Publications

2019

  • Schleyer, G., Shahaf, N., Ziv, C., Dong, Y., Meoded, R.A.,  Helfrich, E. J. N.,  Schatz, D., Rosenwasser, S., Rogachev, I., Aharoni, A., Piel, J and Vardi, A. (2019)  In plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids. Nature Microbiology, doi: https://doi.org/10.1038/s41564-018-0336-y

2018

  • Ku, C., Barak-Gavish, N., Maienschein-Cline, M., Green, S. J. and Vardi, A. (2018) Complete Genome Sequence of Sulfitobacter sp. Strain D7, a Virulent Bacterium Isolated from an Emiliania huxleyi Algal Bloom in the North Atlantic. Microbiology Resource Announcement 7:e01379-18. https://doi.org/10.1128/MRA.01379-18.
  • Gibbin, E., Gavish, A., Krueger, T., Kramarsky-Winter, E., Shapiro, O., Guiet, R., Jensen, L., Vardi, A. and Meibom, A. (2018) Vibrio coralliilyticus infection triggers a behavioural response and perturbs nutritional exchange and tissue integrity in a symbiotic coral. The ISME Journal. doi:10.1038/s41396-018-0327-2
  • Gibbin, E., Gavish, A., Domart-Coulon, I., Kramarsky-Winter, E., Shapiro, O., Meibom, A. and Vardi, A. (2018) Using NanoSIMS coupled with microfluidics to visualize the early stages of coral infection by Vibrio coralliilyticus. BMC Microbiology, 18:39. https://doi.org/10.1186/s12866-018-1173-0
  • Barak-Gavish, N., Frada, M.J., Ku, C., Lee, P.A., DiTullio, G.R., Malitsky, S., Aharoni, A., Green, S.J., Rotkopf, R., Kartvelishvily, E., Sheyn, U., Schatz, D. and Vardi A. (2018) Bacterial virulence against an oceanic bloom-forming phytoplankter is mediated by algal DMSP. Science Advances 4(10), eaau5716, doi: 10.1126/sciadv.aau5716
  • Trainic, M., Koren, I., Sharoni, S., Frada, M., Segev, L., Rudich, Y. and Vardi, Assaf, (2018) Infection Dynamics of a Bloom-Forming Alga and Its Virus Determine Airborne Coccolith Emission from Seawater. iScience. doi: http://dx.doi.org/10.2139/ssrn.3188480
  • Shapiro, O. H., Kartvelishvily, E., Kramarsky-Winter, E. and Vardi, A (2018) Magnesium-Rich Nanometric Layer in the Skeleton of Pocillopora damicornis With Possible Involvement in Fibrous Aragonite Deposition. Frontiers in Marine Science. doi: https://doi.org/10.3389/fmars.2018.00246
  • Laber, C. P.,  Hunter, J. E., , Carvalho, F., Collins, J. R., Hunter, E. J., Schieler, B. M., Boss, E., More, K., Frada, M., Thamatrakoln, K., Brown, C. M., Haramaty, L., Ossolinski, J., Fredricks, H., Nissimov, J. I., Vandzura, R., Sheyn, U., Lehahn, Y.,  Chant, R. J., Martins, A. M., Coolen, M. J. L., Vardi, A., DiTullio, G. R., Van Mooy, B. A. S. & Bidle, K. D (2018) Coccolithovirus facilitation of carbon export in the North Atlantic Nature Microbiology  3:537-547. doi:10.1038/s41564-018-0128-4
  • Volpert, A., Graff van Creveld, S., Rosenwasser, S. and Vardi, A. (2018) Diurnal fluctuations in chloroplast GSH redox state regulate susceptibility to oxidative stress and cell fate in a bloom‐forming diatom. Journal of Phycology. doi: 10.1111/jpy.12638
  • Schatz, D. and Vardi, A. (2018) Extracellular Vesicles - new players in cell-cell communication in aquatic environments. Current Opinion in Microbiology. 43:148-154
  • Sheyn, U., Rosenwasser, S., Lehahn, Y., Barak-Gavish, N., Rotkopf, R., Bidle, K.D., Koren, I., Schatz, D. and Vardi, A. (2018) Expression profiling of host and virus during a coccolithophore bloom provides insights into the role of viral infection in promoting carbon export. ISME Journal. doi:10.1038/s41396-017-0004-x

