March 29, 1994 - March 29, 2027

  • Date:03TuesdayOctober 2017

    G-INCPM Special Seminar - Prof. Yuval Ebenstein, Dept. of Chemical Physics, School of Chemistry, Tel-Aviv Univ. - "Beyond NGS - Single-Molecule Genomics"

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    Time
    11:00 - 12:30
    Location
    Nancy and Stephen Grand Israel National Center for Personalized Medicine
    Auditorium
    Lecturer
    Prof. Yuval Ebenstein
    Dept. of Chemical Physics School of Chemistry Tel-Aviv Univ.
    Organizer
    Department of Biomolecular Sciences
    Contact
    AbstractShow full text abstract about Next generation sequencing (NGS) is revolutionizing all fiel...»
    Next generation sequencing (NGS) is revolutionizing all fields of biological research but it fails to extract the full range of information associated with genetic material. Complementary genomic technologies that analyze individual, unamplified genomic DNA are filling the gaps in the capabilities of NGS. Using such technologies we gain access to the structural variation and long range patterns of genetic and epigenetic information. Recent results from our lab demonstrate our ability to detect and map the epigenetic marks 5-methylacytosine and 5-hydroxymethylcytosine as well as various forms of DNA damage on individual genomic DNA molecules. This new technology allows genetic and epigenetic variation calling on the single cell level without the need to process single cells.
    Lecture