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  • Date:12TuesdayDecember 2017

    "Bistability and Multi-stability in Dynamic Protein Networks"

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    Time
    14:00
    Location
    Helen and Milton A. Kimmelman Building
    Dov Elad Room
    Lecturer
    Prof. Gonen Ashkenasy
    BGU
    Organizer
    Department of Structural Biology
    Contact
    Lecture
  • Date:12TuesdayDecember 2017

    Seminar in Geometry and Topology

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    Time
    16:15 - 17:30
    Title
    Tempered Manifolds and Schwartz Functions on Them
    Location
    Jacob Ziskind Building
    Room 290C
    Lecturer
    Ary Shaviv
    WIS
    Organizer
    Faculty of Mathematics and Computer Science, Department of Computer Science and Applied Mathematics, Department of Mathematics
    Contact
    AbstractShow full text abstract about Schwartz functions are classically defined as smooth functio...»
    Schwartz functions are classically defined as smooth functions such that they, and all their (partial) derivatives, decay at infinity faster than the inverse of any polynomial. This was formulated on $mathbb{R}^n$ by Laurent Schwartz, and later on Nash manifolds (smooth semi-algebraic varieties) by Fokko du Cloux and by Rami Aizenbud and Dima Gourevitch. In a joint work with Boaz Elazar we have extended the theory of Schwartz functions to the category of (possibly singular) real algebraic varieties. The basic idea is to define Schwartz functions on a (closed) algebraic subset of $mathbb{R}^n$ as restrictions of Schwartz functions on $mathbb{R}^n$.
    Both in the Nash and the algebraic categories there exists a very useful characterization of Schwartz functions on open subsets, in terms of Schwartz functions on the embedding space: loosely speaking, Schwartz functions on an open subset are exactly restrictions of Schwartz functions on the embedding space, which are zero "to infinite order" on the complement to this open subset. This characterization suggests a very intuitive way to attach a space of Schwartz functions to an arbitrary (not necessarily semi-algebraic) open subset of $mathbb{R}^n$.
    In this talk, I will explain this construction, and more generally the construction of the category of tempered smooth manifolds. This category is in a sense the "largest" category whose objects "look" locally like open subsets of $mathbb{R}^n$ (for some $n$), and on which Schwartz functions may be defined. In the development of this theory some classical results of Whitney are used, mainly Whitney type partition of unity (this will also be explained in the talk). As time permits, I will show some properties of Schwartz functions, and describe some possible applications. This is a work in progress.
    Lecture
  • Date:13WednesdayDecember 201714ThursdayDecember 2017

    Studying Complex Behaviour- A Dr. Daniel Andreae Symposium

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    Time
    08:00 - 08:00
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Chairperson
    Alon Chen
    Homepage
    Contact
    Conference
  • Date:14ThursdayDecember 2017

    Physics Colloquium

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    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Auditorium
    Lecturer
    Prof. Diedrik Wiersma
    University of Florence, Italy
    Organizer
    Faculty of Physics
    Contact
    DetailsShow full text description of 11:00 Coffee, Tea and more ...»
    11:00 Coffee, Tea and more
    AbstractShow full text abstract about TBA ...»
    TBA
    Colloquia
  • Date:18MondayDecember 2017

    Unexpected Adventures with Human Endogenous Retroviruses and Centromeres

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    Time
    14:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Prof. David Markovitz
    Organizer
    Department of Molecular Genetics
    Contact
    Lecture
  • Date:18MondayDecember 2017

    Life Sciences Faculties' Council

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    Time
    15:00 - 18:00
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Contact
    Academic Events
  • Date:19TuesdayDecember 201721ThursdayDecember 2017

    Israel-Turkey meeting on nanoscale science

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    Time
    08:00 - 08:00
    Location
    David Lopatie Conference Centre
    Kimmel Auditorium
    Chairperson
    Reshef Tenne
    Homepage
    Contact
    Conference
  • Date:19TuesdayDecember 2017

    To be announced

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    Time
    10:00 - 10:30
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Vered Shacham
    Members - Dept. of Biomolecular Sciences-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    Lecture
  • Date:19TuesdayDecember 2017

    Frontiers in Systems Biology: Prof. Mihaela Zavolan

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    Time
    10:00 - 11:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Prof. Mihaela Zavolan
    Biozentrum, University of Basel, Switzerland
    Organizer
    The Azrieli Institute for Systems Biology
    Contact
    Lecture
  • Date:19TuesdayDecember 2017

    T-cell immune suppression by the cytoplasmic tail of the HIV gp41 fusion protein

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    Time
    10:30 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Yoel A. Klug
    Members - Dept. of Biomolecular Sciences-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about HIV enters its host cells by membrane fusion, initiated by t...»
    HIV enters its host cells by membrane fusion, initiated by the gp41 subunit of its envelope protein. In addition, gp41 has been shown to prevent T-cell activation. This is suggested to occur during the membrane fusion process and is attributed to various membrane binding regions of gp41. Although extensively studied, the cytosolic region of gp41, termed the cytoplasmic tail (CT), has not been examined in the context of immune suppression. Here we investigated whether the CT inhibits T-cell activation by utilizing gp41 derived peptides and full gp41 constructs expressed in human T-cells. We found that a conserved region of the CT specifically inhibits T-cell activation through a unique inhibitory mechanism able to take place post membrane fusion.
    Lecture
  • Date:19TuesdayDecember 2017

    "How changes to the cellular environment modulate protein structure, function, and interaction"

