The LCRB is seeking a highly motivated candidate in the field of NMR spectroscopy


The Laboratory of Biological Crystallography and NMR (LCRB) is seeking a highly motivated candidate in the field of NMR spectroscopy to set up a new team. The LCRB is part of the Pharmacy Faculty of the University Paris Descartes located in the center of Paris. The local research environment is geared towards pharmaceutical sciences (drug design, synthesis, formulation, function, …). Research at the LCRB is focused on structural and functional studies of biological systems involved in human health.

Candidates are expected to develop a research activity in the field of NMR spectroscopy in line with the lab’s interests, including macromolecule structural studies (proteins, DNA/RNA, membrane proteins...) as well as protein-protein, protein-DNA/RNA or protein-drug interactions. Candidates should be open to projects in drug screening by NMR, metabolomics and study of complex mixtures. Integrative structural biology projects involving other biophysical and biochemical methods are welcome. The project should highlight the benefits of working within the Faculty of Pharmacy of Paris Descartes and put forward possible collaborative projects.

Candidates will have access to state-of-the-art shared core facilities, including protein production and purification lab, crystallization screening robots, and privileged access to the lab's recently renewed 600 MHz Bruker NMR spectrometer equipped with a cryoprobe. The candidate could benefit from redeployment of permanent staff (NMR engineers, CR, MCU) in the laboratory to strengthen his team. Selected candidates will have access to office and lab space for their team, to all LCRB and local facilities and to the CACSICE Equipex facilities: SAXS in the LCRB, 700MHz NMR and Mass spectroscopy at the IBPC, cryo-EM microscopy at the Pasteur Institute.


Candidates are required to have permanent French research position (University, CNRS or INSERM) or alternatively should meet the criteria required to apply for permanent positions and/or for national and international funding (ATIP/Avenir, ERC, ANR JCJC...). Applications should include a cover letter explaining the interest of the candidate in joining the LCRB, a CV, contact information for three references and a description of achievements and of future research programs. Candidates will be invited to visit the lab and present their current and future research plans.


Please send all information as a single file to Pr. Nicolas Leulliot