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July 01-31, 2017

  • Date:02SundayJuly 201711TuesdayJuly 2017

    SRitp Workshop: Post Strings

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    Time
    08:00 - 08:00
    Location
    Nella and Leon Benoziyo Physics Library
    Chairperson
    Micha Berkooz
    Organizer
    Department of Particle Physics and Astrophysics
    Homepage
    Contact
    Conference
  • Date:02SundayJuly 2017

    To be announced

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    Time
    13:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Tzahi Noiman
    Chaim Kahana's group, Dept. of Molecular Genetics, WIS
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:03MondayJuly 201707FridayJuly 2017

    Galois Meets Newton: Algebraic and Geometric aspects of Singularity Theory Celebrating the 70th birthday of Prof. Askold Khovanskii

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    Time
    08:00 - 08:00
    Location
    David Lopatie Conference Centre
    Chairperson
    Sergei Yakovenko
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    Conference
  • Date:03MondayJuly 2017

    Chemistry colloquium - title tbd

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    Time
    11:00 - 12:15
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Judith P. Klinman
    UC Berkeley
    Organizer
    Faculty of Chemistry
    Contact
    Colloquia
  • Date:03MondayJuly 2017

    Neural Representations of Natural Self Motion: Implications for Perception & Action

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    Time
    12:30
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Kathleen Cullen
    Dept of Biomedical Engineering, Johns Hopkins University
    Organizer
    Department of Brain Sciences
    Contact
    DetailsShow full text description of Host: Nachum Ulanovsky nachum.ulanovsky@weizmann.ac.il tel:6...»
    Host: Nachum Ulanovsky nachum.ulanovsky@weizmann.ac.il tel:6301
    For assistance with accessibility issues,
    please contact naomi.moses@weizmann.ac.il
    AbstractShow full text abstract about The vestibular system detects self-motion and in turn genera...»
    The vestibular system detects self-motion and in turn generates reflexes that are crucial for our daily activities, such as stabilizing the visual axis (gaze) and maintaining head and body posture. In addition, the vestibular system provides us with our subjective sense of movement and orientation in space. The loss vestibular function due to aging, injury, or disease produces dizziness, postural imbalance, and an increased risk of falls – all symptoms that profoundly impair quality of life.

    In this talk, I will describe how the brain processes vestibular information in natural conditions. Notably, our work has established how early stages of processing encode vestibular stimuli and integrate them with extra-vestibular cues – for example proprioceptive and premotor information to ensure accurate perception and behaviour. Our experiments have revealed that while vestibular afferents respond identically to externally-generated and actively-generated self-motion, this is not the case at first central stage of sensory processing. Neurons mediating the vestibulo-spinal reflexes, as well as ascending thalamocortical pathways, are robustly activated during externally-generated motion, however their sensory response are cancelled during actively-generated movements. Our work has further revealed that this cancellation of actively-generated vestibular input occurs only in conditions where the actual sensory signal matches the brain’s internal estimate of the expected sensory consequences of active movement. Moreover, when unexpected vestibular inputs becomes persistent during voluntary motion, a cerebellar-based cancellation mechanism is rapidly updated to re-enable the vital distinction between self-generated and externally-applied stimulation to ensure the maintenance of posture and stable perception. In contrast, vestibular pathways mediating the vestibulo-ocular reflex, employ a different strategy. In this pathway, head velocity is robustly encoded whenever the goal is to stabilize gaze, but when the goal is to voluntarily redirect gaze an efferent copy of the gaze command suppresses the efficacy of this reflex pathway. Taken together, these findings have important implications for understanding the neural basis of perception and action during self-motion.
    Lecture
  • Date:04TuesdayJuly 2017

    Non-deadly function of the effector protein of necroptosis- MLKL.