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    Time
    14:00 - 15:00
    Location
    Helen and Milton A. Kimmelman Building
    Dov Elad Room
    Lecturer
    Dr. Shahar Sukenik
    University of Illinois
    Organizer
    Department of Structural Biology
    Contact
    Lecture
  • Date:21ThursdayDecember 2017

    Physics Colloquium

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    Time
    11:15 - 12:30
    Location
    Edna and K.B. Weissman Building of Physical Sciences
    Auditorium
    Lecturer
    TBA
    Organizer
    Faculty of Physics
    Contact
    DetailsShow full text description of 11:00 Coffee, Tea and more ...»
    11:00 Coffee, Tea and more
    AbstractShow full text abstract about TBA ...»
    TBA
    Colloquia
  • Date:21ThursdayDecember 2017

    "Gender in practice: the user’s guide"

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    Time
    11:30 - 13:00
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Dr. Zeev Lehrer
    Contact
    DetailsShow full text description of Social psychologist and sociologist , lecturer at the Gender...»
    Social psychologist and sociologist , lecturer at the Gender Studies program at Tel Aviv university and the Peres Academic Center.
    A well known expert and consultant in the field of gender in organization.
    AbstractShow full text abstract about Dr. Zeev Lehrer presents a different, practical point of vie...»
    Dr. Zeev Lehrer presents a different, practical point of view on the confluence between gender and organizations. Suspending questions of justice, responsibility and blame, Lehrer supplies simple and practical tools to manage and solve real gender problems in real life situations.
    Lecture
  • Date:24SundayDecember 2017

    Looking for the right approach of renewable energy utilization

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    Time
    13:00
    Title
    SAERI: Sustainability And Energy Research Initiative
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Jacob Karni,
    Department of Earth and Planetary Sciences, The Weizmann Institute of Science
    Organizer
    Feinberg Graduate School
    Contact
    DetailsShow full text description of Light refreshments will be served at 12:40...»
    Light refreshments will be served at 12:40
    Lecture
  • Date:25MondayDecember 2017

    The QTY Code: A simple tool for membrane protein engineering

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    Time
    09:00 - 10:00
    Title
    (Can you convert a hydrophobic alpha helix into a hydrophilic one?)
    Location
    Camelia Botnar Building
    Botnar Auditorium
    Lecturer
    Prof. Shuguang Zhang
    Center for Biomedical Engineering, MIT
    Organizer
    Department of Structural Biology
    Contact
    DetailsShow full text description of Special Joint Seminar of Dept Structural Biology and Structu...»
    Special Joint Seminar of Dept Structural Biology and Structural Proteomics Unit
    Lecture
  • Date:25MondayDecember 2017

    The QTY Code: A simple tool for membrane protein engineering. Subtitle: (Can you convert a hydrophobic alpha helix into a hydrophilic one?)

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    Time
    10:00 - 11:00
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Prof. Shuguang Zhang
    Center for Biomedical Engineering, MIT
    Organizer
    Department of Biomolecular Sciences
    Contact
    DetailsShow full text description of Hosts: Rina Rosenzweig <rina.rosenzweig@weizmann.ac.il&g...»
    Hosts:
    Rina Rosenzweig <rina.rosenzweig@weizmann.ac.il>
    Dept. Structural Biology
    &
    Joel L. Sussman <joel.sussman@weizmann.ac.il> Structural Proteomics Unit
    Lecture
  • Date:25MondayDecember 2017

    Chemistry Colloquium

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    Time
    11:00 - 12:15
    Location
    Gerhard M.J. Schmidt Lecture Hall
    Lecturer
    Prof. Dmitrii Perepichka
    McGill University
    Organizer
    Faculty of Chemistry
    Contact
    Colloquia
  • Date:25MondayDecember 2017

    Cell-free circulating tumour DNA as a non-invasive tool for cancer diagnostics and research

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    Time
    14:00 - 15:00
    Title
    Cancer Research Club
    Location
    Max and Lillian Candiotty Building
    Auditorium
    Lecturer
    Prof. Nitzan Rosenfeld
    Cancer Research UK, Cambridge Institute University of Cambridge, UK
    Organizer
    Department of Biological Regulation
    Contact
    AbstractShow full text abstract about Cancer is driven by genomic alterations, and can evolve in r...»
    Cancer is driven by genomic alterations, and can evolve in response to selective pressures. Sampling of tumour material however is a limiting factor for both diagnostics and research. Blood plasma contains cell-free fragments of circulating tumour DNA (ctDNA) that can be collected non-invasively. With advanced genomic techniques this becomes an effective source of information. “Liquid biopsy” assays are now entering clinical use for non-invasive molecular profiling of advanced cancers to guide targeted therapy. Serially-collection plasma samples can be used to track response to treatment, cancer progression and emergence of known or new resistance mechanisms. Methods that can detect minute amounts of ctDNA are being used to study early-stage cancer and for detection of minimal residual disease after initial definitive treatment.
    Lecture
  • Date:26TuesdayDecember 2017

    Frontiers in Systems Biology: Dr. Ron Dror

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    Time
    10:00 - 11:00
    Location
    Arthur and Rochelle Belfer Building for Biomedical Research
    Botnar Auditorium
    Lecturer
    Dr. Ron Dror
    Organizer
    The Azrieli Institute for Systems Biology
    Contact
    Lecture
  • Date:26TuesdayDecember 2017

    To be announced

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    Time
    10:00 - 10:30
    Location
    Nella and Leon Benoziyo Building for Biological Sciences
    Auditorium
    Lecturer
    Vered Shacham
    Members - Dept. of Biomolecular Sciences-WIS
    Organizer
    Department of Biomolecular Sciences
    Contact
    Lecture

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