Publications 1995-2008
     
  1. Trachtenberg, J., Weersink, R. A., Davidson, S. R. H., Haider, M. A., Bogaards, A., Gertner, M. R., Evans, A., Scherz, A., Savard, J., Chin, J. L., Wilson, B. C. and Elhilali, M., (2008), "Vascular-targeted photodynamic therapy (padoporfin, WST09) for recurrent prostate cancer after failure of external beam radiotherapy: a study of escalating light doses", BJU International, 102(5): 556-562.
  2. Preise, D., Oren, R., Glinert, I., Kalchenko, V., Jung, S., Scherz, A. and Salomon, Y., (2008), "Systemic antitumor protection by vascular-targeted photodynamic therapy involves cellular and humoral immunity", Cancer Immunology and Immunotherapy, In Press.
  3. Matin, S., Tinkey, P., Borne, A., Stephens, C., Scherz, A. and Swanson, D., (2008), "A pilot trial of vascular-targeted photodynamic therapy in renal tissue", Journal of Endourology, 21: A94-A95.
  4. Glinert, I. S., Geva, E., Tempel-Brami, C., Brandis, A., Scherz, A. and Salomon, Y., (2008), "Photodynamic ablation of a selected rat embryo: a model for the treatment of extrauterine pregnancy", Human Reproduction, 23(7): 1491-1498.
  5. Felshker, S., Preise, D., Kalchenko, V., Scherz, A. and Salomon, Y., (2008), "Prompt Assessment Of Wst11-Vtp Outcome Using Luciferase Transfected Tumors Enables Second Treatment And Increase In Overall Therapeutic Rate", Photochemistry and Photobiology, In press.
  6. Berdugo, M., Bejjani, R. A., Valamanesh, F., Savoldelli, M., Jeanny, J. C., Blanc, D., Ficheux, H., Scherz, A., Salomon, Y., BenEzra, D. and Behar-Cohen, F., (2008), "Evaluation of the new photosensitizer stakel (WST-11) for photodynamic choroidal vessel occlusion in rabbit and rat eyes", Investigative Ophthalmology & Visual Science, 49(4): 1633-1644.
  7. Trachtenberg, J., Bogaards, A., Weersink, R. A., Haider, M. A., Evans, A., McCluskey, S. A., Scherz, A., Gertner, M. R., Yue, C., Appu, S., Aprikian, A., Savard, J., Wilson, B. C. and Elhilali, M., (2007), "Vascular targeted photodynamic therapy with palladium-bacteriopheophorbide photosensitizer for recurrent prostate cancer following definitive radiation therapy: Assessment of safety and treatment response", Journal of Urology, 178(5): 1974-1979.
  8. Tempel-Brami, C., Pinkas, I., Scherz, A. and Salomon, Y., (2007), "Detection Of Light Images By Simple Tissues As Visualized By Photosensitized Magnetic Resonance Imaging", PLoS ONE, 2(11): e1191.
  9. Meerovich, I. G., Brandis, A., Meerovich, G. A., Stratonnikov, A. A., Bendel, P., Oborotova, N. A., Scherz, A. and Baryshnikov, Y., A., (2007), "Study of manganese bacteriopheophorbide as a potential contrast agent for magnetic resonance tomography", Bulletin of Experimental Biology and Medicine, 143(4): 452-454.
  10. Yerushalmi, R., Brandis, A., Rosenbach-Belkin, V., Baldridge, K. K. and Scherz, A., (2006), "Modulation of fragmental charge transfer via hydrogen bonds. Direct measurement of electronic contributions", Journal of Physical Chemistry A, 110(2): 412-421.
  11. Yerushalmi, R., Ashur, I. and Scherz, A., (2006), "Metal-substituted bacteriochlorophylls: novel molecular tools", In: Grimm B., Porra R. J., Rudiger W. and Scheer H. (eds), Chlorophylls and Bacteriochlorophylls: Biochemistry, Biophysics, Functions and Applications. Advances in Photosynthesis and Respiration, vol 25. Springer, Dordrecht: 495-503.
