch 2015

    The Interface of Science and Policy

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    Time
    15:00 - 16:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Drory Auditorium
    Lecturer
    Dimitri Kusnezov
    Chief Scientist, US Department of Energy, National Nuclear Security Administration
    Organizer
    Department of Particle Physics and Astrophysics
    Contact
    DetailsShow full text description of 14:45 - Light Refreshments...»
    14:45 - Light Refreshments
    AbstractShow full text abstract about Time-urgent policy decisions are increasingly benefiting fro...»
    Time-urgent policy decisions are increasingly benefiting from the scientific assessments of risks and outcomes. However the ability to inject science into decision processes can be haphazard, requiring awareness of potential tools and involvement in the policy decisions. I hope to provide some insight on how science is drawn into decisions through a series of examples including the Fukushima Daiichi accident and aircraft safety to the Gulf oil spill and Ebola.
    Lecture
  • Date:04WednesdayMarch 2015

    Forum on Mathematical Principles in Biology

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    Time
    10:00 - 11:00
    Title
    The stem cell challenge: making the right cells at the right time
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Shalev Itzkovitz
    Dept of Molecular Cell Biology
    Organizer
    Department of Molecular Cell Biology
    System Biology
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    Lecture
  • Date:04WednesdayMarch 2015

    G-INCPM-Special Seminar - lecture will be in Hebrew - Dr. Ori Inbar, Researcher at Evogene & Chairperson of the Israeli CF Foundation - Kalydeco - breakthrough personalized medicine for Cystic Fibrosis (CF)

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    Time
    11:00 - 12:30
    Location
    Michael and Anna Wix Auditorium
    Small Wix
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Cystic Fibrosis (CF) is the most frequent life threatening g...»
    Cystic Fibrosis (CF) is the most frequent life threatening genetic disorder in the western world. The disease is caused by mutations in the CFTR genes that encode a chloride membrane channel protein that is expressed in epithelial cells. Malfunction of this protein causes a multi system disorder: lungs, pancreas, intestine, liver, bones, sweat glands and male reproductive system. Two years ago the FDA approved Kalydeco, the first personalized drug which is mutation specific: for CF patients that have at least one copy of the mutation G551D. Binding of Kalydeco to the impaired CFTR protein restores its functionality.
    The following will be reviewed: CF-genetic basis, prognosis, treatments and genetic tests in Israel and Kalydeco - mode of action, clinical effect on patients, future development and its Israeli angle.
    Lecture
  • Date:04WednesdayMarch 2015

    POPULAR LECTURES - IN HEBREW

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    Time
    12:00 - 13:00
    Title
    על אצות, פוטונים ונוירונים: שיטות חדשות בחקר המוח
    Location
    Dolfi and Lola Ebner Auditorium
    Lecturer
    Ofer Yizhar
    Contact
    Lecture
  • Date:05ThursdayMarch 2015

    Open Day for M.Sc. Life Science students

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    Time
    08:30 - 12:30
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Chairperson
    Ziv Reich
    Contact
    Conference
  • Date:05ThursdayMarch 2015

    Magnetic Resonance Seminar

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    Time
    09:00
    Title
    How can ultra-high magnetic fields help in preclinical functional MRI studies?
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Dr. Luisa Ciobanu
    Neurospin, CEA-Saclay, France
    Organizer
    Department of Chemical and Biological Physics
    Contact
    AbstractShow full text abstract about In fMRI studies, contrast-to-noise ratio and spatial resolut...»
    In fMRI studies, contrast-to-noise ratio and spatial resolution can be improved by using ultra-high magnetic fields. Traditionally, fMRI experiments are performed using the Blood Oxygen Level Dependent (BOLD) technique based on echo planar imaging (EPI) acquisition strategies. When using EPI, certain unwanted effects such as image blurring, distortions and signal voids enhance as the magnetic field strength increases. In the first part of my talk I will present the use of a different acquisition scheme, spatiotemporal encoding (SPEN), which has the potential to improve image quality, offering an attractive alternative to EPI for UHF fMRI.
    In the second part of my presentation I will focus on two other approaches to imaging brain function: Diffusion fMRI (DfMRI) and Manganese Enhanced MRI (MEMRI). Specifically, I will present studies which highlight the advantages and disadvantages of each of these techniques with respect to BOLD.
    Lecture
  • Date:06FridayMarch 2015

    "Michael"

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    Time
    21:30
    Location
    Michael and Anna Wix Auditorium
    Contact
    DetailsShow full text description of Cult show that appeared throughout Israel for more than 4 Ye...»
    Cult show that appeared throughout Israel for more than 4 Years.
    Ensamble Michael hosting the actress Liat Harlev.
    Cultural Events