Selected Publications

  • Palty, R., Raveh, A., Kaminsky, I., Meller, R. and Reuveny, E. (2012) SARAF Inactivates the Store Operated Calcium Entry Machinery to Prevent Excess Calcium Refilling. Cell In Press.
  • Cooper, A., Grigoryan, G., Guy-David, L., Tsoory, M., Chen, A. and Reuveny, E. (2012) Trisomy of the G-protein coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions and synaptic plasticity in mice. PNAS In Press.
  • Raveh, A., Cooper, A., Guy-David, L. and Reuveny, E. (2010) Nonenzymatic rapid control of GIRK channel function by a G protein-coupled receptor kinase. Cell 143, 750-760.
  • Raveh, A., Riven, I., and Reuveny, E. (2009). Elucidation of the gating of the GIRK channel using a spectroscopic approach. J Physiol. 587 (Pt 22), 5331-5.
  • Sadja, R., and Reuveny, E. (2009). Activation gating kinetics of GIRK channels are mediated by cytoplasmic residues adjacent to transmembrane domains. Channels (Austin) 3(3), 205-14.
  • Raveh, A., Riven, I., and Reuveny, E. (2008) The use of FRET microscopy to elucidate steady state channel conformational rearrangements and G protein interaction with the GIRK channels. Methods Mol Biol. 491, 199-212.
  • Iwanir, S., and Reuveny, E. (2008). Adrenaline-induced hyperpolarization of mouse pancreatic islet cells is mediated by G protein-gated inwardly rectifying potassium (GIRK) channels. Pflugers Arch. 456(6), 1097-108.
  • Guy-David, L., and Reuveny, E. (2007). PIP2–the master key. Neuron 55, 537-538.
  • Riven, I., Iwanir, S., and Reuveny, E. (2006). GIRK channel activation involves a local rearrangement of a preformed G protein channel complex. Neuron 51, 561-573.
  • Wiser, O., Qian, X., Ehlers, M., Ja, W. W., Roberts, R. W., Reuveny, E., Jan, Y. N., and Jan, L. Y. (2006). Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN. Neuron 50, 561-573.
  • Riven, I., Kalmanzon, E., Segev, L., and Reuveny, E. (2003). Conformational rearrangements associated with the gating of the G protein-coupled potassium channel revealed by FRET microscopy. Neuron 38, 225-235.
  • Chatelain, F.C., Alagem, N., Xu, Q., Pancaroglu, R., Reuveny, E., and Minor, D.L., Jr. (2005). The pore helix dipole has a minor role in inward rectifier channel function. Neuron 47, 833-843.
  • Sadja, R., Alagem, N., and Reuveny, E. (2003). Gating of GIRK channels: details of an intricate, membrane-delimited signaling complex. Neuron 39, 9-12.
  • Alagem, N., Yesylevskyy, S., and Reuveny, E. (2003). The pore helix is involved in stabilizing the open state of inwardly rectifying K+ channels. Biophysical journal 85, 300-312.
  • Sadja, R., Alagem, N., and Reuveny, E. (2002). Graded contribution of the Gbeta gamma binding domains to GIRK channel activation. Proc Natl Acad Sci U S A 99, 10783-10788.
  • Sadja, R., Smadja, K., Alagem, N., and Reuveny, E. (2001). Coupling Gbetagamma-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels. Neuron 29, 669-680.
  • Alagem, N., Dvir, M., and Reuveny, E. (2001). Mechanism of Ba2+ block of a mouse inwardly rectifying K+ channel: differential contribution by two discrete residues. The Journal of physiology 534, 381-393.
  • Zeidner, G., Sadja, R., and Reuveny, E. (2001). Redox-dependent gating of G protein-coupled inwardly rectifying K+ channels. J Biol Chem 276, 35564-35570.
  • Sadja R., Smadja, K. Alagem, N. and Reuveny, E. Coupling Gbg-dependent activation to channel opening via pore elements in inwardly rectifying potassium channels. Neuron 29, 669-680 (2001).
  • Alagem, N., Devir, M. and Reuveny, E. Mechanism of Ba2+ block of inwardly rectifying K+ channel: Differential contribution by two discrete residues. J. Physiol. 534.2 381-393 (2001).
  • Ford, C.E., Skiba, N.P. Bae, H., Daaka, Y., Reuveny, E., Shekter, L.R., Rossal, R., Weng, W., Yang, C.S., Iyengar, R., Miller, R.J., Jan, L.Y., Lefkowitz, R.J. and  Hamm, H.E. Molecular basis for interactions of G protein bg subunits with effectors. Science, 280, 1271-1274 (1998).