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    Time
    10:00 - 10:30
    Location
    Wolfson Building for Biological Research
    Auditorium
    Lecturer
    Dr. Seongmin Yoon
    Dept. of Biomolecular Sciences - WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about The proteins believed to serve critical roles in the signali...»
    The proteins believed to serve critical roles in the signaling pathways activated by receptors of the TNF family have been identified almost two decades ago. However, clarification of the exact functional roles of the proteins is still at its infancy. It is obvious that none of these proteins serves only the role initially known for it. Pseudokinase Mixed Lineage Kinase Domain-Like (MLKL) by proinflammatory ligands such as TNF triggers necroptosis, programmed cell death in which rupture of cellular membranes yields release of components that are potentially pro-inflammatory, occurs upon phosphorylation of MLKL by RIPK3. We report that MLKL also controls transport of endocytosed proteins, thereby enhancing degradation of receptors and ligands, modulating their induced signaling, and facilitating generation of extracellular vesicles. This role is exerted on two quantitative levels: a constitutive one independent of RIPK3, and an enhancement triggered by RIPK3. RIPK3 activation induces, prior to any sign of death, association of MLKL with ESCRT proteins and the flotillins, and exclusion of phospho-MLKL from cells within vesicles in association with these proteins. We suggest that release of phosphorylated MLKL within extracellular vesicles serves as a mechanism for self-restricting the necroptotic activity of this protein.

    Lecture
  • Date:04TuesdayJuly 2017

    Clock control by polyamine levels through a mechanism that declines with age

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    Time
    10:30 - 11:00
    Location
    Wolfson Building for Biological Research
    Auditorium
    Lecturer
    Ziv Zwighaft
    Members - Dept. of Biomolecular Sciences-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Abstract Polyamines are essential polycations present in a...»
    Abstract
    Polyamines are essential polycations present in all living cells. Polyamine levels are maintained from the diet and de-novo synthesis, and their decline with age is associated with various pathologies. Here we found that polyamine levels oscillate in a daily manner. Both clock- and feeding-dependent mechanisms regulate the daily accumulation of key enzymes in polyamine biosynthesis through rhythmic binding of BMAL1:CLOCK to conserved DNA elements. In turn, polyamines control the circadian period in cultured cells and animals by regulating the interaction between the core clock repressors PER2 and CRY1. Importantly, we show that the decline in polyamine levels with age in mice is associated with a longer circadian period that can be reversed upon polyamine supplementation in the diet. Our findings suggest a cross talk between circadian clocks and polyamines biosynthesis that participate in circadian control, and open new possibilities for nutritional interventions against the decay in clock’s function with age.


    Highlights
    • Diurnal regulation of polyamine biosynthesis by circadian clock and feeding.
    • Polyamine levels regulate the circadian period in cultured cells and mice.
    • Polyamines modulate the interaction between the core clock proteins PER2 and CRY1.
    • Lengthening of the circadian period with age can be reversed by polyamines.

    Lecture
  • Date:04TuesdayJuly 2017

    AMO Journal Club

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    Time
    13:15
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Auditorium
    Organizer
    Department of Physics of Complex Systems
    Optics and Atomic Physics Seminar
    Contact
    AbstractShow full text abstract about Speakers: Dekel Raanan, Eilon Poem-Kalogerakis ...»
    Speakers: Dekel Raanan, Eilon Poem-Kalogerakis
    Lecture
  • Date:04TuesdayJuly 2017

    Molecular Neuroscience Forum Seminar

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    Time
    14:00 - 15:00
    Title
    Glia control repetitive motion and sleep in C. elegans.
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Menachem Katz
    Rockefeller University
    Organizer
    Department of Biomolecular Sciences
    Homepage
    Contact
    Lecture
  • Date:04TuesdayJuly 2017

    "Applications of SEC-MALS to Protein Characterization"

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    Time
    14:00 - 15:00
    Location
    Helen and Milton A. Kimmelman Building
    Dov Elad Room
    Lecturer
    Dr.. Dan Some
    Wyatt
    Organizer
    Department of Chemical and Structural Biology
    Contact
    AbstractShow full text abstract about Conventional analytical size exclusion chromatography (SEC),...»
    Conventional analytical size exclusion chromatography (SEC), often used to determine the solution molecular weight of proteins, is subject to inherent limitations and errors. Multi-angle light scattering (MALS) is a first-principles technique for determining the molar mass and size of macromolecules and nanoparticles in solution, independently of conformation. In combination with SEC, MALS overcomes these obstacles to characterize the biophysical properties of proteins and other biomolecules, including molecular weight, size, native oligomeric state, dynamic equilibria and degradation products.

