Events

  • Date:
    19

    Tuesday

    September 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: How did the protoribosomes form the first peptide bonds – chemical and structural studies

    Dr. Tanaya Bose, Yonath Lab, Dept. of Chemical and Structural Biology, Weizmann Institute

  • Date:
    04

    Monday

    September 2023

    Hour: 10:00 - 11:00,Location: Nella and Leon Benoziyo Building for Biological Sciences
    Event name: High-speed atomic force microscopy captures a rare oligomeric state of an ion channel

    Dr. Shifra Lansky, Cornell University, New York

    Transient receptor potential (TRP) channels are a large, eukaryotic ion-channel superfamily that control diverse physiological functions. To date, more than 210 structures from over 20 TRP-channels have been determined, all are tetramers. Using high-speed atomic force microscopy (HS-AFM), a pioneering technique capable of “filming” single-molecule proteins, we discovered a rare and transient pentameric state for TRPV3, and determined the pentamer structure using single-particle cryo-EM. Our results suggest that the pentamer relates to the pore-dilated state, a structurally-elusive state characterized by increased conductance and permeability to small molecules. These findings lay the foundation for many new directions in ion-channel research, and demonstrate the strength of HS-AFM in discovering transient and rare states of proteins.

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  • Date:
    15

    Tuesday

    August 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Intra-host evolution of HIV env after broadly-neutralizing antibody infusion

    Dr. Frida Belinky, Virus Persistence and Dynamics Section Immunology Laboratory Vaccine Research Center National Institute of Allergy and Infectious Diseases National Institutes of Health

  • Date:
    27

    Tuesday

    June 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Functional studies of lysine ac(et)ylation using genetically encoded post-translational modifications

    Prof. Eyal Arbely, Department of Chemistry Ben Gurion University

  • Date:
    22

    Thursday

    June 2023

    Hour: 11:00 - 12:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Quo Vadis Small Molecule Drug Discovery?

    Dr. Ingo Hartung, Head of Medicinal Chemistry & Drug Design Global Research & Development Merck Healthcare KGaA

  • Date:
    13

    Tuesday

    June 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Translational Chemical Biology

    Prof. Xiaoguang Lei, Peking University

  • Date:
    06

    Tuesday

    June 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Microbiome Metabolites: Syntheses and Surprises

    Prof. Karl Gademann, Department of Chemistry University of Zurich

  • Date:
    30

    Tuesday

    May 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Electrosome assembly: a first look at the structural principles underlying ion channel biogenesis

    Prof. Daniel Minor, Departments of Biochemistry & Biophysics University of California San Francisco

  • Date:
    23

    Tuesday

    May 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Advances of Liquid Biopsy Diagnostics and Structural Models in the Development of Data-Driven AI in Future Hospitals

    Dr. Milana Frenkel-Morgenstern, Azrieli Faculty of Medicine Bar-Ilan University

  • Date:
    15

    Monday

    May 2023

    Hour: 11:00 - 12:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: KENDREW LECTURE: Computational Structural Biology in the Era of Deep Learning

    Prof. John Moult, Institute of Bioscience and Biotechnology Research Department of Cell Biology and Molecular Genetics University of Maryland

  • Date:
    02

    Tuesday

    May 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Conspiring with the Enemy: A Unique Mechanism in Class A JDPs Stabilizes Oncogenic p53 Mutants

    Guy Zoltsman, Dept. of Chemical & Structural Biology Weizmann Institute

  • Date:
    18

    Tuesday

    April 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Structural Biology Response to Biomedical Threats

    Prof. Wladek Minor, Department of Molecular Physiology and Biological Physics University of Virginia

  • Date:
    02

    Sunday

    April 2023

    Hour: 11:00 - 12:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Fluorescent nucleosides, nucleotides and oligonucleotides

    Prof. Yitzhak Tor, University of California San Diego

  • Date:
    28

    Tuesday

    March 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Intestinal mucin is a chaperone of multivalent copper

    Nava Reznik, Fass Lab Dept. of Chemical & Structural Biology Weizmann Institute

  • Date:
    15

    Wednesday

    March 2023

    Hour: 11:00 - 12:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Towards resolving dynamics of molecular machines using time-resolved cryo-EM

    Prof. Rouslan Efremov, VIB-VUB Center for Structural Biology Belgium

  • Date:
    14

    Tuesday

    March 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Structure-based prediction of protein-protein and protein compound interactions on a proteome-wide scale

    Prof. Barry Honig, Columbia University

  • Date:
    28

    Tuesday

    February 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Fast and Processive Artificial Molecular Motors and Rotors Made of DNA

    Prof. Eyal Nir, Department of Chemistry Ben-Gurion University

  • Date:
    31

    Tuesday

    January 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Chemical Evolution: From Origins of Life to Biotechnology

    Dr. Moran Frenkel-Pinter , Institute of Chemistry The Hebrew University of Jerusalem

  • Date:
    24

    Tuesday

    January 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Intrinsically disordered proteins can also exhibit millisecond conformational dynamics

    Dr. Eitan Lerner, The Alexander Silberman Institute of Life Sciences The Hebrew University

  • Date:
    17

    Tuesday

    January 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: Rational discovery of selective chemical probes of the polyamine deacetylase HDAC10

    Dr. Aubry Miller, Cancer Drug Development German Cancer Research Center DKFZ, Germany

  • Date:
    12

    Thursday

    January 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: GPCR structure and dynamics - Insights from Rhodopsin

    Prof. Oliver P. Ernst, University of Toronto Canada

  • Date:
    03

    Tuesday

    January 2023

    Hour: 14:00 - 15:00,Location: Gerhard M.J. Schmidt Lecture Hall
    Event name: The Simple QTY Code for Protein Design

    Prof. Shuguang Zhang, MIT Media Lab USA