  12. Shlyk-Kerner, O., Samish, I., Kaftan, D., Holland, N., Sai, P. S. M., Kless, H. and Scherz, A., (2006), "Protein flexibility acclimatizes photosynthetic energy conversion to the ambient temperature", Nature, 442(7104): 827-830.
  13. Filip-Granit, N., van der Boom, M. E., Yerushalmi, R., Scherz, A. and Cohen, H., (2006), "Submolecular potential profiling across organic monolayers", Nano Letters, 6(12): 2848-2851.
  14. Brandis, A. S., Salomon, Y. and Scherz, A., (2006), "Chlorophyll sensitizers in photodynamic therapy", In: Grimm B., Porra R. J., Rudiger W. and Scheer H. (eds), Chlorophylls and Bacteriochlorophylls: Biochemistry, Biophysics, Functions and Applications. Advances in Photosynthesis and Respiration, vol 25. Springer, Dordrecht: 461-483.
  15. Brandis, A. S., Salomon, Y. and Scherz, A., (2006), "Bacteriochlorophyll sensitizers in photodynamic therapy", In: Grimm B., Porra R. J., Rudiger W. and Scheer H. (eds), Chlorophylls and Bacteriochlorophylls: Biochemistry, Biophysics, Functions and Applications. Advances in Photosynthesis and Respiration, vol 25. Springer, Dordrecht: 485-494.
  16. Yerushalmi, R., Scherz, A., van der Boom, M. E. and Kraatz, H. B., (2005), "Stimuli responsive materials: new avenues toward smart organic devices", Journal of Materials Chemistry, 15(42): 4480-4487.
  17. Vilensky, J., Koudinova, N. V., Harmelin, A., Scherz, A. and Salomon, Y., (2005), "Vascular-targeted photodynamic therapy (VTP) of a canine-transmissible venereal tumour in a murine model with Pd-bacteriopheophorbide (WST09)", Veterinary and Comparative Oncology, 3(4): 182-193.
  18. Vakrat-Haglili, Y., Weiner, L., Brumfeld, V., Brandis, A., Salomon, Y., McIlroy, B., Wilson, B. C., Pawlak, A., Rozanowska, M., Sarna, T. and Scherz, A., (2005), "The microenvironment effect on the generation of reactive oxygen species by Pd-bacteriopheophorbide", Journal of the American Chemical Society, 127(17): 6487-6497.
  19. Posen, Y., Kalchenko, V., Seger, R., Brandis, A., Scherz, A. and Salomon, Y., (2005), "Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species", Journal of Cell Science, 118(9): 1957-1969.
  20. Meerovich, I. G., Kubasova, I. Y., Oborotova, N. A., Demura, S. A., Brandis, A., Rosenbach-Bekin, V., Baryshnikov, A. Y. and Scherz, A., (2005), "Fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine", Proceedings of SPIE, 5973: 59730G1-G11.
  21. Mazor, O., Brandis, A., Plaks, V., Neumark, E., Rosenbach-Belkin, V., Salomon, Y. and Scherz, A., (2005), "WST11, a novel water-soluble bacteriochlorophyll derivative; Cellular uptake, pharmacokinetics, biodistribution and vascular-targeted photodynamic activity using melanoma tumors as a model", Photochemistry and Photobiology, 81(2): 342-351.
  22. Filip-Granit, N., Yerushalmi, R., Brandis, A., van der Boom, M. E. and Scherz, A., (2005), "Uniform approach to Bacteriochlorophyll-based monolayers on conducting, semiconducting, and insulating substrates", Journal of Physical Chemistry B, 109(15): 6933-6935.
  23. Brandis, A., Mazor, O., Neumark, E., Rosenbach-Belkin, V., Salomon, Y. and Scherz, A., (2005), "Novel water-soluble bacteriochlorophyll derivatives for vascular-targeted photodynamic therapy: Synthesis, solubility, phototoxicity and the effect of serum proteins", Photochemistry and Photobiology, 81(4): 983-993.