    This seminar will present the failure modes of analytical SEC, fundamentals of SEC-MALS and examples of applications to a variety of proteins including IgG, insulin, glycoproteins, membrane proteins and protein complexes as well as viruses and virus-like particles. It will touch on the importance of protein quality control for reproducible science and provide a glimpse into how MALS can analyze complicated protein-protein interactions.
    Lecture
  • Date:04TuesdayJuly 2017

    The lion that loved strawberries- Children's theater

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    Time
    17:30
    Location
    Michael and Anna Wix Auditorium
    Contact
    Cultural Events
  • Date:05WednesdayJuly 2017

    "The Reactive Oxygen Driven Tumor: An Update"

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    Time
    10:00 - 11:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Jack L. Arbiser, M.D., Ph.D
    Thomas J. Lawley Professor of Dermatology Department of Dermatology Emory University School of Medicine Winship Cancer Institute Atlanta Veterans Administration Health Center
    Organizer
    Department of Molecular Cell Biology
    Contact
    Lecture
  • Date:05WednesdayJuly 2017

    The Israel Camerata Jerusalem - Corners of the World

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    Time
    20:00
    Location
    Michael and Anna Wix Auditorium
    Contact
    DetailsShow full text description of Avner Biron conductor Marita Sølberg soprano (Norway) Mark...»
    Avner Biron conductor
    Marita Sølberg soprano (Norway)
    Mark Bebbington piano (UK)

    Grieg / Peer Gynt, suites no. 1 & no. 2
    John Ireland / Piano Concerto in E-flat Major
    Grieg / "The Last Spring" from Two Elegiac Melodies
    Mozart / aria "Per Pieta Bel Idol Mio"
    Mozart / aria "Non Curo L'affetto"
    Mozart / aria "Basta vincesti"
    Avi Eilam-Amzallag / "My Heart is in the East" (world premiere)
    Cultural Events
  • Date:06ThursdayJuly 2017

    Organoid Student Club Seminar ("Generation of lung organoids from fetal and adult lung progenitors")

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    Time
    11:00 - 12:00
    Location
    Wolfson Building for Biological Research
    Seminar Room
    Organizer
    Department of Molecular Cell Biology
    Contact
    Lecture
  • Date:06ThursdayJuly 2017

    Variability and Statistics of Failure of Commercial Li-ion Batteries

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    Time
    11:00 - 12:00
    Location
    Perlman Chemical Sciences Building
    Room 404
    Lecturer
    Dr. Stephen J. Harris
    Lawrence Berkeley National Laboratory
    Organizer
    Department of Molecular Chemistry and Materials Science
    Contact
    DetailsShow full text description of Traditionally, battery electrodes have been considered to be...»
    Traditionally, battery electrodes have been considered to be homogeneous and 1-dimensional—e.g., porosity is assumed constant everywhere, the state of charge at any point within one electrode is assumed to depend only on its distance from the other electrode. However, failure in essentially all real materials is initiated at a heterogeneity (weak spot), which might be at the largest flaw. Thus, a solid with some scratches will generally fracture at the largest one. As a result, a homogeneous electrode model normally cannot, by its very nature, predict cell failure unless it includes adjustable parameters.
    In this talk I will review some evidence for the presence and possible importance of heterogeneities in battery electrodes. I will propose that in some cases the critical electrode flaws are relatively rare and statistically distributed through a collection of nominally identical battery samples. Under these conditions there will be two important consequences that are only rarely addressed or even recognized in the academic battery literature:
    (1) Failure lifetime may have a wide distribution. For example, my cell phone battery lasts only 18 months; yours lasts 2½ years. In that case, characterizing battery life by a single number may not be very useful.
    (2) Degradation may not be uniformly spatially distributed across a pouch cell. This can lead to a misdiagnosis of the problem. For example, if most of the degradation in a pouch cell takes place at the edges, then there may be leaks there. Trying to improve the electrode material would then be attacking the wrong problem.
    I will provide evidence for (1) and (2) and discuss why thinking about these factors might be useful for producing longer-lived commercial batteries.
    Lecture
  • Date:06ThursdayJuly 2017

