PhD fellowship at Ecole Normale Supérieure, Paris - Functional dynamics of IDPs by NMR

A three-year PhD fellowship funded by ANR is available to work in our group at Ecole Normale Supérieure, PSL University, Paris.

Project: Nanometric motions in disordered proteins of DNA double-strand break repair by NMR

The discovery of intrinsically disordered proteins and regions (IDPRs) challenges our understanding of the physical chemistry of biological mechanisms. IDPRs increase the reach of biomolecular systems to project far and engage in multiple interactions, moving efficiently over nanometer distances.
We will use innovative NMR methods and instruments to investigate the geometry and timescales of motions in IDPRs with high resolution. This methodology will be developed on the IDPRs from key proteins in the non-homologous end joining (NHEJ) pathway, a process essential for the repair of DNA double-strand breaks and adaptive immunity.

Starting date: October 1st 2019.

How to apply? Send a cover letter, CV, and names of three references to Fabien.Ferrage@ens.fr

Best regards,
Fabien Ferrage

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Fabien Ferrage

Research Director @CNRS

Associate Professor @ENS

NMR team - Laboratoire des biomolecules

Department of Chemistry

Ecole normale superieure

PSL University

24, rue Lhomond

75231 Paris Cedex 05

France

tel: (33) 1 44 32 33 43

http://www.paris-en-resonance.fr/index.php