Patterning and morphogenesis of many biominerals is a bottom-up process, where chemical-physical processes lead to the prescribed formation of conserved patterns. Macromolecular condenstates have the potenial to modify the chemical factors that control mineralization. For example, dense phases can concentrate dilute species, fractionate phases, and mold shpaes. We employ the concenptual framework of liquid-liquid phase separation to understand the principles of biomineralization.
Selected publications:
Krounbi et al. Chem. Mater. 2021
Peled-Zehavi et al. Adv. Biol. 2021