  24. Yerushalmi, R., Scherz, A. and van der Boom, M. E., (2004), "Enhancement of molecular properties in thin films by controlled orientation of molecular building blocks", Journal of the American Chemical Society, 126(9): 2700-2701.
  25. Yerushalmi, R., Scherz, A. and Baldridge, K. K., (2004), "Direct experimental evaluation of charge scheme performance by a molecular charge-meter", Journal of the American Chemical Society, 126(18): 5897-5905.
  26. Plaks, V., Posen, Y., Mazor, O., Brandis, A., Scherz, A. and Salomon, Y., (2004), "Homologous adaptation to oxidative stress induced by the photosensitized Pd-bacteriochlorophyll derivative (WST11) in cultured endothelial cells", Journal of Biological Chemistry, 279(44): 45713-45720.
  27. Plaks, V., Koudinova, N., Nevo, U., Pinthus, J. H., Kanety, H., Eshhar, Z., Ramon, J., Scherz, A., Neeman, M. and Salomon, Y., (2004), "Photodynamic therapy of established prostatic adenocarcinoma with TOOKAD: A biphasic apparent diffusion coefficient change as potential early MRI response marker", Neoplasia, 6(3): 224-233.
  28. Kelleher, D. K., Thews, O., Scherz, A., Salomon, Y. and Vaupel, P., (2004), "Perfusion, oxygenation status and growth of experimental tumors upon photodynamic therapy with Pd-bacteriopheophorbide", International Journal of Oncology, 24(6): 1505-1511.
  29. Yerushalmi, R., Baldridge, K. K. and Scherz, A., (2003), "An experimental look into subelectron charge flow", Journal of the American Chemical Society, 125(42): 12706-12707.
  30. Preise, D., Mazor, O., Koudinova, N., Liscovitch, M., Scherz, A. and Salomon, Y., (2003), "Bypass of tumor drug resistance by antivascular therapy", Neoplasia, 5(6): 475-480.
 

31.

 Koudinova, N. V., Pinthus, J. H., Brandis, A., Brenner, O., Bendel, P., Ramon, J., Eshhar, Z., Scherz, A. and Salomon, Y., (2003), "Photodynamic therapy with Pd-bacteriopheophorbide (TOOKAD): Successful in vivo treatment of human prostatic small cell carcinoma xenografts", International Journal of Cancer, 104(6): 782-789.
  32. Kelleher, D. K., Thews, O., Scherz, A., Salomon, Y. and Vaupel, P., (2003), "Combined hyperthermia and chlorophyll-based photodynamic therapy: tumour growth and metabolic microenvironment", British Journal of Cancer, 89(12): 2333-2339.
  33. Huang, Z., Chen, Q., Brun, P. H., Wilson, B. C., Scherz, A., Salomon, Y., Luck, D., Beckers, J. and Hetzel, F. W., (2003), "Studies of a novel photosensitizer Pd-bacteriopheophorbide (Tookad) for the prostate cancer PDT in canine model", Proceedings of SPIE, 5254: 83-90.
  34. Huang, Z., Chen, Q., Brun, P. H., Wilson, B. C., Scherz, A., Salomon, Y., Luck, D., Beckers, J. and Hetzel, F. W., (2003), "Studies of a novel photosensitizer palladium-bacteriopheophorbide(Tookad) for the treatment of prostate cancer." Proceedings of SPIE, 4952: 104-114.
  35. Gross, S., Gilead, A., Scherz, A., Neeman, M. and Salomon, Y., (2003), "Monitoring photodynamic therapy of solid tumors online by BOLD-contrast MRI", Nature Medicine, 9(10): 1327-1331.
  36. Ashur, I., Brandis, A., Greenwald, M., Vakrat-Haglili, Y., Rosenbach-Belkin, V., Scheer, H. and Scherz, A., (2003), "Control of redox transitions and oxygen species binding in Mn centers by biologically significant ligands; Model studies with [Mn]-bacteriochlorophyll a", Journal of the American Chemical Society, 125(29): 8852-8861.