2017

  • Frada MJ, Rosenwasser S, Ben-Dor S, Shemi A, Sabanay H. and Vardi, A. (2017) Morphological switch to a resistant subpopulation in response to viral infection in the bloom-forming coccolithophore Emiliania huxleyi  PLOS Pathogens 13(12): e1006775 doi.org/10.1371/journal.ppat.1006775
  • Schatz, D., Rosenwasser, S., Malitsky, S., Wolf, S.G., Feldmesser, E. and Vardi, A. (2017) Communication via extracellular vesicles enhances viral infection of a cosmopolitan alga. Nature Microbiology. doi:10.1038/s41564-017-0024-3
  • Lehahn, Y., Koren, I., Sharoni, S., d’Ovidio, F., Vardi, A. and Boss, E. (2017) Dispersion/dilution enhances phytoplankton blooms in low-nutrient waters. Nature Communications. doi: 10.1038/ncomms14868
  • Woehle, C., Dagan, T., Landan, G., Vardi, A. and Rosenwasser, S. (2017) Expansion of the redox-sensitive proteome coincides with the plastid endosymbiosis. Nature Plants, doi:10.1038/nplants.2017.66
  • Brodie, J., Ball, S.G., Bouget, F-Y., Chan, C.X., De Clerck, O., Cock, J.M., Gachon, C., Grossman, A.R., Mock, T., Raven, J.A., Saha, M., Smith, A.G., Vardi, A., Yoon, H.S. and Bhattacharya, D. (2017) Biotic interactions as drivers of algal origin and evolution. New Phytologist, doi:10.1111/nph.14760

2016

  • Alcolombri, U., Lei, L., Meltzer, D., Vardi, A. and Tawfik, D.S. (2016) Assigning the algal source of dimethylsulfide using a selective lyase inhibitor. ACS Chemical Biology. doi; 10.1021/acschembio.6b00844
  • Graff van Creveld, S., Rosenwasser, S., Levin, Y. and Vardi, A. (2016) Chronic iron limitation confers transient resistance to oxidative stress in marine diatoms. Plant Physiology, doi:10.1104/pp.16.00840
  • Rosenwasser, S., Ziv, C., Graff van Creveld, S. and Vardi, A. (2016) Virocell Metabolism: Metabolic Innovations During Host–Virus Interactions in the Ocean. Trends Microbiol. 24:821–832. 
  • Shemi, A., Schatz, D., Fredricks, H. F. Van Mooy, B. A. S., Porat, Z. and Vardi, A. (2016) Phosphorus starvation induces membrane remodeling and recycling in Emiliania huxleyi. New Phytologist, 211: 886–898.
  • Ziv, C., Malitsky, S., Othman, A., Ben-Dor, S., Wei, Y., Zheng. S., Aharoni, A., Hornemann, T. and Vardi, A. (2016) Viral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine alga. Proc. Natl. Acad. Sci. USA. doi: 10.1073/pnas.1523168113
  • Shapiro, O.H., Kramarsky-Winter, E., Gavish, A.G., Stocker, R. and Vardi, A. (2016) A coral-on-a-chip microfluidic platform enabling live-imaging microscopy of reef-building corals. Nature Communications 7:10860. doi:10.1038/ncomms10860
  • Malitsky, S., Ziv, C., Rosenwasser, S., Zheng, S., Schatz, D., Porat, Z., Ben-Dor, S., Aharoni, A. and Vardi, A. (2016) Viral infection of the marine alga Emiliania huxleyi triggers lipidome remodeling and induces the production of highly saturated triacylglycerol. New Phytologist. 210:88–96
  • Sheyn, U., Rosenwasser, S., Ben-Dor, S., Porat, Z. and Vardi, A (2016) Modulation of host ROS metabolism is essential for viral infection of a bloom-forming coccolithophore in the ocean. ISME Journal. doi: 10.1038/ismej.2015.228

2015

  • Sharoni, S., Trainic, M., Schatz, D., Lehahn, Y., Flores, M.J., Bidle, K.D., Ben-Dor, S., Rudich, Y., Koren, I. and Vardi, A. (2015)  Infection of phytoplankton by aerosolized marine viruses. Proc. Natl. Acad. Sci. USA. 112:6643–6647.
  • Shemi, A., Ben-Dor, S. and Vardi, A. (2015) Elucidating the composition and conservation of the autophagy pathway in photosynthetic eukaryotes. Autophagy 11:701-15
  • Alcolombri, U., Ben-Dor, S., Feldmesser, E., Levin, Y., Tawfik, D.S. and Vardi, A (2015). Identification of the algal dimethyl sulfide-releasing enzyme: a missing link in the marine sulfur cycle.  Science.348:1466-1469.
  • Graff Van Creveld, S., Rosenwasser, S., Schatz, D., Koren, I and Vardi, A (2015). Early perturbation in mitochondria redox homeostasis in response to environmental stress predicts cell fate in diatoms.  ISME Journal. 9:385-395.
  • Frada, M.J., Vardi, A. (2015). Algal viruses hitchhiking on zooplankton across phytoplankton blooms.  Communicative and Integrative Biology. 8:e1029210

