Event Information
Title:
The Nuclear Envelope: A Nexus for Gene Regulation
Type:
Lecture
Sponsor:
Department of Physics of Complex Systems
Lecturer:
Jason D. Lieb
Department of Biology and Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill
Date:
Thursday, May 30, 2013
Time:
10:00
Location:
Arthur and Rochelle Belfer Building for Biomedical Research, Botnar Auditorium
Contact:
Nuclear pores associate with active protein-coding genes in yeast and have been implicated in transcriptional regulation. Here, we show that in addition to transcriptional regulation, key components of C. elegans nuclear pores are required for processing of small non-coding RNAs transcribed by RNA Polymerase III (Pol III). Chromatin immunoprecipitation of NPP-13 and NPP-3, two integral components of the nuclear pore, and importin-