  37. Yerushalmi, R., Noy, D., Baldridge, K. K. and Scherz, A., (2002), "Mutual control of axial and equatorial ligands: Model studies with [Ni]-bacteriochlorophyll-a", Journal of the American Chemical Society, 124(28): 8406-8415.
  38. Schreiber, S., Gross, S., Brandis, A., Harmelin, A., Rosenbach-Belkin, V., Scherz, A. and Salomon, Y., (2002), "Local photodynamic therapy (PDT) of rat C6 glioma xenografts with Pd-bacteriopheophorbide leads to decreased metastases and increase of animal cure compared with surgery", International Journal of Cancer, 99(2): 279-285.
  39. Mazor, O., de Boisferon, M. H., Lombet, A., Gruaz-Guyon, A., Gayer, B., Skrzydelsky, D., Kohen, F., Forgez, P., Scherz, A., Rostene, W. and Salomon, Y., (2002), "Europium-labeled epidermal growth factor and neurotensin: Novel probes for receptor-binding studies", Analytical Biochemistry, 301(1): 75-81.
  40. Kaftan, D., Brumfeld, V., Nevo, R., Scherz, A. and Reich, Z., (2002), "From chloroplasts to photosystems: in situ scanning force microscopy on intact thylakoid membranes", Embo Journal, 21(22): 6146-6153.
  41. Fiedor, J., Fiedor, L., Kammhuber, N., Scherz, A. and Scheer, H., (2002), "Photodynamics of the bacterlochlorophyll-carotenoid system. 2. Influence of central metal, solvent and beta-carotene on photobleaching of bacteriochlorophyll derivatives", Photochemistry and Photobiology, 76(2): 145-152.
  42. Chen, Q., Huang, Z., Luck, D., Beckers, J., Brun, P. H., Wilson, B. C., Scherz, A., Salomon, Y. and Hetzel, F. W., (2002), "WST09 (TOOKAD) Mediated photodynamic therapy as an alternative modality in treatment of prostate cancer", Proceedings of SPIE, 4612: 29-39.
  43. Chen, Q., Huang, Z., Luck, D., Beckers, J., Brun, P. H., Wilson, B. C., Scherz, A., Salomon, Y. and Hetzel, F. W., (2002), "Preclinical studies in normal canine prostate of a novel palladium-bacteriopheophorbide (WST09) photosensitizer for photodynamic therapy of prostate cancer", Photochemistry and Photobiology, 76(4): 438-445.
 

44.

 Zilberstein, J., Schreiber, S., Bloemers, M. C. W. M., Bendel, P., Neeman, M., Schechtman, E., Kohen, F., Scherz, A. and Salomon, Y., (2001), "Antivascular treatment of solid melanoma tumors with bacteriochlorophyll-serine-based photodynamic therapy", Photochemistry and Photobiology, 73(3): 257-266.
  45. Fiedor, L., Leupold, D., Teuchner, K., Voigt, B., Hunter, C. N., Scherz, A. and Scheer, H., (2001), "Excitation trap approach to analyze size and pigment-pigment coupling: Reconstitution of LH1 antenna of Rhodobacter sphaeroides with Ni-substituted bacteriochlorophyll", Biochemistry, 40(12): 3737-3747.
  46. Fiedor, J., Fiedor, L., Winkler, J., Scherz, A. and Scheer, H., (2001), "Photodynamics of the bacteriochlorophyll-carotenoid system. 1. Bacteriochlorophyll-photosensitized oxygenation of beta-carotene in acetone", Photochemistry and Photobiology, 74(1): 64-71.
  47. Noy, D., Yerushalmi, R., Brumfeld, V., Ashur, I., Scheer, H., Baldridge, K. K. and Scherz, A., (2000), "Optical absorption and computational studies of [Ni]-bacteriochlorophyll-a. New insight into charge distribution between metal and ligands", Journal of the American Chemical Society, 122(16): 3937-3944.