    Imm Student Seminars by Yadav Sandeep Kumar & Matthias Kramer -Thursday, July 6th, 2017

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    Time
    14:00 - 15:00
    Location
    Wolfson Building for Biological Research
    Auditorium
    Organizer
    Department of Systems Immunology
    Contact
    DetailsShow full text description of 14:00-14:30: Yadav Sandeep Kumar- will lecture on: “The rol...»
    14:00-14:30: Yadav Sandeep Kumar- will lecture on:
    “The role of the leukocyte Nuclear Lamina in migration.”
    14:30-15:00: Matthias Kramer- will lecture on:
    “Deciphering the role of FAT10 in Cancer-Related Inflammation.”
    Lecture
  • Date:06ThursdayJuly 2017

    Imm Student Seminars by Yadav Sandeep Kumar & Matthias Kramer -Thursday, July 6th, 2017

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    Time
    14:00 - 15:00
    Location
    Wolfson Building for Biological Research
    Auditorium
    Organizer
    Department of Systems Immunology
    Contact
    DetailsShow full text description of 14:00-14:30: Yadav Sandeep Kumar- will lecture on: “The rol...»
    14:00-14:30: Yadav Sandeep Kumar- will lecture on:
    “The role of the leukocyte Nuclear Lamina in migration.”
    14:30-15:00: Matthias Kramer- will lecture on:
    “Deciphering the role of FAT10 in Cancer-Related Inflammation.”
    Lecture
  • Date:09SundayJuly 2017

    Global Political and Economic Trends Affecting Energy Trade, Consumption and Production

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    Time
    13:00
    Title
    Sustainability And Energy Research Initiative (SAERI) Seminar Series
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Brenda Shaffer
    Visiting Researcher, Georgetown University and Senior Fellow, Global Energy Center, Atlantic Council, Washington, DC.
    Organizer
    Feinberg Graduate School
    Alternative Sustainable Energy Research Initiative (AERI)
    Contact
    DetailsShow full text description of Gathering & refreshments at 12:40...»
    Gathering & refreshments at 12:40
    Lecture
  • Date:10MondayJuly 2017

    Exploring the Synthesis and Applications of Graphene

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    Time
    11:00 - 12:00
    Location
    Perlman Chemical Sciences Building
    Room 404
    Lecturer
    Prof. Richard B. Kaner
    Department of Chemistry and Biochemistry, UCLA
    Organizer
    Department of Molecular Chemistry and Materials Science
    Contact
    DetailsShow full text description of Graphene is the ultimate two-dimensional material consisti...»

    Graphene is the ultimate two-dimensional material consisting of a single layer of sp2 hybridized carbon. Here we explore different approaches to synthesize this carbon allotrope, ranging from chemical conversion to vapor phase deposition. Briefly, graphite can be converted into graphene oxide (GO) sheets, which readily disperse in water, and then can be reduced by various methods.1-2 Due to its unique ability to be solution processed and patterned, GO and chemically converted graphene hold promise for applications ranging from sensors to transparent conducting electrodes.3-4 Chemical vapor deposition onto metal substrates enables the growth of continuous, large-area graphene (Fig. 1). The challenges of growing graphene, controlling the number of layers, transferring graphene and some exciting uses such as laser scribed graphene for supercapacitors will be discussed.5-6

    Fig. Large-area single layer graphene transferred onto a silicon substrate with a 300 nm oxide can be seen with the naked eye, while STM imaging enables seeing the honeycomb network of carbon that makes this material so robust.
    Lecture
  • Date:10MondayJuly 2017

    Special Chemical Physics Seminar

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    Time
    14:00
    Title
    The Dirac electron: spin, size, mass, charge, and universal constants‎
    Location
    Perlman Chemical Sciences Building
    Room 404
    Lecturer
    Prof. Jean Maruani
    CNRS & UPMC‎
    Organizer
    Department of Chemical and Biological Physics
    Contact
    Lecture

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