2014

  • Frada, MJ., Schatz, D., Farstey, V., Ossolinski, J.E., Sabanay, H., Ben-Dor, S., Koren, I. and Vardi, A. (2014) Zooplankton may serve as transmission vectors for viruses infecting algal blooms in the ocean. Current Biology. 24:2592–2597.
  • Schatz, D., Shemi, A., Rosenwasser, S., Sabanay, H., Wolf, S.G., Ben-Dor, S. and Vardi, A. (2014) Hijacking of an autophagy-like process is critical for the life cycle of a DNA virus infecting oceanic algal blooms. New Phytologist. 204(4):854-63.
  • Shapiro, O.H., Fernandez, V.I., Garren, M., Guasto, J.S., Debaillon-Vesque, F.P., Kramarsky-Winter, E., Vardi A. and Stocker, R.  (2014) Vortical ciliary flows actively enhance mass transport in reef corals. Proc. Natl. Acad. Sci. USA. 111:13391–13396.
  • Rosenwasser, S., Mausz, M.A., Schatz, D., Sheyn, U., Weinstock, E., Pohnert, G. and Vardi, A. (2014) Rewiring host lipid metabolism by large viruses determines the fate of Emiliania huxleyi, a bloom-forming alga in the ocean. Plant Cell. 26: 2689-2707.
  • Alcolombri, U., Laurino, P., Lara-Astiaso, P., Vardi, A., Tawfik, D.S. (2014) DddD as a CoA-transferase/lyase producing dimethyl sulfide in the marine environment. Biochemistry, 53(34): 5473-5475
  • Lehahn, Y., Koren, I., Rudich, Y., Bidle, K.D., Trainic, M., Flores, M., Sharoni, S., Vardi, A. (2014) Decoupling oceanic and atmospheric factors affecting aerosol loading over a cluster of mesoscale North Atlantic eddies, Geophysical Research Letters 41(11): 4075–4081.
  • Lehahn, Y., Koren, I., Schatz, D., Frada, M., Sheyn, U., Boss, E., Efrati, S., Rudich, Y., Trainic, M., Sharoni, S., Laber, C., DiTullio, G.R., Coolen, M., Martins, A., Van Mooy, B.A.S., Bidle, K.D. and Vardi, A. (2014) Decoupling physical from biological processes to assess the impact of viruses on a mesoscale algal bloom. Current Biology 24(17):2041-2046.
  • Rosenwasser, S., Graff van Creveld, S. Schatz, D., Malitsky, S., Tzfadia, O., Aharoni, A., Levin,Y., Gabashvili, A., Feldmesser, E and Vardi A. (2014) Mapping the diatom redox-sensitive proteome provides insight into response to nitrogen stress in the marine environment. Proc. Natl. Acad. Sci. USA 111(7): 2740–2745.
  • Feldmesser, E., Rosenwasser, S., Vardi, A and Ben-Dor, S. (2014) Improving transcriptome construction in non-model organisms: integrating manual and automated gene definition in Emiliania huxleyi. BMC Genomics 15:148

2012

  • Vardi, A., Haramati, L., Van Mooy, B.A.S.,Fredericks, H.F., Kimmance, S.A., et al. (2012) Host-virus dynamics and subcellular controls of call fate in a natural coccolithophore population.  Proc. Natl. Acad. Sci. USA 109:19327-19322.

2011

2010

  • Bowler, C.P., Vardi, A. and Allen, A.E. (2010) Oceanographic and biogeochemical insights from diatom genomes. Annual Reviews in Marine Sciences. 2: 333-365.
  • Maheswari U., Jabbari K., Petit J.L., Porcel B.M., Allen A.E., Cadoret J.P., [...], Vardi A., Armbrust E.V., Weissenbach J., Katinka M. and Bowler C. (2010) Digital expression profiling of novel diatom transcripts provides insight into their biological functions. Genome Biology 11(8): R85

2009

  • Vardi, A., Van Mooy, B.A.S., Fredericks, H.F., Popendorf, K, Ossolinski, J, Haramaty, L. and Bidle, K.D. (2009) Viral glycosphingolipids induce lytic infection and cell death in marine phytoplankton. Science 326, 861 (2009).
  • Maumus, F., Allen, A., Mhiri, C., Hu, H., Jabbari, K., Vardi, A., Grandbastien, M.A. and Bowler, C. (2009) Potential impact of stress activated retrotransposons on genome evolution in a marine diatom. BMC Genomics. 10:624 doi:10.1186/1471-2164-10-624.