  48. Kolbasov, D. and Scherz, A., (2000), "Asymmetric electron transfer in reaction centers of purple bacteria strongly depends on different electron matrix elements in the active-and inactive branches", Journal of Physical Chemistry B, 104(8): 1802-1809.
  49. Federman, S., Malkin, S. and Scherz, A., (2000), "Excitation energy transfer in aggregates of Photosystem I and Photosystem II of the cyanobacterium Synechocystis sp PCC 6803: Can assembly of the pigment-protein complexes control the extent of spillover?" Photosynthesis Research, 64(2-3): 199-207.
  50. Eichwurzel, I., Stiel, H., Teuchner, K., Leupold, D., Scheer, H., Salomon, Y. and Scherz, A., (2000), "Photophysical consequences of coupling bacteriochlorophyll a with serine and its resulting solubility in water", Photochemistry and Photobiology, 72(2): 204-209.
  51. Amir-Zaltsman, Y., Mazor, O., Gayer, B., Scherz, A., Salomon, Y. and Kohen, F., (2000), "Inhibitors of protein tyrosine phosphorylation: preliminary assessment of activity by time-resolved fluorescence", Luminescence, 15(6): 377-380.
  52. Kelleher, D. K., Thews, O., Rzeznik, J., Scherz, A., Salomon, Y. and Vaupel, P., (1999), "Water-filtered infrared-A radiation: a novel technique for localized hyperthermia in combination with bacteriochlorophyll-based photodynamic therapy", International Journal of Hyperthermia, 15(6): 467-474.
  53. Zilberstein, J., Rosenbach-Belkin, V., Scherz, A. and Salomon, Y., (1998), "A novel tissue inserted optical oxygen microsensor: on-line determination of effective photodynamic therapy in solid melanotic melanoma tumors", In: Photodynamic Tumor Therapy: 2nd and 3rd Generation Photosensitizers (J. G. Moser, Editor), Harwood Academic Publishers: 183-194.
  54. Zilberstein, J., Rosenbach-Belkin, V., Neeman, M., Bendel, P., Kohen, F., Gayer, B., Scherz, A. and Salomon, Y., (1998), "Bacteriochlorophyll based PDT of solid tumors relies on vascular destruction", In: Procedings of the 7th Biennial Congress, The International Photodynamic Association, (Ed. T. Patrice) ISPEN BIOTECH CD-Rom addition.
  55. Scherz, A., Katz, S., Vakrat, Y., Brumfeld, V., Gabelmann, E., Zilberstein, J., Leupold, D., Norris, J. R., Scheer, H. and Salomon, Y., (1998), "Bacteriochlorophyll-serine based photochemotherapy; type III PDT? " In: "Photosynthesis: Mechanisms and Effects" (Ed. G. Garab), Kluwer Acad. Publishers, Dordrecht, the Nederlands, 5: 4207-4212.
  56. Rosenbach-Bekin, V., Chen, L., Fiedor, L., Salomon, Y. and Scherz, A., (1998), "Chlorophyll and bacteriochlorophyllderivatives as photodynamic agents", In: Photodynamic Tumor Therapy: 2nd and 3rd Generation Photosensitizers (J. G. Moser, Editor), Harwood Academic Publishers: 117-125.
  57. Noy, D., Fiedor, L., Hartwich, G., Scheer, H. and Scherz, A., (1998), "Metal-substituted bacteriochlorophylls. 2. Changes in redox potentials and electronic transition energies are dominated by intramolecular electrostatic interactions", Journal of the American Chemical Society, 120(15): 3684-3693.
  58. Moser, J. G., Rosenbach-Belkin, V., Brandis, A., Scherz, A., Scheer, H. and Salomon, Y., (1998), "Bacteriochlorophyllide-Serine: Cellular Uptake Kinetics and Transformation", In: Procedings of the 7th Biennial Congress, The International Photodynamic Association, (Ed. T. Patrice) ISPEN BIOTECH CD-Rom addition.
