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Ferritin as a reporter gene for MRI

Batya Cohen, Hagit Dafni, Gila Meir, Alon Harmelin and Michal Neeman

(Batya Cohen , 2007)

Ferritin as a reporter gene for MRI. Tetracycline regulated expression of EGFP-HAferritin in C6 glioma tumors implanted in nude mice. Top) Fluorescence of EGFP; Bottom) MRI derived maps of R2 relaxation rates. Left) Animals drinking tetracycline supplemented water, expression of the transgene is suppressed. Right) Animals not treated with tetracycline, over expression of EGFP and HAferritin. Cohen et al 2005.

 

Responder Transgenic Line