2008

  • Vardi, A, Thamatrakoln, K, Bidle, K.D. and Falkowski, P.G. (2008) Diatom genomes come of age. Genome Biology 9(12):245.
  • Vardi A (2008) Cell signaling in marine diatoms. Communicative & Integrative Biology 1(2): 134.
  • Bowler C., […], Vardi A., Grigoriev IV. (2008) The Phaeodactylum genome reveals the evolutionary history of diatom genomes. Nature. 456:239-244.
  • Andrianasolo EH, Haramaty L, Vardi A, White E, Lutz R and Falkowski PG. (2008) Apoptosis Inducer Galactolipids from a Cultured Marine Diatom Phaeodactylum tricornutum. Journal of Natural Products 71 (7):1197–1201.
  • Vardi A, Bidle KD, Kwityn C, Thompson SM, Callow JA, Falkowski PG, Bowler C (2008). A Diatom Gene Regulating Nitric Oxide Signaling and Susceptibility to Diatom-Derived Aldehydes. Current Biology 18(12):895-9.
  • Kahl, A.L., Vardi, A. and Schofield, O. (2008). The effect of phytoplankton physiology on export flux. Marine Ecology Progress Series (Feature Article) 354: 3-19.

2007

  • Vardi, A., Eisenstadt, D., Murik, O., Berman-Frank, I., Zohary, T., Kaplan, A., and Levine, A. (2007). Synchronization of cell death in a dinoflagellate population is mediated by an extracreted thiol protease. Environmental Microbiology 9 (2): 360–369.
  • Montsant, A., […],Vardi, A […], Bowler, B. (2007). Identification and comparative genomic analysis of signaling and regulatory components in the diatom Thalassiosira pseudonana. Journal of Phycology 43(3): 585-604.
  • Schatz, D., Keren, Y., Vardi, A., Sukenik, A., Carmeli, S., Börner, T., Dittmann E., and Kaplan, A. (2007). Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environmental Microbiology 9(4), 965–970.

2006

  • Vardi, A., Formiggini, F., Casotti, R., de Martino, A., Ribalet, F., Miralto, A., and  Bowler, C. (2006). A stress surveillance system based on calcium and nitric oxide in marine diatoms. PLoS Biology 4(3):e60.
  • Allen, A.E., Vardi, A., Bowler, C.P. (2006). An ecological and evolutionary context for integrated nitrogen metabolism and cell signaling pathways in marine diatoms. Current Opinion in Plant Biology 9 (3):264-273.

2004

  • Armbrust, E.V, […],Vardi, A., Wilkerson, F.P, and. Rokhsar D. S. (2004). The genome of the diatom Thalassiosira pseudonana: Ecology, evolution and metabolism. Science 306: 79-86.

2002

  • Vardi, A., Schatz, D., Beeri,K., Motro, U., Sukenik, A., Levine, A., Kaplan, A.. (2002) Dinoflagellate-cyanobacterium communication may determine the composition of phytoplankton assemblage in a mesotrophic lake. Current Biology. 12: 1767-1772.
  • Sukenik, A., Eshkol, R., Livne, A., Hadas, O., Rom, M., Tchernov, D., Vardi, A., Kaplan, A. (2002). Inhibition of growth and photosynthesis of the dinoflagellate Peridinium gatunense by Microcystis sp. (cyanobacteria): A novel allelopathic mechanism. Limnology and Oceanography 47(6): 1656–1663.

1999

  • Hadas, O., Pinkas, R., Delphine, E., Vardi, A., Kaplan, A. Sukenik, A. (1999) Limnological and ecological aspects of Aphanizomenon ovalisporum bloom in Lake Kinneret, Israel. J. Plankton Research. 21: 1439-1453.
  • Vardi, A., Berman-Frank, I., Rozenberg, T., Hadas, O., Kaplan, A., Levine, A. (1999) Programmed cell death of the bloom-forming dinoflagellate Peridinium gatunense is mediated by CO2 limitation and oxidative stress. Current Biology. 9: 1061-1064.