  59. Katz, S., Vakrat, Y., Brumfeld, V., Weiner, L., Gabelmann, E., Paul, A., Hild, M., Lendt, R., Leopold, D., Norris, J. R., Scheer, H., Moser, J., Salomon, Y. and Scherz, A., (1998), "Bacteriochlorophyll-serine generates only OH radicals under NIR illumination", In: Procedings of the 7th Biennial Congress, The International Photodynamic Association, (Ed. T. Patrice) ISPEN BIOTECH CD-Rom addition.
  60. Kass, H., Lubitz, W., Hartwig, G., Scheer, H., Noy, D. and Scherz, A., (1998), "ENDOR studies of substituted chlorophyll cation radicals", Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy, 54(9): 1141-1156.
  61. Hartwich, G., Fiedor, L., Simonin, I., Cmiel, E., Schafer, W., Noy, D., Scherz, A. and Scheer, H., (1998), "Metal-substituted bacteriochlorophylls. 1. Preparation and influence of metal and coordination on spectra", Journal of the American Chemical Society, 120(15): 3675-3683.
  62. Gall, B., Zehetner, A., Scherz, A. and Scheer, H., (1998), "Modification of pigment composition in the isolated reaction center of photosystem II", Febs Letters, 434(1-2): 88-92.
  63. Chen, L., Gross, S., Rosenbach-Belkin, V., Brandis, A., Scherz, A. and Salomon, Y., (1998), "Photoinactivation of microorganisms by chlorophyll-Serine, bacteriochlorophyll-Serine and by targeted Bacteriohlorophyll-IgG", In: Procedings of the 7th Biennial Congress, The International Photodynamic Association, (Ed. T. Patrice) ISPEN BIOTECH CD-Rom addition.
  64. Zilberstein, J., Bromberg, A., Franz, A., Rosenbach-Belkin, V., Kritzmann, A., Pfefermann, R., Salomon, Y. and Scherz, A., (1997), "Light-dependent oxygen consumption in bacteriochlorophyll-serine-treated melanoma tumors: On-line determination using a tissue-inserted oxygen microsensor", Photochemistry and Photobiology, 65(6): 1012-1019.
  65. Teuchner, K., Stiel, H., Leupold, D., Scherz, A., Noy, D., Simonin, I., Hartwich, G. and Scheer, H., (1997), "Fluorescence and excited state absorption in modified pigments of bacterial photosynthesis - A comparative study of metal-substituted bacteriochlorophylls a", Journal of Luminescence, 72-4: 612-614.
  66. Gross, S., Brandis, A., Chen, L., Rosenbach-Belkin, V., Roehrs, S., Scherz, A. and Salomon, Y., (1997), "Protein-A-mediated targeting of Bacteriochlorophyll-IgG to Staphylococcus aureus: A model for enhanced site-specific photocytotoxicity", Photochemistry and Photobiology, 66(6): 872-878.
  67. Rosenbach-Belkin, V., Chen, L., Fiedor, L., Tregub, I., Pavlotsky, F., Brumfeld, V., Salomon, Y. and Scherz, A., (1996), "Serine conjugates of chlorophyll and bacteriochlorophyll: Photocytotoxicity in vitro and tissue distribution in mice bearing melanoma tumors", Photochemistry and Photobiology, 64(1): 174-181.
  68. Fiedor, L., Rosenbach-Belkin, V., Sai, M. and Scherz, A., (1996), "Preparation of tetrapyrrole-amino acid covalent complexes", Plant Physiology and Biochemistry, 34(3): 393-398.
  69. Oren-Shamir, M., Sai, P. S. M., Edelman, M. and Scherz, A., (1995), "Isolation and Spectroscopic Characterization of a Plantlike Photosystem-II Reaction-Center from the Cyanobacterium Synechocystis Sp-6803", Biochemistry, 34(16): 5523-5526.
  70. Chen, L. X., Wang, Z. Y., Hartwich, G., Katheder, I., Scheer, H., Scherz, A., Montano, P. A. and Norris, J. R., (1995), "An X-Ray-Absorption Study of Chemically-Modified Bacterial Photosynthetic Reaction Centers", Chemical Physics Letters, 234(4-6): 437-444.